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The map label for this gene is benK3 [H]

Identifier: 62389965

GI number: 62389965

Start: 1124999

End: 1126294

Strand: Reverse

Name: benK3 [H]

Synonym: cg1225

Alternate gene names: 62389965

Gene position: 1126294-1124999 (Counterclockwise)

Preceding gene: 62389966

Following gene: 62389963

Centisome position: 34.31

GC content: 56.94

Gene sequence:

>1296_bases
GTGTCAACGACCACCCCAACCCGCGCAACCAAAAGTGTCGGAACAGTTCTCGCACTCCTGTGGTTCGCAATTGTCCTCGA
CGGCTTTGACCTAGTCGTCCTGGGTGCAACAATCCCGTCCATGCTGGAGGATCCCGCGTGGGATCTCACTGCTGGACAGG
CCACACAGATTTCCACCATCGGCCTCGTCGGCATGACCATTGGCGCACTGACCATCGGTTTCTTAACGGACCGTCTGGGT
CGACGCCGTGTCATGCTGTTCTCTGTGGCAGTATTTTCTGTATTCACTCTCCTGCTGGCATTCACCACCAACGTCCAGCT
CTTCAGCCTGTGGCGTTTCCTCGCAGGTGTTGGCCTTGGTGGAGCACTCCCCACCGCAATTGCCATGGTGACCGAGTTCC
GCCCCGGCACCAAAGCGGGCTCTGCATCCACCACCTTGATGACCGGCTACCACGTCGGCGCAGTAGCAACCGCCTTCCTT
GGCCTCTTCCTTATCGACGGCTTTGGTTGGCACTCCATGTTCATCGCAGGTGCCGTACCAGGACTGATCCTGCTACCACT
GCTGTACTTCTTCCTTCCAGAATCCCCGCAGTACCTCAAAATCTCCGGCAAGTTGGATGAGGCGCAGGCAGTTGCAGCAT
CTTATGGACTTTCCCTGGATGATGATCTTGATCGCGAACACGAAGAAGAACTCGGCGAGTCCTCCTCACTTTCCTCCCTG
TTCAAGCCCTCGTTCCGCCGCAACACCCTGGCGATTTGGGGCACCTCATTCATGGGACTCCTCCTGGTCTACGGCCTGAA
CACATGGCTGCCACAAATCATGCGCCAAGCAGACTACGACATGGGTAACTCGCTTGGATTCCTCATGGTGCTCAACATCG
GCGCAGTGATCGGCCTTTATATTGCAGGGCGAATTGCCGATAAGAACTCCCCTCGCAAAACAGCACTCGTATGGTTCGTG
TTCTCTGCATTTTCCCTCGCGTTGCTTGCTGTCCGGATGCCACTGATCGGTCTGTATGGCATCGTGCTGCTCACCGGCAT
CTTTGTGTTCAGCTCCCAGGTACTCATCTACGCCTTCGTTGGTGAGAATCACCCTGCCAAGATGCGCGCAACCGCCATGG
GATTCTCCGCAGGAATTGGTCGCCTCGGCGCCATCTCTGGCCCGTTGCTTGGTGGTCTGCTTGTCAGTGCCAACCTTGCT
TACCCATGGGGCTTCTTCGCTTTCGCTGGCGTCGGTCTGCTGGGCGCGCTGATTTTCTCCGCATCGAAGACTCTGAGGCA
TCGCGAGAACGCTTAA

Upstream 100 bases:

>100_bases
CGCTGAATTGCGCTCCGTCCTAGAATCCCAATCCGGCCAACGCTACCTCGCAGAGCAGTACGTTGGGCGCGACCTACCAC
GCTTCGAGGTATAAACGCTC

Downstream 100 bases:

>100_bases
GTTTTAACACTGAAAAAGGTCGTTGCATTTTCTTGAGGTTGAAAATGCAACGATCTTTTTATGCTTTTAGTCTGAGGAAA
TATTCCACATCACACCAAAT

Product: benzoate transport transmembrane protein

Products: Proton [Cytoplasm]; 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 430

Protein sequence:

>431_residues
MSTTTPTRATKSVGTVLALLWFAIVLDGFDLVVLGATIPSMLEDPAWDLTAGQATQISTIGLVGMTIGALTIGFLTDRLG
RRRVMLFSVAVFSVFTLLLAFTTNVQLFSLWRFLAGVGLGGALPTAIAMVTEFRPGTKAGSASTTLMTGYHVGAVATAFL
GLFLIDGFGWHSMFIAGAVPGLILLPLLYFFLPESPQYLKISGKLDEAQAVAASYGLSLDDDLDREHEEELGESSSLSSL
FKPSFRRNTLAIWGTSFMGLLLVYGLNTWLPQIMRQADYDMGNSLGFLMVLNIGAVIGLYIAGRIADKNSPRKTALVWFV
FSAFSLALLAVRMPLIGLYGIVLLTGIFVFSSQVLIYAFVGENHPAKMRATAMGFSAGIGRLGAISGPLLGGLLVSANLA
YPWGFFAFAGVGLLGALIFSASKTLRHRENA

Sequences:

>Translated_431_residues
MSTTTPTRATKSVGTVLALLWFAIVLDGFDLVVLGATIPSMLEDPAWDLTAGQATQISTIGLVGMTIGALTIGFLTDRLG
RRRVMLFSVAVFSVFTLLLAFTTNVQLFSLWRFLAGVGLGGALPTAIAMVTEFRPGTKAGSASTTLMTGYHVGAVATAFL
GLFLIDGFGWHSMFIAGAVPGLILLPLLYFFLPESPQYLKISGKLDEAQAVAASYGLSLDDDLDREHEEELGESSSLSSL
FKPSFRRNTLAIWGTSFMGLLLVYGLNTWLPQIMRQADYDMGNSLGFLMVLNIGAVIGLYIAGRIADKNSPRKTALVWFV
FSAFSLALLAVRMPLIGLYGIVLLTGIFVFSSQVLIYAFVGENHPAKMRATAMGFSAGIGRLGAISGPLLGGLLVSANLA
YPWGFFAFAGVGLLGALIFSASKTLRHRENA
>Mature_430_residues
STTTPTRATKSVGTVLALLWFAIVLDGFDLVVLGATIPSMLEDPAWDLTAGQATQISTIGLVGMTIGALTIGFLTDRLGR
RRVMLFSVAVFSVFTLLLAFTTNVQLFSLWRFLAGVGLGGALPTAIAMVTEFRPGTKAGSASTTLMTGYHVGAVATAFLG
LFLIDGFGWHSMFIAGAVPGLILLPLLYFFLPESPQYLKISGKLDEAQAVAASYGLSLDDDLDREHEEELGESSSLSSLF
KPSFRRNTLAIWGTSFMGLLLVYGLNTWLPQIMRQADYDMGNSLGFLMVLNIGAVIGLYIAGRIADKNSPRKTALVWFVF
SAFSLALLAVRMPLIGLYGIVLLTGIFVFSSQVLIYAFVGENHPAKMRATAMGFSAGIGRLGAISGPLLGGLLVSANLAY
PWGFFAFAGVGLLGALIFSASKTLRHRENA

Specific function: Probable uptake of benzoate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI24308167, Length=424, Percent_Identity=24.0566037735849, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI216548223, Length=311, Percent_Identity=27.9742765273312, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI7662270, Length=199, Percent_Identity=31.6582914572864, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI166064021, Length=350, Percent_Identity=26.2857142857143, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI262399383, Length=162, Percent_Identity=33.9506172839506, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI213021148, Length=412, Percent_Identity=22.5728155339806, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI24497490, Length=360, Percent_Identity=24.1666666666667, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI24497476, Length=398, Percent_Identity=25.3768844221106, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI20070188, Length=398, Percent_Identity=25.3768844221106, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI31542327, Length=407, Percent_Identity=26.2899262899263, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI73695465, Length=163, Percent_Identity=30.6748466257669, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI11415038, Length=261, Percent_Identity=29.1187739463602, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI4507005, Length=359, Percent_Identity=23.6768802228412, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI166197673, Length=374, Percent_Identity=23.5294117647059, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI87081723, Length=344, Percent_Identity=31.1046511627907, Blast_Score=138, Evalue=7e-34,
Organism=Escherichia coli, GI1788068, Length=393, Percent_Identity=25.4452926208651, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1786229, Length=379, Percent_Identity=26.1213720316623, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788074, Length=410, Percent_Identity=26.5853658536585, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI87082404, Length=376, Percent_Identity=22.8723404255319, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI87082231, Length=444, Percent_Identity=22.972972972973, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87082159, Length=383, Percent_Identity=26.3707571801567, Blast_Score=81, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI32564663, Length=422, Percent_Identity=23.2227488151659, Blast_Score=101, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI71986689, Length=227, Percent_Identity=28.6343612334802, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193202825, Length=227, Percent_Identity=28.6343612334802, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI19922874, Length=431, Percent_Identity=20.8816705336427, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24640198, Length=301, Percent_Identity=25.5813953488372, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24640196, Length=301, Percent_Identity=25.5813953488372, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24640200, Length=301, Percent_Identity=25.5813953488372, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24648211, Length=232, Percent_Identity=27.1551724137931, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24649618, Length=374, Percent_Identity=23.7967914438503, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI20130083, Length=307, Percent_Identity=28.3387622149837, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI19922616, Length=418, Percent_Identity=21.5311004784689, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24649616, Length=377, Percent_Identity=23.8726790450928, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI161077756, Length=420, Percent_Identity=22.3809523809524, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004746
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46012; Mature: 45880

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTTTPTRATKSVGTVLALLWFAIVLDGFDLVVLGATIPSMLEDPAWDLTAGQATQISTI
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHEEEHHHHHHHHCCCCCCCCCCCCCHHHHH
GLVGMTIGALTIGFLTDRLGRRRVMLFSVAVFSVFTLLLAFTTNVQLFSLWRFLAGVGLG
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC
GALPTAIAMVTEFRPGTKAGSASTTLMTGYHVGAVATAFLGLFLIDGFGWHSMFIAGAVP
HHHHHHHHHHHHCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
GLILLPLLYFFLPESPQYLKISGKLDEAQAVAASYGLSLDDDLDREHEEELGESSSLSSL
HHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCHHHH
FKPSFRRNTLAIWGTSFMGLLLVYGLNTWLPQIMRQADYDMGNSLGFLMVLNIGAVIGLY
HCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
IAGRIADKNSPRKTALVWFVFSAFSLALLAVRMPLIGLYGIVLLTGIFVFSSQVLIYAFV
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEE
GENHPAKMRATAMGFSAGIGRLGAISGPLLGGLLVSANLAYPWGFFAFAGVGLLGALIFS
CCCCCCHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
ASKTLRHRENA
HHHHHHHCCCC
>Mature Secondary Structure 
STTTPTRATKSVGTVLALLWFAIVLDGFDLVVLGATIPSMLEDPAWDLTAGQATQISTI
CCCCCCHHHHHHHHHHHHHHHHHHHCCCHHEEEHHHHHHHHCCCCCCCCCCCCCHHHHH
GLVGMTIGALTIGFLTDRLGRRRVMLFSVAVFSVFTLLLAFTTNVQLFSLWRFLAGVGLG
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC
GALPTAIAMVTEFRPGTKAGSASTTLMTGYHVGAVATAFLGLFLIDGFGWHSMFIAGAVP
HHHHHHHHHHHHCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
GLILLPLLYFFLPESPQYLKISGKLDEAQAVAASYGLSLDDDLDREHEEELGESSSLSSL
HHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCHHHH
FKPSFRRNTLAIWGTSFMGLLLVYGLNTWLPQIMRQADYDMGNSLGFLMVLNIGAVIGLY
HCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
IAGRIADKNSPRKTALVWFVFSAFSLALLAVRMPLIGLYGIVLLTGIFVFSSQVLIYAFV
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEE
GENHPAKMRATAMGFSAGIGRLGAISGPLLGGLLVSANLAYPWGFFAFAGVGLLGALIFS
CCCCCCHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
ASKTLRHRENA
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; 3-(3-hydroxyphenyl)propionate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + 3-(3-hydroxyphenyl)propionate [Periplasm] = Proton [Cytoplasm] + 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9294456 [H]