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The map label for this gene is fldA [H]

Identifier: 59711419

GI number: 59711419

Start: 892088

End: 892615

Strand: Reverse

Name: fldA [H]

Synonym: VF_0812

Alternate gene names: 59711419

Gene position: 892615-892088 (Counterclockwise)

Preceding gene: 59711420

Following gene: 59711417

Centisome position: 30.81

GC content: 39.58

Gene sequence:

>528_bases
ATGGCAAGTGTAGGACTCTTCTTTGGCAGCGATACAGGTAACACTGAAGCTGTTGGCAAGATGATTCAAAAGCAGCTTGG
TAAAAAGCTAGTTCATGTACAAGATATTGCTAAAAGCAGCAAAGAAGATATCGATAATTTCGATCTACTTCTATTAGGTA
TCCCTACATGGTACTACGGTGAAGCTCAATGTGATTGGGATGATTTCTTCCCTGAACTAGAAGAAATTGACTTTTCAACA
AAGCTAGTTGCTATTTTTGGTTGTGGTGACCAAGAAGATTACGCTGAATACTTCTGTGATGCGATGGGTAATATCCGTGA
TATCGTAGAAGCAAAAGGCGGTACTATCATCGGTTACTGGCCAACTGAAGGTTATGAGTTTGAAGCGTCTAAAGCATTAG
TAGATGATGATAACTTTGTTGGTCTATGTATTGATGAAGATCGCCAACCAGAGCTAACTGAAGAGCGTGTTACTAAGTGG
GTAAACCAAATCCACGAAGAAATGTGCTTAGCAGAATTAGAAGACTAA

Upstream 100 bases:

>100_bases
GACTCATCCAGCTGAGCTGGGAAGGTTCTGGACTCAATTAAATTGACTGATCTAACACCATTTATTTTTATTTAATATAG
ACAATACAGGTATTCATCAT

Downstream 100 bases:

>100_bases
TATTCTAATTCCTATAATGCTCTCTGCCTATCACTCATTTAGTGTAGGGAGCATTATCTAAACTCTGGTTTCTTCCTTAC
ATATAATGTTCTATTTACCC

Product: flavodoxin FldA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 175; Mature: 174

Protein sequence:

>175_residues
MASVGLFFGSDTGNTEAVGKMIQKQLGKKLVHVQDIAKSSKEDIDNFDLLLLGIPTWYYGEAQCDWDDFFPELEEIDFST
KLVAIFGCGDQEDYAEYFCDAMGNIRDIVEAKGGTIIGYWPTEGYEFEASKALVDDDNFVGLCIDEDRQPELTEERVTKW
VNQIHEEMCLAELED

Sequences:

>Translated_175_residues
MASVGLFFGSDTGNTEAVGKMIQKQLGKKLVHVQDIAKSSKEDIDNFDLLLLGIPTWYYGEAQCDWDDFFPELEEIDFST
KLVAIFGCGDQEDYAEYFCDAMGNIRDIVEAKGGTIIGYWPTEGYEFEASKALVDDDNFVGLCIDEDRQPELTEERVTKW
VNQIHEEMCLAELED
>Mature_174_residues
ASVGLFFGSDTGNTEAVGKMIQKQLGKKLVHVQDIAKSSKEDIDNFDLLLLGIPTWYYGEAQCDWDDFFPELEEIDFSTK
LVAIFGCGDQEDYAEYFCDAMGNIRDIVEAKGGTIIGYWPTEGYEFEASKALVDDDNFVGLCIDEDRQPELTEERVTKWV
NQIHEEMCLAELED

Specific function: Low-potential electron donor to a number of redox enzymes (Potential). Involved in the reactivation of inactive cob(II)alamin in methionine synthase [H]

COG id: COG0716

COG function: function code C; Flavodoxins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 flavodoxin-like domain [H]

Homologues:

Organism=Escherichia coli, GI1786900, Length=173, Percent_Identity=75.7225433526011, Blast_Score=281, Evalue=2e-77,
Organism=Escherichia coli, GI1789262, Length=168, Percent_Identity=41.6666666666667, Blast_Score=148, Evalue=2e-37,

Paralogues:

None

Copy number: 242 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008254
- InterPro:   IPR001226
- InterPro:   IPR010086 [H]

Pfam domain/function: PF00258 Flavodoxin_1 [H]

EC number: NA

Molecular weight: Translated: 19806; Mature: 19675

Theoretical pI: Translated: 3.81; Mature: 3.81

Prosite motif: PS50902 FLAVODOXIN_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASVGLFFGSDTGNTEAVGKMIQKQLGKKLVHVQDIAKSSKEDIDNFDLLLLGIPTWYYG
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCEECC
EAQCDWDDFFPELEEIDFSTKLVAIFGCGDQEDYAEYFCDAMGNIRDIVEAKGGTIIGYW
CCCCCHHHHCCHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
PTEGYEFEASKALVDDDNFVGLCIDEDRQPELTEERVTKWVNQIHEEMCLAELED
CCCCEEECCCCEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ASVGLFFGSDTGNTEAVGKMIQKQLGKKLVHVQDIAKSSKEDIDNFDLLLLGIPTWYYG
CCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCEECC
EAQCDWDDFFPELEEIDFSTKLVAIFGCGDQEDYAEYFCDAMGNIRDIVEAKGGTIIGYW
CCCCCHHHHCCHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
PTEGYEFEASKALVDDDNFVGLCIDEDRQPELTEERVTKWVNQIHEEMCLAELED
CCCCEEECCCCEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: FMN. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]