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The map label for this gene is trxB [H]

Identifier: 59711509

GI number: 59711509

Start: 993855

End: 994820

Strand: Reverse

Name: trxB [H]

Synonym: VF_0902

Alternate gene names: 59711509

Gene position: 994820-993855 (Counterclockwise)

Preceding gene: 59711510

Following gene: 59711508

Centisome position: 34.33

GC content: 42.24

Gene sequence:

>966_bases
ATGAGCAACGTTAAGCATTCAAAATTACTAATTCTTGGTTCTGGTCCTGCGGGTTACACTGCTGCTGTTTACGCTGCACG
AGCTAACTTAAATCCAGTGATGATCACAGGTATGCAACAAGGTGGTCAATTAACAACGACTACTGAAGTTGAAAACTGGC
CTGGCGGTGCTGCCGATATGACTGGCCCAGGCTTAATGGAAGAAATGAAGGCACACGCAGAGCGCTTCAATACTGAAATC
ATTTTTGACCATATCAATGAAACCGATTTTAGCCAACGTCCTTTCCGTCTAAAAGGTGACTCAGGTGAATACACTTGTGA
TGCATTAATTATCTCAACAGGCGCTTCAGCTAAATATTTAGGTTTAGAATCTGAAGAAGCATTTAAAGGTCGTGGCGTTT
CTGCTTGTGCAACATGCGATGGTTTCTTCTACCGTAACCAAAAAGTAGCGGTTGTTGGTGGCGGTAATACTGCTGTTGAA
GAAGCATTATATTTATCAAACATTGCGGCTGAAGTGCACTTAATCCACCGTCGTGACTCTTTCCGCTCTGAAAAGATCTT
AATCGATCGTCTGATGGATAAAGTAGAAAACGGAAACATCATCCTACATACCGACCGTACATTAGAAGAAGTACTAGGTG
ATGATATGGGCGTAACCGGTGTTCGCTTAAAAGACACCAAATCGGATGCTACTGAAGATTTAGAAGTTATGGGCGCGTTT
ATTGCTATTGGCCACCAACCAAATACCGCTATTTTCAATGGTCAGCTTGATATGGAAAATGGCTATATCAAAGTAAAATC
AGGCCTTGAAGGTAATGCGACTCAAACAAGTGTTGAGGGTATTTTTGCTGCAGGTGACGTTATGGATCATAATTACCGCC
AAGCAATTACGTCTGCAGGTACTGGCTGTATGGCCGCTTTAGATGCAGAACGCTTTTTAGATGCGTTAGAAGCAAAAGAA
AGTTAA

Upstream 100 bases:

>100_bases
CCTTTCTTTCATCGAATAAATTCCCTACAATCAGGATATTGGTTGATAACTCGATGTTACCTTCCTCTTTCTCTATTTTT
TGTTTTAGCTCGGAGATCCT

Downstream 100 bases:

>100_bases
ACTATCTATGTTAACGTTAAACCCGAAGTTAATGCTTCGGGTTTCTTTTGCTCATCTTATTTTGTTGATGTGCCTATTTT
TTCTGATATTCAAATTATTA

Product: thioredoxin reductase, FAD/NAD(P)-binding

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MSNVKHSKLLILGSGPAGYTAAVYAARANLNPVMITGMQQGGQLTTTTEVENWPGGAADMTGPGLMEEMKAHAERFNTEI
IFDHINETDFSQRPFRLKGDSGEYTCDALIISTGASAKYLGLESEEAFKGRGVSACATCDGFFYRNQKVAVVGGGNTAVE
EALYLSNIAAEVHLIHRRDSFRSEKILIDRLMDKVENGNIILHTDRTLEEVLGDDMGVTGVRLKDTKSDATEDLEVMGAF
IAIGHQPNTAIFNGQLDMENGYIKVKSGLEGNATQTSVEGIFAAGDVMDHNYRQAITSAGTGCMAALDAERFLDALEAKE
S

Sequences:

>Translated_321_residues
MSNVKHSKLLILGSGPAGYTAAVYAARANLNPVMITGMQQGGQLTTTTEVENWPGGAADMTGPGLMEEMKAHAERFNTEI
IFDHINETDFSQRPFRLKGDSGEYTCDALIISTGASAKYLGLESEEAFKGRGVSACATCDGFFYRNQKVAVVGGGNTAVE
EALYLSNIAAEVHLIHRRDSFRSEKILIDRLMDKVENGNIILHTDRTLEEVLGDDMGVTGVRLKDTKSDATEDLEVMGAF
IAIGHQPNTAIFNGQLDMENGYIKVKSGLEGNATQTSVEGIFAAGDVMDHNYRQAITSAGTGCMAALDAERFLDALEAKE
S
>Mature_320_residues
SNVKHSKLLILGSGPAGYTAAVYAARANLNPVMITGMQQGGQLTTTTEVENWPGGAADMTGPGLMEEMKAHAERFNTEII
FDHINETDFSQRPFRLKGDSGEYTCDALIISTGASAKYLGLESEEAFKGRGVSACATCDGFFYRNQKVAVVGGGNTAVEE
ALYLSNIAAEVHLIHRRDSFRSEKILIDRLMDKVENGNIILHTDRTLEEVLGDDMGVTGVRLKDTKSDATEDLEVMGAFI
AIGHQPNTAIFNGQLDMENGYIKVKSGLEGNATQTSVEGIFAAGDVMDHNYRQAITSAGTGCMAALDAERFLDALEAKES

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=317, Percent_Identity=81.3880126182965, Blast_Score=542, Evalue=1e-155,
Organism=Escherichia coli, GI87081763, Length=314, Percent_Identity=30.8917197452229, Blast_Score=127, Evalue=9e-31,
Organism=Saccharomyces cerevisiae, GI6321898, Length=329, Percent_Identity=46.5045592705167, Blast_Score=284, Evalue=1e-77,
Organism=Saccharomyces cerevisiae, GI6320560, Length=324, Percent_Identity=46.2962962962963, Blast_Score=275, Evalue=9e-75,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34558; Mature: 34427

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNVKHSKLLILGSGPAGYTAAVYAARANLNPVMITGMQQGGQLTTTTEVENWPGGAADM
CCCCCCEEEEEEECCCCCCEEEEEEEECCCCEEEEEEECCCCEEEEEEECCCCCCCCCCC
TGPGLMEEMKAHAERFNTEIIFDHINETDFSQRPFRLKGDSGEYTCDALIISTGASAKYL
CCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCEEEECCCCCEEEEEEEEECCCCEEEE
GLESEEAFKGRGVSACATCDGFFYRNQKVAVVGGGNTAVEEALYLSNIAAEVHLIHRRDS
CCCCCHHHCCCCCEEEEECCCEEEECCEEEEEECCCHHHHHHHHHHHHHHEEEEEECCCC
FRSEKILIDRLMDKVENGNIILHTDRTLEEVLGDDMGVTGVRLKDTKSDATEDLEVMGAF
CCHHHHHHHHHHHHHCCCCEEEECCHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHEEE
IAIGHQPNTAIFNGQLDMENGYIKVKSGLEGNATQTSVEGIFAAGDVMDHNYRQAITSAG
EEECCCCCCEEEECEEECCCCEEEEECCCCCCCCHHHHCEEEEECCHHCCHHHHHHHHCC
TGCMAALDAERFLDALEAKES
CCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SNVKHSKLLILGSGPAGYTAAVYAARANLNPVMITGMQQGGQLTTTTEVENWPGGAADM
CCCCCEEEEEEECCCCCCEEEEEEEECCCCEEEEEEECCCCEEEEEEECCCCCCCCCCC
TGPGLMEEMKAHAERFNTEIIFDHINETDFSQRPFRLKGDSGEYTCDALIISTGASAKYL
CCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCEEEECCCCCEEEEEEEEECCCCEEEE
GLESEEAFKGRGVSACATCDGFFYRNQKVAVVGGGNTAVEEALYLSNIAAEVHLIHRRDS
CCCCCHHHCCCCCEEEEECCCEEEECCEEEEEECCCHHHHHHHHHHHHHHEEEEEECCCC
FRSEKILIDRLMDKVENGNIILHTDRTLEEVLGDDMGVTGVRLKDTKSDATEDLEVMGAF
CCHHHHHHHHHHHHHCCCCEEEECCHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHEEE
IAIGHQPNTAIFNGQLDMENGYIKVKSGLEGNATQTSVEGIFAAGDVMDHNYRQAITSAG
EEECCCCCCEEEECEEECCCCEEEEECCCCCCCCHHHHCEEEEECCHHCCHHHHHHHHCC
TGCMAALDAERFLDALEAKES
CCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]