Click here to switch to the map view.

The map label for this gene is pcp [H]

Identifier: 55980857

GI number: 55980857

Start: 845052

End: 845630

Strand: Reverse

Name: pcp [H]

Synonym: TTHA0888

Alternate gene names: 55980857

Gene position: 845630-845052 (Counterclockwise)

Preceding gene: 55980862

Following gene: 55980856

Centisome position: 45.72

GC content: 71.5

Gene sequence:

>579_bases
ATGATCCTCGTCACCGGCTTTGAACCCTTCGGCAGCCTGGAACACAACCCCTCCCAGGCCCTCCTTGACCTCCTCCCCTC
CGAGGTGGACGGCAAGCCCCTCAGGAAGGCCGTCCTCCCCGTGGACGCCGAGGCCCTGGGAGAGGCCCTGGAGGACCTCC
ACCGGGAGGGGCCCAAGGCCGTCCTCCACCTGGGGCTTGCGGAGGACCGGCCCGTCCTCACCCTGGAGAGGCTCGCGGTG
AACCTTTTGGACTTCCCCCGCCCCGACAACCGGGGCCGGGTCCTCGAGGACCTCCCCATCGTCCCTGGAGGCCCCCTGGC
CCTTCCCGCCCGCTTCCCGGTGAAGCCCGTCCTCGCCCGCTGGCGCGAGGCGGGCATCCCCGGAAGGCCGAGCCTCTCCG
CGGGGAGCTACCTCTGCAACCAGGCCTTCTACCTCTCCCTCTACCGCCTGCCCGAGGAAGTCCCCGTGGGCTTCCTCCAC
CTTCCTCCCGACGAGACCCTGGCCCTCAAGCGGCCCAGGCCCTACGTGCCCCTGGAGGTCCAGGCCCGGGCCGTCCGCCT
CGCCCTGGAGCACCTGTGA

Upstream 100 bases:

>100_bases
CGGGTGACCCTGCCCCGCTCCAGGTGTCGGTCACGAGTCCGAGCTCCACGCCCCCTATGGTATACCGCGTCCAAGCCCTG
GCTATAATGCTCCCTGGCCC

Downstream 100 bases:

>100_bases
GGGTCCTCTTCCTCTCCGACGCCCGGCGCATCGGGGGAAGCGAGGTCTATCTCAGGGAGATGCTTCCCCGGGTGAAGGCC
CTGGGGCTCTCCCCCGAGGC

Product: pyrrolidone carboxyl peptidase

Products: NA

Alternate protein names: 5-oxoprolyl-peptidase; Pyroglutamyl-peptidase I; PGP-I; Pyrase [H]

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MILVTGFEPFGSLEHNPSQALLDLLPSEVDGKPLRKAVLPVDAEALGEALEDLHREGPKAVLHLGLAEDRPVLTLERLAV
NLLDFPRPDNRGRVLEDLPIVPGGPLALPARFPVKPVLARWREAGIPGRPSLSAGSYLCNQAFYLSLYRLPEEVPVGFLH
LPPDETLALKRPRPYVPLEVQARAVRLALEHL

Sequences:

>Translated_192_residues
MILVTGFEPFGSLEHNPSQALLDLLPSEVDGKPLRKAVLPVDAEALGEALEDLHREGPKAVLHLGLAEDRPVLTLERLAV
NLLDFPRPDNRGRVLEDLPIVPGGPLALPARFPVKPVLARWREAGIPGRPSLSAGSYLCNQAFYLSLYRLPEEVPVGFLH
LPPDETLALKRPRPYVPLEVQARAVRLALEHL
>Mature_192_residues
MILVTGFEPFGSLEHNPSQALLDLLPSEVDGKPLRKAVLPVDAEALGEALEDLHREGPKAVLHLGLAEDRPVLTLERLAV
NLLDFPRPDNRGRVLEDLPIVPGGPLALPARFPVKPVLARWREAGIPGRPSLSAGSYLCNQAFYLSLYRLPEEVPVGFLH
LPPDETLALKRPRPYVPLEVQARAVRLALEHL

Specific function: Removes 5-oxoproline from various penultimate amino acid residues except L-proline [H]

COG id: COG2039

COG function: function code O; Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C15 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000816
- InterPro:   IPR016125 [H]

Pfam domain/function: PF01470 Peptidase_C15 [H]

EC number: =3.4.19.3 [H]

Molecular weight: Translated: 21120; Mature: 21120

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILVTGFEPFGSLEHNPSQALLDLLPSEVDGKPLRKAVLPVDAEALGEALEDLHREGPKA
CEEEECCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHCCCCE
VLHLGLAEDRPVLTLERLAVNLLDFPRPDNRGRVLEDLPIVPGGPLALPARFPVKPVLAR
EEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCCCCEECCCCCCHHHHHHH
WREAGIPGRPSLSAGSYLCNQAFYLSLYRLPEEVPVGFLHLPPDETLALKRPRPYVPLEV
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHCCCCEEECCCCCCEEECCCCCCCCHHH
QARAVRLALEHL
HHHHHHHHHHCC
>Mature Secondary Structure
MILVTGFEPFGSLEHNPSQALLDLLPSEVDGKPLRKAVLPVDAEALGEALEDLHREGPKA
CEEEECCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHCCCCE
VLHLGLAEDRPVLTLERLAVNLLDFPRPDNRGRVLEDLPIVPGGPLALPARFPVKPVLAR
EEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCCCCEECCCCCCHHHHHHH
WREAGIPGRPSLSAGSYLCNQAFYLSLYRLPEEVPVGFLHLPPDETLALKRPRPYVPLEV
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHCCCCEEECCCCCCEEECCCCCCCCHHH
QARAVRLALEHL
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]