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The map label for this gene is nrdR

Identifier: 52786778

GI number: 52786778

Start: 2933543

End: 2934001

Strand: Reverse

Name: nrdR

Synonym: BLi03048

Alternate gene names: 52786778

Gene position: 2934001-2933543 (Counterclockwise)

Preceding gene: 52786779

Following gene: 52786777

Centisome position: 69.48

GC content: 43.79

Gene sequence:

>459_bases
ATGAAATGTCCAGCATGTCAGCATAATGGGACGAGGGTTTTGGACTCCCGTCCGGTTGACGAAGGCAGATCGATTCGCAG
AAGACGCGAATGCGAATCGTGCAACTATCGATTTACTACATTTGAAAAAGTGGAAGAAATTCCGCTCATCGTCGTAAAAA
AAGAAGGAATCCGGGAAGAATTCAGCCGCGAGAAAATGCTCCGCGGTTTGATCAAAGCGTGCGAAAAGCGCCCTGTCGCC
TTGAAGCAGCTTGAGGATATTTGCTTTGAAATTGAAAAAGAGCTTAGAAATCAAGGCGTTTCTGAAGTGAAGAGCGACAT
GATCGGAGAAATGGTGATGGACAGGCTTGCGAAAATCGACGAAGTCGCATATGTCCGATTTGCTTCAGTATACCGCCAAT
TTAAAGATATTAACGTATTTATCGACGAGCTGAAAGATTTAATAAAGAAAGAACGGTAA

Upstream 100 bases:

>100_bases
TTTTGGCTACAGCCGCGGGCTTGTCTCGACGCTATACAGCGAACTGGACGGAAAGCTGCAGGAATCTGTACATTCAAACA
ATTGAATAGGAGCTGAAAAA

Downstream 100 bases:

>100_bases
AGAGCTGTAAATTGATCCAGCTCTTTTCTCATGACAAAAACACAGTCGTGTGACATGAAGGCCTGAAAAAGGTGTAAAAT
GAGGACAAGAAACAAAGTGG

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MKCPACQHNGTRVLDSRPVDEGRSIRRRRECESCNYRFTTFEKVEEIPLIVVKKEGIREEFSREKMLRGLIKACEKRPVA
LKQLEDICFEIEKELRNQGVSEVKSDMIGEMVMDRLAKIDEVAYVRFASVYRQFKDINVFIDELKDLIKKER

Sequences:

>Translated_152_residues
MKCPACQHNGTRVLDSRPVDEGRSIRRRRECESCNYRFTTFEKVEEIPLIVVKKEGIREEFSREKMLRGLIKACEKRPVA
LKQLEDICFEIEKELRNQGVSEVKSDMIGEMVMDRLAKIDEVAYVRFASVYRQFKDINVFIDELKDLIKKER
>Mature_152_residues
MKCPACQHNGTRVLDSRPVDEGRSIRRRRECESCNYRFTTFEKVEEIPLIVVKKEGIREEFSREKMLRGLIKACEKRPVA
LKQLEDICFEIEKELRNQGVSEVKSDMIGEMVMDRLAKIDEVAYVRFASVYRQFKDINVFIDELKDLIKKER

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=147, Percent_Identity=50.3401360544218, Blast_Score=140, Evalue=4e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_BACLD (Q65GA0)

Other databases:

- EMBL:   AE017333
- EMBL:   CP000002
- RefSeq:   YP_080193.1
- RefSeq:   YP_092607.1
- STRING:   Q65GA0
- EnsemblBacteria:   EBBACT00000057513
- EnsemblBacteria:   EBBACT00000062408
- GeneID:   3028915
- GeneID:   3098633
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi03048
- KEGG:   bli:BL00388
- NMPDR:   fig|279010.5.peg.3412
- eggNOG:   COG1327
- GeneTree:   EBGT00050000001207
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- ProtClustDB:   PRK00464
- BioCyc:   BLIC279010-1:BLI03048-MONOMER
- BioCyc:   BLIC279010:BL00388-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 17963; Mature: 17963

Theoretical pI: Translated: 8.37; Mature: 8.37

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKCPACQHNGTRVLDSRPVDEGRSIRRRRECESCNYRFTTFEKVEEIPLIVVKKEGIREE
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCEEEECCHHHHHH
FSREKMLRGLIKACEKRPVALKQLEDICFEIEKELRNQGVSEVKSDMIGEMVMDRLAKID
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
EVAYVRFASVYRQFKDINVFIDELKDLIKKER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKCPACQHNGTRVLDSRPVDEGRSIRRRRECESCNYRFTTFEKVEEIPLIVVKKEGIREE
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCEEEECCHHHHHH
FSREKMLRGLIKACEKRPVALKQLEDICFEIEKELRNQGVSEVKSDMIGEMVMDRLAKID
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
EVAYVRFASVYRQFKDINVFIDELKDLIKKER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA