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The map label for this gene is acdA [H]

Identifier: 54294833

GI number: 54294833

Start: 2143731

End: 2144858

Strand: Reverse

Name: acdA [H]

Synonym: lpl1911

Alternate gene names: 54294833

Gene position: 2144858-2143731 (Counterclockwise)

Preceding gene: 54294834

Following gene: 54294832

Centisome position: 64.11

GC content: 38.74

Gene sequence:

>1128_bases
TTGCCAAATTACCAGCCTCAATACGTGAAGCAACAGCGGCTATTTAACCAATTTATAGAAGATTGCCTTCACCCCCATGC
AAAAATTTTTGATAAGGAACAAAACATTCCGCGCGACTTTTTTTATACATTAGCCCAAAATGGTTTTTTGGGCGCTGGTA
TTCCCAAACAATTTGGCGGGCAGCAATGGGATGAATTGACCATTGGTATCATGCATGAATCCTTCGCTAAAGAATTTTGT
TCTTTGGCAAATATCCTAACAGTATTGGGTATGGTGAGTAAGTCACTTTTGCAATTTGGTTCAAAAGCTCAGAAGCAAAT
CTGGTTGCCACGGATTGCCTCAGGAGAAACTTTAGCTGCATTGGCTTTAACTGAATCTAATATCGGTAGTGATTTGGAGC
ATGTTGAAACCCAGTTGCTGGATGCAGGTGATGAATTCATTTTAAAAGGAAGTAAAAAATACATTACCTTAGGGCAAATA
GCGGATTTGTTTTTAGTTTTAGCAAATTGCCAAGGCCAACTGACTGCGGTTTTAGTTGAAAAGGACACGTCAGGCTTAAT
TATTACACCCATGTCTAATTTTTTAGGATTACGTTCTAATATGTTGGCAGAAATTTTTTTTGATAATTGCCGAATTCCTA
AAACAAATCTGTTGGGTAGTATCGGTATCGGCTTTAACTGTATTATTCAAACTGCTTTAGATGAAGGACGTTATACAACA
GCGTATGGATGTGTTGGTTTAGGGCAAGCTTGCCTGGATGCGGCTCTTGGCTATACTCAAAAAAGAAAACAATTCGATCG
CAGATTAGACGAACATCAGCTCATTCAAAAAATGATAGCTGAAATGGTGGTACAGGTCAAAGCGGCCCGGGAATTGTGTT
TTTATGCCGGAGAACTTAGACAGCAAAAAAATCCAGCATACATAGCTGAAACATTAATTGCAAAATACGCGGCTTCAAAA
ATGGTTGTTTTTGTATCTAACCATGCTTTGCAAATATTTGGTGCAGCTGGCTTTGAAGACACTTACCCTGTTGAGCGATA
TTATAGAGATGCCAAGGTAATGGAGATCATTGAAGGTACCTCACAAATGCACGAGATACTCATTTCAAAGCTTTGCAACA
ATAAATAG

Upstream 100 bases:

>100_bases
AACAAAAAAGGGATTTTATCAGTATGAATAAGGGGTAGTTTACCATTCGCTATTTCAACCCGGATGGTTAAATTGTAAAC
AAACACCAGGGAGAGCAATT

Downstream 100 bases:

>100_bases
AGGATATTATTAAACAATGCGATCCCCTGATCAGTACACGACAATTTGCTCCTTATTTGAGGAGAAGGTAAAGCAATGCC
TGGAAAATACAGCGGTTTAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MPNYQPQYVKQQRLFNQFIEDCLHPHAKIFDKEQNIPRDFFYTLAQNGFLGAGIPKQFGGQQWDELTIGIMHESFAKEFC
SLANILTVLGMVSKSLLQFGSKAQKQIWLPRIASGETLAALALTESNIGSDLEHVETQLLDAGDEFILKGSKKYITLGQI
ADLFLVLANCQGQLTAVLVEKDTSGLIITPMSNFLGLRSNMLAEIFFDNCRIPKTNLLGSIGIGFNCIIQTALDEGRYTT
AYGCVGLGQACLDAALGYTQKRKQFDRRLDEHQLIQKMIAEMVVQVKAARELCFYAGELRQQKNPAYIAETLIAKYAASK
MVVFVSNHALQIFGAAGFEDTYPVERYYRDAKVMEIIEGTSQMHEILISKLCNNK

Sequences:

>Translated_375_residues
MPNYQPQYVKQQRLFNQFIEDCLHPHAKIFDKEQNIPRDFFYTLAQNGFLGAGIPKQFGGQQWDELTIGIMHESFAKEFC
SLANILTVLGMVSKSLLQFGSKAQKQIWLPRIASGETLAALALTESNIGSDLEHVETQLLDAGDEFILKGSKKYITLGQI
ADLFLVLANCQGQLTAVLVEKDTSGLIITPMSNFLGLRSNMLAEIFFDNCRIPKTNLLGSIGIGFNCIIQTALDEGRYTT
AYGCVGLGQACLDAALGYTQKRKQFDRRLDEHQLIQKMIAEMVVQVKAARELCFYAGELRQQKNPAYIAETLIAKYAASK
MVVFVSNHALQIFGAAGFEDTYPVERYYRDAKVMEIIEGTSQMHEILISKLCNNK
>Mature_374_residues
PNYQPQYVKQQRLFNQFIEDCLHPHAKIFDKEQNIPRDFFYTLAQNGFLGAGIPKQFGGQQWDELTIGIMHESFAKEFCS
LANILTVLGMVSKSLLQFGSKAQKQIWLPRIASGETLAALALTESNIGSDLEHVETQLLDAGDEFILKGSKKYITLGQIA
DLFLVLANCQGQLTAVLVEKDTSGLIITPMSNFLGLRSNMLAEIFFDNCRIPKTNLLGSIGIGFNCIIQTALDEGRYTTA
YGCVGLGQACLDAALGYTQKRKQFDRRLDEHQLIQKMIAEMVVQVKAARELCFYAGELRQQKNPAYIAETLIAKYAASKM
VVFVSNHALQIFGAAGFEDTYPVERYYRDAKVMEIIEGTSQMHEILISKLCNNK

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=358, Percent_Identity=35.195530726257, Blast_Score=210, Evalue=2e-54,
Organism=Homo sapiens, GI4501859, Length=360, Percent_Identity=32.2222222222222, Blast_Score=192, Evalue=4e-49,
Organism=Homo sapiens, GI187960098, Length=377, Percent_Identity=30.2387267904509, Blast_Score=162, Evalue=4e-40,
Organism=Homo sapiens, GI4557231, Length=377, Percent_Identity=30.2387267904509, Blast_Score=162, Evalue=4e-40,
Organism=Homo sapiens, GI21361497, Length=355, Percent_Identity=29.5774647887324, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI76496475, Length=383, Percent_Identity=27.4151436031332, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI4557235, Length=384, Percent_Identity=27.8645833333333, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI226958412, Length=383, Percent_Identity=29.5039164490862, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI7656849, Length=363, Percent_Identity=28.6501377410468, Blast_Score=158, Evalue=8e-39,
Organism=Homo sapiens, GI226958414, Length=349, Percent_Identity=29.7994269340974, Blast_Score=152, Evalue=5e-37,
Organism=Homo sapiens, GI4503943, Length=363, Percent_Identity=27.5482093663912, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI4501857, Length=374, Percent_Identity=26.4705882352941, Blast_Score=149, Evalue=6e-36,
Organism=Homo sapiens, GI7669494, Length=351, Percent_Identity=27.6353276353276, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI211971008, Length=289, Percent_Identity=27.681660899654, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI48976061, Length=289, Percent_Identity=27.681660899654, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI38505218, Length=284, Percent_Identity=27.112676056338, Blast_Score=98, Evalue=2e-20,
Organism=Escherichia coli, GI87081958, Length=340, Percent_Identity=25.5882352941176, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI1786223, Length=345, Percent_Identity=22.6086956521739, Blast_Score=99, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17506239, Length=365, Percent_Identity=30.958904109589, Blast_Score=192, Evalue=3e-49,
Organism=Caenorhabditis elegans, GI17508101, Length=363, Percent_Identity=30.5785123966942, Blast_Score=189, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI17534899, Length=363, Percent_Identity=32.5068870523416, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17569725, Length=369, Percent_Identity=32.2493224932249, Blast_Score=179, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI17570075, Length=363, Percent_Identity=32.5068870523416, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17538396, Length=367, Percent_Identity=30.5177111716621, Blast_Score=174, Evalue=5e-44,
Organism=Caenorhabditis elegans, GI17533517, Length=361, Percent_Identity=28.808864265928, Blast_Score=164, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI71985184, Length=351, Percent_Identity=28.2051282051282, Blast_Score=152, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI71990804, Length=280, Percent_Identity=30.3571428571429, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17505929, Length=376, Percent_Identity=26.8617021276596, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17551932, Length=375, Percent_Identity=26.6666666666667, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI71985192, Length=276, Percent_Identity=28.6231884057971, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI32563615, Length=242, Percent_Identity=30.1652892561983, Blast_Score=121, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI71982178, Length=258, Percent_Identity=29.0697674418605, Blast_Score=117, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI17534353, Length=382, Percent_Identity=24.0837696335079, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17531909, Length=238, Percent_Identity=28.1512605042017, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17562446, Length=292, Percent_Identity=26.027397260274, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17531913, Length=181, Percent_Identity=23.7569060773481, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21356377, Length=364, Percent_Identity=34.0659340659341, Blast_Score=207, Evalue=8e-54,
Organism=Drosophila melanogaster, GI24660351, Length=368, Percent_Identity=33.1521739130435, Blast_Score=192, Evalue=4e-49,
Organism=Drosophila melanogaster, GI24666513, Length=360, Percent_Identity=30.8333333333333, Blast_Score=179, Evalue=3e-45,
Organism=Drosophila melanogaster, GI24646207, Length=363, Percent_Identity=30.5785123966942, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI21355753, Length=371, Percent_Identity=31.5363881401617, Blast_Score=157, Evalue=8e-39,
Organism=Drosophila melanogaster, GI19920834, Length=366, Percent_Identity=28.6885245901639, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI281363737, Length=376, Percent_Identity=26.5957446808511, Blast_Score=142, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 41954; Mature: 41823

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNYQPQYVKQQRLFNQFIEDCLHPHAKIFDKEQNIPRDFFYTLAQNGFLGAGIPKQFGG
CCCCCHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCHHHCC
QQWDELTIGIMHESFAKEFCSLANILTVLGMVSKSLLQFGSKAQKQIWLPRIASGETLAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCEEE
LALTESNIGSDLEHVETQLLDAGDEFILKGSKKYITLGQIADLFLVLANCQGQLTAVLVE
EEEECCCCCCHHHHHHHHHHHCCCHHEEECCCCEEEHHHHHHHHHHHHCCCCCEEEEEEE
KDTSGLIITPMSNFLGLRSNMLAEIFFDNCRIPKTNLLGSIGIGFNCIIQTALDEGRYTT
ECCCCEEEECHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCHHHHHHHHHCCCCEEE
AYGCVGLGQACLDAALGYTQKRKQFDRRLDEHQLIQKMIAEMVVQVKAARELCFYAGELR
HHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQKNPAYIAETLIAKYAASKMVVFVSNHALQIFGAAGFEDTYPVERYYRDAKVMEIIEGT
HCCCHHHHHHHHHHHHHHCCEEEEEECCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
SQMHEILISKLCNNK
HHHHHHHHHHHHCCC
>Mature Secondary Structure 
PNYQPQYVKQQRLFNQFIEDCLHPHAKIFDKEQNIPRDFFYTLAQNGFLGAGIPKQFGG
CCCCHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCHHHCC
QQWDELTIGIMHESFAKEFCSLANILTVLGMVSKSLLQFGSKAQKQIWLPRIASGETLAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCEEE
LALTESNIGSDLEHVETQLLDAGDEFILKGSKKYITLGQIADLFLVLANCQGQLTAVLVE
EEEECCCCCCHHHHHHHHHHHCCCHHEEECCCCEEEHHHHHHHHHHHHCCCCCEEEEEEE
KDTSGLIITPMSNFLGLRSNMLAEIFFDNCRIPKTNLLGSIGIGFNCIIQTALDEGRYTT
ECCCCEEEECHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCHHHHHHHHHCCCCEEE
AYGCVGLGQACLDAALGYTQKRKQFDRRLDEHQLIQKMIAEMVVQVKAARELCFYAGELR
HHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQKNPAYIAETLIAKYAASKMVVFVSNHALQIFGAAGFEDTYPVERYYRDAKVMEIIEGT
HCCCHHHHHHHHHHHHHHCCEEEEEECCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
SQMHEILISKLCNNK
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]