Click here to switch to the map view.

The map label for this gene is nagC [H]

Identifier: 59711413

GI number: 59711413

Start: 884785

End: 885999

Strand: Reverse

Name: nagC [H]

Synonym: VF_0806

Alternate gene names: 59711413

Gene position: 885999-884785 (Counterclockwise)

Preceding gene: 59711414

Following gene: 59711412

Centisome position: 30.58

GC content: 39.09

Gene sequence:

>1215_bases
ATGACTGGCGGACAAATTGGTAATGTAGATCTAGTAAAACAATTAAACAGTGCGGCTGTTTATCGTTTAATCGACCAAAA
AGGTCCGATTTCTCGAATTCAAATTGCAGATGTAAGCCAGCTGGCTCCTGCAAGTGTTACCAAAATCACCCGTCAACTAT
TAGAGCGCGGCTTAATAAAAGAAGTCGCGCAACAAGCATCTACTGGTGGTCGAAGAGCTATCTCCTTGACCACTGAAACC
TCCCCTTTCCACTCTATAGCAGTACGTCTAGGACGAGATTACATTCAACTGAGTTTGTTTGATCTTTCGACTAAAGAGCT
GGCTAGCGAATACCAAGAATTCCATTATAGCAATCAAGAACATCTACTAGATGGGCTGAAATTACTATTGGAAGGCTTTA
TTTCAAAAAACCAAGATACAATTAAGCAATTAATTGCTATCGGCATTACTCTTCCTGGTTTAGTTAACCCTGAAACGGGT
GTGGTTGAATACATGCCAAATACCGATGTAAACAAGCTACTTCTAGCGGATTTCATCAAAGATAATTTTAATACTGAATG
TTTTGTAGGTAACGATGTTCGTGGCCTTGCACTTGCTGAACATTACTTTGGTGCTTCACAAGATTGTTATGATTCGATCT
TAGTCAGTGTTCACCGTGGTACTGGTGCAGGTATTATTGTTAATGGCAAAGTATTTTTAGGTCATAACCGCAATGTAGGT
GAAATTGGTCATATCCAAATTGACCCTATTGGTGATAAATGCCAATGCGGTAATTTTGGTTGCCTAGAAACCGTTGCTGC
TGACCCAGCAATCATTGCACGTGTTGAGTCCTTATTAAAACAAGGCTATCCATCAAGTCTTTCTCAACTACCAAAAATCA
CCATGACAGATATTTGTCATGCTGCAAATCATGGCGATGAGCTAGCGACTCAAACAATATTGCGTGTAGGTAATCAATTA
GGTAAGGCTATTGCGATGACAATAAACTTATTTAATCCTCAAAAGATCGTTATCGCAGGTGCAATTACCCATGCAGATAA
GATCTTATTTGCTGCAATTCGTAACTGTATTAAGAATCAATCATTAACTACTTTCCATAAAGATCTACCAATTGTTGCTT
CTGAGTTATACGACCAACCAACGATCGGGGCATTCTCTATGGTAAAACGTGCGATGCTTAATGGGGTCTTGTTACAAAAA
TTACTCGATGAATAA

Upstream 100 bases:

>100_bases
GGCCGCATTAAAAAGAACATGGTTGCTAACCTTGCTATTTTTGATCGTGACTTCAATGTAAAAGCGACTGTTGTGAACGG
ACAATACGAGCAAAGTTAAT

Downstream 100 bases:

>100_bases
TCACGAGTCTCTATTCACGTGTTATTATTCTAAGGGTTGCTATTAGCAGCCCTTTTTTTCGATTACCATCAGGAACATGA
GTATATGGAGTTACTTTTTA

Product: DNA-binding transcriptional dual regulator, repressor of N-acetylglucosamine

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MTGGQIGNVDLVKQLNSAAVYRLIDQKGPISRIQIADVSQLAPASVTKITRQLLERGLIKEVAQQASTGGRRAISLTTET
SPFHSIAVRLGRDYIQLSLFDLSTKELASEYQEFHYSNQEHLLDGLKLLLEGFISKNQDTIKQLIAIGITLPGLVNPETG
VVEYMPNTDVNKLLLADFIKDNFNTECFVGNDVRGLALAEHYFGASQDCYDSILVSVHRGTGAGIIVNGKVFLGHNRNVG
EIGHIQIDPIGDKCQCGNFGCLETVAADPAIIARVESLLKQGYPSSLSQLPKITMTDICHAANHGDELATQTILRVGNQL
GKAIAMTINLFNPQKIVIAGAITHADKILFAAIRNCIKNQSLTTFHKDLPIVASELYDQPTIGAFSMVKRAMLNGVLLQK
LLDE

Sequences:

>Translated_404_residues
MTGGQIGNVDLVKQLNSAAVYRLIDQKGPISRIQIADVSQLAPASVTKITRQLLERGLIKEVAQQASTGGRRAISLTTET
SPFHSIAVRLGRDYIQLSLFDLSTKELASEYQEFHYSNQEHLLDGLKLLLEGFISKNQDTIKQLIAIGITLPGLVNPETG
VVEYMPNTDVNKLLLADFIKDNFNTECFVGNDVRGLALAEHYFGASQDCYDSILVSVHRGTGAGIIVNGKVFLGHNRNVG
EIGHIQIDPIGDKCQCGNFGCLETVAADPAIIARVESLLKQGYPSSLSQLPKITMTDICHAANHGDELATQTILRVGNQL
GKAIAMTINLFNPQKIVIAGAITHADKILFAAIRNCIKNQSLTTFHKDLPIVASELYDQPTIGAFSMVKRAMLNGVLLQK
LLDE
>Mature_403_residues
TGGQIGNVDLVKQLNSAAVYRLIDQKGPISRIQIADVSQLAPASVTKITRQLLERGLIKEVAQQASTGGRRAISLTTETS
PFHSIAVRLGRDYIQLSLFDLSTKELASEYQEFHYSNQEHLLDGLKLLLEGFISKNQDTIKQLIAIGITLPGLVNPETGV
VEYMPNTDVNKLLLADFIKDNFNTECFVGNDVRGLALAEHYFGASQDCYDSILVSVHRGTGAGIIVNGKVFLGHNRNVGE
IGHIQIDPIGDKCQCGNFGCLETVAADPAIIARVESLLKQGYPSSLSQLPKITMTDICHAANHGDELATQTILRVGNQLG
KAIAMTINLFNPQKIVIAGAITHADKILFAAIRNCIKNQSLTTFHKDLPIVASELYDQPTIGAFSMVKRAMLNGVLLQKL
LDE

Specific function: Acts as a repressor of the nagEBACD operon and acts both as an activator and a repressor for the transcription of the glmSU operon [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566315, Length=291, Percent_Identity=24.7422680412371, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI298566325, Length=291, Percent_Identity=24.7422680412371, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI4885285, Length=291, Percent_Identity=24.7422680412371, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI190014632, Length=291, Percent_Identity=24.7422680412371, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1786891, Length=406, Percent_Identity=62.5615763546798, Blast_Score=501, Evalue=1e-143,
Organism=Escherichia coli, GI1787878, Length=400, Percent_Identity=38.5, Blast_Score=292, Evalue=3e-80,
Organism=Escherichia coli, GI87082127, Length=197, Percent_Identity=28.9340101522843, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87081733, Length=226, Percent_Identity=26.1061946902655, Blast_Score=78, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR; PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 43944; Mature: 43813

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGGQIGNVDLVKQLNSAAVYRLIDQKGPISRIQIADVSQLAPASVTKITRQLLERGLIK
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHCCCHHHHHHHHHHHHHHHHH
EVAQQASTGGRRAISLTTETSPFHSIAVRLGRDYIQLSLFDLSTKELASEYQEFHYSNQE
HHHHHHCCCCCEEEEEEECCCHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHCCCHH
HLLDGLKLLLEGFISKNQDTIKQLIAIGITLPGLVNPETGVVEYMPNTDVNKLLLADFIK
HHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHH
DNFNTECFVGNDVRGLALAEHYFGASQDCYDSILVSVHRGTGAGIIVNGKVFLGHNRNVG
CCCCCEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHEECCCCCEEEEECEEEECCCCCCC
EIGHIQIDPIGDKCQCGNFGCLETVAADPAIIARVESLLKQGYPSSLSQLPKITMTDICH
CCCCEEECCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHH
AANHGDELATQTILRVGNQLGKAIAMTINLFNPQKIVIAGAITHADKILFAAIRNCIKNQ
HCCCCHHHHHHHHHHHHHHHHHEEEEEEEECCCCEEEEEEEHHHHHHHHHHHHHHHHCCC
SLTTFHKDLPIVASELYDQPTIGAFSMVKRAMLNGVLLQKLLDE
CCHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TGGQIGNVDLVKQLNSAAVYRLIDQKGPISRIQIADVSQLAPASVTKITRQLLERGLIK
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHCCCHHHHHHHHHHHHHHHHH
EVAQQASTGGRRAISLTTETSPFHSIAVRLGRDYIQLSLFDLSTKELASEYQEFHYSNQE
HHHHHHCCCCCEEEEEEECCCHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHCCCHH
HLLDGLKLLLEGFISKNQDTIKQLIAIGITLPGLVNPETGVVEYMPNTDVNKLLLADFIK
HHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHH
DNFNTECFVGNDVRGLALAEHYFGASQDCYDSILVSVHRGTGAGIIVNGKVFLGHNRNVG
CCCCCEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHEECCCCCEEEEECEEEECCCCCCC
EIGHIQIDPIGDKCQCGNFGCLETVAADPAIIARVESLLKQGYPSSLSQLPKITMTDICH
CCCCEEECCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHH
AANHGDELATQTILRVGNQLGKAIAMTINLFNPQKIVIAGAITHADKILFAAIRNCIKNQ
HCCCCHHHHHHHHHHHHHHHHHEEEEEEEECCCCEEEEEEEHHHHHHHHHHHHHHHHCCC
SLTTFHKDLPIVASELYDQPTIGAFSMVKRAMLNGVLLQKLLDE
CCHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]