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The map label for this gene is nahR [H]

Identifier: 59712586

GI number: 59712586

Start: 2211249

End: 2212178

Strand: Direct

Name: nahR [H]

Synonym: VF_1979

Alternate gene names: 59712586

Gene position: 2211249-2212178 (Clockwise)

Preceding gene: 59712583

Following gene: 59712587

Centisome position: 76.31

GC content: 34.73

Gene sequence:

>930_bases
ATGGCAAAAGATCTATTCGCAACATTGGATTTAAATTTGCTGAGAACATTTTTAATTCTTTCTCAAGAATTGAATATGCG
AAAAGCCTCTGAACGCTTATTTGTCTCTCAACCGGCAATTAGCCAAGCATTGCAAAAATTGCGAAATCACTTCAATGATG
AGCTGTTTATTAAAGTTCGCCATGGCCTTAAACCAACCCCCTTTGCCGAAGAATTAGCGGAAAATATCCAACCTTATTTA
GATGGTCTATCGTCGGTATTAAATGCATCACAAGAATTCCAACCAGAAAATTTAAATAAGACATTGAAAATTGCTTTAGC
ACCTCAAGTATTAACCTGTTTATCTGGTGCTTTATTTCATGAGGTCAGAGAAAAAGCACCTAATGTTGATTTACAACTGG
TCAATTGGTCAGAATCTACTTTTGATGATTTGAGCAAGGGTAAATTAGATATCGCAATCAGTTACGAATATGACAAATTT
CCTAAAGAGTTACTTTCAAAAAGTCTAATAACAATAACTGGATGCGTCATTGTTAGAAAAGATCACCCAATAGAAAAAAT
GATTGCAACACCATATGACTTTGAAGGATATGAACTGGCTTCTTTAATTATTCCTGGTTGGAACGATAACAAAAGTTTAG
CAAGTGAGCTTCTAACCAAGATGAATATTGAACATAAGATAGGGTTTCGTTCAGAGCTACCAATGGCGCTAGTTGATGTT
GTTCAGCATACAGACATGTATTTCCCTTCCACCTCCTTATTTCCAATTCATCAATACTCAGGTTTAAGACGAATCGATTT
ATCTCTTGATGATGTGCCATTAAATTACCCAATCTATAGCTATTTCCACCAAAGACATAAAAAAAATGCACTGCACGCTT
GGGTTAATCAGCTTATTACGAATTTATTATCAGAAGCAAATATCAAATAA

Upstream 100 bases:

>100_bases
GATAGTAATAAACTTACTCTTGGTCTTAAGTAATAATATAAGTACTATAGAAAGAGACTTAAAAAAGCACACCAAATTAT
TTATAAGGAAATAAGTAAAT

Downstream 100 bases:

>100_bases
GTATGCCTTATGAGCTACATAATGAAAGATGATTGGTTCACTATCATAAGTATTTATATTATCTAAACCAGTCAACAGGA
ATGATATTCAAGCGTATTAC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MAKDLFATLDLNLLRTFLILSQELNMRKASERLFVSQPAISQALQKLRNHFNDELFIKVRHGLKPTPFAEELAENIQPYL
DGLSSVLNASQEFQPENLNKTLKIALAPQVLTCLSGALFHEVREKAPNVDLQLVNWSESTFDDLSKGKLDIAISYEYDKF
PKELLSKSLITITGCVIVRKDHPIEKMIATPYDFEGYELASLIIPGWNDNKSLASELLTKMNIEHKIGFRSELPMALVDV
VQHTDMYFPSTSLFPIHQYSGLRRIDLSLDDVPLNYPIYSYFHQRHKKNALHAWVNQLITNLLSEANIK

Sequences:

>Translated_309_residues
MAKDLFATLDLNLLRTFLILSQELNMRKASERLFVSQPAISQALQKLRNHFNDELFIKVRHGLKPTPFAEELAENIQPYL
DGLSSVLNASQEFQPENLNKTLKIALAPQVLTCLSGALFHEVREKAPNVDLQLVNWSESTFDDLSKGKLDIAISYEYDKF
PKELLSKSLITITGCVIVRKDHPIEKMIATPYDFEGYELASLIIPGWNDNKSLASELLTKMNIEHKIGFRSELPMALVDV
VQHTDMYFPSTSLFPIHQYSGLRRIDLSLDDVPLNYPIYSYFHQRHKKNALHAWVNQLITNLLSEANIK
>Mature_308_residues
AKDLFATLDLNLLRTFLILSQELNMRKASERLFVSQPAISQALQKLRNHFNDELFIKVRHGLKPTPFAEELAENIQPYLD
GLSSVLNASQEFQPENLNKTLKIALAPQVLTCLSGALFHEVREKAPNVDLQLVNWSESTFDDLSKGKLDIAISYEYDKFP
KELLSKSLITITGCVIVRKDHPIEKMIATPYDFEGYELASLIIPGWNDNKSLASELLTKMNIEHKIGFRSELPMALVDVV
QHTDMYFPSTSLFPIHQYSGLRRIDLSLDDVPLNYPIYSYFHQRHKKNALHAWVNQLITNLLSEANIK

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790147, Length=304, Percent_Identity=24.6710526315789, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1786820, Length=304, Percent_Identity=25.3289473684211, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87081684, Length=247, Percent_Identity=24.6963562753036, Blast_Score=79, Evalue=4e-16,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35312; Mature: 35181

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKDLFATLDLNLLRTFLILSQELNMRKASERLFVSQPAISQALQKLRNHFNDELFIKVR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEEE
HGLKPTPFAEELAENIQPYLDGLSSVLNASQEFQPENLNKTLKIALAPQVLTCLSGALFH
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHH
EVREKAPNVDLQLVNWSESTFDDLSKGKLDIAISYEYDKFPKELLSKSLITITGCVIVRK
HHHHHCCCCEEEEECCCCHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHHHHEEEEEEC
DHPIEKMIATPYDFEGYELASLIIPGWNDNKSLASELLTKMNIEHKIGFRSELPMALVDV
CCCHHHHHCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCHHCCCCCCCCCHHHHHH
VQHTDMYFPSTSLFPIHQYSGLRRIDLSLDDVPLNYPIYSYFHQRHKKNALHAWVNQLIT
HHHCCCCCCCCCCCEEHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHH
NLLSEANIK
HHHHHCCCC
>Mature Secondary Structure 
AKDLFATLDLNLLRTFLILSQELNMRKASERLFVSQPAISQALQKLRNHFNDELFIKVR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEEE
HGLKPTPFAEELAENIQPYLDGLSSVLNASQEFQPENLNKTLKIALAPQVLTCLSGALFH
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHH
EVREKAPNVDLQLVNWSESTFDDLSKGKLDIAISYEYDKFPKELLSKSLITITGCVIVRK
HHHHHCCCCEEEEECCCCHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHHHHEEEEEEC
DHPIEKMIATPYDFEGYELASLIIPGWNDNKSLASELLTKMNIEHKIGFRSELPMALVDV
CCCHHHHHCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCHHCCCCCCCCCHHHHHH
VQHTDMYFPSTSLFPIHQYSGLRRIDLSLDDVPLNYPIYSYFHQRHKKNALHAWVNQLIT
HHHCCCCCCCCCCCEEHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHH
NLLSEANIK
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]