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The map label for this gene is licA [H]

Identifier: 52787764

GI number: 52787764

Start: 3912086

End: 3912415

Strand: Reverse

Name: licA [H]

Synonym: BLi04087

Alternate gene names: 52787764

Gene position: 3912415-3912086 (Counterclockwise)

Preceding gene: 52787765

Following gene: 52787763

Centisome position: 92.65

GC content: 45.76

Gene sequence:

>330_bases
ATGTCCGAGGAATTGGAACAAACGATATTTCAAATTATCCTTCACGGAGGAAACGGCAGGAGCTTTTGCATGGAAGCGAT
AGCCGAAGCCAAAAAGGGAGATTTCGCAGCTGCAAAAGAAAAGATCCGGGCGGCTGACGAAGAACTGATCAGGGCGCATC
ACTTTCAGACAGCTTTGATTCAAAATGAAGCGAAGGGTGCGAAAACCGAACCTTCACTGCTCATGATTCATGCCCAGGAT
CATTTAATGAATGCGATGACCATGAAAGATTTGGCCGCGGAGATTGTCGAGCTCTATGAAAAAATGAATATCCACGGAGG
TGTCAATTGA

Upstream 100 bases:

>100_bases
AATGTGGGATAAACAAAAGCTGAAAGAAGAGAGCGAACTGGAGACCGGAACGGCTGCAAGCGATGGTCAACAGGTCAGTG
TATAGAAAAGGGGTGCCAAA

Downstream 100 bases:

>100_bases
TGAAAAAAGGATTGAAAATCGTAACAATTGGCGGAGGTTCAAGTTATACGCCCGAGCTTGTCGAGGGATTAATCAAACGG
CATGACGAGCTTCCGGTCAG

Product: LicA

Products: protein histidine; sugar phosphate

Alternate protein names: EIIA-Lic; EIII-Lic; PTS system lichenan-specific EIIA component [H]

Number of amino acids: Translated: 109; Mature: 108

Protein sequence:

>109_residues
MSEELEQTIFQIILHGGNGRSFCMEAIAEAKKGDFAAAKEKIRAADEELIRAHHFQTALIQNEAKGAKTEPSLLMIHAQD
HLMNAMTMKDLAAEIVELYEKMNIHGGVN

Sequences:

>Translated_109_residues
MSEELEQTIFQIILHGGNGRSFCMEAIAEAKKGDFAAAKEKIRAADEELIRAHHFQTALIQNEAKGAKTEPSLLMIHAQD
HLMNAMTMKDLAAEIVELYEKMNIHGGVN
>Mature_108_residues
SEELEQTIFQIILHGGNGRSFCMEAIAEAKKGDFAAAKEKIRAADEELIRAHHFQTALIQNEAKGAKTEPSLLMIHAQDH
LMNAMTMKDLAAEIVELYEKMNIHGGVN

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG1447

COG function: function code G; Phosphotransferase system cellobiose-specific component IIA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIA type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788031, Length=101, Percent_Identity=42.5742574257426, Blast_Score=86, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003188 [H]

Pfam domain/function: PF02255 PTS_IIA [H]

EC number: 2.7.1.69

Molecular weight: Translated: 12106; Mature: 11975

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: PS51095 PTS_EIIA_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
6.4 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEELEQTIFQIILHGGNGRSFCMEAIAEAKKGDFAAAKEKIRAADEELIRAHHFQTALI
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QNEAKGAKTEPSLLMIHAQDHLMNAMTMKDLAAEIVELYEKMNIHGGVN
HHHCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SEELEQTIFQIILHGGNGRSFCMEAIAEAKKGDFAAAKEKIRAADEELIRAHHFQTALI
CHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QNEAKGAKTEPSLLMIHAQDHLMNAMTMKDLAAEIVELYEKMNIHGGVN
HHHCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N(pi)-phosphohistidine; sugar

Specific reaction: protein N(pi)-phosphohistidine + sugar = protein histidine + sugar phosphate

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8990303; 8969509; 9384377 [H]