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The map label for this gene is rio2 [H]

Identifier: 66043917

GI number: 66043917

Start: 738145

End: 739041

Strand: Direct

Name: rio2 [H]

Synonym: Psyr_0650

Alternate gene names: 66043917

Gene position: 738145-739041 (Clockwise)

Preceding gene: 66043916

Following gene: 66043918

Centisome position: 12.11

GC content: 62.21

Gene sequence:

>897_bases
ATGAAAACTCCTAAACGCATTGAACCCCTGATCGAAGACGGTCTGGTCGACGAGGTGCTGCGCCCGCTCATGAGTGGTAA
AGAGGCAGCTGTTTATGTGGTGCGTTGCGGCAATGAGCTGCGGTGTGCCAAGGTTTACAAGGAGGCTAACAAACGCAGTT
TCCGTCAGGCGGCCGAGTATCAGGAAGGTCGCAAGGTACGCAACAGCCGTCAGGCCCGCGCCATGGCCAAGGGCTCGAAG
TTCGGGCGCAAGGAAACCGAAGACGCTTGGCAGAATGCCGAAGTGGCTGCGCTGTTTCGTCTGGCCGGCGCAGGTGTCCG
GGTGCCCAAGCCGTACGACTTCCTGGAAGGCGTGCTGCTCATGGAACTGGTAGCTGACGAGTATGGCGATGCAGCGCCGC
GTCTGAACGACGTCGTGCTGGAGCCGGATCAGGCGCGCGAGTATCACGCATTCCTGATCGAGCAGATCGTGCTGATGCTG
TGTGCCGGTCTGGTGCACGGTGACCTGTCCGAGTTCAACGTGCTGCTGGCGCCGTCCGGCCCTGTCATCATCGACTTGCC
GCAAGCGGTCGATGCCGCGGGCAATAACCACGCGTTCAGCATGCTGGAGCGCGACGTCGGCAACATGGCGCTGTACTTCG
GCCGCTTCGCGCCGGAGCTCAGAAAGACCAAATACGCCAAGGAGATGTGGTCGTACTACGAGGCAGGCACCTTGTCGCCC
GCCACGGTGCTGACCGGTGAATTCGATGAGCCTGAGGACGAAGCCGATGTGGGCGGCGTACTGCGCGAAATCGAAGCCGC
CCGCCTCGACGAAGCCCGCCGCCAGGCAGCCCGTGCGGCAGACGATGCGCCACCGAGCAAATCCACCGAAGAGCCACCGC
CGCCGTGGATGCAGTAA

Upstream 100 bases:

>100_bases
CTTTCAATCCACAGGGGGTTACCCCTACTCGCTGGCGGAGGATTGCCGTATAACGGCAACAATCGCGTATCTGGCAACAA
AGGACCCACAATAAAAGCTG

Downstream 100 bases:

>100_bases
GGCCCTTTCGCGAGCAAGCTCGCTCCCACAGGGAGTGCGTGTGGCAGGCGCTCCGTCGATTGCATGCAGTAAGCCCCTTG
TGGGAGCGAGCTTGCTCGCG

Product: hypothetical protein

Products: NA

Alternate protein names: AfRio2 [H]

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MKTPKRIEPLIEDGLVDEVLRPLMSGKEAAVYVVRCGNELRCAKVYKEANKRSFRQAAEYQEGRKVRNSRQARAMAKGSK
FGRKETEDAWQNAEVAALFRLAGAGVRVPKPYDFLEGVLLMELVADEYGDAAPRLNDVVLEPDQAREYHAFLIEQIVLML
CAGLVHGDLSEFNVLLAPSGPVIIDLPQAVDAAGNNHAFSMLERDVGNMALYFGRFAPELRKTKYAKEMWSYYEAGTLSP
ATVLTGEFDEPEDEADVGGVLREIEAARLDEARRQAARAADDAPPSKSTEEPPPPWMQ

Sequences:

>Translated_298_residues
MKTPKRIEPLIEDGLVDEVLRPLMSGKEAAVYVVRCGNELRCAKVYKEANKRSFRQAAEYQEGRKVRNSRQARAMAKGSK
FGRKETEDAWQNAEVAALFRLAGAGVRVPKPYDFLEGVLLMELVADEYGDAAPRLNDVVLEPDQAREYHAFLIEQIVLML
CAGLVHGDLSEFNVLLAPSGPVIIDLPQAVDAAGNNHAFSMLERDVGNMALYFGRFAPELRKTKYAKEMWSYYEAGTLSP
ATVLTGEFDEPEDEADVGGVLREIEAARLDEARRQAARAADDAPPSKSTEEPPPPWMQ
>Mature_298_residues
MKTPKRIEPLIEDGLVDEVLRPLMSGKEAAVYVVRCGNELRCAKVYKEANKRSFRQAAEYQEGRKVRNSRQARAMAKGSK
FGRKETEDAWQNAEVAALFRLAGAGVRVPKPYDFLEGVLLMELVADEYGDAAPRLNDVVLEPDQAREYHAFLIEQIVLML
CAGLVHGDLSEFNVLLAPSGPVIIDLPQAVDAAGNNHAFSMLERDVGNMALYFGRFAPELRKTKYAKEMWSYYEAGTLSP
ATVLTGEFDEPEDEADVGGVLREIEAARLDEARRQAARAADDAPPSKSTEEPPPPWMQ

Specific function: Unknown

COG id: COG1718

COG function: function code TD; Serine/threonine protein kinase involved in cell cycle control

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI23510356, Length=210, Percent_Identity=31.9047619047619, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17556977, Length=222, Percent_Identity=30.6306306306306, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24662811, Length=238, Percent_Identity=30.2521008403361, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21356879, Length=238, Percent_Identity=30.2521008403361, Blast_Score=89, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011009
- InterPro:   IPR018934
- InterPro:   IPR015285
- InterPro:   IPR000687
- InterPro:   IPR008266 [H]

Pfam domain/function: PF01163 RIO1; PF09202 Rio2_N [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 33087; Mature: 33087

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS00109 PROTEIN_KINASE_TYR ; PS01245 RIO1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTPKRIEPLIEDGLVDEVLRPLMSGKEAAVYVVRCGNELRCAKVYKEANKRSFRQAAEY
CCCCHHHHHHHHCCHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
QEGRKVRNSRQARAMAKGSKFGRKETEDAWQNAEVAALFRLAGAGVRVPKPYDFLEGVLL
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCHHHHHHHHHHCCCCCCCCCHHHHHHHHH
MELVADEYGDAAPRLNDVVLEPDQAREYHAFLIEQIVLMLCAGLVHGDLSEFNVLLAPSG
HHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCEEEECCCC
PVIIDLPQAVDAAGNNHAFSMLERDVGNMALYFGRFAPELRKTKYAKEMWSYYEAGTLSP
CEEEECCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
ATVLTGEFDEPEDEADVGGVLREIEAARLDEARRQAARAADDAPPSKSTEEPPPPWMQ
HHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKTPKRIEPLIEDGLVDEVLRPLMSGKEAAVYVVRCGNELRCAKVYKEANKRSFRQAAEY
CCCCHHHHHHHHCCHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
QEGRKVRNSRQARAMAKGSKFGRKETEDAWQNAEVAALFRLAGAGVRVPKPYDFLEGVLL
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCHHHHHHHHHHCCCCCCCCCHHHHHHHHH
MELVADEYGDAAPRLNDVVLEPDQAREYHAFLIEQIVLMLCAGLVHGDLSEFNVLLAPSG
HHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCEEEECCCC
PVIIDLPQAVDAAGNNHAFSMLERDVGNMALYFGRFAPELRKTKYAKEMWSYYEAGTLSP
CEEEECCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
ATVLTGEFDEPEDEADVGGVLREIEAARLDEARRQAARAADDAPPSKSTEEPPPPWMQ
HHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]