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The map label for this gene is nikC [C]

Identifier: 59711286

GI number: 59711286

Start: 740731

End: 741495

Strand: Reverse

Name: nikC [C]

Synonym: VF_0679

Alternate gene names: 59711286

Gene position: 741495-740731 (Counterclockwise)

Preceding gene: 59711287

Following gene: 59711285

Centisome position: 25.59

GC content: 38.3

Gene sequence:

>765_bases
ATGCTTAAAAAGCACCTTCCTTTATTATTGTTTTGCATATTAATTCTGATTTCCATTACTTGGCAAAACAATGGCGAAAC
CATTAATTTATTTAATCGAAACATCGCACCAAATTCACTCGACTGGTTTGGCACAGATTGGCTTGGAAGAGATGTATTTA
GCCGTACATTAAAGGCTCTATTGTTTAGTCTTGCTATGGGAGGAATATCTTCTGTTTTATGTACTGTGCTTTCTCTCTGC
TTAGCTTTAATTGGCAATATCAACAATACACTGAATAACATCATTAACCTTCTTGTTGATGTATGGAGTTCCCTTCCACA
TATCCTACTCATGATCGTACTATCCGTATTAGTTGGCGGTGGGTTTGAAGGGCTTGTCATTGCTATTACATTGAGTCATT
GGCCAAAACTGACACGTCTATTAAAAGTTGAGATAGAACAGCTTAGGAAAAAGCCTTACGTCTTACATTCGTTATCGTTT
GGTCATTCAAAAGTGCATACCTATGTTGTTCACATAACACCTCACGTTTTACCTCAAATGTTAATTGGTATGTTGCTGCT
ATACCCTCAAGCATTAGTTCATGGGGCTGGACTCACTTTTTTAGGTTTTGGTATCGCTCCCTCAACCCCCTCTATGGGTG
GTATGCTATCAGAAGCCAGCCAATACCTACTCAGTGGGCAGTGGTGGTTAGCTTTGTTTCCGGGGATAGTGTTAGTAATA
AGCTCATTGCTATTAATATCAATTGGTAAGTCATATGAAAAATAA

Upstream 100 bases:

>100_bases
ATGCTGCGCTCTATTTGTTTTTATTGGTAATGCTACTGCATCATTGTTAAGTAAACGACTTTCGTTATCGACATCGTTTT
AATTTTAAAGGGGATGTTCC

Downstream 100 bases:

>100_bases
AAACAGCATAGTACTTGAGTTAAAAGCGTTAGAAATCAGATTAACAGCAGATACAACCCCTTTATTTTCTAATCTGTCGC
TGTCTTTAAAGCAAGGTGAA

Product: oligopeptide transport system permease protein OppC

Products: Ni2; [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MLKKHLPLLLFCILILISITWQNNGETINLFNRNIAPNSLDWFGTDWLGRDVFSRTLKALLFSLAMGGISSVLCTVLSLC
LALIGNINNTLNNIINLLVDVWSSLPHILLMIVLSVLVGGGFEGLVIAITLSHWPKLTRLLKVEIEQLRKKPYVLHSLSF
GHSKVHTYVVHITPHVLPQMLIGMLLLYPQALVHGAGLTFLGFGIAPSTPSMGGMLSEASQYLLSGQWWLALFPGIVLVI
SSLLLISIGKSYEK

Sequences:

>Translated_254_residues
MLKKHLPLLLFCILILISITWQNNGETINLFNRNIAPNSLDWFGTDWLGRDVFSRTLKALLFSLAMGGISSVLCTVLSLC
LALIGNINNTLNNIINLLVDVWSSLPHILLMIVLSVLVGGGFEGLVIAITLSHWPKLTRLLKVEIEQLRKKPYVLHSLSF
GHSKVHTYVVHITPHVLPQMLIGMLLLYPQALVHGAGLTFLGFGIAPSTPSMGGMLSEASQYLLSGQWWLALFPGIVLVI
SSLLLISIGKSYEK
>Mature_254_residues
MLKKHLPLLLFCILILISITWQNNGETINLFNRNIAPNSLDWFGTDWLGRDVFSRTLKALLFSLAMGGISSVLCTVLSLC
LALIGNINNTLNNIINLLVDVWSSLPHILLMIVLSVLVGGGFEGLVIAITLSHWPKLTRLLKVEIEQLRKKPYVLHSLSF
GHSKVHTYVVHITPHVLPQMLIGMLLLYPQALVHGAGLTFLGFGIAPSTPSMGGMLSEASQYLLSGQWWLALFPGIVLVI
SSLLLISIGKSYEK

Specific function: Probably part of the binding-protein-dependent transport system y4tOPQRS for a peptide. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789889, Length=235, Percent_Identity=31.063829787234, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1787054, Length=250, Percent_Identity=28, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787760, Length=242, Percent_Identity=27.6859504132231, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1789964, Length=238, Percent_Identity=30.2521008403361, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788505, Length=219, Percent_Identity=26.4840182648402, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787549, Length=240, Percent_Identity=23.3333333333333, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 27972; Mature: 27972

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKKHLPLLLFCILILISITWQNNGETINLFNRNIAPNSLDWFGTDWLGRDVFSRTLKAL
CCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHH
LFSLAMGGISSVLCTVLSLCLALIGNINNTLNNIINLLVDVWSSLPHILLMIVLSVLVGG
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GFEGLVIAITLSHWPKLTRLLKVEIEQLRKKPYVLHSLSFGHSKVHTYVVHITPHVLPQM
CCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHEEEEECHHHHHHH
LIGMLLLYPQALVHGAGLTFLGFGIAPSTPSMGGMLSEASQYLLSGQWWLALFPGIVLVI
HHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHH
SSLLLISIGKSYEK
HHHHHHHHHHCCCC
>Mature Secondary Structure
MLKKHLPLLLFCILILISITWQNNGETINLFNRNIAPNSLDWFGTDWLGRDVFSRTLKAL
CCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHH
LFSLAMGGISSVLCTVLSLCLALIGNINNTLNNIINLLVDVWSSLPHILLMIVLSVLVGG
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GFEGLVIAITLSHWPKLTRLLKVEIEQLRKKPYVLHSLSFGHSKVHTYVVHITPHVLPQM
CCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHEEEEECHHHHHHH
LIGMLLLYPQALVHGAGLTFLGFGIAPSTPSMGGMLSEASQYLLSGQWWLALFPGIVLVI
HHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHH
SSLLLISIGKSYEK
HHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; ATP; H2O [C]

Specific reaction: Ni2+ [Periplasm] + ATP + H2O = Ni2+ [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8796346; 9163424 [H]