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The map label for this gene is uvrB [H]

Identifier: 52787440

GI number: 52787440

Start: 3580577

End: 3582562

Strand: Reverse

Name: uvrB [H]

Synonym: BLi03759

Alternate gene names: 52787440

Gene position: 3582562-3580577 (Counterclockwise)

Preceding gene: 52787441

Following gene: 52787439

Centisome position: 84.84

GC content: 49.95

Gene sequence:

>1986_bases
GTGAAAGACCGCTTTGAATTAGTCTCGAATTATCAGCCCCAGGGGGATCAGCCGAAAGCGATTGATCAGCTTGTCAAAGG
AATCAATGAAGGCAGAAAGCATCAGACGCTTTTGGGGGCAACCGGTACTGGAAAGACGTTTACGATGTCGAACGTGATTA
AAGAGGTCAACAAACCGACTCTCGTCATCGCCCACAACAAAACGTTAGCCGGGCAGCTTTACAGCGAGTTTAAAGAATTT
TTCCCCAACAACGCAGTCGAATATTTTGTCAGCTATTATGACTATTACCAGCCTGAGGCCTACGTGCCCCAGACTGATAC
ATTTATCGAAAAAGATGCCAGCATTAACGATGAGATTGATAAATTAAGGCACTCTGCCACGTCTGCTCTTTTTGAACGCA
AAGATGTCATCATTGTGGCGAGTGTCTCTTGTATTTACGGCTTGGGTTCTCCTGAGGAATACAGGGAAATGGTGCTCTCG
CTCAGAACGGAAATGGAAATCGAGCGGAATGAGCTGCTCAGAAAGCTCGTTGACATCCAATATGCGCGGAATGACATCGA
TTTTCAGCGCGGAACATTCAGGGTGCGCGGCGATGTCGTCGAGATCTTTCCGGCTTCAAGGGATGAGCACTGCGTCCGAG
TTGAATTTTTCGGGGACGAAATCGAACGGATCAGGGAAGTGGATGCCCTGACTGGCGAAATTTTAGGGGAGAGGGAACAC
GTCGCGATCTTCCCGGCTTCCCACTTCGTCACCCGGGAAGAAAAGATGAAGAAAGCGATCATAAACATTGAAGAGGAGCT
GGAAGAGCGCCTCAAAGCGCTTCGTGAAGAAGGCAAGCTCCTTGAAGCGCAGCGTCTGGAACAGCGGACGAGATACGATT
TGGAAATGATGCGCGAAATGGGCTTTTGCTCGGGCATCGAAAACTATTCAAGACATTTGACGCTTCGTCCGGCAGGTTCG
ACTCCATATACGCTGCTCGATTACTTTCCGGATGATTTCCTGATGGTCATAGATGAGTCGCATGTCACCATACCGCAGAT
CAGAGGAATGTACAACGGAGACCAGGCGAGAAAACAGGTTCTCGTCGATCATGGATTCAGGCTGCCTTCCGCTTTGGATA
ACCGTCCGCTCAGGTTTGAAGAGTTTGAAAAGCACATTCACAACATCGTGTATGTGTCGGCTACGCCGGGGCCTTATGAA
CTTGAGCATACGCCTGAAATGGTAGAGCAGATCATCCGGCCGACAGGGCTGCTCGATCCGATTATTGAGGTAAGGCCGAT
TGAAGGGCAGATCGATGATCTGATCGGTGAAATCCAGCAGAGAATCGAGCGGAATGAACGCGTCCTCGTCACGACGCTGA
CGAAAAAAATGTCCGAGGATTTGACGGATTATCTGAAGGAAATCGGTATCAAGGTCACGTACCTGCATTCAGAGATTAAA
ACGCTGGAGCGGATCGAGATCATACGCGACCTTCGCCTCGGCAAGCATGACGTTCTCGTCGGCATCAACCTGCTGAGGGA
AGGACTCGATATTCCTGAGGTTTCACTCGTCGCCATTCTTGACGCAGACAAAGAAGGCTTTTTGCGGTCCGAACGCTCGC
TCATCCAAACGATCGGCCGCGCCGCCAGAAATGCCGAAGGCCGCGTAATCATGTATGCCGACAAAATCACCAACTCGATG
GAAATCGCAATCAATGAAACGAAGCGCCGCCGCGAACAGCAGGAGGCTTATAATGAGAAACACGGCATTACGCCGAAAAC
GATCAACAAAAAGATCAGGGACGTCATCCGGGCAACTCATGCTGCTGAAGACCAGGAAGAATATCAAGTGAAAGAGGAGC
CGAAGCTTTCGAAGATGACGAAGAAAGAGCGGGAAAAAGTGATCGCTCAAATGGAAAGCGACATGAAGGAAGCGGCAAAA
GCGCTTGACTTTGAACGCGCCGCCGAGCTTCGCGACTTGCTCCTAGAGTTAAAATCGGAAGGATGA

Upstream 100 bases:

>100_bases
TTGTGGGAAAACACAAAAACCGAACTTTAGTTCGTATTTTTGCTTCGGGTGTGTTAAAATAATAAACAGGAAGATTTCGT
AAAGAAACGGAGGCTTTTAT

Downstream 100 bases:

>100_bases
ATAGAAAATGGCAACGAAACGAATTGAGGTGAAAGGTGCAAGGGCCCATAACCTGAAAAATATCGATGTCTCTATTCCGA
GGGATCAGCTTGTCGTTTTG

Product: excinuclease ABC subunit B

Products: NA

Alternate protein names: Protein uvrB; Excinuclease ABC subunit B [H]

Number of amino acids: Translated: 661; Mature: 661

Protein sequence:

>661_residues
MKDRFELVSNYQPQGDQPKAIDQLVKGINEGRKHQTLLGATGTGKTFTMSNVIKEVNKPTLVIAHNKTLAGQLYSEFKEF
FPNNAVEYFVSYYDYYQPEAYVPQTDTFIEKDASINDEIDKLRHSATSALFERKDVIIVASVSCIYGLGSPEEYREMVLS
LRTEMEIERNELLRKLVDIQYARNDIDFQRGTFRVRGDVVEIFPASRDEHCVRVEFFGDEIERIREVDALTGEILGEREH
VAIFPASHFVTREEKMKKAIINIEEELEERLKALREEGKLLEAQRLEQRTRYDLEMMREMGFCSGIENYSRHLTLRPAGS
TPYTLLDYFPDDFLMVIDESHVTIPQIRGMYNGDQARKQVLVDHGFRLPSALDNRPLRFEEFEKHIHNIVYVSATPGPYE
LEHTPEMVEQIIRPTGLLDPIIEVRPIEGQIDDLIGEIQQRIERNERVLVTTLTKKMSEDLTDYLKEIGIKVTYLHSEIK
TLERIEIIRDLRLGKHDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNAEGRVIMYADKITNSM
EIAINETKRRREQQEAYNEKHGITPKTINKKIRDVIRATHAAEDQEEYQVKEEPKLSKMTKKEREKVIAQMESDMKEAAK
ALDFERAAELRDLLLELKSEG

Sequences:

>Translated_661_residues
MKDRFELVSNYQPQGDQPKAIDQLVKGINEGRKHQTLLGATGTGKTFTMSNVIKEVNKPTLVIAHNKTLAGQLYSEFKEF
FPNNAVEYFVSYYDYYQPEAYVPQTDTFIEKDASINDEIDKLRHSATSALFERKDVIIVASVSCIYGLGSPEEYREMVLS
LRTEMEIERNELLRKLVDIQYARNDIDFQRGTFRVRGDVVEIFPASRDEHCVRVEFFGDEIERIREVDALTGEILGEREH
VAIFPASHFVTREEKMKKAIINIEEELEERLKALREEGKLLEAQRLEQRTRYDLEMMREMGFCSGIENYSRHLTLRPAGS
TPYTLLDYFPDDFLMVIDESHVTIPQIRGMYNGDQARKQVLVDHGFRLPSALDNRPLRFEEFEKHIHNIVYVSATPGPYE
LEHTPEMVEQIIRPTGLLDPIIEVRPIEGQIDDLIGEIQQRIERNERVLVTTLTKKMSEDLTDYLKEIGIKVTYLHSEIK
TLERIEIIRDLRLGKHDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNAEGRVIMYADKITNSM
EIAINETKRRREQQEAYNEKHGITPKTINKKIRDVIRATHAAEDQEEYQVKEEPKLSKMTKKEREKVIAQMESDMKEAAK
ALDFERAAELRDLLLELKSEG
>Mature_661_residues
MKDRFELVSNYQPQGDQPKAIDQLVKGINEGRKHQTLLGATGTGKTFTMSNVIKEVNKPTLVIAHNKTLAGQLYSEFKEF
FPNNAVEYFVSYYDYYQPEAYVPQTDTFIEKDASINDEIDKLRHSATSALFERKDVIIVASVSCIYGLGSPEEYREMVLS
LRTEMEIERNELLRKLVDIQYARNDIDFQRGTFRVRGDVVEIFPASRDEHCVRVEFFGDEIERIREVDALTGEILGEREH
VAIFPASHFVTREEKMKKAIINIEEELEERLKALREEGKLLEAQRLEQRTRYDLEMMREMGFCSGIENYSRHLTLRPAGS
TPYTLLDYFPDDFLMVIDESHVTIPQIRGMYNGDQARKQVLVDHGFRLPSALDNRPLRFEEFEKHIHNIVYVSATPGPYE
LEHTPEMVEQIIRPTGLLDPIIEVRPIEGQIDDLIGEIQQRIERNERVLVTTLTKKMSEDLTDYLKEIGIKVTYLHSEIK
TLERIEIIRDLRLGKHDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNAEGRVIMYADKITNSM
EIAINETKRRREQQEAYNEKHGITPKTINKKIRDVIRATHAAEDQEEYQVKEEPKLSKMTKKEREKVIAQMESDMKEAAK
ALDFERAAELRDLLLELKSEG

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. Upon binding of the uvrA(2)B(2) complex to a putative damaged site, the DNA

COG id: COG0556

COG function: function code L; Helicase subunit of the DNA excision repair complex

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Escherichia coli, GI1786996, Length=666, Percent_Identity=60.2102102102102, Blast_Score=791, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR006935
- InterPro:   IPR001943
- InterPro:   IPR004807
- InterPro:   IPR009055 [H]

Pfam domain/function: PF00271 Helicase_C; PF04851 ResIII; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 76439; Mature: 76439

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS50151 UVR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDRFELVSNYQPQGDQPKAIDQLVKGINEGRKHQTLLGATGTGKTFTMSNVIKEVNKPT
CCCHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCEEEHHHHHHHCCCCE
LVIAHNKTLAGQLYSEFKEFFPNNAVEYFVSYYDYYQPEAYVPQTDTFIEKDASINDEID
EEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCHHHH
KLRHSATSALFERKDVIIVASVSCIYGLGSPEEYREMVLSLRTEMEIERNELLRKLVDIQ
HHHHHHHHHHHHCCCEEEEEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YARNDIDFQRGTFRVRGDVVEIFPASRDEHCVRVEFFGDEIERIREVDALTGEILGEREH
HHCCCCCCCCCEEEEECCEEEECCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCE
VAIFPASHFVTREEKMKKAIINIEEELEERLKALREEGKLLEAQRLEQRTRYDLEMMREM
EEEECCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
GFCSGIENYSRHLTLRPAGSTPYTLLDYFPDDFLMVIDESHVTIPQIRGMYNGDQARKQV
HHHCCHHHHHCEEEEEECCCCCCHHHHHCCCCEEEEEECCCCCHHHHCCCCCCHHHHHHH
LVDHGFRLPSALDNRPLRFEEFEKHIHNIVYVSATPGPYELEHTPEMVEQIIRPTGLLDP
HHHCCCCCCHHCCCCCCCHHHHHHHHHHEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCC
IIEVRPIEGQIDDLIGEIQQRIERNERVLVTTLTKKMSEDLTDYLKEIGIKVTYLHSEIK
CHHEECCCCHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHCCEEEEEHHHHH
TLERIEIIRDLRLGKHDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGR
HHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHH
AARNAEGRVIMYADKITNSMEIAINETKRRREQQEAYNEKHGITPKTINKKIRDVIRATH
HHCCCCCCEEEEECCCCCCCEEEECHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
AAEDQEEYQVKEEPKLSKMTKKEREKVIAQMESDMKEAAKALDFERAAELRDLLLELKSE
CCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCC
G
C
>Mature Secondary Structure
MKDRFELVSNYQPQGDQPKAIDQLVKGINEGRKHQTLLGATGTGKTFTMSNVIKEVNKPT
CCCHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCEEEHHHHHHHCCCCE
LVIAHNKTLAGQLYSEFKEFFPNNAVEYFVSYYDYYQPEAYVPQTDTFIEKDASINDEID
EEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCHHHH
KLRHSATSALFERKDVIIVASVSCIYGLGSPEEYREMVLSLRTEMEIERNELLRKLVDIQ
HHHHHHHHHHHHCCCEEEEEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YARNDIDFQRGTFRVRGDVVEIFPASRDEHCVRVEFFGDEIERIREVDALTGEILGEREH
HHCCCCCCCCCEEEEECCEEEECCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCE
VAIFPASHFVTREEKMKKAIINIEEELEERLKALREEGKLLEAQRLEQRTRYDLEMMREM
EEEECCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
GFCSGIENYSRHLTLRPAGSTPYTLLDYFPDDFLMVIDESHVTIPQIRGMYNGDQARKQV
HHHCCHHHHHCEEEEEECCCCCCHHHHHCCCCEEEEEECCCCCHHHHCCCCCCHHHHHHH
LVDHGFRLPSALDNRPLRFEEFEKHIHNIVYVSATPGPYELEHTPEMVEQIIRPTGLLDP
HHHCCCCCCHHCCCCCCCHHHHHHHHHHEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCC
IIEVRPIEGQIDDLIGEIQQRIERNERVLVTTLTKKMSEDLTDYLKEIGIKVTYLHSEIK
CHHEECCCCHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHCCEEEEEHHHHH
TLERIEIIRDLRLGKHDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGR
HHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHH
AARNAEGRVIMYADKITNSMEIAINETKRRREQQEAYNEKHGITPKTINKKIRDVIRATH
HHCCCCCCEEEEECCCCCCCEEEECHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
AAEDQEEYQVKEEPKLSKMTKKEREKVIAQMESDMKEAAKALDFERAAELRDLLLELKSE
CCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCC
G
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA