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The map label for this gene is lytT [H]

Identifier: 52786769

GI number: 52786769

Start: 2923222

End: 2923944

Strand: Reverse

Name: lytT [H]

Synonym: BLi03039

Alternate gene names: 52786769

Gene position: 2923944-2923222 (Counterclockwise)

Preceding gene: 52786770

Following gene: 52786767

Centisome position: 69.24

GC content: 48.27

Gene sequence:

>723_bases
ATGCTCAAGGTATTAATCGTGGATGATGAAATGTTTGCGCGGGACGAGCTGAGATATTTACTAGAGCAGACTGAAGAAGT
GGATGCGATTGACGAAGCTGAACATATCGAAGAAGCGTTTGACAAAATGGCGGATCGCAAACCCGATATCCTCTTCCTGG
ACATCGATCTGTCAGGGGAGAACGGTTTTGACATTGCGCAGCGGCTGAAAAAAATGTCGGCGCCTCCGGCTGTCGTTTTT
GCGACCGCTTATGATGAATATGCGCTGAAAGCATTTGAAGTGGATGCGATTGATTATTTGACAAAGCCGTTTGATGAGGA
GCGAATCAGACAGACAATCCACAAATATAAAAGGATGCGCCCCGGCAAACAGGAGGAGCGGCAGCTTGCAGGCCACCACA
GGCTGGCTCTCAGCATTGACGAATCGATCGTCGTGCTCGATCCCGATGAAATCGTATACGCCGGGTTAGAAGGCGGACAC
GTCACAGTGAAGACTTTTGATCAGGCATACACGGTTCACGATACATTGGTTGTACTCGAACAAAAGCTTTCGCAGACGGC
ATTGATCAGGGTGCACAGAAGTTTTCTCGCAAATATGGATCATATTAAACAGGTCAAACCCTGGTTCAATTCGACATACA
ACCTCCTGATGAAAGACGGCTCCACGATCCCTGTCAGCCGTACATACGCGAAAGAGCTGAAAAAACGGCTGCATATGGTG
TGA

Upstream 100 bases:

>100_bases
TTCGGGCACCAGGCTGCTCTGCAGATTGCCAGCGAACTTGATAAAGGAACAGAGATATCCTTCAAGATTCCTTTTCAAAC
CGAAAGAGAGGGGAACAGAG

Downstream 100 bases:

>100_bases
AAAAATGATCAGCGGCGGTGAAGGGCTTAATTCGTCTTTCACCGCCGTTTTTTAGCTAAAACATGCGCTGGAGCCCGGGG
CGTCCTGCTTCAACGGCGAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MLKVLIVDDEMFARDELRYLLEQTEEVDAIDEAEHIEEAFDKMADRKPDILFLDIDLSGENGFDIAQRLKKMSAPPAVVF
ATAYDEYALKAFEVDAIDYLTKPFDEERIRQTIHKYKRMRPGKQEERQLAGHHRLALSIDESIVVLDPDEIVYAGLEGGH
VTVKTFDQAYTVHDTLVVLEQKLSQTALIRVHRSFLANMDHIKQVKPWFNSTYNLLMKDGSTIPVSRTYAKELKKRLHMV

Sequences:

>Translated_240_residues
MLKVLIVDDEMFARDELRYLLEQTEEVDAIDEAEHIEEAFDKMADRKPDILFLDIDLSGENGFDIAQRLKKMSAPPAVVF
ATAYDEYALKAFEVDAIDYLTKPFDEERIRQTIHKYKRMRPGKQEERQLAGHHRLALSIDESIVVLDPDEIVYAGLEGGH
VTVKTFDQAYTVHDTLVVLEQKLSQTALIRVHRSFLANMDHIKQVKPWFNSTYNLLMKDGSTIPVSRTYAKELKKRLHMV
>Mature_240_residues
MLKVLIVDDEMFARDELRYLLEQTEEVDAIDEAEHIEEAFDKMADRKPDILFLDIDLSGENGFDIAQRLKKMSAPPAVVF
ATAYDEYALKAFEVDAIDYLTKPFDEERIRQTIHKYKRMRPGKQEERQLAGHHRLALSIDESIVVLDPDEIVYAGLEGGH
VTVKTFDQAYTVHDTLVVLEQKLSQTALIRVHRSFLANMDHIKQVKPWFNSTYNLLMKDGSTIPVSRTYAKELKKRLHMV

Specific function: Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism [H]

COG id: COG3279

COG function: function code KT; Response regulator of the LytR/AlgR family

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87082052, Length=250, Percent_Identity=34, Blast_Score=137, Evalue=6e-34,
Organism=Escherichia coli, GI1788724, Length=244, Percent_Identity=30.7377049180328, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1789809, Length=150, Percent_Identity=34.6666666666667, Blast_Score=68, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR007492
- InterPro:   IPR001789 [H]

Pfam domain/function: PF04397 LytTR; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 27738; Mature: 27738

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50930 HTH_LYTTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKVLIVDDEMFARDELRYLLEQTEEVDAIDEAEHIEEAFDKMADRKPDILFLDIDLSGE
CEEEEEECCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCC
NGFDIAQRLKKMSAPPAVVFATAYDEYALKAFEVDAIDYLTKPFDEERIRQTIHKYKRMR
CCHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCC
PGKQEERQLAGHHRLALSIDESIVVLDPDEIVYAGLEGGHVTVKTFDQAYTVHDTLVVLE
CCCHHHHHHHCCCEEEEEECCEEEEECCCCEEEEECCCCEEEEEECCCHHHHHHHHHHHH
QKLSQTALIRVHRSFLANMDHIKQVKPWFNSTYNLLMKDGSTIPVSRTYAKELKKRLHMV
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCHHHEEEECCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLKVLIVDDEMFARDELRYLLEQTEEVDAIDEAEHIEEAFDKMADRKPDILFLDIDLSGE
CEEEEEECCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCC
NGFDIAQRLKKMSAPPAVVFATAYDEYALKAFEVDAIDYLTKPFDEERIRQTIHKYKRMR
CCHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCC
PGKQEERQLAGHHRLALSIDESIVVLDPDEIVYAGLEGGHVTVKTFDQAYTVHDTLVVLE
CCCHHHHHHHCCCEEEEEECCEEEEECCCCEEEEECCCCEEEEEECCCHHHHHHHHHHHH
QKLSQTALIRVHRSFLANMDHIKQVKPWFNSTYNLLMKDGSTIPVSRTYAKELKKRLHMV
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCHHHEEEECCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]