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The map label for this gene is ysbA [H]

Identifier: 52786767

GI number: 52786767

Start: 2920960

End: 2921373

Strand: Reverse

Name: ysbA [H]

Synonym: BLi03037

Alternate gene names: 52786767

Gene position: 2921373-2920960 (Counterclockwise)

Preceding gene: 52786769

Following gene: 52786766

Centisome position: 69.18

GC content: 46.86

Gene sequence:

>414_bases
ATGAAGGGTAAAAAAGAATACGGCTTTTTAACTCAGGCATTTATTTTTGCTGTTATGATGTTTATTTCAAACGGAATCGC
CGCGGTTCTGCCCATCCCGATTCCTCCATCTGTCATCGGTTTGGTGCTGTTGTTTGCATTGCTGTGTACGAAAGTGCTGA
AGCTTGAACAAGTTGAATCGCTCGGCACGGCGCTCACTTCGCTGATCGGCTTTTTGTTCGTTCCGTCGGGAATATCAGTG
ATGAATTCGCTCGGCGTCATGGAGAAATACGGATTGCCGATCGTCCTCGTGATTTTCCTGGCCACCGTCATTCTGCTTGC
AGCGACAGGATTGTTTTCACAGTTCATTCTGTCTGTCGGCAAAAAGGACCGTCAAGACACACGAGTTGAACCAGCCAAAA
AAACAGCATCTTGA

Upstream 100 bases:

>100_bases
TGCAATTGAGGGGCCGTATCCGGCAAGTTATTTTGAAAACGCTTTTTTGGGGAGGCTCTTTTTATATAATGAACCCAACA
CAGCCAAAGAGGTGAACGAA

Downstream 100 bases:

>100_bases
ATCAATAGGAGGTTCTTTACGCTATGACACCTTATTTCGGTATCGTCGTTTCACTGGCCGCATTTGGCACCGGCACTTTT
TTATTTAAAAAATCAAATGG

Product: murein hydrolase regulator LrgA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 137; Mature: 137

Protein sequence:

>137_residues
MKGKKEYGFLTQAFIFAVMMFISNGIAAVLPIPIPPSVIGLVLLFALLCTKVLKLEQVESLGTALTSLIGFLFVPSGISV
MNSLGVMEKYGLPIVLVIFLATVILLAATGLFSQFILSVGKKDRQDTRVEPAKKTAS

Sequences:

>Translated_137_residues
MKGKKEYGFLTQAFIFAVMMFISNGIAAVLPIPIPPSVIGLVLLFALLCTKVLKLEQVESLGTALTSLIGFLFVPSGISV
MNSLGVMEKYGLPIVLVIFLATVILLAATGLFSQFILSVGKKDRQDTRVEPAKKTAS
>Mature_137_residues
MKGKKEYGFLTQAFIFAVMMFISNGIAAVLPIPIPPSVIGLVLLFALLCTKVLKLEQVESLGTALTSLIGFLFVPSGISV
MNSLGVMEKYGLPIVLVIFLATVILLAATGLFSQFILSVGKKDRQDTRVEPAKKTAS

Specific function: Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell

COG id: COG1380

COG function: function code R; Putative effector of murein hydrolase LrgA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CidA/LrgA family. LrgA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005538 [H]

Pfam domain/function: PF03788 LrgA [H]

EC number: NA

Molecular weight: Translated: 14677; Mature: 14677

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGKKEYGFLTQAFIFAVMMFISNGIAAVLPIPIPPSVIGLVLLFALLCTKVLKLEQVES
CCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LGTALTSLIGFLFVPSGISVMNSLGVMEKYGLPIVLVIFLATVILLAATGLFSQFILSVG
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
KKDRQDTRVEPAKKTAS
CCCCCCCCCCCHHCCCC
>Mature Secondary Structure
MKGKKEYGFLTQAFIFAVMMFISNGIAAVLPIPIPPSVIGLVLLFALLCTKVLKLEQVES
CCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LGTALTSLIGFLFVPSGISVMNSLGVMEKYGLPIVLVIFLATVILLAATGLFSQFILSVG
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
KKDRQDTRVEPAKKTAS
CCCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12721630 [H]