Click here to switch to the map view.

The map label for this gene is frzE [H]

Identifier: 66044555

GI number: 66044555

Start: 1482580

End: 1484949

Strand: Direct

Name: frzE [H]

Synonym: Psyr_1307

Alternate gene names: 66044555

Gene position: 1482580-1484949 (Clockwise)

Preceding gene: 66044554

Following gene: 66044556

Centisome position: 24.33

GC content: 62.53

Gene sequence:

>2370_bases
ATGACGCCAGATCAAATGCGTGACGCCTCGCTGTTCGAACTGTTCACGCTGGAAGCCGATGCGCAGACCCAGGTACTGAG
TGCCGGCCTGCTGGCACTCGAACGTAACCCGACCCAGGCGGATCAGCTGGAAGCCTGCATGCGTGCCGCTCATTCGCTCA
AGGGCGCAGCGCGGATTGTCGGCGTCGATTTCGGCGTGAGCGTCGCGCATGTGATGGAAGATTGTCTGGTCAGCGCGCAG
GAAGGGCGTCTGCTGCTTCAGGCCGAGCATATCGATGCGCTGCTGTCGGGGACCGACCTGTTGATGCGTATCGCCACGCC
TGGCGGCGACAGCGTTGGTCAGCCTGATATCGACAGTTATGTCGAAAGGCTCAATACGTTGCTGGCTTCCGGTGCTGGCG
CGGCGCGAACGGTCAGTACGCCACTGCCGGACCCGGCCTCGGACGCTTTACTCGCCAGCGCGATGCTGCAGTTCGAGACG
CCCAGCGCGGCAGTTGTGCCGGAGTCTGTGCCCGAGCCCTTGGCCGCAGACTTGCCTGCGTCCGCCAATCCAGCCGCCAT
GCCGGCTGCGGAACCTGAAGCACCGTTCACGCCATTGCGTGAACGGCGTGTGGCCGAAGGTGGCGAGCGCGTGTTGCGAG
TCACCGCCGAGCGCCTCAACGGGCTGCTGGACATGTCCAGCAAATCGCTGGTCGAGACTCAGCGACTCAAGCCGCTGCTG
GCCGGTATGCAGCGGCTCAAGCGTCTGCAAAGCAGCAGTGATCGTGCGCTTGAAGTGCTGGGCGCCAGCTTCGGCGAGGA
AGGTCCTTCGGCTGATGTGCAAAAAGCCCTGGAAGACGCGCGTAGCCTCTTGTCCCAGGCGCAGCAGGTGTTGGTCCGGC
ACACTGCCGAGCTGGATGAATTCGGCTGGCAGTCGGCGCAACGTGCGCAGTTGTTATACGACACGGCACTGGCCTGCCGG
ATGCGACCTTTCGCCGATGTGCTGAACGGCCAGGCGCGCATGGTTCGCGACCTGGGGCGTGAACTGGGCAAACAGGTCCG
CTTGCAGATCGAAGGCGAGAAGACGCAGGTCGATCGCGATGTGCTGGAAAAGCTCGATGCGCCATTGACCCATCTGTTGC
GCAACGCCGTGGACCACGGCATCGAATCGCCCGAGAAGCGCGTGGCGTCCGGCAAGGACCCTGAAGGTCTGATTCGTCTG
CAGGCCTCGCATCAGGCCGGCTTGCTGGTCGTCGAGTTGAGCGATGACGGTGGCGGTGTGGACCTTGAACGTGTGCGCCA
GAGCATCGTCGACCGCAAGCTTTCTCCTGCCGAGACCGCTGCGCAGTTGAGCGAGGAGGAACTGCTGAGTTTCCTGTTCC
TGCCGGGCTTCAGCATGCGCGACAAGGTCACGCAGATTTCCGGCCGTGGTGTCGGCCTCGATGCCGTGCAGCATATGGTT
CGCCAGATGCACGGCAGCGTCGAGCTGCAGCAATGGGCAGGCGAGGGCAGTCGCTTCAGGATAGAAATGCCGCTGACGCT
TTCAGTGGTACGCAGCCTGGTCGTGGAAGTGGGCGGTGAAGCCTATGCCTTTCCGCTGGCGCATATCGAGCGCATGCGCG
ACCTGCAGCCTGACGATATTCTGCAACTGGAAGGGCGTCAGCACTTCTGGGATGAAGAGCGGCATGTCGGTCTGGTTTCG
GCCAGCCAGCTGTTGAACCGGCCACCCGCGCAGAAGGCCGGAGAAACGCTCAAGGTCGTGGTGATTCGCGAGCGCGATGC
GGTTTATGGCGTGGCCGTCGAACGCTTCATCGGTGAGCGTACGCTGGTGGTGATGCCGCTCGATGCGCGCCTTGGCAAGG
TCCAGGACGTGTCGGCAGGGGCCTTGCTCGACGACGGTTCAGTGGTGTTGATCATCGATGTCGAAGATATGCTGCGCTCG
GTGGAAAAACTCCTGAATACCGGCCGTCTGGAGCGCATCGACCGGCGCGCTCGTCAGGCAGATCAGGTGTCACGCAAACG
CGTGCTGGTCGTCGATGATTCTTTGACCGTTCGCGAGCTGGAACGCAAGCTGCTGGTCAGTCGCGGTTACGAAGTATCGG
TGGCCGTGGACGGAATGGATGGCTGGAATGCCCTGCGCGCCGAGGACTTCGACCTGCTGATCACCGACATCGACATGCCG
CGTATGGACGGTATCGAACTGGTGACCCTGTTGCGCCGCGATACCCGCTTGCAGTCCTTGCCGGTCATGGTCGTGTCCTA
CAAGGACCGCGAAGAAGACCGGCGTCGCGGCCTGGACGCCGGCGCCGATTATTACCTGGCCAAGGCCAGTTTCCACGATG
ATGCCTTGCTCGACGCTGTCGTCGAATTGATAGGAGACGCGCAAGGATGA

Upstream 100 bases:

>100_bases
CCAATGCCCGTTTCACCCGTGGCGTCCTGCAATGGAAGGGCCGCAGCCTGCGCTGGCTGGATGAAGATGAGTTGTTGTCG
GCGGTGTATCGGAGCCTCAC

Downstream 100 bases:

>100_bases
AGATTGCCATCGTCAACGATATGCCCATGGCCATCGAAGCCCTGCGCCGTGCGCTGGCCTTCGAGCCCGCGCATCAGATC
ATCTGGGTGGCGTCCAATGG

Product: response regulator receiver:CheW-like protein:ATP-binding region, ATPase-like:Hpt

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 789; Mature: 788

Protein sequence:

>789_residues
MTPDQMRDASLFELFTLEADAQTQVLSAGLLALERNPTQADQLEACMRAAHSLKGAARIVGVDFGVSVAHVMEDCLVSAQ
EGRLLLQAEHIDALLSGTDLLMRIATPGGDSVGQPDIDSYVERLNTLLASGAGAARTVSTPLPDPASDALLASAMLQFET
PSAAVVPESVPEPLAADLPASANPAAMPAAEPEAPFTPLRERRVAEGGERVLRVTAERLNGLLDMSSKSLVETQRLKPLL
AGMQRLKRLQSSSDRALEVLGASFGEEGPSADVQKALEDARSLLSQAQQVLVRHTAELDEFGWQSAQRAQLLYDTALACR
MRPFADVLNGQARMVRDLGRELGKQVRLQIEGEKTQVDRDVLEKLDAPLTHLLRNAVDHGIESPEKRVASGKDPEGLIRL
QASHQAGLLVVELSDDGGGVDLERVRQSIVDRKLSPAETAAQLSEEELLSFLFLPGFSMRDKVTQISGRGVGLDAVQHMV
RQMHGSVELQQWAGEGSRFRIEMPLTLSVVRSLVVEVGGEAYAFPLAHIERMRDLQPDDILQLEGRQHFWDEERHVGLVS
ASQLLNRPPAQKAGETLKVVVIRERDAVYGVAVERFIGERTLVVMPLDARLGKVQDVSAGALLDDGSVVLIIDVEDMLRS
VEKLLNTGRLERIDRRARQADQVSRKRVLVVDDSLTVRELERKLLVSRGYEVSVAVDGMDGWNALRAEDFDLLITDIDMP
RMDGIELVTLLRRDTRLQSLPVMVVSYKDREEDRRRGLDAGADYYLAKASFHDDALLDAVVELIGDAQG

Sequences:

>Translated_789_residues
MTPDQMRDASLFELFTLEADAQTQVLSAGLLALERNPTQADQLEACMRAAHSLKGAARIVGVDFGVSVAHVMEDCLVSAQ
EGRLLLQAEHIDALLSGTDLLMRIATPGGDSVGQPDIDSYVERLNTLLASGAGAARTVSTPLPDPASDALLASAMLQFET
PSAAVVPESVPEPLAADLPASANPAAMPAAEPEAPFTPLRERRVAEGGERVLRVTAERLNGLLDMSSKSLVETQRLKPLL
AGMQRLKRLQSSSDRALEVLGASFGEEGPSADVQKALEDARSLLSQAQQVLVRHTAELDEFGWQSAQRAQLLYDTALACR
MRPFADVLNGQARMVRDLGRELGKQVRLQIEGEKTQVDRDVLEKLDAPLTHLLRNAVDHGIESPEKRVASGKDPEGLIRL
QASHQAGLLVVELSDDGGGVDLERVRQSIVDRKLSPAETAAQLSEEELLSFLFLPGFSMRDKVTQISGRGVGLDAVQHMV
RQMHGSVELQQWAGEGSRFRIEMPLTLSVVRSLVVEVGGEAYAFPLAHIERMRDLQPDDILQLEGRQHFWDEERHVGLVS
ASQLLNRPPAQKAGETLKVVVIRERDAVYGVAVERFIGERTLVVMPLDARLGKVQDVSAGALLDDGSVVLIIDVEDMLRS
VEKLLNTGRLERIDRRARQADQVSRKRVLVVDDSLTVRELERKLLVSRGYEVSVAVDGMDGWNALRAEDFDLLITDIDMP
RMDGIELVTLLRRDTRLQSLPVMVVSYKDREEDRRRGLDAGADYYLAKASFHDDALLDAVVELIGDAQG
>Mature_788_residues
TPDQMRDASLFELFTLEADAQTQVLSAGLLALERNPTQADQLEACMRAAHSLKGAARIVGVDFGVSVAHVMEDCLVSAQE
GRLLLQAEHIDALLSGTDLLMRIATPGGDSVGQPDIDSYVERLNTLLASGAGAARTVSTPLPDPASDALLASAMLQFETP
SAAVVPESVPEPLAADLPASANPAAMPAAEPEAPFTPLRERRVAEGGERVLRVTAERLNGLLDMSSKSLVETQRLKPLLA
GMQRLKRLQSSSDRALEVLGASFGEEGPSADVQKALEDARSLLSQAQQVLVRHTAELDEFGWQSAQRAQLLYDTALACRM
RPFADVLNGQARMVRDLGRELGKQVRLQIEGEKTQVDRDVLEKLDAPLTHLLRNAVDHGIESPEKRVASGKDPEGLIRLQ
ASHQAGLLVVELSDDGGGVDLERVRQSIVDRKLSPAETAAQLSEEELLSFLFLPGFSMRDKVTQISGRGVGLDAVQHMVR
QMHGSVELQQWAGEGSRFRIEMPLTLSVVRSLVVEVGGEAYAFPLAHIERMRDLQPDDILQLEGRQHFWDEERHVGLVSA
SQLLNRPPAQKAGETLKVVVIRERDAVYGVAVERFIGERTLVVMPLDARLGKVQDVSAGALLDDGSVVLIIDVEDMLRSV
EKLLNTGRLERIDRRARQADQVSRKRVLVVDDSLTVRELERKLLVSRGYEVSVAVDGMDGWNALRAEDFDLLITDIDMPR
MDGIELVTLLRRDTRLQSLPVMVVSYKDREEDRRRGLDAGADYYLAKASFHDDALLDAVVELIGDAQG

Specific function: FrzE is involved in a sensory transduction pathway that controls the frequency at which cells reverse their gliding direction. FrzE seems to be capable of autophosphorylating itself on an histidine residue and then to transfer that group to an aspartate r

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=359, Percent_Identity=35.6545961002786, Blast_Score=220, Evalue=3e-58,
Organism=Escherichia coli, GI1788191, Length=103, Percent_Identity=38.8349514563107, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI1788713, Length=117, Percent_Identity=34.1880341880342, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1786599, Length=103, Percent_Identity=33.9805825242718, Blast_Score=63, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR011006
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR005467
- InterPro:   IPR001789 [H]

Pfam domain/function: PF01584 CheW; PF02518 HATPase_c; PF01627 Hpt; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 86372; Mature: 86240

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPDQMRDASLFELFTLEADAQTQVLSAGLLALERNPTQADQLEACMRAAHSLKGAARIV
CCCCHHCCCHHHHEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEE
GVDFGVSVAHVMEDCLVSAQEGRLLLQAEHIDALLSGTDLLMRIATPGGDSVGQPDIDSY
EECCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHH
VERLNTLLASGAGAARTVSTPLPDPASDALLASAMLQFETPSAAVVPESVPEPLAADLPA
HHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCC
SANPAAMPAAEPEAPFTPLRERRVAEGGERVLRVTAERLNGLLDMSSKSLVETQRLKPLL
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
AGMQRLKRLQSSSDRALEVLGASFGEEGPSADVQKALEDARSLLSQAQQVLVRHTAELDE
HHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGWQSAQRAQLLYDTALACRMRPFADVLNGQARMVRDLGRELGKQVRLQIEGEKTQVDRD
HCCCHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHEEEEECCCHHHHHHH
VLEKLDAPLTHLLRNAVDHGIESPEKRVASGKDPEGLIRLQASHQAGLLVVELSDDGGGV
HHHHHCCHHHHHHHHHHHHCCCCCHHHHCCCCCCCCEEEEEECCCCCEEEEEECCCCCCC
DLERVRQSIVDRKLSPAETAAQLSEEELLSFLFLPGFSMRDKVTQISGRGVGLDAVQHMV
CHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHH
RQMHGSVELQQWAGEGSRFRIEMPLTLSVVRSLVVEVGGEAYAFPLAHIERMRDLQPDDI
HHHHCCCCHHHHCCCCCEEEEECCHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCE
LQLEGRQHFWDEERHVGLVSASQLLNRPPAQKAGETLKVVVIRERDAVYGVAVERFIGER
EEECCCCCCCCCHHCCCCEEHHHHHCCCCCHHCCCEEEEEEEECCCCHHHHHHHHHHCCC
TLVVMPLDARLGKVQDVSAGALLDDGSVVLIIDVEDMLRSVEKLLNTGRLERIDRRARQA
EEEEEECCCCCCCCCCCCCCCEECCCCEEEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHH
DQVSRKRVLVVDDSLTVRELERKLLVSRGYEVSVAVDGMDGWNALRAEDFDLLITDIDMP
HHHHCCEEEEEECCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCEEEEEECCCC
RMDGIELVTLLRRDTRLQSLPVMVVSYKDREEDRRRGLDAGADYYLAKASFHDDALLDAV
CCCCHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHCCCCCCCCEEEEECCCCCHHHHHHH
VELIGDAQG
HHHHCCCCC
>Mature Secondary Structure 
TPDQMRDASLFELFTLEADAQTQVLSAGLLALERNPTQADQLEACMRAAHSLKGAARIV
CCCHHCCCHHHHEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEE
GVDFGVSVAHVMEDCLVSAQEGRLLLQAEHIDALLSGTDLLMRIATPGGDSVGQPDIDSY
EECCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHH
VERLNTLLASGAGAARTVSTPLPDPASDALLASAMLQFETPSAAVVPESVPEPLAADLPA
HHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCC
SANPAAMPAAEPEAPFTPLRERRVAEGGERVLRVTAERLNGLLDMSSKSLVETQRLKPLL
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
AGMQRLKRLQSSSDRALEVLGASFGEEGPSADVQKALEDARSLLSQAQQVLVRHTAELDE
HHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGWQSAQRAQLLYDTALACRMRPFADVLNGQARMVRDLGRELGKQVRLQIEGEKTQVDRD
HCCCHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHEEEEECCCHHHHHHH
VLEKLDAPLTHLLRNAVDHGIESPEKRVASGKDPEGLIRLQASHQAGLLVVELSDDGGGV
HHHHHCCHHHHHHHHHHHHCCCCCHHHHCCCCCCCCEEEEEECCCCCEEEEEECCCCCCC
DLERVRQSIVDRKLSPAETAAQLSEEELLSFLFLPGFSMRDKVTQISGRGVGLDAVQHMV
CHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHH
RQMHGSVELQQWAGEGSRFRIEMPLTLSVVRSLVVEVGGEAYAFPLAHIERMRDLQPDDI
HHHHCCCCHHHHCCCCCEEEEECCHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCE
LQLEGRQHFWDEERHVGLVSASQLLNRPPAQKAGETLKVVVIRERDAVYGVAVERFIGER
EEECCCCCCCCCHHCCCCEEHHHHHCCCCCHHCCCEEEEEEEECCCCHHHHHHHHHHCCC
TLVVMPLDARLGKVQDVSAGALLDDGSVVLIIDVEDMLRSVEKLLNTGRLERIDRRARQA
EEEEEECCCCCCCCCCCCCCCEECCCCEEEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHH
DQVSRKRVLVVDDSLTVRELERKLLVSRGYEVSVAVDGMDGWNALRAEDFDLLITDIDMP
HHHHCCEEEEEECCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCEEEEEECCCC
RMDGIELVTLLRRDTRLQSLPVMVVSYKDREEDRRRGLDAGADYYLAKASFHDDALLDAV
CCCCHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHCCCCCCCCEEEEECCCCCHHHHHHH
VELIGDAQG
HHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2165608; 2123853 [H]