Click here to switch to the map view.

The map label for this gene is napA [H]

Identifier: 55981441

GI number: 55981441

Start: 1403088

End: 1404248

Strand: Reverse

Name: napA [H]

Synonym: TTHA1472

Alternate gene names: 55981441

Gene position: 1404248-1403088 (Counterclockwise)

Preceding gene: 55981442

Following gene: 55981439

Centisome position: 75.92

GC content: 66.93

Gene sequence:

>1161_bases
ATGCACGGCGCGGAACACCTGTTGGAGATCTTCTATCTCCTTCTCGCGGCCCAGGTGATGGCCTTTATCTTCAAGCGCCT
GAACCAGCCCGTGGTCATCGGGGAGGTGCTGGCGGGGGTGCTGGTGGGGCCGGCCCTCCTCGGCCTGGTGCACGAGGGGG
AGATCCTGGAGTTTCTGGCGGAGCTCGGGGCCGTCTTCCTCCTCTTCATGGTGGGCTTGGAGACCAGGCTTAAGGACATC
CTGGCGGTGGGGAAGGAGGCCTTTTTGGTGGCCGTTTTGGGGGTGGCCCTGCCCTTCCTAGGGGGGTACCTCTACGGCCT
AGAGATCGGGTTTGAAACCCTCCCCGCCCTCTTCCTCGGCACCGCCTTGGTGGCCACTAGCGTAGGTATAACCGCGAGGG
TCCTCCAGGAGCTCGGGGTTCTTTCCCGCCCCTATTCCCGGATCATCCTGGGGGCGGCGGTGATTGACGATGTCCTGGGC
CTCATCGTCCTTGCGGTGGTGAACGGCGTGGCGGAGACGGGCCAGGTGGAGGTGGGGGCCATCACCCGGCTTATCGTCCT
CTCCGTGGTCTTCGTGGGGCTTGCCGTCTTCCTCTCCACCCTCATCGCCCGCCTCCCCCTGGAGCGGCTTCCCGTGGGGA
GCCCCTTGGGCTTCGCCCTCGCCTTGGGCGTGGGGATGGCGGCCCTGGCGGCCAGCATCGGCCTCGCCCCCATCGTGGGG
GCCTTCCTCGGGGGAATGCTTCTCTCCGAGGTGCGGGAAAAGTACCGTCTGGAGGAGCCCATCTTCGCCATAGAGAGCTT
CCTCGCCCCCATTTTCTTCGCCATGGTGGGGGTGAGGCTGGAGCTTTCCGCCTTGGCGAGCCCCGTGGTGCTGGTGGCGG
GGACGGTGGTTACGGTCATCGCCATCCTGGGCAAGGTCCTGGGCGGCTTCCTCGGCGCCCTCACCCAAGGGGTGCGGAGC
GCCCTCACCGTGGGGGTGGGCATGGCCCCCCGGGGGGAGGTGGGCCTCATCGTGGCCGCCTTGGGCCTCAAGGCGGGGGC
GGTGAACGAGGAGGAGTACGCCATCGTCCTCTTCATGGTGGTCTTCACGACCCTCTTCGCCCCCTTCGCCCTGAAGCCCC
TCATCGCCTGGACGGAGAGGGAGCGCGCCGCTAAGGAATAG

Upstream 100 bases:

>100_bases
CGACCGACCTACGCCACCTCCCGGTGGTGGACGAGGAGGGCAAGGTGGTGGGCATCCTCACCCGGAGCGACTTTTTGAAG
CTCATCCTAGGGAGGGGTTG

Downstream 100 bases:

>100_bases
CCTTGTAGGCGGCGTAGGCGGAGAGCACCTTGGCGAGGTACTCCCGGGGCTCGTCCCGCTCTTGGAAGCGGAGGAAGGCG
TAGAGACCCCCCTCCCGGGC

Product: Na(+)/H(+) antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MHGAEHLLEIFYLLLAAQVMAFIFKRLNQPVVIGEVLAGVLVGPALLGLVHEGEILEFLAELGAVFLLFMVGLETRLKDI
LAVGKEAFLVAVLGVALPFLGGYLYGLEIGFETLPALFLGTALVATSVGITARVLQELGVLSRPYSRIILGAAVIDDVLG
LIVLAVVNGVAETGQVEVGAITRLIVLSVVFVGLAVFLSTLIARLPLERLPVGSPLGFALALGVGMAALAASIGLAPIVG
AFLGGMLLSEVREKYRLEEPIFAIESFLAPIFFAMVGVRLELSALASPVVLVAGTVVTVIAILGKVLGGFLGALTQGVRS
ALTVGVGMAPRGEVGLIVAALGLKAGAVNEEEYAIVLFMVVFTTLFAPFALKPLIAWTERERAAKE

Sequences:

>Translated_386_residues
MHGAEHLLEIFYLLLAAQVMAFIFKRLNQPVVIGEVLAGVLVGPALLGLVHEGEILEFLAELGAVFLLFMVGLETRLKDI
LAVGKEAFLVAVLGVALPFLGGYLYGLEIGFETLPALFLGTALVATSVGITARVLQELGVLSRPYSRIILGAAVIDDVLG
LIVLAVVNGVAETGQVEVGAITRLIVLSVVFVGLAVFLSTLIARLPLERLPVGSPLGFALALGVGMAALAASIGLAPIVG
AFLGGMLLSEVREKYRLEEPIFAIESFLAPIFFAMVGVRLELSALASPVVLVAGTVVTVIAILGKVLGGFLGALTQGVRS
ALTVGVGMAPRGEVGLIVAALGLKAGAVNEEEYAIVLFMVVFTTLFAPFALKPLIAWTERERAAKE
>Mature_386_residues
MHGAEHLLEIFYLLLAAQVMAFIFKRLNQPVVIGEVLAGVLVGPALLGLVHEGEILEFLAELGAVFLLFMVGLETRLKDI
LAVGKEAFLVAVLGVALPFLGGYLYGLEIGFETLPALFLGTALVATSVGITARVLQELGVLSRPYSRIILGAAVIDDVLG
LIVLAVVNGVAETGQVEVGAITRLIVLSVVFVGLAVFLSTLIARLPLERLPVGSPLGFALALGVGMAALAASIGLAPIVG
AFLGGMLLSEVREKYRLEEPIFAIESFLAPIFFAMVGVRLELSALASPVVLVAGTVVTVIAILGKVLGGFLGALTQGVRS
ALTVGVGMAPRGEVGLIVAALGLKAGAVNEEEYAIVLFMVVFTTLFAPFALKPLIAWTERERAAKE

Specific function: This is a Na(+)/H(+) antiporter. It can mediate sodium uptake when a transmembrane pH gradient is applied [H]

COG id: COG0475

COG function: function code P; Kef-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family [H]

Homologues:

Organism=Escherichia coli, GI1786685, Length=396, Percent_Identity=27.5252525252525, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1789749, Length=389, Percent_Identity=25.4498714652956, Blast_Score=62, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322367, Length=390, Percent_Identity=26.4102564102564, Blast_Score=91, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR004771 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 40287; Mature: 40287

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHGAEHLLEIFYLLLAAQVMAFIFKRLNQPVVIGEVLAGVLVGPALLGLVHEGEILEFLA
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
ELGAVFLLFMVGLETRLKDILAVGKEAFLVAVLGVALPFLGGYLYGLEIGFETLPALFLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TALVATSVGITARVLQELGVLSRPYSRIILGAAVIDDVLGLIVLAVVNGVAETGQVEVGA
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
ITRLIVLSVVFVGLAVFLSTLIARLPLERLPVGSPLGFALALGVGMAALAASIGLAPIVG
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AFLGGMLLSEVREKYRLEEPIFAIESFLAPIFFAMVGVRLELSALASPVVLVAGTVVTVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AILGKVLGGFLGALTQGVRSALTVGVGMAPRGEVGLIVAALGLKAGAVNEEEYAIVLFMV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHH
VFTTLFAPFALKPLIAWTERERAAKE
HHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MHGAEHLLEIFYLLLAAQVMAFIFKRLNQPVVIGEVLAGVLVGPALLGLVHEGEILEFLA
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
ELGAVFLLFMVGLETRLKDILAVGKEAFLVAVLGVALPFLGGYLYGLEIGFETLPALFLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TALVATSVGITARVLQELGVLSRPYSRIILGAAVIDDVLGLIVLAVVNGVAETGQVEVGA
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
ITRLIVLSVVFVGLAVFLSTLIARLPLERLPVGSPLGFALALGVGMAALAASIGLAPIVG
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AFLGGMLLSEVREKYRLEEPIFAIESFLAPIFFAMVGVRLELSALASPVVLVAGTVVTVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AILGKVLGGFLGALTQGVRSALTVGVGMAPRGEVGLIVAALGLKAGAVNEEEYAIVLFMV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHH
VFTTLFAPFALKPLIAWTERERAAKE
HHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1312090; 1325937 [H]