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The map label for this gene is fabG [H]

Identifier: 54293211

GI number: 54293211

Start: 288736

End: 289434

Strand: Direct

Name: fabG [H]

Synonym: lpl0259

Alternate gene names: 54293211

Gene position: 288736-289434 (Clockwise)

Preceding gene: 54293207

Following gene: 54293212

Centisome position: 8.63

GC content: 44.06

Gene sequence:

>699_bases
ATGGCTCGCTACCTGGTAATTGCTGCAAGCAGTGCTATCGGACAATCCGTGACAACCCTTTTAAAAAATCGTGGTGATAC
TGTTTTTACCACAGCACGAGATAATCATAAGATAAGCCCTGATTTTCAACTGGATGCCACTCATTTTGATGCGGTTTTAG
ATGTTTTTCGCCAAGCAGGTCCTCTTGATGGTGTAGTGAATTGTGCAGGTTCACTACTTCTGAAAAATGCTCACAGCACC
AGTTTTGATGAATTTCAAGTCGCGATAAATGCGTCACTCACTACTTCTTTTGCTACCATTCGAGCTGCCGGTTTAACGAT
GAATCAAGGAGGTTCTGTTGTATTGATATCATCAGCCGCAGCTTTGGTAGGTTTGGCCAATCATGAAGCCATTGCGGCGG
CCAAAGCGGGTATCATTGGTTTGGCTCAATCTGCTGCTGCCACTTATGCTTCAAACAATTTAAGAGTGAATGTCGTGGCT
CCTGGAATGGTTAATAGCCCGCTGACCTCATCGTTATTAAGCAATCAGTTAGTTTTGAATGCATCAAAGACAATGCATGC
TTTAGGGCGAATTGGTGTTCCGGAAGATATTGCCCACGCAATTGTGTTTTTGCTTAATCCGAACAACAGCTGGATCACAG
GGCAAGTGATTGCTGTTGATGGCGGATTAAGCCGAGTTCGGCCCAAGATGAAAATTTAA

Upstream 100 bases:

>100_bases
TAACTTATCCAATGGCATGGGATGTCCGTATAATGAATATTGAAGTTTCCAAGCTAATCCATCATAGTAGGTATTTTTAT
ACTAATGCAAGAAGAATGAT

Downstream 100 bases:

>100_bases
TGAAACTATAATTCTTATGACGACACTGTGTTTTATATTAGGCGATCAACTCAATGAAACAATCGCCTCACTTGCGGCAA
TTAATAAACAGAAGGACATT

Product: hypothetical protein

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MARYLVIAASSAIGQSVTTLLKNRGDTVFTTARDNHKISPDFQLDATHFDAVLDVFRQAGPLDGVVNCAGSLLLKNAHST
SFDEFQVAINASLTTSFATIRAAGLTMNQGGSVVLISSAAALVGLANHEAIAAAKAGIIGLAQSAAATYASNNLRVNVVA
PGMVNSPLTSSLLSNQLVLNASKTMHALGRIGVPEDIAHAIVFLLNPNNSWITGQVIAVDGGLSRVRPKMKI

Sequences:

>Translated_232_residues
MARYLVIAASSAIGQSVTTLLKNRGDTVFTTARDNHKISPDFQLDATHFDAVLDVFRQAGPLDGVVNCAGSLLLKNAHST
SFDEFQVAINASLTTSFATIRAAGLTMNQGGSVVLISSAAALVGLANHEAIAAAKAGIIGLAQSAAATYASNNLRVNVVA
PGMVNSPLTSSLLSNQLVLNASKTMHALGRIGVPEDIAHAIVFLLNPNNSWITGQVIAVDGGLSRVRPKMKI
>Mature_231_residues
ARYLVIAASSAIGQSVTTLLKNRGDTVFTTARDNHKISPDFQLDATHFDAVLDVFRQAGPLDGVVNCAGSLLLKNAHSTS
FDEFQVAINASLTTSFATIRAAGLTMNQGGSVVLISSAAALVGLANHEAIAAAKAGIIGLAQSAAATYASNNLRVNVVAP
GMVNSPLTSSLLSNQLVLNASKTMHALGRIGVPEDIAHAIVFLLNPNNSWITGQVIAVDGGLSRVRPKMKI

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=239, Percent_Identity=30.9623430962343, Blast_Score=95, Evalue=7e-20,
Organism=Homo sapiens, GI15277342, Length=247, Percent_Identity=30.3643724696356, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI19923817, Length=180, Percent_Identity=33.3333333333333, Blast_Score=81, Evalue=7e-16,
Organism=Homo sapiens, GI4758504, Length=183, Percent_Identity=30.0546448087432, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI10190704, Length=195, Percent_Identity=27.6923076923077, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI32483357, Length=113, Percent_Identity=33.6283185840708, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI5031737, Length=119, Percent_Identity=32.7731092436975, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI66933014, Length=192, Percent_Identity=26.0416666666667, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI126723750, Length=113, Percent_Identity=30.9734513274336, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1787335, Length=240, Percent_Identity=29.5833333333333, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI2367365, Length=182, Percent_Identity=29.1208791208791, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1788459, Length=252, Percent_Identity=25.7936507936508, Blast_Score=70, Evalue=9e-14,
Organism=Escherichia coli, GI1789208, Length=170, Percent_Identity=27.6470588235294, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1786812, Length=174, Percent_Identity=31.0344827586207, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI87082100, Length=175, Percent_Identity=27.4285714285714, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17555706, Length=187, Percent_Identity=33.6898395721925, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI25147288, Length=239, Percent_Identity=28.0334728033473, Blast_Score=78, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71994600, Length=185, Percent_Identity=28.6486486486486, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17560676, Length=113, Percent_Identity=31.858407079646, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17538182, Length=186, Percent_Identity=27.4193548387097, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71994604, Length=228, Percent_Identity=25.4385964912281, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17561402, Length=120, Percent_Identity=30.8333333333333, Blast_Score=64, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=197, Percent_Identity=26.3959390862944, Blast_Score=71, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24639444, Length=245, Percent_Identity=29.3877551020408, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24644337, Length=178, Percent_Identity=32.5842696629214, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24643142, Length=231, Percent_Identity=26.8398268398268, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21355319, Length=120, Percent_Identity=30, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI17737361, Length=185, Percent_Identity=30.8108108108108, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24644339, Length=181, Percent_Identity=29.2817679558011, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI28571526, Length=248, Percent_Identity=26.2096774193548, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 24073; Mature: 23942

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARYLVIAASSAIGQSVTTLLKNRGDTVFTTARDNHKISPDFQLDATHFDAVLDVFRQAG
CCEEEEEEECCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEECHHHHHHHHHHHHHCC
PLDGVVNCAGSLLLKNAHSTSFDEFQVAINASLTTSFATIRAAGLTMNQGGSVVLISSAA
CCCHHHHHHHHHEEECCCCCCCCEEEEEEECCHHHHHHEEEEECEEECCCCCEEEEECCC
ALVGLANHEAIAAAKAGIIGLAQSAAATYASNNLRVNVVAPGMVNSPLTSSLLSNQLVLN
EEEEECCCHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHCCEEEEE
ASKTMHALGRIGVPEDIAHAIVFLLNPNNSWITGQVIAVDGGLSRVRPKMKI
CHHHHHHHHCCCCCHHHHEEEEEEECCCCCEEEEEEEEEECCHHHCCCCCCC
>Mature Secondary Structure 
ARYLVIAASSAIGQSVTTLLKNRGDTVFTTARDNHKISPDFQLDATHFDAVLDVFRQAG
CEEEEEEECCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEECHHHHHHHHHHHHHCC
PLDGVVNCAGSLLLKNAHSTSFDEFQVAINASLTTSFATIRAAGLTMNQGGSVVLISSAA
CCCHHHHHHHHHEEECCCCCCCCEEEEEEECCHHHHHHEEEEECEEECCCCCEEEEECCC
ALVGLANHEAIAAAKAGIIGLAQSAAATYASNNLRVNVVAPGMVNSPLTSSLLSNQLVLN
EEEEECCCHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHCCEEEEE
ASKTMHALGRIGVPEDIAHAIVFLLNPNNSWITGQVIAVDGGLSRVRPKMKI
CHHHHHHHHCCCCCHHHHEEEEEEECCCCCEEEEEEEEEECCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]