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The map label for this gene is lmxE [H]

Identifier: 54295350

GI number: 54295350

Start: 2777034

End: 2778188

Strand: Reverse

Name: lmxE [H]

Synonym: lpl2435

Alternate gene names: 54295350

Gene position: 2778188-2777034 (Counterclockwise)

Preceding gene: 54295351

Following gene: 54295349

Centisome position: 83.04

GC content: 41.56

Gene sequence:

>1155_bases
ATGAACTCTCAAAATAAACAAAATTTAGTTAAAACCGTAGCAATTGTATTTTTTGGTATTGTCTTTGTTTATTTAGTATA
TGACCATTTTACAAGAGCCCAGGTAGCAACCCCAGCACCACCAGTTGTGATCGTTCAAAAGCCCAAATTAATGAAAATGG
GACAGTACGTTACCCAGACAGGCAATACAGTAGCATTTCAATCGGTAGATTTGGTGGCACGGATTGAAGGTTATTTGGAT
GCCATAAAATTTACTGACGGCGCTTTTGTCAAAAAAAATCAGGAATTATTTATTATTGAACCCGAGCCCTATCTTGAGCA
ACTGCGTGCTGCTGAAGCCAAGGTAGCAGCTCAAAAAGCAAATTATGCCTATGCCAAATCAGAGTATGCCAGACAGCAAC
GCATGTATAAACAAAATGCCACGTCTCTTAACAGTGTTGAAAAATGGAAAGCAAAAGTTGAAGAAGCACAGGCGGAAGTG
GATAAATCGGAAGCTGATGCTACAAACGCCGCAATTACATATGGTTATACCCACGTTTCGGCTCCTTTCGATGGGCGGAT
GGGAAGACATTTAGTCGATGTGGGTAATTTGGTTGGGCACGGTGCCGCAACGGATTTGGCTACCATAGAACAAATCGACC
CTATTTACGTTTATTTTAATTTAAATGAACTGGATTTAATCAGGATTAGAAATGCAGCACGCAAGAGAGGATACAAACCA
ATGGAATTGGTCAAAATCCCTGTTGAAGTGGCTTTGCAAGATGAAAAAGGATTTCCTCATAAGGGGACATTGGATTTTGT
AAATACTGGTTTAAACGCTTCAACTGGAACCATGGAGTTTCGTGCCTTGTTACCTAACAAGGGATATCCCCTGGTGCCTG
GTTTATTTGTGCAAGTCCGGGTACCGATATCTGAACCTTCTCCAAAATTAACAATACCTGACACCTCTGTTCAATACGAT
CAAATTGGCCCCTATGTCCTTGTGGTTGATAAAGACAATTATGTGCTTACCAAACGCGTGACACTTGGCGGGCTAGAAAA
TGGGGTAAGGGCTATTACTAAAGGTCTCGATGCTCAAGATAGTGTGATTGTTTCCGGGTTGCAAAATGCGACGCCCAATC
ATCAGGTTACGCCTAAAACTGAGCAACCTGAGTAA

Upstream 100 bases:

>100_bases
GTACTAATTGGGGTAGTTTATTGAAGCAAGAAAATCATTTGCCTCCAGACTCTAACGGACAACGAATGAAACAACTATAT
TTACCAACCTGGTGATGAGA

Downstream 100 bases:

>100_bases
GTATGGCCAAAAAATTGTAAGAATTTAAGACCCTTTATTCAGGGAGCGAAACAACTGAAATGATTTCCAAATTTTTTATT
GAAAGACCCGTTCTGGCCAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MNSQNKQNLVKTVAIVFFGIVFVYLVYDHFTRAQVATPAPPVVIVQKPKLMKMGQYVTQTGNTVAFQSVDLVARIEGYLD
AIKFTDGAFVKKNQELFIIEPEPYLEQLRAAEAKVAAQKANYAYAKSEYARQQRMYKQNATSLNSVEKWKAKVEEAQAEV
DKSEADATNAAITYGYTHVSAPFDGRMGRHLVDVGNLVGHGAATDLATIEQIDPIYVYFNLNELDLIRIRNAARKRGYKP
MELVKIPVEVALQDEKGFPHKGTLDFVNTGLNASTGTMEFRALLPNKGYPLVPGLFVQVRVPISEPSPKLTIPDTSVQYD
QIGPYVLVVDKDNYVLTKRVTLGGLENGVRAITKGLDAQDSVIVSGLQNATPNHQVTPKTEQPE

Sequences:

>Translated_384_residues
MNSQNKQNLVKTVAIVFFGIVFVYLVYDHFTRAQVATPAPPVVIVQKPKLMKMGQYVTQTGNTVAFQSVDLVARIEGYLD
AIKFTDGAFVKKNQELFIIEPEPYLEQLRAAEAKVAAQKANYAYAKSEYARQQRMYKQNATSLNSVEKWKAKVEEAQAEV
DKSEADATNAAITYGYTHVSAPFDGRMGRHLVDVGNLVGHGAATDLATIEQIDPIYVYFNLNELDLIRIRNAARKRGYKP
MELVKIPVEVALQDEKGFPHKGTLDFVNTGLNASTGTMEFRALLPNKGYPLVPGLFVQVRVPISEPSPKLTIPDTSVQYD
QIGPYVLVVDKDNYVLTKRVTLGGLENGVRAITKGLDAQDSVIVSGLQNATPNHQVTPKTEQPE
>Mature_384_residues
MNSQNKQNLVKTVAIVFFGIVFVYLVYDHFTRAQVATPAPPVVIVQKPKLMKMGQYVTQTGNTVAFQSVDLVARIEGYLD
AIKFTDGAFVKKNQELFIIEPEPYLEQLRAAEAKVAAQKANYAYAKSEYARQQRMYKQNATSLNSVEKWKAKVEEAQAEV
DKSEADATNAAITYGYTHVSAPFDGRMGRHLVDVGNLVGHGAATDLATIEQIDPIYVYFNLNELDLIRIRNAARKRGYKP
MELVKIPVEVALQDEKGFPHKGTLDFVNTGLNASTGTMEFRALLPNKGYPLVPGLFVQVRVPISEPSPKLTIPDTSVQYD
QIGPYVLVVDKDNYVLTKRVTLGGLENGVRAITKGLDAQDSVIVSGLQNATPNHQVTPKTEQPE

Specific function: May contribute to resistance to some drugs, such as deoxycholate, sodium dodecyl sulfate and nalidixic acid, in the absence of BepD and BepE [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1789665, Length=338, Percent_Identity=30.1775147928994, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1789929, Length=361, Percent_Identity=26.5927977839335, Blast_Score=137, Evalue=8e-34,
Organism=Escherichia coli, GI87082036, Length=322, Percent_Identity=29.1925465838509, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1786668, Length=317, Percent_Identity=29.9684542586751, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI87081796, Length=379, Percent_Identity=24.0105540897098, Blast_Score=68, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 42507; Mature: 42507

Theoretical pI: Translated: 8.52; Mature: 8.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSQNKQNLVKTVAIVFFGIVFVYLVYDHFTRAQVATPAPPVVIVQKPKLMKMGQYVTQT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEECCCCCCEEEEECCCHHHHHHHHHHC
GNTVAFQSVDLVARIEGYLDAIKFTDGAFVKKNQELFIIEPEPYLEQLRAAEAKVAAQKA
CCEEEEEHHHHHHHHHHHHHHHEECCCCEEECCCCEEEECCCHHHHHHHHHHHHHHHHHC
NYAYAKSEYARQQRMYKQNATSLNSVEKWKAKVEEAQAEVDKSEADATNAAITYGYTHVS
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHCCCCCCEEEECEEEEC
APFDGRMGRHLVDVGNLVGHGAATDLATIEQIDPIYVYFNLNELDLIRIRNAARKRGYKP
CCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCEEEEEEECCCEEEHHHHHHHHHCCCCC
MELVKIPVEVALQDEKGFPHKGTLDFVNTGLNASTGTMEFRALLPNKGYPLVPGLFVQVR
HHEEEECEEEEEECCCCCCCCCCHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCEEEEEE
VPISEPSPKLTIPDTSVQYDQIGPYVLVVDKDNYVLTKRVTLGGLENGVRAITKGLDAQD
EECCCCCCEEECCCCCCCHHCCCCEEEEEECCCEEEEEEEEECCHHHHHHHHHHCCCCCC
SVIVSGLQNATPNHQVTPKTEQPE
HHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNSQNKQNLVKTVAIVFFGIVFVYLVYDHFTRAQVATPAPPVVIVQKPKLMKMGQYVTQT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEECCCCCCEEEEECCCHHHHHHHHHHC
GNTVAFQSVDLVARIEGYLDAIKFTDGAFVKKNQELFIIEPEPYLEQLRAAEAKVAAQKA
CCEEEEEHHHHHHHHHHHHHHHEECCCCEEECCCCEEEECCCHHHHHHHHHHHHHHHHHC
NYAYAKSEYARQQRMYKQNATSLNSVEKWKAKVEEAQAEVDKSEADATNAAITYGYTHVS
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHCCCCCCEEEECEEEEC
APFDGRMGRHLVDVGNLVGHGAATDLATIEQIDPIYVYFNLNELDLIRIRNAARKRGYKP
CCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCEEEEEEECCCEEEHHHHHHHHHCCCCC
MELVKIPVEVALQDEKGFPHKGTLDFVNTGLNASTGTMEFRALLPNKGYPLVPGLFVQVR
HHEEEECEEEEEECCCCCCCCCCHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCEEEEEE
VPISEPSPKLTIPDTSVQYDQIGPYVLVVDKDNYVLTKRVTLGGLENGVRAITKGLDAQD
EECCCCCCEEECCCCCCCHHCCCCEEEEEECCCEEEEEEEEECCHHHHHHHHHHCCCCCC
SVIVSGLQNATPNHQVTPKTEQPE
HHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12271122 [H]