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The map label for this gene is licC [H]

Identifier: 52787765

GI number: 52787765

Start: 3912431

End: 3913783

Strand: Reverse

Name: licC [H]

Synonym: BLi04088

Alternate gene names: 52787765

Gene position: 3913783-3912431 (Counterclockwise)

Preceding gene: 52787766

Following gene: 52787764

Centisome position: 92.69

GC content: 51.66

Gene sequence:

>1353_bases
GTGAACAAGTTTAATGCATTTTTAGAGGAGAAGATCATGCCGGTTGCCGGCAGAATTGCCGCCCAGCGCCATTTGCAGGC
TCTCAGAGACGGCATTATTCTGACCATGCCATTAATCATTATCGGATCGCTGTTTCTCATTTTAGCCAATTTGCCGATTC
CGGGATATCCGGAATTCATGGCGGGGATTTTCGGCGATCAATGGGCTGAGAAATTAAGCTATCCGGTTAATGTCAGCTTT
GACATTATGGCGCTGATCGCCACGTTTGGCATCGCCTACCGTCTGGCGGAGAAATATGATATCGATGCCCTGTCATCGGG
CGCCATTGCCGTAGCAGCTTTTCTGCTTGCGACCCCCTACCAGATTCCGTTCACACCCGAAGGCGCAACAGAGGAAATTT
TAGTGTCAGGCGGCATCCCGATTTCATTAATGGGAAGCAAAGGTCTGTTTGTCGGCATGCTGATCGCGATGTTCTCCACT
GAGGTTTACCGCTGGGTCGTTCAAAAGGATATTGTCGTCAAAATGCCGGACGGCGTACCGCCGGCTGTCAGCAAATCATT
TATCGCTCTGATTCCGGGATTCGCCGTTATCGGCTCGATCTGGGCGGCCCGCCTTTTAATTGAAATGACGCCGTTTGAAA
GCCTCCATAATGTCGTCAACGTCCTTTTGGGAACGCCTCTTTCCGTCCTTGGCGGCAGTCTCGGCGGAAGCCTTATTGCC
GAAACTGTGAAAATGCTGCTGTGGTCCTGCGGCCTTCATGGAGCAAACATTGTCGGCGGAGTGATGTCGCCGATCTGGTA
CGGAGCGATGGACGAAAACCGTCTCGCTTTCCAAGCCGGAGAAGCGCTCCCGAACATATTTACGACGCAGTTTTTTGAGA
TTTGGATCAACATCGGCGGCAGCGGCGCTACTTTGGCTTTGGTCATTACGATGTTTCTTAGGGCGCGAAGCAAGCAAATG
AAACAGCTCGGCAGACTCGCCATCGGCCCCGCTGTTTTTAACATCAACGAACCGATTATCTTCGGCATGCCGATCGTCAT
GAACCCGATGCTGCTGATCCCGTTCATCGTGTCGCCGCTGCTGATGATAACGGCAACCTATATTGGAATGAGCACAGGTC
TTGTTGCAAAGCCGGCTGGGATTGCCGTGCCGTGGACGATGCCGCCCGGCTTTTCCGGATATTTGGCAACAGGAGGGAAA
ATTTCCGGAGCGGTCATGCAGCTGATCAATCTGTTGATCTCGTTTGTCGTATACTATCCGTTCTTTAGAATGTGGGATAA
ACAAAAGCTGAAAGAAGAGAGCGAACTGGAGACCGGAACGGCTGCAAGCGATGGTCAACAGGTCAGTGTATAG

Upstream 100 bases:

>100_bases
CCGTCGATGTCATCAATACGGTCCATTACGGAACTTGTAATGGAGCTGAAGTGTTAAAATCCGCCGAACAGCTTGCCGGC
TCTTAAAGGAGGCGGCACAA

Downstream 100 bases:

>100_bases
AAAAGGGGTGCCAAAATGTCCGAGGAATTGGAACAAACGATATTTCAAATTATCCTTCACGGAGGAAACGGCAGGAGCTT
TTGCATGGAAGCGATAGCCG

Product: LicC

Products: protein histidine; sugar phosphate

Alternate protein names: EIIC-Lic; PTS system lichenan-specific EIIC component [H]

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MNKFNAFLEEKIMPVAGRIAAQRHLQALRDGIILTMPLIIIGSLFLILANLPIPGYPEFMAGIFGDQWAEKLSYPVNVSF
DIMALIATFGIAYRLAEKYDIDALSSGAIAVAAFLLATPYQIPFTPEGATEEILVSGGIPISLMGSKGLFVGMLIAMFST
EVYRWVVQKDIVVKMPDGVPPAVSKSFIALIPGFAVIGSIWAARLLIEMTPFESLHNVVNVLLGTPLSVLGGSLGGSLIA
ETVKMLLWSCGLHGANIVGGVMSPIWYGAMDENRLAFQAGEALPNIFTTQFFEIWINIGGSGATLALVITMFLRARSKQM
KQLGRLAIGPAVFNINEPIIFGMPIVMNPMLLIPFIVSPLLMITATYIGMSTGLVAKPAGIAVPWTMPPGFSGYLATGGK
ISGAVMQLINLLISFVVYYPFFRMWDKQKLKEESELETGTAASDGQQVSV

Sequences:

>Translated_450_residues
MNKFNAFLEEKIMPVAGRIAAQRHLQALRDGIILTMPLIIIGSLFLILANLPIPGYPEFMAGIFGDQWAEKLSYPVNVSF
DIMALIATFGIAYRLAEKYDIDALSSGAIAVAAFLLATPYQIPFTPEGATEEILVSGGIPISLMGSKGLFVGMLIAMFST
EVYRWVVQKDIVVKMPDGVPPAVSKSFIALIPGFAVIGSIWAARLLIEMTPFESLHNVVNVLLGTPLSVLGGSLGGSLIA
ETVKMLLWSCGLHGANIVGGVMSPIWYGAMDENRLAFQAGEALPNIFTTQFFEIWINIGGSGATLALVITMFLRARSKQM
KQLGRLAIGPAVFNINEPIIFGMPIVMNPMLLIPFIVSPLLMITATYIGMSTGLVAKPAGIAVPWTMPPGFSGYLATGGK
ISGAVMQLINLLISFVVYYPFFRMWDKQKLKEESELETGTAASDGQQVSV
>Mature_450_residues
MNKFNAFLEEKIMPVAGRIAAQRHLQALRDGIILTMPLIIIGSLFLILANLPIPGYPEFMAGIFGDQWAEKLSYPVNVSF
DIMALIATFGIAYRLAEKYDIDALSSGAIAVAAFLLATPYQIPFTPEGATEEILVSGGIPISLMGSKGLFVGMLIAMFST
EVYRWVVQKDIVVKMPDGVPPAVSKSFIALIPGFAVIGSIWAARLLIEMTPFESLHNVVNVLLGTPLSVLGGSLGGSLIA
ETVKMLLWSCGLHGANIVGGVMSPIWYGAMDENRLAFQAGEALPNIFTTQFFEIWINIGGSGATLALVITMFLRARSKQM
KQLGRLAIGPAVFNINEPIIFGMPIVMNPMLLIPFIVSPLLMITATYIGMSTGLVAKPAGIAVPWTMPPGFSGYLATGGK
ISGAVMQLINLLISFVVYYPFFRMWDKQKLKEESELETGTAASDGQQVSV

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG1455

COG function: function code G; Phosphotransferase system cellobiose-specific component IIC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788032, Length=475, Percent_Identity=32, Blast_Score=213, Evalue=3e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003352
- InterPro:   IPR004796
- InterPro:   IPR004501 [H]

Pfam domain/function: PF02378 PTS_EIIC [H]

EC number: 2.7.1.69

Molecular weight: Translated: 48490; Mature: 48490

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS51105 PTS_EIIC_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKFNAFLEEKIMPVAGRIAAQRHLQALRDGIILTMPLIIIGSLFLILANLPIPGYPEFM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
AGIFGDQWAEKLSYPVNVSFDIMALIATFGIAYRLAEKYDIDALSSGAIAVAAFLLATPY
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCC
QIPFTPEGATEEILVSGGIPISLMGSKGLFVGMLIAMFSTEVYRWVVQKDIVVKMPDGVP
CCCCCCCCCCCCEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCC
PAVSKSFIALIPGFAVIGSIWAARLLIEMTPFESLHNVVNVLLGTPLSVLGGSLGGSLIA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHCCCCCHHHHH
ETVKMLLWSCGLHGANIVGGVMSPIWYGAMDENRLAFQAGEALPNIFTTQFFEIWINIGG
HHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHCHHCHHHHHHHHHHHHEECCC
SGATLALVITMFLRARSKQMKQLGRLAIGPAVFNINEPIIFGMPIVMNPMLLIPFIVSPL
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEECCHHHHHHHHHHHHHHHHH
LMITATYIGMSTGLVAKPAGIAVPWTMPPGFSGYLATGGKISGAVMQLINLLISFVVYYP
HHHHHHHHHHCCCCEECCCCEEECCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHH
FFRMWDKQKLKEESELETGTAASDGQQVSV
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNKFNAFLEEKIMPVAGRIAAQRHLQALRDGIILTMPLIIIGSLFLILANLPIPGYPEFM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
AGIFGDQWAEKLSYPVNVSFDIMALIATFGIAYRLAEKYDIDALSSGAIAVAAFLLATPY
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCC
QIPFTPEGATEEILVSGGIPISLMGSKGLFVGMLIAMFSTEVYRWVVQKDIVVKMPDGVP
CCCCCCCCCCCCEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCC
PAVSKSFIALIPGFAVIGSIWAARLLIEMTPFESLHNVVNVLLGTPLSVLGGSLGGSLIA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHCCCCCHHHHH
ETVKMLLWSCGLHGANIVGGVMSPIWYGAMDENRLAFQAGEALPNIFTTQFFEIWINIGG
HHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHCHHCHHHHHHHHHHHHEECCC
SGATLALVITMFLRARSKQMKQLGRLAIGPAVFNINEPIIFGMPIVMNPMLLIPFIVSPL
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEECCHHHHHHHHHHHHHHHHH
LMITATYIGMSTGLVAKPAGIAVPWTMPPGFSGYLATGGKISGAVMQLINLLISFVVYYP
HHHHHHHHHHCCCCEECCCCEEECCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHH
FFRMWDKQKLKEESELETGTAASDGQQVSV
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N(pi)-phosphohistidine; sugar

Specific reaction: protein N(pi)-phosphohistidine + sugar = protein histidine + sugar phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8990303; 8969509; 9384377 [H]