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The map label for this gene is 66045267

Identifier: 66045267

GI number: 66045267

Start: 2351440

End: 2352294

Strand: Direct

Name: 66045267

Synonym: Psyr_2027

Alternate gene names: NA

Gene position: 2351440-2352294 (Clockwise)

Preceding gene: 66045266

Following gene: 66045268

Centisome position: 38.59

GC content: 62.81

Gene sequence:

>855_bases
GTGACGTTTAGCGTGGAGGAAGTGCGTTTCAATCTGGGGCATATCGAACTGGCTGCCCATCTTTACGGCCCCGAGGACGG
CCGGCCGGTGATTGCCGTGCACGGCTGGCTCGACAATGCCAACAGCTTTGCCCGCCTGGCGCCGCAACTGGATGGCCTGC
GCATCGTGGCGCTCGATCTGGCCGGGCATGGTCATTCAGCGCATAGGCCTGCCGGGGCGTCCTATGCGCTGGCCGACTAC
GTGTTCGACGTGCTGCAGGTCGCCGAGCAATTGGGCTGGCAGCGCTTTGCCCTGATGGGCCATTCACTGGGCGCGATCAT
TTCGGTATTGCTGGCCGGGTCGTTGCCGGAGCGTGTCACGCGGCTGGCACTGATCGACGGTTTGATTCCCTTGACCGGCG
ACCCCGAATCCGCCGCCGAGCGGATGGGCTCCGCGCTGCAGGCGCAGCTCAGGCTGTCGGGCAAGAAAAAGCCGGTTTAC
GAGGATCAGCAACGCGCTGTTCAGGCGCGTATGAAAGGCGTCGTCCCGGTCAGTCGCGAGGCTGCCGAATTACTCGCGCA
ACGCGGCCTGATGCCGGTACCCGGCGGCTATACCTGGCGCAGCGACAGCCGCCTGACGCTGCCATCTGCGATACGTCTTA
CACATCAGCAGGCGATGTCTTTCGTCAACGCTATCCGTTGCCCGACGCAACTGCTGGTCGCTACAGGCGGCATGCTGACG
AAAAATCAGCTCATGCTGTCCGGGCTGCCTTTCGACGTCGTGCAGCTTGAAGGCGGTCATCATCTGCACCTGGACGACGA
GCAGGGCGCGAGCGCTGTTGCACACTGTATCAATCGCTTCTTCGCTGCTTCTTGA

Upstream 100 bases:

>100_bases
GAGGGCACATGTTTCCCCTTGAACGACCGGATGAAACCGCATGGCTGCTCAAAACGCTGCTGGCTCGCTGGGACGCGCGT
AGCGCCTCAAGGTTGACGGC

Downstream 100 bases:

>100_bases
CTTGAGCCCGGCAACTGCCGACGCTGGGCGGGTTGAAACAGGAGTCAACCGTGATGGATCAATCCGCAGCCTCTGGTGAC
CGCCTCGCTGGCGATCTTTT

Product: Alpha/beta hydrolase fold

Products: NA

Alternate protein names: Atropine acylhydrolase; Atropinesterase [H]

Number of amino acids: Translated: 284; Mature: 283

Protein sequence:

>284_residues
MTFSVEEVRFNLGHIELAAHLYGPEDGRPVIAVHGWLDNANSFARLAPQLDGLRIVALDLAGHGHSAHRPAGASYALADY
VFDVLQVAEQLGWQRFALMGHSLGAIISVLLAGSLPERVTRLALIDGLIPLTGDPESAAERMGSALQAQLRLSGKKKPVY
EDQQRAVQARMKGVVPVSREAAELLAQRGLMPVPGGYTWRSDSRLTLPSAIRLTHQQAMSFVNAIRCPTQLLVATGGMLT
KNQLMLSGLPFDVVQLEGGHHLHLDDEQGASAVAHCINRFFAAS

Sequences:

>Translated_284_residues
MTFSVEEVRFNLGHIELAAHLYGPEDGRPVIAVHGWLDNANSFARLAPQLDGLRIVALDLAGHGHSAHRPAGASYALADY
VFDVLQVAEQLGWQRFALMGHSLGAIISVLLAGSLPERVTRLALIDGLIPLTGDPESAAERMGSALQAQLRLSGKKKPVY
EDQQRAVQARMKGVVPVSREAAELLAQRGLMPVPGGYTWRSDSRLTLPSAIRLTHQQAMSFVNAIRCPTQLLVATGGMLT
KNQLMLSGLPFDVVQLEGGHHLHLDDEQGASAVAHCINRFFAAS
>Mature_283_residues
TFSVEEVRFNLGHIELAAHLYGPEDGRPVIAVHGWLDNANSFARLAPQLDGLRIVALDLAGHGHSAHRPAGASYALADYV
FDVLQVAEQLGWQRFALMGHSLGAIISVLLAGSLPERVTRLALIDGLIPLTGDPESAAERMGSALQAQLRLSGKKKPVYE
DQQRAVQARMKGVVPVSREAAELLAQRGLMPVPGGYTWRSDSRLTLPSAIRLTHQQAMSFVNAIRCPTQLLVATGGMLTK
NQLMLSGLPFDVVQLEGGHHLHLDDEQGASAVAHCINRFFAAS

Specific function: Alkaloid degradation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dmpD/todF/xylF esterase family [H]

Homologues:

Organism=Homo sapiens, GI18777795, Length=282, Percent_Identity=29.4326241134752, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24667999, Length=292, Percent_Identity=30.4794520547945, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI21357291, Length=286, Percent_Identity=27.2727272727273, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24667992, Length=286, Percent_Identity=27.2727272727273, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24655874, Length=273, Percent_Identity=31.5018315018315, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI21356953, Length=282, Percent_Identity=29.7872340425532, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI17137390, Length=279, Percent_Identity=30.1075268817204, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24655886, Length=119, Percent_Identity=42.8571428571429, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI21356937, Length=294, Percent_Identity=25.8503401360544, Blast_Score=97, Evalue=9e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.1.1.10 [H]

Molecular weight: Translated: 30643; Mature: 30511

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFSVEEVRFNLGHIELAAHLYGPEDGRPVIAVHGWLDNANSFARLAPQLDGLRIVALDL
CCCCHHHHHHCCCCEEEEEEECCCCCCCEEEEEECCCCCCCHHHHHCCCCCCEEEEEEEE
AGHGHSAHRPAGASYALADYVFDVLQVAEQLGWQRFALMGHSLGAIISVLLAGSLPERVT
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCHHHHH
RLALIDGLIPLTGDPESAAERMGSALQAQLRLSGKKKPVYEDQQRAVQARMKGVVPVSRE
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCHH
AAELLAQRGLMPVPGGYTWRSDSRLTLPSAIRLTHQQAMSFVNAIRCPTQLLVATGGMLT
HHHHHHHCCCCCCCCCCEECCCCCEECHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCEE
KNQLMLSGLPFDVVQLEGGHHLHLDDEQGASAVAHCINRFFAAS
CCCCEECCCCEEEEEECCCCEEECCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TFSVEEVRFNLGHIELAAHLYGPEDGRPVIAVHGWLDNANSFARLAPQLDGLRIVALDL
CCCHHHHHHCCCCEEEEEEECCCCCCCEEEEEECCCCCCCHHHHHCCCCCCEEEEEEEE
AGHGHSAHRPAGASYALADYVFDVLQVAEQLGWQRFALMGHSLGAIISVLLAGSLPERVT
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCHHHHH
RLALIDGLIPLTGDPESAAERMGSALQAQLRLSGKKKPVYEDQQRAVQARMKGVVPVSRE
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCHH
AAELLAQRGLMPVPGGYTWRSDSRLTLPSAIRLTHQQAMSFVNAIRCPTQLLVATGGMLT
HHHHHHHCCCCCCCCCCEECCCCCEECHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCEE
KNQLMLSGLPFDVVQLEGGHHLHLDDEQGASAVAHCINRFFAAS
CCCCEECCCCEEEEEECCCCEEECCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA