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The map label for this gene is dnaC [H]

Identifier: 55981439

GI number: 55981439

Start: 1400048

End: 1401382

Strand: Reverse

Name: dnaC [H]

Synonym: TTHA1470

Alternate gene names: 55981439

Gene position: 1401382-1400048 (Counterclockwise)

Preceding gene: 55981441

Following gene: 55981436

Centisome position: 75.76

GC content: 68.69

Gene sequence:

>1335_bases
ATGGAAGGCCGTATCCCCCCCCACAGCCTCGAGGCGGAGCAGAGCGTCCTGGGGGCGATCCTCCTGGACTATCAAGTCCT
GGACGAGATTGAGGGCCTGCTCCCCACCCCCGAGGCCTTCTACGCCGAGGCCCACCGCAAGATCTACGCCGCCATGCAGG
GCCTGAGGGCCGAGGGCAGCCCCGTGGACCTGGTGACCCTCGCCGAGGAGCTTTCCCGCCGGGGGGAGCTGGACGGGGTG
GGGGGGATCAGCTACCTGATGCAGCTTTCCGAGGCCACCCCCACCGCCGCTTACGCCGAGCACTACGCCCGCATCGTGGC
GGAGAAGTGGACCCTGCGCAGGCTCATCCAGGCGGCCGGGGAGGCCATGCGCCTCGCCTACGAGGAGGCGGGAAGCCTGG
ACGAGATCCTGGACCAGGCGGGGAAGCGGATCCTGGAGGTGGCCCTGGCCCAGACGGAGGTGGAGGCCCGCTCCATGCGG
GAGCTCGTCCACGAGACCTTTGAGCACATTGAGGCCCTCTTCCAGAACAAGGGGGAGACCGCCGGGGTGCGCACGGGCTT
CAAGGAGCTGGACCAGCTCATCGGCACCCTCGCCCCCGGCTCCCTGAACATCATCGCCGCCCGCCCCGCCATGGGGAAGA
CCGCCTTCGCCCTCACCATCGCCCAGCACGCCGCCCTCAAGGAGGGGGTGGGGGTGGGGATCTACTCCCTGGAGATGCCC
GCGGCCCAGCTCGTCCTCCGGATGATGTGCTCCGAGGCCCGCATTGACATGAACCGGGTCCGGCTCGGCCAGCTTTCCGA
CCGGGACTTCTCCCGCCTCGTGGACGTGGCGGGCCGGCTTTCCGAGGCCCCCATCTTCATTGACGACACCCCCGACCTGA
CCCTCATGGAACTCCGCGCCCGGGCCCGGAGGCTCAGGAGCCAGCACAACGTGGGCCTGATCATCATAGACTACCTCCAG
CTCATGTCGGGGCCCGGAGGGGGGCAGAAGGGGGAGAACCGGCAGCAGGAGATCGCCGCCATCTCCAGGGGGCTCAAGGC
CTTGGCCCGGGAGCTCGGCGTGCCGGTGATCGCCTTAAGCCAGCTCTCCCGGGCGGTGGAGGCGCGGCCCAACAAGCGCC
CCATGCTCTCCGACCTCAGGGAGTCGGGCTCCATTGAACAGGACGCCGACCTGGTGATGTTCATCTACCGGGACGAGTAC
TACAACCCCCACTCGGAGAAGGCGGGGATCGCCGAGATCATCGTGGGCAAGCAGCGCAACGGCCCCACGGGGACCGTGGA
GCTCCAGTTCCACGCCCAGCACGTGCGCTTCAACGACCTGGCCAAGGAGCCCTAG

Upstream 100 bases:

>100_bases
GCTTAGGCCCCTCCCCTGAGAAGCGGAAAAGAGCCAATCCTTCCCACAAGGAAAGGCCTCTGGCGGAAGGAGGGGAGGCG
GGCTTAACCTGGGGAGGCTT

Downstream 100 bases:

>100_bases
GCCCGGGAGAGGAGGGCCGAGGCCCCCTCCTTGAGGGCTTGGGTGAGGTCCCGGTGCCCCAGGGAAAGGCCTAAGGAGAG
GGCCTCGAGGTAGCTCTCCT

Product: replicative DNA helicase DnaB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MEGRIPPHSLEAEQSVLGAILLDYQVLDEIEGLLPTPEAFYAEAHRKIYAAMQGLRAEGSPVDLVTLAEELSRRGELDGV
GGISYLMQLSEATPTAAYAEHYARIVAEKWTLRRLIQAAGEAMRLAYEEAGSLDEILDQAGKRILEVALAQTEVEARSMR
ELVHETFEHIEALFQNKGETAGVRTGFKELDQLIGTLAPGSLNIIAARPAMGKTAFALTIAQHAALKEGVGVGIYSLEMP
AAQLVLRMMCSEARIDMNRVRLGQLSDRDFSRLVDVAGRLSEAPIFIDDTPDLTLMELRARARRLRSQHNVGLIIIDYLQ
LMSGPGGGQKGENRQQEIAAISRGLKALARELGVPVIALSQLSRAVEARPNKRPMLSDLRESGSIEQDADLVMFIYRDEY
YNPHSEKAGIAEIIVGKQRNGPTGTVELQFHAQHVRFNDLAKEP

Sequences:

>Translated_444_residues
MEGRIPPHSLEAEQSVLGAILLDYQVLDEIEGLLPTPEAFYAEAHRKIYAAMQGLRAEGSPVDLVTLAEELSRRGELDGV
GGISYLMQLSEATPTAAYAEHYARIVAEKWTLRRLIQAAGEAMRLAYEEAGSLDEILDQAGKRILEVALAQTEVEARSMR
ELVHETFEHIEALFQNKGETAGVRTGFKELDQLIGTLAPGSLNIIAARPAMGKTAFALTIAQHAALKEGVGVGIYSLEMP
AAQLVLRMMCSEARIDMNRVRLGQLSDRDFSRLVDVAGRLSEAPIFIDDTPDLTLMELRARARRLRSQHNVGLIIIDYLQ
LMSGPGGGQKGENRQQEIAAISRGLKALARELGVPVIALSQLSRAVEARPNKRPMLSDLRESGSIEQDADLVMFIYRDEY
YNPHSEKAGIAEIIVGKQRNGPTGTVELQFHAQHVRFNDLAKEP
>Mature_444_residues
MEGRIPPHSLEAEQSVLGAILLDYQVLDEIEGLLPTPEAFYAEAHRKIYAAMQGLRAEGSPVDLVTLAEELSRRGELDGV
GGISYLMQLSEATPTAAYAEHYARIVAEKWTLRRLIQAAGEAMRLAYEEAGSLDEILDQAGKRILEVALAQTEVEARSMR
ELVHETFEHIEALFQNKGETAGVRTGFKELDQLIGTLAPGSLNIIAARPAMGKTAFALTIAQHAALKEGVGVGIYSLEMP
AAQLVLRMMCSEARIDMNRVRLGQLSDRDFSRLVDVAGRLSEAPIFIDDTPDLTLMELRARARRLRSQHNVGLIIIDYLQ
LMSGPGGGQKGENRQQEIAAISRGLKALARELGVPVIALSQLSRAVEARPNKRPMLSDLRESGSIEQDADLVMFIYRDEY
YNPHSEKAGIAEIIVGKQRNGPTGTVELQFHAQHVRFNDLAKEP

Specific function: Participates In Initiation And Elongation During Chromosome Replication; It Exhibits DNA-Dependent ATPase Activity And Contains Distinct Active Sites For ATP Binding, DNA Binding, And Interaction With DNAc Protein, Primase, And Other Prepriming Proteins.

COG id: COG0305

COG function: function code L; Replicative DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SF4 helicase domain [H]

Homologues:

Organism=Escherichia coli, GI1790486, Length=444, Percent_Identity=47.5225225225225, Blast_Score=397, Evalue=1e-111,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007692
- InterPro:   IPR007694
- InterPro:   IPR007693
- InterPro:   IPR016136 [H]

Pfam domain/function: PF00772 DnaB; PF03796 DnaB_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 48854; Mature: 48854

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGRIPPHSLEAEQSVLGAILLDYQVLDEIEGLLPTPEAFYAEAHRKIYAAMQGLRAEGS
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
PVDLVTLAEELSRRGELDGVGGISYLMQLSEATPTAAYAEHYARIVAEKWTLRRLIQAAG
CCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EAMRLAYEEAGSLDEILDQAGKRILEVALAQTEVEARSMRELVHETFEHIEALFQNKGET
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AGVRTGFKELDQLIGTLAPGSLNIIAARPAMGKTAFALTIAQHAALKEGVGVGIYSLEMP
CHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCC
AAQLVLRMMCSEARIDMNRVRLGQLSDRDFSRLVDVAGRLSEAPIFIDDTPDLTLMELRA
HHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHH
RARRLRSQHNVGLIIIDYLQLMSGPGGGQKGENRQQEIAAISRGLKALARELGVPVIALS
HHHHHHHHCCCCEEHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHH
QLSRAVEARPNKRPMLSDLRESGSIEQDADLVMFIYRDEYYNPHSEKAGIAEIIVGKQRN
HHHHHHHCCCCCCCHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHCCCCCC
GPTGTVELQFHAQHVRFNDLAKEP
CCCCEEEEEEEECHHHHHHHCCCC
>Mature Secondary Structure
MEGRIPPHSLEAEQSVLGAILLDYQVLDEIEGLLPTPEAFYAEAHRKIYAAMQGLRAEGS
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
PVDLVTLAEELSRRGELDGVGGISYLMQLSEATPTAAYAEHYARIVAEKWTLRRLIQAAG
CCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EAMRLAYEEAGSLDEILDQAGKRILEVALAQTEVEARSMRELVHETFEHIEALFQNKGET
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AGVRTGFKELDQLIGTLAPGSLNIIAARPAMGKTAFALTIAQHAALKEGVGVGIYSLEMP
CHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCC
AAQLVLRMMCSEARIDMNRVRLGQLSDRDFSRLVDVAGRLSEAPIFIDDTPDLTLMELRA
HHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHH
RARRLRSQHNVGLIIIDYLQLMSGPGGGQKGENRQQEIAAISRGLKALARELGVPVIALS
HHHHHHHHCCCCEEHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHH
QLSRAVEARPNKRPMLSDLRESGSIEQDADLVMFIYRDEYYNPHSEKAGIAEIIVGKQRN
HHHHHHHCCCCCCCHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHCCCCCC
GPTGTVELQFHAQHVRFNDLAKEP
CCCCEEEEEEEECHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 1312531 [H]