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The map label for this gene is cph2 [H]

Identifier: 59711203

GI number: 59711203

Start: 654308

End: 655870

Strand: Reverse

Name: cph2 [H]

Synonym: VF_0596

Alternate gene names: 59711203

Gene position: 655870-654308 (Counterclockwise)

Preceding gene: 59711204

Following gene: 59711202

Centisome position: 22.64

GC content: 36.08

Gene sequence:

>1563_bases
ATGATTGAAGTATCCATTGTTGCCTCTGAATTAAACCAGCTTAAGCAACAGCTAGATCAAACGCGCCTATCACACCGAGA
CACTACGTTAAAATCACGTCGTGAAATAATGCTATTAAAGCGTATTATTTTGCGTTTTTGTGCTGCGTGTAAACATCATG
ATAGTGAACTAGATAAAGAGATTGTTGAACTTGCTACCAGCATTGAACAAGTTGAGAATACATCAGACCTTACGGTTCGT
ATTGCTACTTTTGAACGCTTAATTAATAGATATAAGCAGAATGTTCAAAAAGAGCATTCAATGATGGAAGATCATATTTC
TTATTGTGGTGAAACGTTACAACGAGTCATTGGCTTACCTGCCGGACTTAAAAGAGACCTTCGTAACTTATTACAACACC
CTTCTCACGATGGTAGTAAACACATTCATCGTATTGTTCGACTTATTGAACTCTATGAGCGAGCGATCAAATTCATTTCA
GTAGGTCAGTTATCATCTGAAATCAATTCCAATGAAATTATTGATGTCGATACCCAAGAACAATTAAGTAATGAACTACA
ACATTTAATCTCTGAATTAGATTTTGACAGTACTTCAGGAAAAGACTTACTTGAGATCCGCAATAAACTACTGACAGGTG
TCGATGCTGTATCTTTAATTGATCTTGCACTTCAAACCTTAAAGTTAGTATTGGAAGGCACAAACAATGAACGTAAAGCA
TCACAAGCGTTTGTTGGTGAAATGAATACACAAGTTGCTCAAATCATAAAAACAAGTGAACAAAATCAAGAAAAAAGCCA
GGCTTATTTAGAACAAAGATCCCTATTAAATGAAGAATACTCCCTGCTAGTAAAGCAAGCTGAGAACTTATTAAATAGTA
AAGTAAGCATGCAAGAGCATAAAGCTCAAATGGCTCTACTACTCAGTGAAATGAGTGATTTATCTGAACGTAATAAAGCA
ATGCAAGAGCGTGAAGCAGCATTAATTGAGCGACACGAATATGCAACCAAAAAGCTCAATACGCTTTATGAAGAAACTCT
AGAGTATCGCCGTCAGCTTAATAACCAGCAACAACGAATTTTCAAAGATCCACTAACCAAAGTTTATAATCGGGCAGCAA
TGCACGAACGTCTCGATTTAGAATATAAACGCTGGGTACGCCATCAACACTCTTTAGTGCTTAGTATCATCGACATCGAT
CAGTTCAAACGTATTAATAAAAATTACGGTCATTTGGCTGGAGATAAAGCGCTTAGCATTATCGCAAAAACCATTGAAAA
CCAAGTATCAGATACTAATTTTGTTGCTCGTTTTAGTGGCGAAGAATTTTTAATTTTATTTACTGAAACCACTGAAGATG
AAAGAAAGAAGGTATTAGCCAATATCCAATCGGCGATTGCGAAACTGCCATTCAAATTCAAAGATAACCATGTAAAAATC
ACGGTTTCAATTTGCAGCTCAGAGTTCACAAACAGTGATATACCTGAGAAAGTTATTGAACGTTCAATACAAGCGTTATA
CAAGCAAAAAACAAAAGGCATTGAGCAACTCATTAGTGCGTAG

Upstream 100 bases:

>100_bases
CTTTATTTTAGTCAGTTACTAATATCTTTGTTACTATGAAAATATTGACCTATTTATAGGTTACCGCTATCTATCAATGT
GAGTTTTTACCTAAGTTATT

Downstream 100 bases:

>100_bases
TTATCATTAGAATTTCGTTTTTTTACTGATAACTAAATACCAAATAGCATTATAACCCTCTCAGTTTTTTACAATTTTCC
TAGCAAAAGTCTCTTTTGCT

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: Bacteriophytochrome cph2 [H]

Number of amino acids: Translated: 520; Mature: 520

Protein sequence:

>520_residues
MIEVSIVASELNQLKQQLDQTRLSHRDTTLKSRREIMLLKRIILRFCAACKHHDSELDKEIVELATSIEQVENTSDLTVR
IATFERLINRYKQNVQKEHSMMEDHISYCGETLQRVIGLPAGLKRDLRNLLQHPSHDGSKHIHRIVRLIELYERAIKFIS
VGQLSSEINSNEIIDVDTQEQLSNELQHLISELDFDSTSGKDLLEIRNKLLTGVDAVSLIDLALQTLKLVLEGTNNERKA
SQAFVGEMNTQVAQIIKTSEQNQEKSQAYLEQRSLLNEEYSLLVKQAENLLNSKVSMQEHKAQMALLLSEMSDLSERNKA
MQEREAALIERHEYATKKLNTLYEETLEYRRQLNNQQQRIFKDPLTKVYNRAAMHERLDLEYKRWVRHQHSLVLSIIDID
QFKRINKNYGHLAGDKALSIIAKTIENQVSDTNFVARFSGEEFLILFTETTEDERKKVLANIQSAIAKLPFKFKDNHVKI
TVSICSSEFTNSDIPEKVIERSIQALYKQKTKGIEQLISA

Sequences:

>Translated_520_residues
MIEVSIVASELNQLKQQLDQTRLSHRDTTLKSRREIMLLKRIILRFCAACKHHDSELDKEIVELATSIEQVENTSDLTVR
IATFERLINRYKQNVQKEHSMMEDHISYCGETLQRVIGLPAGLKRDLRNLLQHPSHDGSKHIHRIVRLIELYERAIKFIS
VGQLSSEINSNEIIDVDTQEQLSNELQHLISELDFDSTSGKDLLEIRNKLLTGVDAVSLIDLALQTLKLVLEGTNNERKA
SQAFVGEMNTQVAQIIKTSEQNQEKSQAYLEQRSLLNEEYSLLVKQAENLLNSKVSMQEHKAQMALLLSEMSDLSERNKA
MQEREAALIERHEYATKKLNTLYEETLEYRRQLNNQQQRIFKDPLTKVYNRAAMHERLDLEYKRWVRHQHSLVLSIIDID
QFKRINKNYGHLAGDKALSIIAKTIENQVSDTNFVARFSGEEFLILFTETTEDERKKVLANIQSAIAKLPFKFKDNHVKI
TVSICSSEFTNSDIPEKVIERSIQALYKQKTKGIEQLISA
>Mature_520_residues
MIEVSIVASELNQLKQQLDQTRLSHRDTTLKSRREIMLLKRIILRFCAACKHHDSELDKEIVELATSIEQVENTSDLTVR
IATFERLINRYKQNVQKEHSMMEDHISYCGETLQRVIGLPAGLKRDLRNLLQHPSHDGSKHIHRIVRLIELYERAIKFIS
VGQLSSEINSNEIIDVDTQEQLSNELQHLISELDFDSTSGKDLLEIRNKLLTGVDAVSLIDLALQTLKLVLEGTNNERKA
SQAFVGEMNTQVAQIIKTSEQNQEKSQAYLEQRSLLNEEYSLLVKQAENLLNSKVSMQEHKAQMALLLSEMSDLSERNKA
MQEREAALIERHEYATKKLNTLYEETLEYRRQLNNQQQRIFKDPLTKVYNRAAMHERLDLEYKRWVRHQHSLVLSIIDID
QFKRINKNYGHLAGDKALSIIAKTIENQVSDTNFVARFSGEEFLILFTETTEDERKKVLANIQSAIAKLPFKFKDNHVKI
TVSICSSEFTNSDIPEKVIERSIQALYKQKTKGIEQLISA

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral membrane protein (Potential) [C]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 GGDEF domains [H]

Homologues:

Organism=Escherichia coli, GI1787802, Length=156, Percent_Identity=33.3333333333333, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI145693134, Length=152, Percent_Identity=30.9210526315789, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1787816, Length=192, Percent_Identity=26.0416666666667, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI87081881, Length=127, Percent_Identity=31.496062992126, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI87082007, Length=107, Percent_Identity=33.6448598130841, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1788956, Length=210, Percent_Identity=27.6190476190476, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786584, Length=107, Percent_Identity=32.7102803738318, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1787262, Length=157, Percent_Identity=27.3885350318471, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1787056, Length=168, Percent_Identity=27.3809523809524, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1788085, Length=96, Percent_Identity=36.4583333333333, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR003018
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515 [H]

Pfam domain/function: PF00563 EAL; PF01590 GAF; PF00990 GGDEF; PF00360 Phytochrome [H]

EC number: NA

Molecular weight: Translated: 60049; Mature: 60049

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEVSIVASELNQLKQQLDQTRLSHRDTTLKSRREIMLLKRIILRFCAACKHHDSELDKE
CEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
IVELATSIEQVENTSDLTVRIATFERLINRYKQNVQKEHSMMEDHISYCGETLQRVIGLP
HHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AGLKRDLRNLLQHPSHDGSKHIHRIVRLIELYERAIKFISVGQLSSEINSNEIIDVDTQE
CHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCHH
QLSNELQHLISELDFDSTSGKDLLEIRNKLLTGVDAVSLIDLALQTLKLVLEGTNNERKA
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
SQAFVGEMNTQVAQIIKTSEQNQEKSQAYLEQRSLLNEEYSLLVKQAENLLNSKVSMQEH
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAQMALLLSEMSDLSERNKAMQEREAALIERHEYATKKLNTLYEETLEYRRQLNNQQQRI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
FKDPLTKVYNRAAMHERLDLEYKRWVRHQHSLVLSIIDIDQFKRINKNYGHLAGDKALSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
IAKTIENQVSDTNFVARFSGEEFLILFTETTEDERKKVLANIQSAIAKLPFKFKDNHVKI
HHHHHHHHCCCCCHHEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
TVSICSSEFTNSDIPEKVIERSIQALYKQKTKGIEQLISA
EEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIEVSIVASELNQLKQQLDQTRLSHRDTTLKSRREIMLLKRIILRFCAACKHHDSELDKE
CEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
IVELATSIEQVENTSDLTVRIATFERLINRYKQNVQKEHSMMEDHISYCGETLQRVIGLP
HHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AGLKRDLRNLLQHPSHDGSKHIHRIVRLIELYERAIKFISVGQLSSEINSNEIIDVDTQE
CHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCHH
QLSNELQHLISELDFDSTSGKDLLEIRNKLLTGVDAVSLIDLALQTLKLVLEGTNNERKA
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
SQAFVGEMNTQVAQIIKTSEQNQEKSQAYLEQRSLLNEEYSLLVKQAENLLNSKVSMQEH
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAQMALLLSEMSDLSERNKAMQEREAALIERHEYATKKLNTLYEETLEYRRQLNNQQQRI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
FKDPLTKVYNRAAMHERLDLEYKRWVRHQHSLVLSIIDIDQFKRINKNYGHLAGDKALSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
IAKTIENQVSDTNFVARFSGEEFLILFTETTEDERKKVLANIQSAIAKLPFKFKDNHVKI
HHHHHHHHCCCCCHHEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
TVSICSSEFTNSDIPEKVIERSIQALYKQKTKGIEQLISA
EEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10978170; 11063585 [H]