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The map label for this gene is accA

Identifier: 52786797

GI number: 52786797

Start: 2955392

End: 2956369

Strand: Reverse

Name: accA

Synonym: BLi03069

Alternate gene names: 52786797

Gene position: 2956369-2955392 (Counterclockwise)

Preceding gene: 52786798

Following gene: 52786796

Centisome position: 70.01

GC content: 47.65

Gene sequence:

>978_bases
GTGGCTGGAGAATTAGAATTTGAAAAACCGGTGGTCGAACTGCGTGAAAAGATCTCCGAATTGAAAAAGTTCACACAGGA
TTCCGATATGGATTTGAGCTCTGAAATTACGAAGCTTGAAGCTCGTCTTGAAAGGCTTGAAGAAGACATTTATACAAATC
TGAAAGCCTGGGACAGAGTCCAGATTGCAAGGCACCCGAACCGTCCGACAACGCTCGATTATATCGAACATCTCTTTACC
GATTTTTTTGAATGCCACGGAGATCGTTATTTCGGTGATGATGAAGCAATTGTCGGCGGAATTGCCAAGTTCCGGGGTCT
TCCTGTGACAGTAATCGGTCAGCAGCGCGGCAAGGATACAAAAGAAAACATCCGCCGCAATTTCGGAATGCCGCATCCTG
AAGGCTACCGCAAAGCGCTCAGGCTGATGAAGCAGGCCGACAAATTTAACAGGCCGATCATCTGCTTTATTGATACAAAA
GGAGCATACCCGGGCAAAGCAGCTGAAGAGCGGGGGCAAAGCGAAGCGATTGCCAAGAATCTTTTTGAAATGGCGGGACT
CTCCGTGCCGGTCATCTCGATCGTCATCGGGGAAGGCGGCAGCGGGGGAGCGCTTGCGCTCGGCGTCGCAAACCGCTTAT
TGATGCTGGAAAACTCAACTTATTCGGTGATCTCTCCCGAGGGAGCTGCTGCTATCCTCTGGAAGGATTCAGGACTCGCG
AAAAAAGCGGCAGAAACAATGAAAATCACCGCTCCGGACCTTAAAGAATTGGATATTATAGATCATGTTATAAAAGAAGT
AAGAGGCGGAGCACACCGCGATGTGGAGCAGCAGGCTGCCTACATCGACGAAGCGCTGAAAGGCGAGCTTAAATCCCTGC
TGAAACTGGATAAGAACGAGCTGATCCAACAAAGATATAACAAGTATAAGTCAATTGGAAAAATTTCGACTGAAAACCAA
TATGTTGGGATAAAATAA

Upstream 100 bases:

>100_bases
TGTTAAAGCATGGCCAGCTTGATTCCGTCGTTCACAGAGCTGACATGAAAAAAACGCTCGGCAGCATTTTGAAAATGCAC
CAAACTGGAGGTGATCTCGA

Downstream 100 bases:

>100_bases
ATAAACGTGAGGCCTTTGGCTCACGTTTATTTTTTATGGGTGAAGGTGAAAAGTGAAAGGATTGTGTCTGCCGCCCGCGA
TTTTTCAAAGAGTTTGCTTA

Product: acetyl-CoA carboxylase carboxyltransferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MAGELEFEKPVVELREKISELKKFTQDSDMDLSSEITKLEARLERLEEDIYTNLKAWDRVQIARHPNRPTTLDYIEHLFT
DFFECHGDRYFGDDEAIVGGIAKFRGLPVTVIGQQRGKDTKENIRRNFGMPHPEGYRKALRLMKQADKFNRPIICFIDTK
GAYPGKAAEERGQSEAIAKNLFEMAGLSVPVISIVIGEGGSGGALALGVANRLLMLENSTYSVISPEGAAAILWKDSGLA
KKAAETMKITAPDLKELDIIDHVIKEVRGGAHRDVEQQAAYIDEALKGELKSLLKLDKNELIQQRYNKYKSIGKISTENQ
YVGIK

Sequences:

>Translated_325_residues
MAGELEFEKPVVELREKISELKKFTQDSDMDLSSEITKLEARLERLEEDIYTNLKAWDRVQIARHPNRPTTLDYIEHLFT
DFFECHGDRYFGDDEAIVGGIAKFRGLPVTVIGQQRGKDTKENIRRNFGMPHPEGYRKALRLMKQADKFNRPIICFIDTK
GAYPGKAAEERGQSEAIAKNLFEMAGLSVPVISIVIGEGGSGGALALGVANRLLMLENSTYSVISPEGAAAILWKDSGLA
KKAAETMKITAPDLKELDIIDHVIKEVRGGAHRDVEQQAAYIDEALKGELKSLLKLDKNELIQQRYNKYKSIGKISTENQ
YVGIK
>Mature_324_residues
AGELEFEKPVVELREKISELKKFTQDSDMDLSSEITKLEARLERLEEDIYTNLKAWDRVQIARHPNRPTTLDYIEHLFTD
FFECHGDRYFGDDEAIVGGIAKFRGLPVTVIGQQRGKDTKENIRRNFGMPHPEGYRKALRLMKQADKFNRPIICFIDTKG
AYPGKAAEERGQSEAIAKNLFEMAGLSVPVISIVIGEGGSGGALALGVANRLLMLENSTYSVISPEGAAAILWKDSGLAK
KAAETMKITAPDLKELDIIDHVIKEVRGGAHRDVEQQAAYIDEALKGELKSLLKLDKNELIQQRYNKYKSIGKISTENQY
VGIK

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family

Homologues:

Organism=Escherichia coli, GI1786382, Length=312, Percent_Identity=54.1666666666667, Blast_Score=334, Evalue=4e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCA_BACLD (Q65G81)

Other databases:

- EMBL:   AE017333
- EMBL:   CP000002
- RefSeq:   YP_080212.1
- RefSeq:   YP_092626.1
- ProteinModelPortal:   Q65G81
- SMR:   Q65G81
- STRING:   Q65G81
- EnsemblBacteria:   EBBACT00000056065
- EnsemblBacteria:   EBBACT00000059361
- GeneID:   3028933
- GeneID:   3098677
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi03069
- KEGG:   bli:BL00404
- NMPDR:   fig|279010.5.peg.3431
- eggNOG:   COG0825
- GeneTree:   EBGT00050000002181
- HOGENOM:   HBG286557
- OMA:   QLTKDIY
- ProtClustDB:   PRK05724
- BioCyc:   BLIC279010-1:BLI03069-MONOMER
- BioCyc:   BLIC279010:BL00404-MONOMER
- HAMAP:   MF_00823
- InterPro:   IPR001095
- InterPro:   IPR011763
- PANTHER:   PTHR22855:SF3
- PRINTS:   PR01069
- TIGRFAMs:   TIGR00513

Pfam domain/function: PF03255 ACCA

EC number: =6.4.1.2

Molecular weight: Translated: 36399; Mature: 36268

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGELEFEKPVVELREKISELKKFTQDSDMDLSSEITKLEARLERLEEDIYTNLKAWDRV
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QIARHPNRPTTLDYIEHLFTDFFECHGDRYFGDDEAIVGGIAKFRGLPVTVIGQQRGKDT
HHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCH
KENIRRNFGMPHPEGYRKALRLMKQADKFNRPIICFIDTKGAYPGKAAEERGQSEAIAKN
HHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHCCHHHHHHHH
LFEMAGLSVPVISIVIGEGGSGGALALGVANRLLMLENSTYSVISPEGAAAILWKDSGLA
HHHHHCCCCCEEEEEEECCCCCCEEHHHHHCEEEEEECCCEEEECCCCCEEEEECCCCCH
KKAAETMKITAPDLKELDIIDHVIKEVRGGAHRDVEQQAAYIDEALKGELKSLLKLDKNE
HHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHH
LIQQRYNKYKSIGKISTENQYVGIK
HHHHHHHHHHHHCCCCCCCCEECCC
>Mature Secondary Structure 
AGELEFEKPVVELREKISELKKFTQDSDMDLSSEITKLEARLERLEEDIYTNLKAWDRV
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QIARHPNRPTTLDYIEHLFTDFFECHGDRYFGDDEAIVGGIAKFRGLPVTVIGQQRGKDT
HHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCH
KENIRRNFGMPHPEGYRKALRLMKQADKFNRPIICFIDTKGAYPGKAAEERGQSEAIAKN
HHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHCCHHHHHHHH
LFEMAGLSVPVISIVIGEGGSGGALALGVANRLLMLENSTYSVISPEGAAAILWKDSGLA
HHHHHCCCCCEEEEEEECCCCCCEEHHHHHCEEEEEECCCEEEECCCCCEEEEECCCCCH
KKAAETMKITAPDLKELDIIDHVIKEVRGGAHRDVEQQAAYIDEALKGELKSLLKLDKNE
HHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHH
LIQQRYNKYKSIGKISTENQYVGIK
HHHHHHHHHHHHCCCCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA