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The map label for this gene is fur [H]

Identifier: 59711417

GI number: 59711417

Start: 890946

End: 891389

Strand: Reverse

Name: fur [H]

Synonym: VF_0810

Alternate gene names: 59711417

Gene position: 891389-890946 (Counterclockwise)

Preceding gene: 59711419

Following gene: 59711414

Centisome position: 30.76

GC content: 37.84

Gene sequence:

>444_bases
ATGTCAGATAATAACCAAGCTCTAAAAAAAGCCGGTTTAAAAGTAACCCTTCCGCGCCTTAAAATTTTAGAAGTGCTACA
AGAACCAGAGTGCCAACACATTAGCGCTGAAGATTTGTATAAAAAGCTGATTGATATCGGTGAAGAAATCGGACTTGCAA
CTGTTTACCGTGTATTAAACCAATTTGATGATGCTGGTATCGTCACTCGCCACCATTTTGAAGGCGGTAAATCAGTTTTT
GAATTAGCAACTCAACATCACCATGATCATTTAGTTTGCTTAGATTGTGGAAAAGTAATTGAGTTCTCGGATGAAACAAT
TGAGCAACGTCAAAAACAAGTTGCAGAAAAGTACAATGTCCGTCTAACTAATCACAGTTTGTACCTATATGGTCACTGTA
TAACGGGTGATTGTGCTGATAATGATGATGCACACAACGCTTAA

Upstream 100 bases:

>100_bases
ATCTTGCATATAAGGTTTCAACTGAATTGAATGTTCCCTATAATTAAGTGATTAAAACTGCACAGGAAATCGATGCAGAA
AGCCAAAACAGGAAAAGTCG

Downstream 100 bases:

>100_bases
TTAATCGCTTTTTGCGACAAGCTCATATAAAAAAACCAGCATTTTCATGCTGGTTTTTTATTAGCTAGCAATGATTAATT
AACCAGCCCAAGTATCACGT

Product: ferric uptake regulator

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 147; Mature: 146

Protein sequence:

>147_residues
MSDNNQALKKAGLKVTLPRLKILEVLQEPECQHISAEDLYKKLIDIGEEIGLATVYRVLNQFDDAGIVTRHHFEGGKSVF
ELATQHHHDHLVCLDCGKVIEFSDETIEQRQKQVAEKYNVRLTNHSLYLYGHCITGDCADNDDAHNA

Sequences:

>Translated_147_residues
MSDNNQALKKAGLKVTLPRLKILEVLQEPECQHISAEDLYKKLIDIGEEIGLATVYRVLNQFDDAGIVTRHHFEGGKSVF
ELATQHHHDHLVCLDCGKVIEFSDETIEQRQKQVAEKYNVRLTNHSLYLYGHCITGDCADNDDAHNA
>Mature_146_residues
SDNNQALKKAGLKVTLPRLKILEVLQEPECQHISAEDLYKKLIDIGEEIGLATVYRVLNQFDDAGIVTRHHFEGGKSVFE
LATQHHHDHLVCLDCGKVIEFSDETIEQRQKQVAEKYNVRLTNHSLYLYGHCITGDCADNDDAHNA

Specific function: Fur acts as a repressor, employing Fe(2+) as a cofactor to bind the operator of the iron transport operon [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=147, Percent_Identity=78.9115646258503, Blast_Score=249, Evalue=4e-68,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 16640; Mature: 16509

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDNNQALKKAGLKVTLPRLKILEVLQEPECQHISAEDLYKKLIDIGEEIGLATVYRVLN
CCCCHHHHHHCCCEEECHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHCCHHHHHHHHH
QFDDAGIVTRHHFEGGKSVFELATQHHHDHLVCLDCGKVIEFSDETIEQRQKQVAEKYNV
HCCCCCCEEEEECCCCHHHHHHHHHCCCCCEEEEECCCEEECCHHHHHHHHHHHHHHHCE
RLTNHSLYLYGHCITGDCADNDDAHNA
EEECCEEEEEEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
SDNNQALKKAGLKVTLPRLKILEVLQEPECQHISAEDLYKKLIDIGEEIGLATVYRVLN
CCCHHHHHHCCCEEECHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHCCHHHHHHHHH
QFDDAGIVTRHHFEGGKSVFELATQHHHDHLVCLDCGKVIEFSDETIEQRQKQVAEKYNV
HCCCCCCEEEEECCCCHHHHHHHHHCCCCCEEEEECCCEEECCHHHHHHHHHHHHHHHCE
RLTNHSLYLYGHCITGDCADNDDAHNA
EEECCEEEEEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1372314 [H]