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The map label for this gene is ccpA1 [H]

Identifier: 62390251

GI number: 62390251

Start: 1433039

End: 1434079

Strand: Reverse

Name: ccpA1 [H]

Synonym: cg1547

Alternate gene names: 62390251

Gene position: 1434079-1433039 (Counterclockwise)

Preceding gene: 62390256

Following gene: 62390250

Centisome position: 43.69

GC content: 49.86

Gene sequence:

>1041_bases
ATGGCGACGGAAAAATTCCGACCGACTCTTAAAGATGTCGCTCGTCAAGCAGGTGTCTCCATCGCCACAGCATCACGAGC
ACTAGCGGATAATCCGGCGGTTGCTGCATCGACTCGTGAAAGAATCCAACAATTAGCCTCTGATCTGGGTTACCGGGCCA
ATGCTCAAGCTCGTGCGCTTCGCAGTTCTCGCAGCAACACCATTGGTGTGATTGTTCCCAGTTTGATTAACCATTACTTC
GCCGCAATGGTTACTGAAATTCAAAGCACCGCCAGCAAAGCTGGACTTGCCACGATTATCACCAACAGCAATGAAGATGC
GACCACTATGTCTGGGTCTTTGGAGTTTCTCACCTCGCATGGTGTCGATGGAATCATCTGCGTACCTAATGAGGAATGCG
CGAATCAACTAGAGGACTTGCAGAAGCAAGGAATGCCAGTGGTGTTGGTTGACCGAGAGCTTCCAGGAGACTCCACCATC
CCAACGGCGACCTCTAACCCCCAACCAGGAATCGCCGCAGCAGTAGAACTCCTGGCTCACAACAACGCGTTGCCGATTGG
TTACCTCTCAGGTCCCATGGACACCTCAACAGGTAGAGAGCGATTAGAGGATTTCAAAGCAGCCTGCGCCAACTCCAAAA
TTGGCGAACAGCTCGTTTTTCTGGGTGGGTACGAACAAAGCGTTGGATTTGAAGGCGCTACGAAATTGCTCGATCAAGGA
GCTAAAACTCTTTTTGCCGGCGATTCTATGATGACGATCGGTGTCATTGAAGCCTGCCATAAGGCTGGTTTGGTTATCGG
CAAGGATGTCAGCGTGATTGGTTTTGATACACATCCGCTTTTTGCCCTGCAACCTCATCCGTTGACAGTGATTGATCAAA
ATGTAGAACAACTAGCCCAACGAGCAGTGTCTATCCTCACCGAATTAATTGCAGGCACGGTACCTAGCGTGACGAAAACT
ACGATCCCCACTGCCCTTATTCATCGTGAATCAATCATCAACTCCACTTTAAGGAAGAAGGATGGACTCCCCAATGAGTA
A

Upstream 100 bases:

>100_bases
CCAACATCGCCTTGCACGTAATAGGTTAAAACACAAGTGAATGTAATCGTTTGCAGCAATCGATTACATAAAGGTAGATA
ATGAGATAAAGCGAGGCGCT

Downstream 100 bases:

>100_bases
CTCAACCGGTACCGACATTGTCGTTGTCGGATCCATCAATGCCGATCTCACCGCAAAAGTTCAACGCCACCCTGAACCTG
GAGAAACCCTCCTGGGTAGC

Product: LacI family transcriptional regulator

Products: NA

Alternate protein names: Catabolite control protein [H]

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MATEKFRPTLKDVARQAGVSIATASRALADNPAVAASTRERIQQLASDLGYRANAQARALRSSRSNTIGVIVPSLINHYF
AAMVTEIQSTASKAGLATIITNSNEDATTMSGSLEFLTSHGVDGIICVPNEECANQLEDLQKQGMPVVLVDRELPGDSTI
PTATSNPQPGIAAAVELLAHNNALPIGYLSGPMDTSTGRERLEDFKAACANSKIGEQLVFLGGYEQSVGFEGATKLLDQG
AKTLFAGDSMMTIGVIEACHKAGLVIGKDVSVIGFDTHPLFALQPHPLTVIDQNVEQLAQRAVSILTELIAGTVPSVTKT
TIPTALIHRESIINSTLRKKDGLPNE

Sequences:

>Translated_346_residues
MATEKFRPTLKDVARQAGVSIATASRALADNPAVAASTRERIQQLASDLGYRANAQARALRSSRSNTIGVIVPSLINHYF
AAMVTEIQSTASKAGLATIITNSNEDATTMSGSLEFLTSHGVDGIICVPNEECANQLEDLQKQGMPVVLVDRELPGDSTI
PTATSNPQPGIAAAVELLAHNNALPIGYLSGPMDTSTGRERLEDFKAACANSKIGEQLVFLGGYEQSVGFEGATKLLDQG
AKTLFAGDSMMTIGVIEACHKAGLVIGKDVSVIGFDTHPLFALQPHPLTVIDQNVEQLAQRAVSILTELIAGTVPSVTKT
TIPTALIHRESIINSTLRKKDGLPNE
>Mature_345_residues
ATEKFRPTLKDVARQAGVSIATASRALADNPAVAASTRERIQQLASDLGYRANAQARALRSSRSNTIGVIVPSLINHYFA
AMVTEIQSTASKAGLATIITNSNEDATTMSGSLEFLTSHGVDGIICVPNEECANQLEDLQKQGMPVVLVDRELPGDSTIP
TATSNPQPGIAAAVELLAHNNALPIGYLSGPMDTSTGRERLEDFKAACANSKIGEQLVFLGGYEQSVGFEGATKLLDQGA
KTLFAGDSMMTIGVIEACHKAGLVIGKDVSVIGFDTHPLFALQPHPLTVIDQNVEQLAQRAVSILTELIAGTVPSVTKTT
IPTALIHRESIINSTLRKKDGLPNE

Specific function: Transcriptional regulator involved in both the repression of carbohydrate utilization genes such as the alpha- amylase (amyE) and the acetyl-coenzyme A synthetase (acsA); and in the positive regulation of genes involved in excretion of excess carbon such

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789068, Length=335, Percent_Identity=29.8507462686567, Blast_Score=138, Evalue=7e-34,
Organism=Escherichia coli, GI1790194, Length=307, Percent_Identity=28.3387622149837, Blast_Score=131, Evalue=6e-32,
Organism=Escherichia coli, GI1788474, Length=329, Percent_Identity=28.8753799392097, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1787948, Length=336, Percent_Identity=26.1904761904762, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1790369, Length=308, Percent_Identity=26.2987012987013, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1789202, Length=276, Percent_Identity=29.3478260869565, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1787580, Length=332, Percent_Identity=27.4096385542169, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1786540, Length=331, Percent_Identity=26.2839879154079, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI48994940, Length=283, Percent_Identity=25.7950530035336, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1790715, Length=142, Percent_Identity=32.3943661971831, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787906, Length=208, Percent_Identity=27.4038461538462, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1786268, Length=309, Percent_Identity=23.3009708737864, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1790689, Length=249, Percent_Identity=23.6947791164659, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006377
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36569; Mature: 36438

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATEKFRPTLKDVARQAGVSIATASRALADNPAVAASTRERIQQLASDLGYRANAQARAL
CCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHH
RSSRSNTIGVIVPSLINHYFAAMVTEIQSTASKAGLATIITNSNEDATTMSGSLEFLTSH
HHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHCCCHHHHHHC
GVDGIICVPNEECANQLEDLQKQGMPVVLVDRELPGDSTIPTATSNPQPGIAAAVELLAH
CCCEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHC
NNALPIGYLSGPMDTSTGRERLEDFKAACANSKIGEQLVFLGGYEQSVGFEGATKLLDQG
CCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHCCCHHHHHHHHCC
AKTLFAGDSMMTIGVIEACHKAGLVIGKDVSVIGFDTHPLFALQPHPLTVIDQNVEQLAQ
CCEEECCCCHHHHHHHHHHHHCCEEEECCEEEEEECCCCEEEECCCCCHHHHHHHHHHHH
RAVSILTELIAGTVPSVTKTTIPTALIHRESIINSTLRKKDGLPNE
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
ATEKFRPTLKDVARQAGVSIATASRALADNPAVAASTRERIQQLASDLGYRANAQARAL
CCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHH
RSSRSNTIGVIVPSLINHYFAAMVTEIQSTASKAGLATIITNSNEDATTMSGSLEFLTSH
HHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHCCCHHHHHHC
GVDGIICVPNEECANQLEDLQKQGMPVVLVDRELPGDSTIPTATSNPQPGIAAAVELLAH
CCCEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHC
NNALPIGYLSGPMDTSTGRERLEDFKAACANSKIGEQLVFLGGYEQSVGFEGATKLLDQG
CCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHCCCHHHHHHHHCC
AKTLFAGDSMMTIGVIEACHKAGLVIGKDVSVIGFDTHPLFALQPHPLTVIDQNVEQLAQ
CCEEECCCCHHHHHHHHHHHHCCEEEECCEEEEEECCCCEEEECCCCCHHHHHHHHHHHH
RAVSILTELIAGTVPSVTKTTIPTALIHRESIINSTLRKKDGLPNE
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8200532 [H]