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The map label for this gene is lytS [H]

Identifier: 52786770

GI number: 52786770

Start: 2923919

End: 2925703

Strand: Reverse

Name: lytS [H]

Synonym: BLi03040

Alternate gene names: 52786770

Gene position: 2925703-2923919 (Counterclockwise)

Preceding gene: 52786771

Following gene: 52786769

Centisome position: 69.29

GC content: 50.42

Gene sequence:

>1785_bases
ATGGTCCAACTCATGATTATGATGCTGGAGAGAGTGGGGATCATCGTCATTCTGGGCTTTATGTTGGCCCATATGAAGGT
GTTCCGTCAGCACCTACAGCATCCGGAAGGGTATAAGGGCAAGGGAGTTCTCATCTTTATTTTTTCCTTGTTCAGCATCA
TCAGCAACTATACAGGCATTGAAATCCGGGAGCGCGAGATTTTGAACAATGACTGGATTTTCGCAATCGACCCGTCAAGC
TCGATTGCCAATACGAGAATTCTCGGCGTCGAAATCGGCGGCTTGATCGGAGGGCCGTTTGTCGGAGCGGGTGTCGGACT
GCTCTCAGGCATTCACCGTTTTTCACTGGGAGGGACGACGGCTTTGAGCTGCGCGGTTTCTTCACTGCTGGCAGGTGTCA
TTGCGGGTTATATCGGCAGCTTTTTCAGGAATCGGCACCAGATGGTGACACCGCGGGTAGCCGCTCTTGCGGGCATTTGT
ATGGAGGGCCTGCAGATGCTTATGATTCTCGTGCTTGCAAAACCGCAGGCTGAGGCACTTGCGCTTGTTCAGATGATCGG
CATTCCAATGATGATTGTCAACGGGACGGGCAGCTTTATTTTTCTATCGATCATTCAGTCTATTATCCGCAAAGAGGAAC
AGGCGCGGGCCGTTCAGACCCATAAGGTATTTTCGATAGCGGATCAGACGCTTCCTTTTTTCCGCCGGGGACTGAATGAG
GATTCCTGCAAAAGCGCCGCTCTCATTATACACCGCATGACAGGGACGGATGCCGTATCGATTACGGATAGAGAGAACAT
TCTCGCTCATGTCGGAGATGGAGCAGATCATCATATTCCTTCGAAAAATCTGATCACCGGTTTATCGAAAAAAGTCATTC
AAACCGGAAAGGTCATGAAAGTGAAGTCGCGCGATGAAATCGAGTGTGCGCACCGTTCCTGTCCGCTGCAGGCGGCGATC
GTACTGCCGCTCTTCTCCAACCGCGAAACAATCGGCACGCTGAAGCTGTACTTCAAGCACCCGTCCGGTCTTAACCGTGT
GACGGAAGAGCTGGCCGAAGGGCTTGCCATGCTTTTTTCCACTCAGCTAGAACTCGGTGAGGCTGAGCTGCAAAGCAAGC
TTTTGAAAGATGCCGAAATCAAGGCGCTTCAAGCGCAGGTCAATCCGCACTTTTTATTTAATGCCATCCATACGATTTCT
GCTCTGTGCAGGACAGATCCGGAAAAAACGCGAAAACTTCTCTTGCAGCTGAGCGTTTATTTTCGTTCCAATCTGCAGGG
AGCCAGGCAGCTGATGATTCCGCTTTCAAAAGAGCTGAACCATCTGGAAGCCTATTTATCATTGGAGCAGGCCCGATTTC
CGGGCAAGTATCATATTGATTTTCATATCGAGGACGGCCTTGAAAATATGGAAATCCCTCCTTTTATCTTGCAGCTGCTC
GTTGAAAATGCGCTTCGCCATGCATTTCCGAGAAAACAAAAGGTATGCACGGTAAAAGTATCCGCTGTGAGAGAGCGGGA
CGGCGTTTTGATGAAGGTGTCAGACAACGGCAGGGGAATTAATCCGGAGATGCTTGGACAGCTGGGGCAGGCGCCCGCCC
CTTCAAAGGAAGGAAATGGGACGGCGCTTTACAATGTGAACCAGCGGCTCACCGGTTTGTTCGGGCACCAGGCTGCTCTG
CAGATTGCCAGCGAACTTGATAAAGGAACAGAGATATCCTTCAAGATTCCTTTTCAAACCGAAAGAGAGGGGAACAGAGA
TGCTCAAGGTATTAATCGTGGATGA

Upstream 100 bases:

>100_bases
TTAAAAGGTTTTAAAGCCATGCCGTCTCAAAGAGTGAATAAAGAGAGGTATGATAGAATAAGAGCAGATTCCGATTCAGA
AAGAAAGCAAGGGGAAGTAC

Downstream 100 bases:

>100_bases
TGAAATGTTTGCGCGGGACGAGCTGAGATATTTACTAGAGCAGACTGAAGAAGTGGATGCGATTGACGAAGCTGAACATA
TCGAAGAAGCGTTTGACAAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 594; Mature: 594

Protein sequence:

>594_residues
MVQLMIMMLERVGIIVILGFMLAHMKVFRQHLQHPEGYKGKGVLIFIFSLFSIISNYTGIEIREREILNNDWIFAIDPSS
SIANTRILGVEIGGLIGGPFVGAGVGLLSGIHRFSLGGTTALSCAVSSLLAGVIAGYIGSFFRNRHQMVTPRVAALAGIC
MEGLQMLMILVLAKPQAEALALVQMIGIPMMIVNGTGSFIFLSIIQSIIRKEEQARAVQTHKVFSIADQTLPFFRRGLNE
DSCKSAALIIHRMTGTDAVSITDRENILAHVGDGADHHIPSKNLITGLSKKVIQTGKVMKVKSRDEIECAHRSCPLQAAI
VLPLFSNRETIGTLKLYFKHPSGLNRVTEELAEGLAMLFSTQLELGEAELQSKLLKDAEIKALQAQVNPHFLFNAIHTIS
ALCRTDPEKTRKLLLQLSVYFRSNLQGARQLMIPLSKELNHLEAYLSLEQARFPGKYHIDFHIEDGLENMEIPPFILQLL
VENALRHAFPRKQKVCTVKVSAVRERDGVLMKVSDNGRGINPEMLGQLGQAPAPSKEGNGTALYNVNQRLTGLFGHQAAL
QIASELDKGTEISFKIPFQTEREGNRDAQGINRG

Sequences:

>Translated_594_residues
MVQLMIMMLERVGIIVILGFMLAHMKVFRQHLQHPEGYKGKGVLIFIFSLFSIISNYTGIEIREREILNNDWIFAIDPSS
SIANTRILGVEIGGLIGGPFVGAGVGLLSGIHRFSLGGTTALSCAVSSLLAGVIAGYIGSFFRNRHQMVTPRVAALAGIC
MEGLQMLMILVLAKPQAEALALVQMIGIPMMIVNGTGSFIFLSIIQSIIRKEEQARAVQTHKVFSIADQTLPFFRRGLNE
DSCKSAALIIHRMTGTDAVSITDRENILAHVGDGADHHIPSKNLITGLSKKVIQTGKVMKVKSRDEIECAHRSCPLQAAI
VLPLFSNRETIGTLKLYFKHPSGLNRVTEELAEGLAMLFSTQLELGEAELQSKLLKDAEIKALQAQVNPHFLFNAIHTIS
ALCRTDPEKTRKLLLQLSVYFRSNLQGARQLMIPLSKELNHLEAYLSLEQARFPGKYHIDFHIEDGLENMEIPPFILQLL
VENALRHAFPRKQKVCTVKVSAVRERDGVLMKVSDNGRGINPEMLGQLGQAPAPSKEGNGTALYNVNQRLTGLFGHQAAL
QIASELDKGTEISFKIPFQTEREGNRDAQGINRG
>Mature_594_residues
MVQLMIMMLERVGIIVILGFMLAHMKVFRQHLQHPEGYKGKGVLIFIFSLFSIISNYTGIEIREREILNNDWIFAIDPSS
SIANTRILGVEIGGLIGGPFVGAGVGLLSGIHRFSLGGTTALSCAVSSLLAGVIAGYIGSFFRNRHQMVTPRVAALAGIC
MEGLQMLMILVLAKPQAEALALVQMIGIPMMIVNGTGSFIFLSIIQSIIRKEEQARAVQTHKVFSIADQTLPFFRRGLNE
DSCKSAALIIHRMTGTDAVSITDRENILAHVGDGADHHIPSKNLITGLSKKVIQTGKVMKVKSRDEIECAHRSCPLQAAI
VLPLFSNRETIGTLKLYFKHPSGLNRVTEELAEGLAMLFSTQLELGEAELQSKLLKDAEIKALQAQVNPHFLFNAIHTIS
ALCRTDPEKTRKLLLQLSVYFRSNLQGARQLMIPLSKELNHLEAYLSLEQARFPGKYHIDFHIEDGLENMEIPPFILQLL
VENALRHAFPRKQKVCTVKVSAVRERDGVLMKVSDNGRGINPEMLGQLGQAPAPSKEGNGTALYNVNQRLTGLFGHQAAL
QIASELDKGTEISFKIPFQTEREGNRDAQGINRG

Specific function: Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism [H]

COG id: COG3275

COG function: function code T; Putative regulator of cell autolysis

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788723, Length=583, Percent_Identity=33.7907375643225, Blast_Score=316, Evalue=2e-87,
Organism=Escherichia coli, GI1788446, Length=584, Percent_Identity=32.5342465753425, Blast_Score=293, Evalue=2e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR010559
- InterPro:   IPR005467
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF01590 GAF; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 65423; Mature: 65423

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: PS00525 RIBOSOMAL_L6_1 ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQLMIMMLERVGIIVILGFMLAHMKVFRQHLQHPEGYKGKGVLIFIFSLFSIISNYTGI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCC
EIREREILNNDWIFAIDPSSSIANTRILGVEIGGLIGGPFVGAGVGLLSGIHRFSLGGTT
EEEHHHHCCCCCEEEECCCCCCCCCEEEEEEECCHHCCCHHHHHHHHHHHHHHHCCCCHH
ALSCAVSSLLAGVIAGYIGSFFRNRHQMVTPRVAALAGICMEGLQMLMILVLAKPQAEAL
HHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
ALVQMIGIPMMIVNGTGSFIFLSIIQSIIRKEEQARAVQTHKVFSIADQTLPFFRRGLNE
HHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DSCKSAALIIHRMTGTDAVSITDRENILAHVGDGADHHIPSKNLITGLSKKVIQTGKVMK
CHHCHHEEEEEEECCCCEEEEECHHHHHEECCCCCCCCCCCHHHHHHHHHHHHHCCCEEE
VKSRDEIECAHRSCPLQAAIVLPLFSNRETIGTLKLYFKHPSGLNRVTEELAEGLAMLFS
ECCCCHHHHHHCCCCCEEEEEEEEECCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHH
TQLELGEAELQSKLLKDAEIKALQAQVNPHFLFNAIHTISALCRTDPEKTRKLLLQLSVY
HHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
FRSNLQGARQLMIPLSKELNHLEAYLSLEQARFPGKYHIDFHIEDGLENMEIPPFILQLL
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCHHHHHHH
VENALRHAFPRKQKVCTVKVSAVRERDGVLMKVSDNGRGINPEMLGQLGQAPAPSKEGNG
HHHHHHHHCCCCCCEEEEEEEHHHCCCCEEEEECCCCCCCCHHHHHHHCCCCCCCCCCCC
TALYNVNQRLTGLFGHQAALQIASELDKGTEISFKIPFQTEREGNRDAQGINRG
EEEEECCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MVQLMIMMLERVGIIVILGFMLAHMKVFRQHLQHPEGYKGKGVLIFIFSLFSIISNYTGI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCC
EIREREILNNDWIFAIDPSSSIANTRILGVEIGGLIGGPFVGAGVGLLSGIHRFSLGGTT
EEEHHHHCCCCCEEEECCCCCCCCCEEEEEEECCHHCCCHHHHHHHHHHHHHHHCCCCHH
ALSCAVSSLLAGVIAGYIGSFFRNRHQMVTPRVAALAGICMEGLQMLMILVLAKPQAEAL
HHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
ALVQMIGIPMMIVNGTGSFIFLSIIQSIIRKEEQARAVQTHKVFSIADQTLPFFRRGLNE
HHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DSCKSAALIIHRMTGTDAVSITDRENILAHVGDGADHHIPSKNLITGLSKKVIQTGKVMK
CHHCHHEEEEEEECCCCEEEEECHHHHHEECCCCCCCCCCCHHHHHHHHHHHHHCCCEEE
VKSRDEIECAHRSCPLQAAIVLPLFSNRETIGTLKLYFKHPSGLNRVTEELAEGLAMLFS
ECCCCHHHHHHCCCCCEEEEEEEEECCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHH
TQLELGEAELQSKLLKDAEIKALQAQVNPHFLFNAIHTISALCRTDPEKTRKLLLQLSVY
HHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
FRSNLQGARQLMIPLSKELNHLEAYLSLEQARFPGKYHIDFHIEDGLENMEIPPFILQLL
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCHHHHHHH
VENALRHAFPRKQKVCTVKVSAVRERDGVLMKVSDNGRGINPEMLGQLGQAPAPSKEGNG
HHHHHHHHCCCCCCEEEEEEEHHHCCCCEEEEECCCCCCCCHHHHHHHCCCCCCCCCCCC
TALYNVNQRLTGLFGHQAALQIASELDKGTEISFKIPFQTEREGNRDAQGINRG
EEEEECCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]