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The map label for this gene is aroF [H]

Identifier: 55980769

GI number: 55980769

Start: 764983

End: 766017

Strand: Reverse

Name: aroF [H]

Synonym: TTHA0800

Alternate gene names: 55980769

Gene position: 766017-764983 (Counterclockwise)

Preceding gene: 55980770

Following gene: 55980768

Centisome position: 41.41

GC content: 69.76

Gene sequence:

>1035_bases
ATGCTGATCGTGATGAAGCGGGGGTACACGGAGGAGGAGCTTCAGGAGGTCGTCCGGGAAATAGAGAAGGTGGGCTACCG
GCCCCACGTCTCCCGGGGCGTGGAGACCACCCTGGTGGGGGCCATCGGCCGGGGGCCCACCCCCGAGCTCATGGAGCACT
TCCGGGCCCTGCCGGGAGTGGCCGAGGTCATCCCCATCTCCAAGCCCTGGAAGCTCGCAAGCCTCGAGGTCCAGCCCTTC
CCCACGGTCCTGGAGTTCCCCACGGGGAAGACGGGGGGCGGCCACGTGATGGTGGCGGCGGGGCCTTGCGGGGTGGAGTC
CCGGGAGCAGACCCTGAGGGCCGCCCACTACGTGAAGGCCCACGGGGCCCACATGCTCCGGGGGGGCGCTTTCAAACCCC
GCACGAGCCCCTACGCCTTCCAGGGCCTGGGCCTCGAGGGCCTGAAGATCCTCGCCGAGGCCAAGAGGGAGACGGGCCTC
CCCATCGTCACCGAGGTCCTCTCCCCGGAGCAGGTGGAGCTCGTGGCCGAGTACGCCGACGTCCTCCAGATCGGGGCGCG
GAACGCCCAGAACTTTCCCCTGCTCCAGGCGGTGGGGGAGGCGGGAAAGCCCGTCCTCCTCAAGCGGGGGATGAGCATGA
CCCTGGAAGAGTTCCTCATGAGCGCGGAGTACATCCTCTCCCGGGGCAACATGCGGGTGATCCTCGTGGAGCGGGGCATC
CGCACCTTTGAGAAGGCCACCCGCTTCACCCTAGACGTCGCCGCCGTGCCCGTCCTCAAGAGCTGGACCCACCTCCCCGT
CTGGATAGACCCCTCCCACCCGGCGGGCAAGAGGGACTGGGTCATCCCCTTGGCCCTGGCGGGGCTCGCCGCGGGAGCGG
ACGGCCTCATCGTGGAGACCCACCCCGAGCCGGAAAAGGCCCTCTCCGACGCCGCCCAGCAGCTCCACGAGCACGAGTTC
GCCGAGCTCATGGACAAGGTGCGCCGCCTGGTGGCCGCCCTGGACAAGACCCTCGCCGCCCCCGTCCTGGGATGA

Upstream 100 bases:

>100_bases
CTTTTATTACCCCGCCGGGGGCGCCCTGCGGTCCGCGTAGGCCATACCGCGAAAAGGGCGCCCCCTAAAGGGGGCGCCCA
AGGTTTTTGGGAGGGAAGCC

Downstream 100 bases:

>100_bases
AGCCCCTCTTCGGCAAAGTCGGGGTCTTCGGCGTGGGCCTTCTGGGCGGGAGCGTGGCCCTGGGGATTAAGGAGCGCTTC
CTCGCCGAGGAGGTCCACGC

Product: 3-deoxy-7-phosphoheptulonate synthase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MLIVMKRGYTEEELQEVVREIEKVGYRPHVSRGVETTLVGAIGRGPTPELMEHFRALPGVAEVIPISKPWKLASLEVQPF
PTVLEFPTGKTGGGHVMVAAGPCGVESREQTLRAAHYVKAHGAHMLRGGAFKPRTSPYAFQGLGLEGLKILAEAKRETGL
PIVTEVLSPEQVELVAEYADVLQIGARNAQNFPLLQAVGEAGKPVLLKRGMSMTLEEFLMSAEYILSRGNMRVILVERGI
RTFEKATRFTLDVAAVPVLKSWTHLPVWIDPSHPAGKRDWVIPLALAGLAAGADGLIVETHPEPEKALSDAAQQLHEHEF
AELMDKVRRLVAALDKTLAAPVLG

Sequences:

>Translated_344_residues
MLIVMKRGYTEEELQEVVREIEKVGYRPHVSRGVETTLVGAIGRGPTPELMEHFRALPGVAEVIPISKPWKLASLEVQPF
PTVLEFPTGKTGGGHVMVAAGPCGVESREQTLRAAHYVKAHGAHMLRGGAFKPRTSPYAFQGLGLEGLKILAEAKRETGL
PIVTEVLSPEQVELVAEYADVLQIGARNAQNFPLLQAVGEAGKPVLLKRGMSMTLEEFLMSAEYILSRGNMRVILVERGI
RTFEKATRFTLDVAAVPVLKSWTHLPVWIDPSHPAGKRDWVIPLALAGLAAGADGLIVETHPEPEKALSDAAQQLHEHEF
AELMDKVRRLVAALDKTLAAPVLG
>Mature_344_residues
MLIVMKRGYTEEELQEVVREIEKVGYRPHVSRGVETTLVGAIGRGPTPELMEHFRALPGVAEVIPISKPWKLASLEVQPF
PTVLEFPTGKTGGGHVMVAAGPCGVESREQTLRAAHYVKAHGAHMLRGGAFKPRTSPYAFQGLGLEGLKILAEAKRETGL
PIVTEVLSPEQVELVAEYADVLQIGARNAQNFPLLQAVGEAGKPVLLKRGMSMTLEEFLMSAEYILSRGNMRVILVERGI
RTFEKATRFTLDVAAVPVLKSWTHLPVWIDPSHPAGKRDWVIPLALAGLAAGADGLIVETHPEPEKALSDAAQQLHEHEF
AELMDKVRRLVAALDKTLAAPVLG

Specific function: Catalyzes the condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG2876

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787466, Length=230, Percent_Identity=30, Blast_Score=88, Evalue=7e-19,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006268 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 37449; Mature: 37449

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIVMKRGYTEEELQEVVREIEKVGYRPHVSRGVETTLVGAIGRGPTPELMEHFRALPGV
CEEEEECCCCHHHHHHHHHHHHHCCCCCCHHCCCHHHHHHHCCCCCCHHHHHHHHHCCCH
AEVIPISKPWKLASLEVQPFPTVLEFPTGKTGGGHVMVAAGPCGVESREQTLRAAHYVKA
HHHCCCCCCCEEEEEEECCCCCEEECCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHH
HGAHMLRGGAFKPRTSPYAFQGLGLEGLKILAEAKRETGLPIVTEVLSPEQVELVAEYAD
CCCHHHCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHH
VLQIGARNAQNFPLLQAVGEAGKPVLLKRGMSMTLEEFLMSAEYILSRGNMRVILVERGI
HHHHHCCCCCCCHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCH
RTFEKATRFTLDVAAVPVLKSWTHLPVWIDPSHPAGKRDWVIPLALAGLAAGADGLIVET
HHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHHHCCCCCEEEEC
HPEPEKALSDAAQQLHEHEFAELMDKVRRLVAALDKTLAAPVLG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLIVMKRGYTEEELQEVVREIEKVGYRPHVSRGVETTLVGAIGRGPTPELMEHFRALPGV
CEEEEECCCCHHHHHHHHHHHHHCCCCCCHHCCCHHHHHHHCCCCCCHHHHHHHHHCCCH
AEVIPISKPWKLASLEVQPFPTVLEFPTGKTGGGHVMVAAGPCGVESREQTLRAAHYVKA
HHHCCCCCCCEEEEEEECCCCCEEECCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHH
HGAHMLRGGAFKPRTSPYAFQGLGLEGLKILAEAKRETGLPIVTEVLSPEQVELVAEYAD
CCCHHHCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHH
VLQIGARNAQNFPLLQAVGEAGKPVLLKRGMSMTLEEFLMSAEYILSRGNMRVILVERGI
HHHHHCCCCCCCHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCH
RTFEKATRFTLDVAAVPVLKSWTHLPVWIDPSHPAGKRDWVIPLALAGLAAGADGLIVET
HHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHHHCCCCCEEEEC
HPEPEKALSDAAQQLHEHEFAELMDKVRRLVAALDKTLAAPVLG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571; 12743122 [H]