Click here to switch to the map view.

The map label for this gene is ccpA [H]

Identifier: 55980776

GI number: 55980776

Start: 770589

End: 771623

Strand: Reverse

Name: ccpA [H]

Synonym: TTHA0807

Alternate gene names: 55980776

Gene position: 771623-770589 (Counterclockwise)

Preceding gene: 55980782

Following gene: 55980775

Centisome position: 41.72

GC content: 71.5

Gene sequence:

>1035_bases
ATGAAGCGCAAAAAGCCCACCATCCACGACGTGGCGGCCAAGGCGGGCGTGGGCCTCGGCACCGTGAGCCGGGTCCTCAA
CGACCACCCCGCGGTGCGTCACGAGACCCGGGCCCGGGTGCTTAGGGCCATGGAGGAGCTGGGCTACGCGCCCAACCCCC
ACGCCCGCAGGATCGCGGGGGGGCGGAGCTACACGGTGAGCGTCCTCCTCCCCTTCGTGGCCACCGAGTTCTACCGCAGG
CTCGTGGAGGGGATTGAGGGCGTCCTCCTGGAGCAGCGCTACGACCTCGCCCTCTTCCCCATCCTCTCCCTGGCCCGGCT
TAAGCGCTACCTGGAGAACACCACCCTGGCCTACCTCACCGACGGCCTCATCCTCGCCTCCTACGACCTCACGGAGCGCT
TTGAGGAAGGAAGGTTGCCCACCGAGCGCCCCGTGGTGCTGGTGGACGCGCAAAACCCCCGCTACGACTCCGTCTACCTG
GACAACCGCCTGGGGGGAAGGCTCGCCGGGGCCTACCTCGCCCGCTTCCCGGGGCCCATCTTCGCCATCGCCGTGGAGGA
GGAGCCCGACCGGGCCTTCCGCCGCACGGTCTTCGCCGAACGGATGGCGGGCTTCCAGGAGGCCCTGAAGGAGGCCGGCC
GCCCCTTCTCCCCCGACCGGCTCTACATCACCCGCCACTCCCAGGAGGGGGGGCGCCTCGCCCTCCGCCACTTCCTGGAG
AAGGCCTCCCCGCCCCTCAACGTCTTCGCCGGGGCGGACCAGGTGGCCCTCGGGGTCCTGGAAGAAGCGGTAAGGCTCGG
CCTCACCCCCGGGAGGGACGTGCGGGTCCTGGGGTTTGACGGCCACCCCTTCGCCGAGGAGGCGGGGCTTTCCACCATCG
CCCAGCCCGTGGAGGCCATGGGGGCCCGGGCGGCCCAGCTCCTCCTGGAGAGGATGCGGGGCTACCAGGGCCCGCCCCGG
GAGGTGCGCTTTGAGCCCGTCCTCGTGGAGCGGGCCTCCACCGGCACCCCGCCCGCCGCCCTTTACGTGCCGTAA

Upstream 100 bases:

>100_bases
TAGGCCACGGGAGGATCTTACCAGGGCCTTGCCCCCTTGGGCGGGGTGGCCTATGCTAGGAGGTGGAAGTTTCCGTGAAC
CGCTTCCACCCGAGGGAACG

Downstream 100 bases:

>100_bases
ACTAGGCCCATGGGGTGGGAGCGGGTCGCCCACGGGGTGCGCTGGGTCATGGTCCTCCCGGTCCTGGGCCTGTTGCTGGG
TTCCTTCTACTTCGCCTTCC

Product: transcriptional regulator

Products: NA

Alternate protein names: Glucose-resistance amylase regulator [H]

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MKRKKPTIHDVAAKAGVGLGTVSRVLNDHPAVRHETRARVLRAMEELGYAPNPHARRIAGGRSYTVSVLLPFVATEFYRR
LVEGIEGVLLEQRYDLALFPILSLARLKRYLENTTLAYLTDGLILASYDLTERFEEGRLPTERPVVLVDAQNPRYDSVYL
DNRLGGRLAGAYLARFPGPIFAIAVEEEPDRAFRRTVFAERMAGFQEALKEAGRPFSPDRLYITRHSQEGGRLALRHFLE
KASPPLNVFAGADQVALGVLEEAVRLGLTPGRDVRVLGFDGHPFAEEAGLSTIAQPVEAMGARAAQLLLERMRGYQGPPR
EVRFEPVLVERASTGTPPAALYVP

Sequences:

>Translated_344_residues
MKRKKPTIHDVAAKAGVGLGTVSRVLNDHPAVRHETRARVLRAMEELGYAPNPHARRIAGGRSYTVSVLLPFVATEFYRR
LVEGIEGVLLEQRYDLALFPILSLARLKRYLENTTLAYLTDGLILASYDLTERFEEGRLPTERPVVLVDAQNPRYDSVYL
DNRLGGRLAGAYLARFPGPIFAIAVEEEPDRAFRRTVFAERMAGFQEALKEAGRPFSPDRLYITRHSQEGGRLALRHFLE
KASPPLNVFAGADQVALGVLEEAVRLGLTPGRDVRVLGFDGHPFAEEAGLSTIAQPVEAMGARAAQLLLERMRGYQGPPR
EVRFEPVLVERASTGTPPAALYVP
>Mature_344_residues
MKRKKPTIHDVAAKAGVGLGTVSRVLNDHPAVRHETRARVLRAMEELGYAPNPHARRIAGGRSYTVSVLLPFVATEFYRR
LVEGIEGVLLEQRYDLALFPILSLARLKRYLENTTLAYLTDGLILASYDLTERFEEGRLPTERPVVLVDAQNPRYDSVYL
DNRLGGRLAGAYLARFPGPIFAIAVEEEPDRAFRRTVFAERMAGFQEALKEAGRPFSPDRLYITRHSQEGGRLALRHFLE
KASPPLNVFAGADQVALGVLEEAVRLGLTPGRDVRVLGFDGHPFAEEAGLSTIAQPVEAMGARAAQLLLERMRGYQGPPR
EVRFEPVLVERASTGTPPAALYVP

Specific function: Transcriptional regulator involved in both the repression of carbohydrate utilization genes such as the alpha- amylase (AmyE) and the acetyl-coenzyme A synthetase (AcsA); and in the positive regulation of genes involved in excretion of excess carbon such

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787948, Length=349, Percent_Identity=28.3667621776504, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1790369, Length=346, Percent_Identity=30.0578034682081, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1790194, Length=345, Percent_Identity=30.7246376811594, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI48994940, Length=326, Percent_Identity=29.7546012269939, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1788474, Length=348, Percent_Identity=29.0229885057471, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790715, Length=325, Percent_Identity=26.1538461538462, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1789456, Length=334, Percent_Identity=25.748502994012, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787580, Length=321, Percent_Identity=23.98753894081, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1789202, Length=351, Percent_Identity=24.7863247863248, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1787906, Length=267, Percent_Identity=29.2134831460674, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006377
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 38134; Mature: 38134

Theoretical pI: Translated: 9.52; Mature: 9.52

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRKKPTIHDVAAKAGVGLGTVSRVLNDHPAVRHETRARVLRAMEELGYAPNPHARRIAG
CCCCCCCHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHCC
GRSYTVSVLLPFVATEFYRRLVEGIEGVLLEQRYDLALFPILSLARLKRYLENTTLAYLT
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHEEEE
DGLILASYDLTERFEEGRLPTERPVVLVDAQNPRYDSVYLDNRLGGRLAGAYLARFPGPI
CCEEEEECCHHHHHHHCCCCCCCCEEEEECCCCCCCEEEECCCCCHHHHHHHHHHCCCCE
FAIAVEEEPDRAFRRTVFAERMAGFQEALKEAGRPFSPDRLYITRHSQEGGRLALRHFLE
EEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHH
KASPPLNVFAGADQVALGVLEEAVRLGLTPGRDVRVLGFDGHPFAEEAGLSTIAQPVEAM
HCCCCCEEECCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHCHHHHHHHHHHH
GARAAQLLLERMRGYQGPPREVRFEPVLVERASTGTPPAALYVP
HHHHHHHHHHHHHCCCCCCCCEECCCEEEECCCCCCCCEEEECC
>Mature Secondary Structure
MKRKKPTIHDVAAKAGVGLGTVSRVLNDHPAVRHETRARVLRAMEELGYAPNPHARRIAG
CCCCCCCHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHCC
GRSYTVSVLLPFVATEFYRRLVEGIEGVLLEQRYDLALFPILSLARLKRYLENTTLAYLT
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHEEEE
DGLILASYDLTERFEEGRLPTERPVVLVDAQNPRYDSVYLDNRLGGRLAGAYLARFPGPI
CCEEEEECCHHHHHHHCCCCCCCCEEEEECCCCCCCEEEECCCCCHHHHHHHHHHCCCCE
FAIAVEEEPDRAFRRTVFAERMAGFQEALKEAGRPFSPDRLYITRHSQEGGRLALRHFLE
EEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHH
KASPPLNVFAGADQVALGVLEEAVRLGLTPGRDVRVLGFDGHPFAEEAGLSTIAQPVEAM
HCCCCCEEECCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHCHHHHHHHHHHH
GARAAQLLLERMRGYQGPPREVRFEPVLVERASTGTPPAALYVP
HHHHHHHHHHHHHCCCCCCCCEECCCEEEECCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1904524; 9387221; 9384377 [H]