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The map label for this gene is phoQ2 [H]

Identifier: 59711131

GI number: 59711131

Start: 559068

End: 560030

Strand: Reverse

Name: phoQ2 [H]

Synonym: VF_0524

Alternate gene names: 59711131

Gene position: 560030-559068 (Counterclockwise)

Preceding gene: 59711132

Following gene: 59711115

Centisome position: 19.33

GC content: 32.29

Gene sequence:

>963_bases
ATGACAAATCTAAATAATAATTATGGATTTTATCGGATCTTTTTTTCTTTAATCCTAGGAATTCTGCTCTTTAGTACTCC
AATTTTGTTTCTAATATATAAGCAAACGGAACAACCAATAATATTAATTACGGTGGGAACATTGCTAAGTTTCATCGTCT
TTATTTACTTTAGTTACCAATGGGCAATTAAACCGATAAAGAAGAGAAAACGAGAGTTAAAACGCATCCAAAACATGAAA
GAAGGTTTCTTTACTCAACCAAGTGACACTGAATCAGAATTAACATCAATTTACCACTCAACTAACCGTGCCCTCTTTCA
AGCAAAAGAAAAAGAAGAACAATACAAAAAAACACTCGATGATTTAGCTCATAGTTTAAAAAATCATGTTATCGCATCAA
AACTATTGCTACAGGATCTGCAAGCCGAATCAACAGAAAAGCTCTCTCAACAATTAACTTTAATGGATGATGTTATCCAA
GGTCAGTTACAAAGAGCCACATTAAATATTAAAGAATTAAAACCAACAACAACTGTGGTAAGTGAACCATTACAAGGGTT
ACTCTCCATGTTTAGTAAGATCTACCATGAAAAAGAAATTGAGGTTTGTTGTTTTATCAATGAAGAACAAAAGCTACCAA
TAGAAAAAAATGATTTGATGGAAATACTAGGTAACACTCTAGAGAATAGTTTTCGATTCGCATCGACAAAGATCGTTATT
ACCATTAAACAATATAGTAACGATTATATATTGAGCATTGAAAATGATGGCCCATCAATTCCTGAAGAACAAAAAGAATC
GTTATTTTTACGAGGCGTTAGAGCTGATAAACTGAATGCAGGTACCGGATTAGGACTTGCTTTATGTGCTGATATTATTG
AGAAATATAATGGAAGTATTTGGTTTGACACTCCAGAGAATAAACGTTTAGGTGCACTACTAAAAATAAAGCTACCTATT
TAG

Upstream 100 bases:

>100_bases
TGAAGAGATCATATCCAGTTATAACGGGCAAATCTGGTTCCATACACAAGATACCGGCTCAAGATTAGAAATATTTTTAC
CACATCAAATATAAGTAATA

Downstream 100 bases:

>100_bases
CAAACAAAGGCGGTATTCCAACCTTTCGTTAGTAACACCGCCTATCTTTAACTATCAATTAGTTTCGTTAGCTTTTTTCT
CAATATCAACTCGGCGATTA

Product: sensory histidine kinase in two-compoent regulatory system with PhoP

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MTNLNNNYGFYRIFFSLILGILLFSTPILFLIYKQTEQPIILITVGTLLSFIVFIYFSYQWAIKPIKKRKRELKRIQNMK
EGFFTQPSDTESELTSIYHSTNRALFQAKEKEEQYKKTLDDLAHSLKNHVIASKLLLQDLQAESTEKLSQQLTLMDDVIQ
GQLQRATLNIKELKPTTTVVSEPLQGLLSMFSKIYHEKEIEVCCFINEEQKLPIEKNDLMEILGNTLENSFRFASTKIVI
TIKQYSNDYILSIENDGPSIPEEQKESLFLRGVRADKLNAGTGLGLALCADIIEKYNGSIWFDTPENKRLGALLKIKLPI

Sequences:

>Translated_320_residues
MTNLNNNYGFYRIFFSLILGILLFSTPILFLIYKQTEQPIILITVGTLLSFIVFIYFSYQWAIKPIKKRKRELKRIQNMK
EGFFTQPSDTESELTSIYHSTNRALFQAKEKEEQYKKTLDDLAHSLKNHVIASKLLLQDLQAESTEKLSQQLTLMDDVIQ
GQLQRATLNIKELKPTTTVVSEPLQGLLSMFSKIYHEKEIEVCCFINEEQKLPIEKNDLMEILGNTLENSFRFASTKIVI
TIKQYSNDYILSIENDGPSIPEEQKESLFLRGVRADKLNAGTGLGLALCADIIEKYNGSIWFDTPENKRLGALLKIKLPI
>Mature_319_residues
TNLNNNYGFYRIFFSLILGILLFSTPILFLIYKQTEQPIILITVGTLLSFIVFIYFSYQWAIKPIKKRKRELKRIQNMKE
GFFTQPSDTESELTSIYHSTNRALFQAKEKEEQYKKTLDDLAHSLKNHVIASKLLLQDLQAESTEKLSQQLTLMDDVIQG
QLQRATLNIKELKPTTTVVSEPLQGLLSMFSKIYHEKEIEVCCFINEEQKLPIEKNDLMEILGNTLENSFRFASTKIVIT
IKQYSNDYILSIENDGPSIPEEQKESLFLRGVRADKLNAGTGLGLALCADIIEKYNGSIWFDTPENKRLGALLKIKLPI

Specific function: Member of the two-component regulatory system phoQ/phoP which regulates the expression of genes involved in virulence and resistance to host defense antimicrobial peptides. In presence of low periplasmic Mg(2+) concentrations, phoQ functions as a membrane

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787374, Length=271, Percent_Identity=30.2583025830258, Blast_Score=130, Evalue=8e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR015014
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF08918 PhoQ_Sensor [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 36772; Mature: 36641

Theoretical pI: Translated: 7.49; Mature: 7.49

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNLNNNYGFYRIFFSLILGILLFSTPILFLIYKQTEQPIILITVGTLLSFIVFIYFSYQ
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCEEEEEHHHHHHHHHHHHHHHH
WAIKPIKKRKRELKRIQNMKEGFFTQPSDTESELTSIYHSTNRALFQAKEKEEQYKKTLD
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLAHSLKNHVIASKLLLQDLQAESTEKLSQQLTLMDDVIQGQLQRATLNIKELKPTTTVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHH
SEPLQGLLSMFSKIYHEKEIEVCCFINEEQKLPIEKNDLMEILGNTLENSFRFASTKIVI
HHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHEEEEEEEEE
TIKQYSNDYILSIENDGPSIPEEQKESLFLRGVRADKLNAGTGLGLALCADIIEKYNGSI
EEEECCCCEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCE
WFDTPENKRLGALLKIKLPI
EEECCCCCCCCEEEEEEECC
>Mature Secondary Structure 
TNLNNNYGFYRIFFSLILGILLFSTPILFLIYKQTEQPIILITVGTLLSFIVFIYFSYQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCEEEEEHHHHHHHHHHHHHHHH
WAIKPIKKRKRELKRIQNMKEGFFTQPSDTESELTSIYHSTNRALFQAKEKEEQYKKTLD
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLAHSLKNHVIASKLLLQDLQAESTEKLSQQLTLMDDVIQGQLQRATLNIKELKPTTTVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHH
SEPLQGLLSMFSKIYHEKEIEVCCFINEEQKLPIEKNDLMEILGNTLENSFRFASTKIVI
HHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHEEEEEEEEE
TIKQYSNDYILSIENDGPSIPEEQKESLFLRGVRADKLNAGTGLGLALCADIIEKYNGSI
EEEECCCCEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCE
WFDTPENKRLGALLKIKLPI
EEECCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA