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The map label for this gene is hflX [H]

Identifier: 66043840

GI number: 66043840

Start: 650892

End: 652193

Strand: Direct

Name: hflX [H]

Synonym: Psyr_0573

Alternate gene names: 66043840

Gene position: 650892-652193 (Clockwise)

Preceding gene: 66043839

Following gene: 66043841

Centisome position: 10.68

GC content: 59.37

Gene sequence:

>1302_bases
TTGTTCTTTGAGCGCCACAGTGGTGGTGAACGTGCAATTCTCGTTCATCTGGATGGTCAGGACCCTGAGGCGCGCGAAGA
TCCGCAGGAGTTTCAGGAATTGGCCATCTCGGCCGGTGCCGATACCGTTGCGTTTATCAACGTGCCGCGTCATCGGCCTT
CGGCCAAGTATCTGATCGGCTCTGGCAAGGTCGAGGAGCTTCGCGATCAGGTCAAGGCCGAGCAGGCCGATCTGGTCATC
TTCAATCACACCCTCACGCCCAGTCAGGAACGCAACCTCGAACGCGTTTTCGAGTGTCGTGTGCTTGATCGTACCGGTCT
GATTCTCGATATCTTTGCGCAGCGGGCGCGTACTCATGAGGGCAAGCTTCAGGTCGAACTGGCCCAGCTTGAACACATGA
GTACCCGTCTGGTCCGTGGCTGGACTCACCTTGAGCGACAGAAAGGTGGTATCGGCCTGCGCGGTCCGGGTGAAACCCAG
CTCGAAACCGACCGACGTCTTCTGCGGGTTCGCCTGCGGCAGATCAAGGGACGGCTGGAGAAGGTTCGCAGCCAGCGTGA
TCAGGCCCGTCGCGGGCGTCGTCGCGCGGATATTCCATCGGTTTCACTGGTGGGGTATACCAACGCCGGCAAATCCACCC
TGTTCAACTCGGTAACCGATTCGGATGTGTTCGCGGCGGACCAACTGTTCGCCACGCTCGATCCGACCTTGCGTCGTCTG
CAGCTCGATGACCTGGGTCCTATCGTGCTGGCCGATACCGTGGGCTTTATTCGCCACCTGCCGCACAAGCTGGTCGAGGC
CTTTCGCGCGACGCTTGAAGAATCGAGCAACTCCGATTTGCTGCTGCATGTGATCGACTCCCACGAGCCGGATCGCATGT
CGCAGATCGAGCAGGTGATGGCGGTGCTCGGCGAGATCGGAGCCGAGGGCTTGCCGATCCTCGAGGTCTATAACAAACTC
GATCTGCTTGAAGGCGTAGAGCCTCAGATACAGCGCGATGCCGACGGCAAACCGCAGCGTGTCTGGGTGTCTGCCCGTGA
TGGTCGAGGGCTTGATCTGCTCAAACAGGCTATCGCCGAATTGCTCGGCGACGATCTGTTTGTCGGCACGCTGCTTCTGC
CTCAAAGTCTTGCCCGGCTGCGTGCCCAGTTCTTTGAACTGGGTGCGGTGCAGAGCGAAACGCATGACGAGGAAGGTGCC
AGCGTGCTGGCCGTACGGCTGCCGCGCGTTGAACTCAATCGACTGGTGAGTCGCGAAGGATTGCAGCCGCTGGAGTTCAT
CGAGCAACACACTTTGCAATAA

Upstream 100 bases:

>100_bases
CATTTCCACCGTCGTACCGGTTCGTCCGATCCGCCTGCCAAGCGCTACAGACGCTGACGGCGCGGACGCCGAGCCAGGTA
ACGCCTGATAGGAGTCTGCC

Downstream 100 bases:

>100_bases
AAGCACGAGAAAGCCGTTGTACGGCTTTCCCGAGCATTCTGTAGCATTGGTCGGCGCGCCGCGGGCGCGTCTTTGCTTTA
TCAGATGGAGAGCGCTATGG

Product: GTP-binding protein, HSR1-related

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MFFERHSGGERAILVHLDGQDPEAREDPQEFQELAISAGADTVAFINVPRHRPSAKYLIGSGKVEELRDQVKAEQADLVI
FNHTLTPSQERNLERVFECRVLDRTGLILDIFAQRARTHEGKLQVELAQLEHMSTRLVRGWTHLERQKGGIGLRGPGETQ
LETDRRLLRVRLRQIKGRLEKVRSQRDQARRGRRRADIPSVSLVGYTNAGKSTLFNSVTDSDVFAADQLFATLDPTLRRL
QLDDLGPIVLADTVGFIRHLPHKLVEAFRATLEESSNSDLLLHVIDSHEPDRMSQIEQVMAVLGEIGAEGLPILEVYNKL
DLLEGVEPQIQRDADGKPQRVWVSARDGRGLDLLKQAIAELLGDDLFVGTLLLPQSLARLRAQFFELGAVQSETHDEEGA
SVLAVRLPRVELNRLVSREGLQPLEFIEQHTLQ

Sequences:

>Translated_433_residues
MFFERHSGGERAILVHLDGQDPEAREDPQEFQELAISAGADTVAFINVPRHRPSAKYLIGSGKVEELRDQVKAEQADLVI
FNHTLTPSQERNLERVFECRVLDRTGLILDIFAQRARTHEGKLQVELAQLEHMSTRLVRGWTHLERQKGGIGLRGPGETQ
LETDRRLLRVRLRQIKGRLEKVRSQRDQARRGRRRADIPSVSLVGYTNAGKSTLFNSVTDSDVFAADQLFATLDPTLRRL
QLDDLGPIVLADTVGFIRHLPHKLVEAFRATLEESSNSDLLLHVIDSHEPDRMSQIEQVMAVLGEIGAEGLPILEVYNKL
DLLEGVEPQIQRDADGKPQRVWVSARDGRGLDLLKQAIAELLGDDLFVGTLLLPQSLARLRAQFFELGAVQSETHDEEGA
SVLAVRLPRVELNRLVSREGLQPLEFIEQHTLQ
>Mature_433_residues
MFFERHSGGERAILVHLDGQDPEAREDPQEFQELAISAGADTVAFINVPRHRPSAKYLIGSGKVEELRDQVKAEQADLVI
FNHTLTPSQERNLERVFECRVLDRTGLILDIFAQRARTHEGKLQVELAQLEHMSTRLVRGWTHLERQKGGIGLRGPGETQ
LETDRRLLRVRLRQIKGRLEKVRSQRDQARRGRRRADIPSVSLVGYTNAGKSTLFNSVTDSDVFAADQLFATLDPTLRRL
QLDDLGPIVLADTVGFIRHLPHKLVEAFRATLEESSNSDLLLHVIDSHEPDRMSQIEQVMAVLGEIGAEGLPILEVYNKL
DLLEGVEPQIQRDADGKPQRVWVSARDGRGLDLLKQAIAELLGDDLFVGTLLLPQSLARLRAQFFELGAVQSETHDEEGA
SVLAVRLPRVELNRLVSREGLQPLEFIEQHTLQ

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133116, Length=224, Percent_Identity=39.2857142857143, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI310133118, Length=226, Percent_Identity=38.9380530973451, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI310124269, Length=206, Percent_Identity=40.2912621359223, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI310124267, Length=206, Percent_Identity=40.2912621359223, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI310124171, Length=206, Percent_Identity=40.2912621359223, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI310124169, Length=206, Percent_Identity=40.2912621359223, Blast_Score=131, Evalue=1e-30,
Organism=Escherichia coli, GI1790615, Length=418, Percent_Identity=58.6124401913876, Blast_Score=484, Evalue=1e-138,
Organism=Caenorhabditis elegans, GI17561038, Length=303, Percent_Identity=30.3630363036304, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24650079, Length=325, Percent_Identity=34.1538461538462, Blast_Score=132, Evalue=5e-31,
Organism=Drosophila melanogaster, GI20129375, Length=129, Percent_Identity=37.984496124031, Blast_Score=69, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 48727; Mature: 48727

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFERHSGGERAILVHLDGQDPEAREDPQEFQELAISAGADTVAFINVPRHRPSAKYLIG
CCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEC
SGKVEELRDQVKAEQADLVIFNHTLTPSQERNLERVFECRVLDRTGLILDIFAQRARTHE
CCCHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
GKLQVELAQLEHMSTRLVRGWTHLERQKGGIGLRGPGETQLETDRRLLRVRLRQIKGRLE
CCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
KVRSQRDQARRGRRRADIPSVSLVGYTNAGKSTLFNSVTDSDVFAADQLFATLDPTLRRL
HHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHCCCCCHHHHHHHHHHHHCHHHHHH
QLDDLGPIVLADTVGFIRHLPHKLVEAFRATLEESSNSDLLLHVIDSHEPDRMSQIEQVM
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHH
AVLGEIGAEGLPILEVYNKLDLLEGVEPQIQRDADGKPQRVWVSARDGRGLDLLKQAIAE
HHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHH
LLGDDLFVGTLLLPQSLARLRAQFFELGAVQSETHDEEGASVLAVRLPRVELNRLVSREG
HHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHCC
LQPLEFIEQHTLQ
CCHHHHHHHHCCC
>Mature Secondary Structure
MFFERHSGGERAILVHLDGQDPEAREDPQEFQELAISAGADTVAFINVPRHRPSAKYLIG
CCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEC
SGKVEELRDQVKAEQADLVIFNHTLTPSQERNLERVFECRVLDRTGLILDIFAQRARTHE
CCCHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
GKLQVELAQLEHMSTRLVRGWTHLERQKGGIGLRGPGETQLETDRRLLRVRLRQIKGRLE
CCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
KVRSQRDQARRGRRRADIPSVSLVGYTNAGKSTLFNSVTDSDVFAADQLFATLDPTLRRL
HHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHCCCCCHHHHHHHHHHHHCHHHHHH
QLDDLGPIVLADTVGFIRHLPHKLVEAFRATLEESSNSDLLLHVIDSHEPDRMSQIEQVM
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHH
AVLGEIGAEGLPILEVYNKLDLLEGVEPQIQRDADGKPQRVWVSARDGRGLDLLKQAIAE
HHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHH
LLGDDLFVGTLLLPQSLARLRAQFFELGAVQSETHDEEGASVLAVRLPRVELNRLVSREG
HHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHCC
LQPLEFIEQHTLQ
CCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]