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The map label for this gene is nagA [H]

Identifier: 59711414

GI number: 59711414

Start: 886001

End: 887137

Strand: Reverse

Name: nagA [H]

Synonym: VF_0807

Alternate gene names: 59711414

Gene position: 887137-886001 (Counterclockwise)

Preceding gene: 59711417

Following gene: 59711413

Centisome position: 30.62

GC content: 41.16

Gene sequence:

>1137_bases
ATGTATGCGCTAACTAACTGTAAAGTTTATACAGGTAACGATGTTCTTACTGATCATTCAGTAATCATTAATGGAACAGA
GATTGAAGCTGTTTGCCCAACATCAGAACTACCAGCTGGTATTGAGCTAAAAGACTTAGATGGAGCGATTCTAAGCCCAG
GCTTTATCGATCTTCAGCTTAATGGTTGTGGCGGCGTAATGCTTAATGATGAAATTACAGCAGAAACCATGCAAATTATG
CATGAAGCAAACCTAAAATCTGGCTGTACTAGCTTCTTACCAACATTGATTACTTCTTCTGATGAAGATATGCGTGCGGC
AATCGAAGCAGCTCGTGAATACCACAGCAAATATCAAAACCAATCTTTAGGTTTGCACCTAGAAGGTCCATACCTAAACG
TAATGAAAAAAGGCATTCACAGCGTTGATCATATCCGTACGTCAGATTCAGACATGATCCAACTTATGTGCGATAACGCA
GACCTAATCGCAAAAGTAACGCTAGCGCCAGAGCAAAATGATCCTGAGCATATCGAGCGCCTTCATAAAGCAGGTATCGT
GGTATCTATTGGCCACACAAACGCAACTTATGCTGAAGCTCGTCAAGGATTTGAGTCAGGTATCACTTTCGCAACTCACT
TGTTTAATGCAATGACGCCTATGGTTGGTCGTGAACCTGGTGTTGTGGGTGCAATTTATGATACTCCAGACGTTTATGCT
GGCATCATTGCTGATGGTTTCCATGTTGACTATGCAAACATCCGTATTGCACACAAAATAAAGAAAGAAAAACTAGTATT
AGTGACCGATGCCACAGCTCCTGCAGGTGCTGACATGGAATACTTTATTTTTGTGGGTAAGAAAGTATATTACAAGGATG
GCAAATGTGTTGATGAAAATGGCACATTAGGTGGCTCAGCTCTGACTATGATTGAAGCAGTTCAGAATACAGTTGAGCAC
GTTGGAATCGCTTTAGACGAAGCACTACGCATGGCGACTTTATATCCAGCTCAAGCTATGGGCTTAGATAATAAACTTGG
CCGCATTAAAAAGAACATGGTTGCTAACCTTGCTATTTTTGATCGTGACTTCAATGTAAAAGCGACTGTTGTGAACGGAC
AATACGAGCAAAGTTAA

Upstream 100 bases:

>100_bases
TACCGCTCAGTAAGCAGTTCTATTTTCACCTGCTTAAAAATTTCAACGAAAAAAGTTTATTTTTTTTCGTACTCTAAATT
ATAACCAAAGGATTCAAGCT

Downstream 100 bases:

>100_bases
TATGACTGGCGGACAAATTGGTAATGTAGATCTAGTAAAACAATTAAACAGTGCGGCTGTTTATCGTTTAATCGACCAAA
AAGGTCCGATTTCTCGAATT

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MYALTNCKVYTGNDVLTDHSVIINGTEIEAVCPTSELPAGIELKDLDGAILSPGFIDLQLNGCGGVMLNDEITAETMQIM
HEANLKSGCTSFLPTLITSSDEDMRAAIEAAREYHSKYQNQSLGLHLEGPYLNVMKKGIHSVDHIRTSDSDMIQLMCDNA
DLIAKVTLAPEQNDPEHIERLHKAGIVVSIGHTNATYAEARQGFESGITFATHLFNAMTPMVGREPGVVGAIYDTPDVYA
GIIADGFHVDYANIRIAHKIKKEKLVLVTDATAPAGADMEYFIFVGKKVYYKDGKCVDENGTLGGSALTMIEAVQNTVEH
VGIALDEALRMATLYPAQAMGLDNKLGRIKKNMVANLAIFDRDFNVKATVVNGQYEQS

Sequences:

>Translated_378_residues
MYALTNCKVYTGNDVLTDHSVIINGTEIEAVCPTSELPAGIELKDLDGAILSPGFIDLQLNGCGGVMLNDEITAETMQIM
HEANLKSGCTSFLPTLITSSDEDMRAAIEAAREYHSKYQNQSLGLHLEGPYLNVMKKGIHSVDHIRTSDSDMIQLMCDNA
DLIAKVTLAPEQNDPEHIERLHKAGIVVSIGHTNATYAEARQGFESGITFATHLFNAMTPMVGREPGVVGAIYDTPDVYA
GIIADGFHVDYANIRIAHKIKKEKLVLVTDATAPAGADMEYFIFVGKKVYYKDGKCVDENGTLGGSALTMIEAVQNTVEH
VGIALDEALRMATLYPAQAMGLDNKLGRIKKNMVANLAIFDRDFNVKATVVNGQYEQS
>Mature_378_residues
MYALTNCKVYTGNDVLTDHSVIINGTEIEAVCPTSELPAGIELKDLDGAILSPGFIDLQLNGCGGVMLNDEITAETMQIM
HEANLKSGCTSFLPTLITSSDEDMRAAIEAAREYHSKYQNQSLGLHLEGPYLNVMKKGIHSVDHIRTSDSDMIQLMCDNA
DLIAKVTLAPEQNDPEHIERLHKAGIVVSIGHTNATYAEARQGFESGITFATHLFNAMTPMVGREPGVVGAIYDTPDVYA
GIIADGFHVDYANIRIAHKIKKEKLVLVTDATAPAGADMEYFIFVGKKVYYKDGKCVDENGTLGGSALTMIEAVQNTVEH
VGIALDEALRMATLYPAQAMGLDNKLGRIKKNMVANLAIFDRDFNVKATVVNGQYEQS

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=420, Percent_Identity=31.4285714285714, Blast_Score=175, Evalue=5e-44,
Organism=Homo sapiens, GI224922791, Length=419, Percent_Identity=31.5035799522673, Blast_Score=174, Evalue=9e-44,
Organism=Escherichia coli, GI1786892, Length=377, Percent_Identity=59.6816976127321, Blast_Score=477, Evalue=1e-136,
Organism=Caenorhabditis elegans, GI17553768, Length=388, Percent_Identity=32.2164948453608, Blast_Score=169, Evalue=2e-42,
Organism=Drosophila melanogaster, GI19920392, Length=387, Percent_Identity=33.3333333333333, Blast_Score=172, Evalue=3e-43,
Organism=Drosophila melanogaster, GI281361140, Length=401, Percent_Identity=31.6708229426434, Blast_Score=165, Evalue=4e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 41074; Mature: 41074

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYALTNCKVYTGNDVLTDHSVIINGTEIEAVCPTSELPAGIELKDLDGAILSPGFIDLQL
CEEEEEEEEEECCCEEECCEEEEECCEEEEECCCCCCCCCCEEECCCCCEECCCEEEEEE
NGCGGVMLNDEITAETMQIMHEANLKSGCTSFLPTLITSSDEDMRAAIEAAREYHSKYQN
CCCCCEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC
QSLGLHLEGPYLNVMKKGIHSVDHIRTSDSDMIQLMCDNADLIAKVTLAPEQNDPEHIER
CCCCEEECCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEEECCCCCCHHHHHH
LHKAGIVVSIGHTNATYAEARQGFESGITFATHLFNAMTPMVGREPGVVGAIYDTPDVYA
HHHCCEEEEECCCCCHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHH
GIIADGFHVDYANIRIAHKIKKEKLVLVTDATAPAGADMEYFIFVGKKVYYKDGKCVDEN
HHEECCEEEEEEEEEEEEEECCCEEEEEEECCCCCCCCEEEEEEECCEEEECCCEEECCC
GTLGGSALTMIEAVQNTVEHVGIALDEALRMATLYPAQAMGLDNKLGRIKKNMVANLAIF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHEEEEEE
DRDFNVKATVVNGQYEQS
ECCCCEEEEEECCCCCCC
>Mature Secondary Structure
MYALTNCKVYTGNDVLTDHSVIINGTEIEAVCPTSELPAGIELKDLDGAILSPGFIDLQL
CEEEEEEEEEECCCEEECCEEEEECCEEEEECCCCCCCCCCEEECCCCCEECCCEEEEEE
NGCGGVMLNDEITAETMQIMHEANLKSGCTSFLPTLITSSDEDMRAAIEAAREYHSKYQN
CCCCCEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC
QSLGLHLEGPYLNVMKKGIHSVDHIRTSDSDMIQLMCDNADLIAKVTLAPEQNDPEHIER
CCCCEEECCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEEECCCCCCHHHHHH
LHKAGIVVSIGHTNATYAEARQGFESGITFATHLFNAMTPMVGREPGVVGAIYDTPDVYA
HHHCCEEEEECCCCCHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHH
GIIADGFHVDYANIRIAHKIKKEKLVLVTDATAPAGADMEYFIFVGKKVYYKDGKCVDEN
HHEECCEEEEEEEEEEEEEECCCEEEEEEECCCCCCCCEEEEEEECCEEEECCCEEECCC
GTLGGSALTMIEAVQNTVEHVGIALDEALRMATLYPAQAMGLDNKLGRIKKNMVANLAIF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHEEEEEE
DRDFNVKATVVNGQYEQS
ECCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9301118; 10952301 [H]