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The map label for this gene is accD

Identifier: 52786798

GI number: 52786798

Start: 2956354

End: 2957229

Strand: Reverse

Name: accD

Synonym: BLi03070

Alternate gene names: 52786798

Gene position: 2957229-2956354 (Counterclockwise)

Preceding gene: 52786799

Following gene: 52786797

Centisome position: 70.03

GC content: 46.8

Gene sequence:

>876_bases
TTGTTAAAAGATATATTCAGCAAAAAGAAAAAAAAATACGCTTCCGTTCCCGCGGAATCAGCGAAGCAAGATGTACCGGA
AGGGATCATGACAAAGTGCCCGGATTGTAAAAAAATCATGCTCACAAAAGAGCTGGATAAAAATTTAAGGGTCTGCATGA
ATTGCGGTTACCATCTTCAAATGAACGCGAAGCAGCGTATAAAAAGCCTGCTGGACGATGGCTCCTTTGAAGAATTCAAT
CAGGATATGATGTCTGAAAACCCGCTGGAGTTCCCGGGATACCTTGAAAAATTGCAAAAAGACCGGGAAAAAACGTCGCT
GAATGAAGCGGTTGTTACCGGGAAAGGGACGATTGACGGATCTCCGGCGGTCGTGGCCGTGATGGATTCATCTTTCAGAA
TGGGAAGCATGGGATCTGTCGTTGGCGAAAAAATTACGCTTGCAATCGAAAAGGCAAGAGAAGAAAAAGTACCTTTCATC
ATTTTTACCGCATCAGGCGGTGCAAGAATGCAGGAAGGCCTTCTCAGCTTGATGCAAATGGCTAAAACAAGCTCCGCTTT
GAAGCTGTTCAGCGAAGAGCAGGGCTTGATCATTTCAGTGATGACGCATCCGACAACAGGCGGCGTATCCGCAAGCTTCG
CATCCCTCGGCGATTACAACCTTGCCGAACCGGGCGCGCTGATAGGCTTTGCCGGAAGAAGAATTATCGAACAAACCATC
CGTGAAGAACTGCCCGAGGATTTTCAGACTGCGGAATTTCTGTTAAAGCATGGCCAGCTTGATTCCGTCGTTCACAGAGC
TGACATGAAAAAAACGCTCGGCAGCATTTTGAAAATGCACCAAACTGGAGGTGATCTCGAGTGGCTGGAGAATTAG

Upstream 100 bases:

>100_bases
TTGACAAAAAAAGTACAATAGTTTCGGTATAGTGATGTTCTAGTCTATAAACAGGACAGGCATACATGAAGAAAACCCTT
CAGAAAAGGGAGGTAATCTT

Downstream 100 bases:

>100_bases
AATTTGAAAAACCGGTGGTCGAACTGCGTGAAAAGATCTCCGAATTGAAAAAGTTCACACAGGATTCCGATATGGATTTG
AGCTCTGAAATTACGAAGCT

Product: acetyl-CoA carboxylase subunit beta

Products: NA

Alternate protein names: ACCase subunit beta; Acetyl-CoA carboxylase carboxyltransferase subunit beta

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MLKDIFSKKKKKYASVPAESAKQDVPEGIMTKCPDCKKIMLTKELDKNLRVCMNCGYHLQMNAKQRIKSLLDDGSFEEFN
QDMMSENPLEFPGYLEKLQKDREKTSLNEAVVTGKGTIDGSPAVVAVMDSSFRMGSMGSVVGEKITLAIEKAREEKVPFI
IFTASGGARMQEGLLSLMQMAKTSSALKLFSEEQGLIISVMTHPTTGGVSASFASLGDYNLAEPGALIGFAGRRIIEQTI
REELPEDFQTAEFLLKHGQLDSVVHRADMKKTLGSILKMHQTGGDLEWLEN

Sequences:

>Translated_291_residues
MLKDIFSKKKKKYASVPAESAKQDVPEGIMTKCPDCKKIMLTKELDKNLRVCMNCGYHLQMNAKQRIKSLLDDGSFEEFN
QDMMSENPLEFPGYLEKLQKDREKTSLNEAVVTGKGTIDGSPAVVAVMDSSFRMGSMGSVVGEKITLAIEKAREEKVPFI
IFTASGGARMQEGLLSLMQMAKTSSALKLFSEEQGLIISVMTHPTTGGVSASFASLGDYNLAEPGALIGFAGRRIIEQTI
REELPEDFQTAEFLLKHGQLDSVVHRADMKKTLGSILKMHQTGGDLEWLEN
>Mature_291_residues
MLKDIFSKKKKKYASVPAESAKQDVPEGIMTKCPDCKKIMLTKELDKNLRVCMNCGYHLQMNAKQRIKSLLDDGSFEEFN
QDMMSENPLEFPGYLEKLQKDREKTSLNEAVVTGKGTIDGSPAVVAVMDSSFRMGSMGSVVGEKITLAIEKAREEKVPFI
IFTASGGARMQEGLLSLMQMAKTSSALKLFSEEQGLIISVMTHPTTGGVSASFASLGDYNLAEPGALIGFAGRRIIEQTI
REELPEDFQTAEFLLKHGQLDSVVHRADMKKTLGSILKMHQTGGDLEWLEN

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccD/PCCB family

Homologues:

Organism=Escherichia coli, GI1788655, Length=259, Percent_Identity=49.8069498069498, Blast_Score=258, Evalue=3e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCD_BACLD (Q65G80)

Other databases:

- EMBL:   CP000002
- EMBL:   AE017333
- RefSeq:   YP_080213.1
- RefSeq:   YP_092627.1
- ProteinModelPortal:   Q65G80
- SMR:   Q65G80
- STRING:   Q65G80
- EnsemblBacteria:   EBBACT00000054204
- EnsemblBacteria:   EBBACT00000058718
- GeneID:   3028929
- GeneID:   3098682
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi03070
- KEGG:   bli:BL00405
- NMPDR:   fig|279010.5.peg.3432
- eggNOG:   COG0777
- GeneTree:   EBGT00050000000002
- HOGENOM:   HBG285696
- OMA:   LEHGMVD
- ProtClustDB:   PRK05654
- BioCyc:   BLIC279010-1:BLI03070-MONOMER
- BioCyc:   BLIC279010:BL00405-MONOMER
- HAMAP:   MF_01395
- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011762
- PRINTS:   PR01070
- TIGRFAMs:   TIGR00515

Pfam domain/function: PF01039 Carboxyl_trans

EC number: =6.4.1.2

Molecular weight: Translated: 32109; Mature: 32109

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKDIFSKKKKKYASVPAESAKQDVPEGIMTKCPDCKKIMLTKELDKNLRVCMNCGYHLQ
CCHHHHHHHHHHHHCCCHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEE
MNAKQRIKSLLDDGSFEEFNQDMMSENPLEFPGYLEKLQKDREKTSLNEAVVTGKGTIDG
ECHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCC
SPAVVAVMDSSFRMGSMGSVVGEKITLAIEKAREEKVPFIIFTASGGARMQEGLLSLMQM
CCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHH
AKTSSALKLFSEEQGLIISVMTHPTTGGVSASFASLGDYNLAEPGALIGFAGRRIIEQTI
HHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
REELPEDFQTAEFLLKHGQLDSVVHRADMKKTLGSILKMHQTGGDLEWLEN
HHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCC
>Mature Secondary Structure
MLKDIFSKKKKKYASVPAESAKQDVPEGIMTKCPDCKKIMLTKELDKNLRVCMNCGYHLQ
CCHHHHHHHHHHHHCCCHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEE
MNAKQRIKSLLDDGSFEEFNQDMMSENPLEFPGYLEKLQKDREKTSLNEAVVTGKGTIDG
ECHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCC
SPAVVAVMDSSFRMGSMGSVVGEKITLAIEKAREEKVPFIIFTASGGARMQEGLLSLMQM
CCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHH
AKTSSALKLFSEEQGLIISVMTHPTTGGVSASFASLGDYNLAEPGALIGFAGRRIIEQTI
HHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
REELPEDFQTAEFLLKHGQLDSVVHRADMKKTLGSILKMHQTGGDLEWLEN
HHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA