Click here to switch to the map view.

The map label for this gene is ydgK [H]

Identifier: 52787780

GI number: 52787780

Start: 3927405

End: 3928634

Strand: Reverse

Name: ydgK [H]

Synonym: BLi04103

Alternate gene names: 52787780

Gene position: 3928634-3927405 (Counterclockwise)

Preceding gene: 52787781

Following gene: 52787777

Centisome position: 93.04

GC content: 50.73

Gene sequence:

>1230_bases
ATGGGTACGCTTAACAGCCAGGCAGATCTTGCGGCTCATTCGAAAGCAAAGCCGAACAGGGTATGGATCGCTGTCATATT
GGGTATTTTATCGGGAATCGGTCCGGTTGTGATCGATTTATATTTGCCCGGCCTTCCACAGATGGCAACTGATTTACATA
CGAATGCTTCCGTCGTTCAGCTCAGTTTAACATCGTGTTTACTGGGGCTGGCAATCGGCCAAATTGTCATCGGCCCTTTC
AGCGATGTCCTTGGAAGAAGGCTTCCGCTGATCGTGTCGCTGTCCGTTTTTGCCGCGGCCTCTTTTTTATGTGCTATGAC
ATCTTCTGTATGGGTTTTGATCGCGATGCGCTTTATTCAAGGCGCGGCGGGGGCAGGCGGCATCGTCATATCACGCGCGA
TTGCCCGTGATCTATATTCTGGAACAGAATTGACAAAGTTCTTTTCGCTCTTGATGCTTGTTAACGGGATAGCGCCTATC
ATATCTCCGGTAGCGGGCGGACAGCTGATGAAATGGACGACGTGGAACGGCGTATTTTTCATCATCGGCCTTTTTGGCCT
GCTGATGATTTTGTCCGTTATATTCGGGGTTAAAGAGTCGCTGTCTCCGGAAAACCGTACGGCAGGCGGATTCAAAGAGA
CGTTTGTATCATTTGGAAGGCTCTTCGGCCAGCGTACATTTATGGGATACGCCTTGGCGCAAGGGCTGATCGTAGCGGGG
ATGTTCGGCTATATATCGGCCTCTCCGTTTGTTTTGCAGGACATTTACAAATTGTCGGCTCAAGCCTTTAGTTTTTGTTT
CGCATTAAACGGCCTGGGCATTATTATCGCAGCTCAGATTACGGGCAGGCTTGCCGGCCGGTTCGGTGAAGCGTCCCTTT
TGCGGAGCGGTTTGCTGCTGTCTTTTACCGCAAGCGTTGTTTTATTTGTTTCTGTCTTTTTTAAAGCTCCGCTGATTCTT
ATTTTAATCCCGCTGTTTGTCGTGGTTTCCTGCATCGGAATCGTGACGACGACCAGCGGATCCTTGGCCATGCAGAGCCA
GGGGAAATCAGCCGGGAGCGCATCTGCGCTTCTAGGACTGCTTCCGTTTATTTTAGGAGCTGCCGCGGCGCCGCTCGTCG
GTATTGCCGGAAGCCATACAGCTTTGCCGATGGCAGTCGTCATTCTGTTTTGCAATATCAGCGCGCTCGCTTGTTTTAAC
ATACTGGTTCGGCGGGCAGCGCTTAAATGA

Upstream 100 bases:

>100_bases
CTCGCCCGGTTTTTCTAATTGTCATCTTCATAACTTAAGGTATACAATACACTGGAAGGTTTCGAGGGCGTATTTAAAAA
TATAATAAAGGAGTGATCCA

Downstream 100 bases:

>100_bases
AAAAAAGCCTGGCGGCTCTTATGCCGGCAGGCTTAAAATTTTACCGTGGCAGGATATCAACTGTAGCTTCTGCGTGGTTG
TAGTTTCGCCCGAACTTTTG

Product: hypothetical protein

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 408

Protein sequence:

>409_residues
MGTLNSQADLAAHSKAKPNRVWIAVILGILSGIGPVVIDLYLPGLPQMATDLHTNASVVQLSLTSCLLGLAIGQIVIGPF
SDVLGRRLPLIVSLSVFAAASFLCAMTSSVWVLIAMRFIQGAAGAGGIVISRAIARDLYSGTELTKFFSLLMLVNGIAPI
ISPVAGGQLMKWTTWNGVFFIIGLFGLLMILSVIFGVKESLSPENRTAGGFKETFVSFGRLFGQRTFMGYALAQGLIVAG
MFGYISASPFVLQDIYKLSAQAFSFCFALNGLGIIIAAQITGRLAGRFGEASLLRSGLLLSFTASVVLFVSVFFKAPLIL
ILIPLFVVVSCIGIVTTTSGSLAMQSQGKSAGSASALLGLLPFILGAAAAPLVGIAGSHTALPMAVVILFCNISALACFN
ILVRRAALK

Sequences:

>Translated_409_residues
MGTLNSQADLAAHSKAKPNRVWIAVILGILSGIGPVVIDLYLPGLPQMATDLHTNASVVQLSLTSCLLGLAIGQIVIGPF
SDVLGRRLPLIVSLSVFAAASFLCAMTSSVWVLIAMRFIQGAAGAGGIVISRAIARDLYSGTELTKFFSLLMLVNGIAPI
ISPVAGGQLMKWTTWNGVFFIIGLFGLLMILSVIFGVKESLSPENRTAGGFKETFVSFGRLFGQRTFMGYALAQGLIVAG
MFGYISASPFVLQDIYKLSAQAFSFCFALNGLGIIIAAQITGRLAGRFGEASLLRSGLLLSFTASVVLFVSVFFKAPLIL
ILIPLFVVVSCIGIVTTTSGSLAMQSQGKSAGSASALLGLLPFILGAAAAPLVGIAGSHTALPMAVVILFCNISALACFN
ILVRRAALK
>Mature_408_residues
GTLNSQADLAAHSKAKPNRVWIAVILGILSGIGPVVIDLYLPGLPQMATDLHTNASVVQLSLTSCLLGLAIGQIVIGPFS
DVLGRRLPLIVSLSVFAAASFLCAMTSSVWVLIAMRFIQGAAGAGGIVISRAIARDLYSGTELTKFFSLLMLVNGIAPII
SPVAGGQLMKWTTWNGVFFIIGLFGLLMILSVIFGVKESLSPENRTAGGFKETFVSFGRLFGQRTFMGYALAQGLIVAGM
FGYISASPFVLQDIYKLSAQAFSFCFALNGLGIIIAAQITGRLAGRFGEASLLRSGLLLSFTASVVLFVSVFFKAPLILI
LIPLFVVVSCIGIVTTTSGSLAMQSQGKSAGSASALLGLLPFILGAAAAPLVGIAGSHTALPMAVVILFCNISALACFNI
LVRRAALK

Specific function: Involved In Sulfonamide (Sulfathiazole) And Bicyclomycin Resistance. Probable Membrane Translocase. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Bcr/CmlA family [H]

Homologues:

Organism=Escherichia coli, GI1788509, Length=374, Percent_Identity=32.8877005347594, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI48994889, Length=345, Percent_Identity=27.536231884058, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI87082312, Length=328, Percent_Identity=28.3536585365854, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790146, Length=278, Percent_Identity=25.5395683453237, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1790794, Length=247, Percent_Identity=25.9109311740891, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790195, Length=170, Percent_Identity=29.4117647058824, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004812
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 42701; Mature: 42569

Theoretical pI: Translated: 10.37; Mature: 10.37

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GTLNSQADLAAHSKAKPNRVWIAVILGILSGIGPVVIDLYLPGLPQMATDLHTNASVVQ
CCCCCCHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHCCCCHHHH
LSLTSCLLGLAIGQIVIGPFSDVLGRRLPLIVSLSVFAAASFLCAMTSSVWVLIAMRFIQ
HHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAAGAGGIVISRAIARDLYSGTELTKFFSLLMLVNGIAPIISPVAGGQLMKWTTWNGVFF
CCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHH
IIGLFGLLMILSVIFGVKESLSPENRTAGGFKETFVSFGRLFGQRTFMGYALAQGLIVAG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MFGYISASPFVLQDIYKLSAQAFSFCFALNGLGIIIAAQITGRLAGRFGEASLLRSGLLL
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHCCCHHHHHHHHHHH
SFTASVVLFVSVFFKAPLILILIPLFVVVSCIGIVTTTSGSLAMQSQGKSAGSASALLGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHH
LPFILGAAAAPLVGIAGSHTALPMAVVILFCNISALACFNILVRRAALK
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9202461 [H]