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The map label for this gene is cysS [H]

Identifier: 55980862

GI number: 55980862

Start: 854263

End: 855705

Strand: Reverse

Name: cysS [H]

Synonym: TTHA0893

Alternate gene names: 55980862

Gene position: 855705-854263 (Counterclockwise)

Preceding gene: 55980867

Following gene: 55980857

Centisome position: 46.26

GC content: 67.29

Gene sequence:

>1443_bases
ATGGGCCTGGTCATCTACGACACCCTGGCGCGCCGCAAAGTGCCCTTTGAGCCCGCGGTCCCCGGCCACGTGGGGATCTA
CGTCTGCGGCCCCACGGTCTACGCCGACCCCCACCTGGGCCACGCCCGGGGTCCCGTGGTCTACGACGTCCTGAGGCGCT
ACCTCCTCCACAAGGGCTACAAGGTGCGCTTCGTCTCCAACATCACCGACGTGGGCCACCTCACCGACGACGCCGACGAG
GGCGAGGACAAGATCGTGAGGCGGGCCAAGCTGGAACGGCTTGAGCCCATGGAGGTGGCCGAGAAGTACACCTGGAGCTA
CTTTGACGCCATGCAGGCCCTGAACGTCCTCAGGCCCTCCATCGCCCCGAGGGCTTCAGGCCACATCCCGGAGATGCTGG
AGCTCACGGAAAGGCTTCTTGCGCGGGGGGTGGCCTACGAGCGGAAGGGAAGCGTCTACTTCCGGGTGCGCTCCTTCCCC
GAGTACGGGAAGCTCTCAGGAAAGCGCCTGGAGGAGCTCAGGGCGGGGGCCCGGGTGGAGGTGCGGGAGGAGAAGGAAGA
CCCCCTGGACTTCGCCCTCTGGAAGGCGGCCGAGCCCGGGCACATCATGCGCTGGAAGAGCCCCTGGGGGGAGGGGTACC
CCGGCTGGCACATTGAGTGCACGGCCATGAGCCTCAAGTACCTGGGGGAAGGCTTTGACCTCCACGCCGGGGGGATTGAC
CTGCAGTTTCCCCACCACGAGTGCGAGATCGCCCAGGCGGAGGCCGCGGGCTTCCGCTTCGCCCGGCACTGGATGCACCA
CAACCACGTCCTCCTGGAGGGGGAGAAGATGGCCAAGAGCACGGGGAACCTCGTCCTCCTCCACGACCTCCTCGAGGCCC
ACGAGCCCATGGCCCTCCGCTTCTACCTCCTCCAGACCCACTACCGGAGCCCCATGGACTTCACCTGGGAAGGGCTGGAA
AGCGCCAAAAGGGGGTATGGCCGCCTCCTCCACGCCTACCGGGAGGTGCGGGGGCGCAAGAAGACCGCACCCCCCGGCAC
CACCCCCGAGCTGGAAAGGGCCCTGGACGCCCTGGAAAAGGCCTTCATGGAGGCCATAGAGGACGACCTCTCCACTCCCG
AGGCCCTGGCCGCCCTCTTCGCCTTCCTCCCCGAGCTCCACAAGCTCCTCCCCGAGGCCAAGGCGGAAAGCCTCGCCCGG
GCCGAGGCGGTCTTCCACACCTTGGGGGAAGGGATCCTCGGCCTCTTTCCCGAGAGGGTCCTGGAGGAAAGGGTCTCCGG
GCCCCTCCTCGAGGGCCTCATCGCCCTCCTCCTGGAGCTTAGGGAAGAGGCGAGGCGGGCCAAGGACTACGAAAAAAGCG
ACCTCATCCGGGAAAGGTTAAGGGCCCTCGGCGTCATCGTGGAGGACACCAAGGAGGGCCCGAGGTGGCGCCTGGAGCGC
TAA

Upstream 100 bases:

>100_bases
TGGTCTCGGCGGCCACCACCCTCAGATCCCCCTCCCCGGCCAGGCCCCTAAGGATCCGTCCCATACCCCGCCATTATGCC
ACGGGCCCTATAATCGCCCT

Downstream 100 bases:

>100_bases
AGAGCCCCCGTGCGGGGCAAGCCCGCACGGGGGGTAAGATCACCCCACGCTGGCGTCAGCGCGGGATGGGGTAGCCCCCG
GCCTCCAGCACCGCCTCCGC

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 480; Mature: 479

Protein sequence:

>480_residues
MGLVIYDTLARRKVPFEPAVPGHVGIYVCGPTVYADPHLGHARGPVVYDVLRRYLLHKGYKVRFVSNITDVGHLTDDADE
GEDKIVRRAKLERLEPMEVAEKYTWSYFDAMQALNVLRPSIAPRASGHIPEMLELTERLLARGVAYERKGSVYFRVRSFP
EYGKLSGKRLEELRAGARVEVREEKEDPLDFALWKAAEPGHIMRWKSPWGEGYPGWHIECTAMSLKYLGEGFDLHAGGID
LQFPHHECEIAQAEAAGFRFARHWMHHNHVLLEGEKMAKSTGNLVLLHDLLEAHEPMALRFYLLQTHYRSPMDFTWEGLE
SAKRGYGRLLHAYREVRGRKKTAPPGTTPELERALDALEKAFMEAIEDDLSTPEALAALFAFLPELHKLLPEAKAESLAR
AEAVFHTLGEGILGLFPERVLEERVSGPLLEGLIALLLELREEARRAKDYEKSDLIRERLRALGVIVEDTKEGPRWRLER

Sequences:

>Translated_480_residues
MGLVIYDTLARRKVPFEPAVPGHVGIYVCGPTVYADPHLGHARGPVVYDVLRRYLLHKGYKVRFVSNITDVGHLTDDADE
GEDKIVRRAKLERLEPMEVAEKYTWSYFDAMQALNVLRPSIAPRASGHIPEMLELTERLLARGVAYERKGSVYFRVRSFP
EYGKLSGKRLEELRAGARVEVREEKEDPLDFALWKAAEPGHIMRWKSPWGEGYPGWHIECTAMSLKYLGEGFDLHAGGID
LQFPHHECEIAQAEAAGFRFARHWMHHNHVLLEGEKMAKSTGNLVLLHDLLEAHEPMALRFYLLQTHYRSPMDFTWEGLE
SAKRGYGRLLHAYREVRGRKKTAPPGTTPELERALDALEKAFMEAIEDDLSTPEALAALFAFLPELHKLLPEAKAESLAR
AEAVFHTLGEGILGLFPERVLEERVSGPLLEGLIALLLELREEARRAKDYEKSDLIRERLRALGVIVEDTKEGPRWRLER
>Mature_479_residues
GLVIYDTLARRKVPFEPAVPGHVGIYVCGPTVYADPHLGHARGPVVYDVLRRYLLHKGYKVRFVSNITDVGHLTDDADEG
EDKIVRRAKLERLEPMEVAEKYTWSYFDAMQALNVLRPSIAPRASGHIPEMLELTERLLARGVAYERKGSVYFRVRSFPE
YGKLSGKRLEELRAGARVEVREEKEDPLDFALWKAAEPGHIMRWKSPWGEGYPGWHIECTAMSLKYLGEGFDLHAGGIDL
QFPHHECEIAQAEAAGFRFARHWMHHNHVLLEGEKMAKSTGNLVLLHDLLEAHEPMALRFYLLQTHYRSPMDFTWEGLES
AKRGYGRLLHAYREVRGRKKTAPPGTTPELERALDALEKAFMEAIEDDLSTPEALAALFAFLPELHKLLPEAKAESLARA
EAVFHTLGEGILGLFPERVLEERVSGPLLEGLIALLLELREEARRAKDYEKSDLIRERLRALGVIVEDTKEGPRWRLER

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=523, Percent_Identity=31.9311663479924, Blast_Score=226, Evalue=4e-59,
Organism=Homo sapiens, GI21269877, Length=407, Percent_Identity=31.6953316953317, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI62240992, Length=407, Percent_Identity=31.6953316953317, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI303304987, Length=407, Percent_Identity=31.6953316953317, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI10835051, Length=407, Percent_Identity=31.6953316953317, Blast_Score=171, Evalue=1e-42,
Organism=Escherichia coli, GI1786737, Length=483, Percent_Identity=41.2008281573499, Blast_Score=342, Evalue=2e-95,
Organism=Caenorhabditis elegans, GI17509795, Length=246, Percent_Identity=33.739837398374, Blast_Score=146, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI17509797, Length=246, Percent_Identity=33.739837398374, Blast_Score=146, Evalue=3e-35,
Organism=Saccharomyces cerevisiae, GI6324082, Length=314, Percent_Identity=31.2101910828025, Blast_Score=170, Evalue=5e-43,
Organism=Drosophila melanogaster, GI19922218, Length=521, Percent_Identity=29.7504798464491, Blast_Score=213, Evalue=2e-55,
Organism=Drosophila melanogaster, GI19922364, Length=242, Percent_Identity=35.1239669421488, Blast_Score=165, Evalue=5e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 54674; Mature: 54543

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLVIYDTLARRKVPFEPAVPGHVGIYVCGPTVYADPHLGHARGPVVYDVLRRYLLHKGY
CCEEEEEHHHHCCCCCCCCCCCCEEEEEECCEEECCCCCCCCCCCHHHHHHHHHHHHCCC
KVRFVSNITDVGHLTDDADEGEDKIVRRAKLERLEPMEVAEKYTWSYFDAMQALNVLRPS
EEEEECCCHHHCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCC
IAPRASGHIPEMLELTERLLARGVAYERKGSVYFRVRSFPEYGKLSGKRLEELRAGARVE
CCCCCCCCCHHHHHHHHHHHHHCCCEECCCCEEEEEECCCCCCCCCHHHHHHHHCCCCEE
VREEKEDPLDFALWKAAEPGHIMRWKSPWGEGYPGWHIECTAMSLKYLGEGFDLHAGGID
ECCCCCCCHHHHHHCCCCCCCEEEECCCCCCCCCCCEEEEHHHHHHHHCCCCEECCCCEE
LQFPHHECEIAQAEAAGFRFARHWMHHNHVLLEGEKMAKSTGNLVLLHDLLEAHEPMALR
EECCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHCCCCEEEEHHHHHHCCCHHHH
FYLLQTHYRSPMDFTWEGLESAKRGYGRLLHAYREVRGRKKTAPPGTTPELERALDALEK
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AFMEAIEDDLSTPEALAALFAFLPELHKLLPEAKAESLARAEAVFHTLGEGILGLFPERV
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
LEERVSGPLLEGLIALLLELREEARRAKDYEKSDLIRERLRALGVIVEDTKEGPRWRLER
HHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEECCCCCCCCCCCC
>Mature Secondary Structure 
GLVIYDTLARRKVPFEPAVPGHVGIYVCGPTVYADPHLGHARGPVVYDVLRRYLLHKGY
CEEEEEHHHHCCCCCCCCCCCCEEEEEECCEEECCCCCCCCCCCHHHHHHHHHHHHCCC
KVRFVSNITDVGHLTDDADEGEDKIVRRAKLERLEPMEVAEKYTWSYFDAMQALNVLRPS
EEEEECCCHHHCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCC
IAPRASGHIPEMLELTERLLARGVAYERKGSVYFRVRSFPEYGKLSGKRLEELRAGARVE
CCCCCCCCCHHHHHHHHHHHHHCCCEECCCCEEEEEECCCCCCCCCHHHHHHHHCCCCEE
VREEKEDPLDFALWKAAEPGHIMRWKSPWGEGYPGWHIECTAMSLKYLGEGFDLHAGGID
ECCCCCCCHHHHHHCCCCCCCEEEECCCCCCCCCCCEEEEHHHHHHHHCCCCEECCCCEE
LQFPHHECEIAQAEAAGFRFARHWMHHNHVLLEGEKMAKSTGNLVLLHDLLEAHEPMALR
EECCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHCCCCEEEEHHHHHHCCCHHHH
FYLLQTHYRSPMDFTWEGLESAKRGYGRLLHAYREVRGRKKTAPPGTTPELERALDALEK
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AFMEAIEDDLSTPEALAALFAFLPELHKLLPEAKAESLARAEAVFHTLGEGILGLFPERV
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
LEERVSGPLLEGLIALLLELREEARRAKDYEKSDLIRERLRALGVIVEDTKEGPRWRLER
HHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA