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The map label for this gene is cutC [H]

Identifier: 59712583

GI number: 59712583

Start: 2209087

End: 2209830

Strand: Direct

Name: cutC [H]

Synonym: VF_1976

Alternate gene names: 59712583

Gene position: 2209087-2209830 (Clockwise)

Preceding gene: 59712582

Following gene: 59712586

Centisome position: 76.24

GC content: 39.78

Gene sequence:

>744_bases
ATGTCTATTCAAATTGAAGTCTGTATCGACAACCTAGAATCTCTACATAACGCAATAGCAGGTGGAGCAGATCGCATTGA
ACTTTGCTCTTCTTTAGCTCTTGGTGGCTTAACTCCAAGCTTTGGCTTTATGAAAAAAGCCGCTGAAATCTCCCCTATTC
CTGTCTATGCAATGATAAGACCTCGCCAAGGTGATTTCTTATATGATAACGATGATATATCAGCCATGATTTCTGATATC
CAAGCGGCTAAATTAGCAGGCTTACAGGGCGTTGTATTTGGCGTATTAAAAGCCAATGGCGACATTGACATGCCACTTTC
AGCTCGTTTAATGAAAATAGCTAACGATAATGATTTAGGCGTGACTTTTCATCGTGCTATAGACCAATGTTCTAACTATA
AAAAAGCGATTGAGAATATTGCAGAACTTGGCTGTGAACGCATTCTAACCTCAGGGTTAGCAGCGAATGCCTATGATGGG
ATAAATGTACTAGCAGATATGGTTAAACTCGCCAATGGACGTTTTGATATATTAGCTGGTGCAGGTGTCACCGCAGAAAA
TGCAAAAGAAATAATAGAGAAAACAGGTGTGAAAGAGATTCACTTATCAGGTAAGTCCACACGACCAAGTAAAATGAAAC
TGGTTTTAGATGGAGTGAAAATGGGTGCCGGTGATTTGGATGATTTTATTGTCCCAGTGACGGACTCTAAAAAAATTGAT
GCCGTTAAGCAGCGCATAAAATAA

Upstream 100 bases:

>100_bases
CTTATTAACTCTAATATAGATTCAATTCTGACGCCCTCTTCACACTACTTTCTTGGTTTATCCCTTACACTACAAGTATC
TTTTTTTATATTTTTATATC

Downstream 100 bases:

>100_bases
AAATAAAAAAGCCAGAGTACAAAAACTCTGGCTTTTATAAGTAAAATAACGAGTAATTATTTAGCTAATTGAACTGTATT
TACGTCAATTGTTGTCTCAG

Product: copper homeostasis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MSIQIEVCIDNLESLHNAIAGGADRIELCSSLALGGLTPSFGFMKKAAEISPIPVYAMIRPRQGDFLYDNDDISAMISDI
QAAKLAGLQGVVFGVLKANGDIDMPLSARLMKIANDNDLGVTFHRAIDQCSNYKKAIENIAELGCERILTSGLAANAYDG
INVLADMVKLANGRFDILAGAGVTAENAKEIIEKTGVKEIHLSGKSTRPSKMKLVLDGVKMGAGDLDDFIVPVTDSKKID
AVKQRIK

Sequences:

>Translated_247_residues
MSIQIEVCIDNLESLHNAIAGGADRIELCSSLALGGLTPSFGFMKKAAEISPIPVYAMIRPRQGDFLYDNDDISAMISDI
QAAKLAGLQGVVFGVLKANGDIDMPLSARLMKIANDNDLGVTFHRAIDQCSNYKKAIENIAELGCERILTSGLAANAYDG
INVLADMVKLANGRFDILAGAGVTAENAKEIIEKTGVKEIHLSGKSTRPSKMKLVLDGVKMGAGDLDDFIVPVTDSKKID
AVKQRIK
>Mature_246_residues
SIQIEVCIDNLESLHNAIAGGADRIELCSSLALGGLTPSFGFMKKAAEISPIPVYAMIRPRQGDFLYDNDDISAMISDIQ
AAKLAGLQGVVFGVLKANGDIDMPLSARLMKIANDNDLGVTFHRAIDQCSNYKKAIENIAELGCERILTSGLAANAYDGI
NVLADMVKLANGRFDILAGAGVTAENAKEIIEKTGVKEIHLSGKSTRPSKMKLVLDGVKMGAGDLDDFIVPVTDSKKIDA
VKQRIK

Specific function: Involved in copper homeostasis [H]

COG id: COG3142

COG function: function code P; Uncharacterized protein involved in copper resistance

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CutC family [H]

Homologues:

Organism=Homo sapiens, GI148596990, Length=236, Percent_Identity=44.4915254237288, Blast_Score=196, Evalue=1e-50,
Organism=Escherichia coli, GI87081995, Length=240, Percent_Identity=36.25, Blast_Score=160, Evalue=6e-41,
Organism=Caenorhabditis elegans, GI17556905, Length=224, Percent_Identity=41.9642857142857, Blast_Score=182, Evalue=2e-46,
Organism=Drosophila melanogaster, GI21355415, Length=237, Percent_Identity=37.1308016877637, Blast_Score=146, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005627 [H]

Pfam domain/function: PF03932 CutC [H]

EC number: NA

Molecular weight: Translated: 26380; Mature: 26249

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIQIEVCIDNLESLHNAIAGGADRIELCSSLALGGLTPSFGFMKKAAEISPIPVYAMIR
CCEEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCEEEEEE
PRQGDFLYDNDDISAMISDIQAAKLAGLQGVVFGVLKANGDIDMPLSARLMKIANDNDLG
CCCCCEEECCCHHHHHHHHHHHHHHHCHHHHHHEEEECCCCCCCCHHHHHHHHCCCCCCC
VTFHRAIDQCSNYKKAIENIAELGCERILTSGLAANAYDGINVLADMVKLANGRFDILAG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCEEEEEC
AGVTAENAKEIIEKTGVKEIHLSGKSTRPSKMKLVLDGVKMGAGDLDDFIVPVTDSKKID
CCCCHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEECCCCCCCCCCCEEEECCCCHHHH
AVKQRIK
HHHHHCC
>Mature Secondary Structure 
SIQIEVCIDNLESLHNAIAGGADRIELCSSLALGGLTPSFGFMKKAAEISPIPVYAMIR
CEEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCEEEEEE
PRQGDFLYDNDDISAMISDIQAAKLAGLQGVVFGVLKANGDIDMPLSARLMKIANDNDLG
CCCCCEEECCCHHHHHHHHHHHHHHHCHHHHHHEEEECCCCCCCCHHHHHHHHCCCCCCC
VTFHRAIDQCSNYKKAIENIAELGCERILTSGLAANAYDGINVLADMVKLANGRFDILAG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCEEEEEC
AGVTAENAKEIIEKTGVKEIHLSGKSTRPSKMKLVLDGVKMGAGDLDDFIVPVTDSKKID
CCCCHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEECCCCCCCCCCCEEEECCCCHHHH
AVKQRIK
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA