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The map label for this gene is groES [H]

Identifier: 54293670

GI number: 54293670

Start: 811835

End: 812125

Strand: Direct

Name: groES [H]

Synonym: lpl0723

Alternate gene names: 54293670

Gene position: 811835-812125 (Clockwise)

Preceding gene: 54293667

Following gene: 54293671

Centisome position: 24.27

GC content: 42.96

Gene sequence:

>291_bases
ATGAAAATTCGTCCTTTACACGATCGCGTTGTTGTTCGTCGTATGGAAGAAGAGCGTACCACTGCTGGTGGTATTGTTAT
TCCAGATAGTGCTACCGAGAAACCTATGCGTGGTGAGATCATTGCTGTTGGCGCTGGCAAAGTATTGGAAAACGGTGATG
TTCGTGCTTTAGCAGTTAAAGTTGGTGATGTTGTATTGTTTGGCAAGTACTCTGGTACTGAAGTTAAAGTTGATGGAAAA
GAATTAGTTGTGATGCGCGAAGACGACATCATGGGTGTAATCGAGAAGTAA

Upstream 100 bases:

>100_bases
GTTTGTTTATTGTCCCCATATCGCTGTCATCGGTATTGTTTGCCCTAAGGAAAGCAATACTTAAATGATTTAAAGTTTAA
TTTAATCAGGAGAGAAAAGT

Downstream 100 bases:

>100_bases
TCTAATTGTTTAAAGGAGACAATGATAATGGCTAAAGAATTACGTTTTGGTGATGACGCTCGCCTACAAATGCTTGCTGG
TGTTAATGCATTAGCAGATG

Product: co-chaperonin GroES

Products: NA

Alternate protein names: GroES protein; Heat shock protein A; Protein Cpn10 [H]

Number of amino acids: Translated: 96; Mature: 96

Protein sequence:

>96_residues
MKIRPLHDRVVVRRMEEERTTAGGIVIPDSATEKPMRGEIIAVGAGKVLENGDVRALAVKVGDVVLFGKYSGTEVKVDGK
ELVVMREDDIMGVIEK

Sequences:

>Translated_96_residues
MKIRPLHDRVVVRRMEEERTTAGGIVIPDSATEKPMRGEIIAVGAGKVLENGDVRALAVKVGDVVLFGKYSGTEVKVDGK
ELVVMREDDIMGVIEK
>Mature_96_residues
MKIRPLHDRVVVRRMEEERTTAGGIVIPDSATEKPMRGEIIAVGAGKVLENGDVRALAVKVGDVVLFGKYSGTEVKVDGK
ELVVMREDDIMGVIEK

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter [H]

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family [H]

Homologues:

Organism=Homo sapiens, GI4504523, Length=91, Percent_Identity=40.6593406593407, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790585, Length=96, Percent_Identity=52.0833333333333, Blast_Score=101, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI17555568, Length=93, Percent_Identity=41.9354838709677, Blast_Score=77, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6324594, Length=95, Percent_Identity=36.8421052631579, Blast_Score=65, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21358317, Length=96, Percent_Identity=42.7083333333333, Blast_Score=70, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21356029, Length=97, Percent_Identity=40.2061855670103, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032 [H]

Pfam domain/function: PF00166 Cpn10 [H]

EC number: NA

Molecular weight: Translated: 10475; Mature: 10475

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIRPLHDRVVVRRMEEERTTAGGIVIPDSATEKPMRGEIIAVGAGKVLENGDVRALAVK
CCCCCCHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCEEEEECCCEECCCCEEEEEEE
VGDVVLFGKYSGTEVKVDGKELVVMREDDIMGVIEK
ECCEEEEECCCCCEEEECCCEEEEEECCCEEEEECC
>Mature Secondary Structure
MKIRPLHDRVVVRRMEEERTTAGGIVIPDSATEKPMRGEIIAVGAGKVLENGDVRALAVK
CCCCCCHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCEEEEECCCEECCCCEEEEEEE
VGDVVLFGKYSGTEVKVDGKELVVMREDDIMGVIEK
ECCEEEEECCCCCEEEECCCEEEEEECCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1672279 [H]