Click here to switch to the map view.

The map label for this gene is dnaC [H]

Identifier: 52788015

GI number: 52788015

Start: 4190140

End: 4191504

Strand: Reverse

Name: dnaC [H]

Synonym: BLi04343

Alternate gene names: 52788015

Gene position: 4191504-4190140 (Counterclockwise)

Preceding gene: 52788017

Following gene: 52788013

Centisome position: 99.26

GC content: 49.82

Gene sequence:

>1365_bases
ATGACAGATCTTCTGAATGACAGGCTGCCGCCGCAAAATATCGAAGCCGAACAGGCCGTGTTAGGTGCTGTTTTTTTAGA
ACCATCAGCTTTAACTTTGGCGTCAGAAGTCTTGATTCCAGATGATTTTTACAGAATGTCGCACCAAAAAATATTTAACG
CCATGCTTGTTCTTGGAGACCGCGGCGAGCCTGTAGACCTGGTGACGGTGACATCAGAGCTTGCGAACACGGACCTTTTG
GAAGAGGTTGGCGGCATTTCTTATTTGACGGATATTGCAAATTCTGTGCCGACTGCGGCTAATATAGAGTATTATGCAAA
AATCGTGGAAGAAAAATCGATTCTCCGCCGCTTGATCCGTACAGCAACGACGATTGCCCAAGACGGATATACAAGGGAGG
ATGAAGTCGAAGACCTCTTAAGCGAAGCAGAAAAAACGATTATGGAAGTCGCCCAGCGCAAAAACTCCGGGGCCTTTCAA
AATATTAAAGATGTTCTCGTTCAAACCTACGATAATATTGAACAGCTCCACAACAGAAAAGGGGACATCACCGGGATTCC
GACAGGTTTTACCGAGCTTGACAGGATGACGGCGGGCTTTCAAAGAAACGATTTGATCATCGTAGCCGCCCGTCCGTCAG
TCGGCAAAACCGCTTTTGCCTTAAACATCGCCCAAAACGTGGCGACGAAAACCGATGAAAGCGTCGCGATCTTCAGCCTT
GAGATGGGCGCCGAGCAGCTGGTCATGCGGATGCTCTGTGCGGAAGGCAACATCAACGCCCAGAATCTCCGGACCGGAAA
CCTGACGGAAGAGGATTGGGGCAAGCTGACAATGGCGATGGGAAGCTTATCAAACAGCGGAATTTTCATCGATGACACAC
CGGGAATCCGCGTCAGCGAAATCCGTTCCAAGTGCAGACGTTTAAAGCAGGAGAACGGCCTCGGCATGATTTTGATCGAC
TACCTGCAGCTGATCCAAGGAAGCGGCAGATCAAGTGACAACCGCCAGCAGGAAGTATCGGAAATATCCCGTGCGCTGAA
AGCGCTGGCGAGGGAGCTTGAAGTTCCGGTCATCGCCCTTTCACAGCTTTCCCGGGGCGTCGAACAGCGCCAGGATAAGC
GTCCGATGATGTCGGACATCCGGGAATCGGGAAGTATCGAGCAGGACGCCGATATCGTTGCGTTCCTGTACCGTGATGAT
TACTATGACAAAGAATCTGAGAATAAAAACATCATTGAAATCATTATTGCAAAACAAAGGAACGGCCCGGTCGGGACCGT
CTCACTCGCTTTTGTAAAAGAATATAATAAGTTCGTCAACCTGGAACGCCGGTTTGATGACGCGGGTGTTGCGCCTGGTG
CATAA

Upstream 100 bases:

>100_bases
ATATTTCTACAACATGCGATTCTGCAAGAGTCTATTTTTTTTCTGTAAAAATGGTAAAATAGACGTTGGGTTATTTTTAA
ATGGGAGGACGGTGCTTAAC

Downstream 100 bases:

>100_bases
ATCCCTGAGACATGTTCTCAGGGATTTTTCTTTTTTCTTGCATTGCGGTTTTTACCGATTTCAAATAAACCCGTCGCTGT
TAATCCGGCCAGTCCTCCTG

Product: replicative DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 453

Protein sequence:

>454_residues
MTDLLNDRLPPQNIEAEQAVLGAVFLEPSALTLASEVLIPDDFYRMSHQKIFNAMLVLGDRGEPVDLVTVTSELANTDLL
EEVGGISYLTDIANSVPTAANIEYYAKIVEEKSILRRLIRTATTIAQDGYTREDEVEDLLSEAEKTIMEVAQRKNSGAFQ
NIKDVLVQTYDNIEQLHNRKGDITGIPTGFTELDRMTAGFQRNDLIIVAARPSVGKTAFALNIAQNVATKTDESVAIFSL
EMGAEQLVMRMLCAEGNINAQNLRTGNLTEEDWGKLTMAMGSLSNSGIFIDDTPGIRVSEIRSKCRRLKQENGLGMILID
YLQLIQGSGRSSDNRQQEVSEISRALKALARELEVPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDADIVAFLYRDD
YYDKESENKNIIEIIIAKQRNGPVGTVSLAFVKEYNKFVNLERRFDDAGVAPGA

Sequences:

>Translated_454_residues
MTDLLNDRLPPQNIEAEQAVLGAVFLEPSALTLASEVLIPDDFYRMSHQKIFNAMLVLGDRGEPVDLVTVTSELANTDLL
EEVGGISYLTDIANSVPTAANIEYYAKIVEEKSILRRLIRTATTIAQDGYTREDEVEDLLSEAEKTIMEVAQRKNSGAFQ
NIKDVLVQTYDNIEQLHNRKGDITGIPTGFTELDRMTAGFQRNDLIIVAARPSVGKTAFALNIAQNVATKTDESVAIFSL
EMGAEQLVMRMLCAEGNINAQNLRTGNLTEEDWGKLTMAMGSLSNSGIFIDDTPGIRVSEIRSKCRRLKQENGLGMILID
YLQLIQGSGRSSDNRQQEVSEISRALKALARELEVPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDADIVAFLYRDD
YYDKESENKNIIEIIIAKQRNGPVGTVSLAFVKEYNKFVNLERRFDDAGVAPGA
>Mature_453_residues
TDLLNDRLPPQNIEAEQAVLGAVFLEPSALTLASEVLIPDDFYRMSHQKIFNAMLVLGDRGEPVDLVTVTSELANTDLLE
EVGGISYLTDIANSVPTAANIEYYAKIVEEKSILRRLIRTATTIAQDGYTREDEVEDLLSEAEKTIMEVAQRKNSGAFQN
IKDVLVQTYDNIEQLHNRKGDITGIPTGFTELDRMTAGFQRNDLIIVAARPSVGKTAFALNIAQNVATKTDESVAIFSLE
MGAEQLVMRMLCAEGNINAQNLRTGNLTEEDWGKLTMAMGSLSNSGIFIDDTPGIRVSEIRSKCRRLKQENGLGMILIDY
LQLIQGSGRSSDNRQQEVSEISRALKALARELEVPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDADIVAFLYRDDY
YDKESENKNIIEIIIAKQRNGPVGTVSLAFVKEYNKFVNLERRFDDAGVAPGA

Specific function: Participates In Initiation And Elongation During Chromosome Replication; It Exhibits DNA-Dependent ATPase Activity And Contains Distinct Active Sites For ATP Binding, DNA Binding, And Interaction With DNAc Protein, Primase, And Other Prepriming Proteins.

COG id: COG0305

COG function: function code L; Replicative DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SF4 helicase domain [H]

Homologues:

Organism=Escherichia coli, GI1790486, Length=440, Percent_Identity=47.5, Blast_Score=402, Evalue=1e-113,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007692
- InterPro:   IPR007694
- InterPro:   IPR007693
- InterPro:   IPR016136 [H]

Pfam domain/function: PF00772 DnaB; PF03796 DnaB_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 50377; Mature: 50246

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLLNDRLPPQNIEAEQAVLGAVFLEPSALTLASEVLIPDDFYRMSHQKIFNAMLVLGD
CCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHEECC
RGEPVDLVTVTSELANTDLLEEVGGISYLTDIANSVPTAANIEYYAKIVEEKSILRRLIR
CCCCEEEEEECHHHHCHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
TATTIAQDGYTREDEVEDLLSEAEKTIMEVAQRKNSGAFQNIKDVLVQTYDNIEQLHNRK
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCC
GDITGIPTGFTELDRMTAGFQRNDLIIVAARPSVGKTAFALNIAQNVATKTDESVAIFSL
CCCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEEE
EMGAEQLVMRMLCAEGNINAQNLRTGNLTEEDWGKLTMAMGSLSNSGIFIDDTPGIRVSE
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCHHH
IRSKCRRLKQENGLGMILIDYLQLIQGSGRSSDNRQQEVSEISRALKALARELEVPVIAL
HHHHHHHHHHHCCCEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHH
SQLSRGVEQRQDKRPMMSDIRESGSIEQDADIVAFLYRDDYYDKESENKNIIEIIIAKQR
HHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCEEEEEEEECC
NGPVGTVSLAFVKEYNKFVNLERRFDDAGVAPGA
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TDLLNDRLPPQNIEAEQAVLGAVFLEPSALTLASEVLIPDDFYRMSHQKIFNAMLVLGD
CCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHEECC
RGEPVDLVTVTSELANTDLLEEVGGISYLTDIANSVPTAANIEYYAKIVEEKSILRRLIR
CCCCEEEEEECHHHHCHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
TATTIAQDGYTREDEVEDLLSEAEKTIMEVAQRKNSGAFQNIKDVLVQTYDNIEQLHNRK
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCC
GDITGIPTGFTELDRMTAGFQRNDLIIVAARPSVGKTAFALNIAQNVATKTDESVAIFSL
CCCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEEE
EMGAEQLVMRMLCAEGNINAQNLRTGNLTEEDWGKLTMAMGSLSNSGIFIDDTPGIRVSE
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCHHH
IRSKCRRLKQENGLGMILIDYLQLIQGSGRSSDNRQQEVSEISRALKALARELEVPVIAL
HHHHHHHHHHHCCCEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHH
SQLSRGVEQRQDKRPMMSDIRESGSIEQDADIVAFLYRDDYYDKESENKNIIEIIIAKQR
HHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCEEEEEEEECC
NGPVGTVSLAFVKEYNKFVNLERRFDDAGVAPGA
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 1312531 [H]