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The map label for this gene is sdhB [H]

Identifier: 52786723

GI number: 52786723

Start: 2872716

End: 2873480

Strand: Reverse

Name: sdhB [H]

Synonym: BLi02992

Alternate gene names: 52786723

Gene position: 2873480-2872716 (Counterclockwise)

Preceding gene: 52786724

Following gene: 52786722

Centisome position: 68.05

GC content: 49.93

Gene sequence:

>765_bases
ATGAGTGAAAATAAGACAATCAAGTTTATCATCACTCGTCAGGATACATCGGATTCTAATCCTTACCAGGAAGAGTTTGA
AATTCCATACCGTCCGAATATGAACGTGATTTCCGCTTTGATGGAAATCAGAAGGAACCCGGTGAATGCAAAGGGAGAAA
AAACGTCGCCGATTGCTTGGGATATGAACTGTCTCGAGGAAGTGTGCGGCGCTTGCTCCATGGTGATCAACGGCAAGCCG
AGACAGTCCTGTACAGCGCTGATCGACCAGCTTGAGCAGCCGATCCGCCTTGAACCGATGAAAACATTCCCGGTTGTCCG
CGACCTTCAAGTGGATCGGAGCCGCATGTTTGATTCGTTAAAGAAAGTCAAAGCATGGGTGCCGATCGACGGCACATATG
ATCTCGGACCGGGACCGAGAATGCCTGAAAGAAGACGTCAGTGGGCTTATGAGCTGTCAAAATGCATGACTTGCGGCGTG
TGTCTTGAAGCTTGTCCGAACGTGAACGATAAAACAAACTTTATGGGACCTGCACCGCTCTCGCAAGTTCGCTTATTCAA
CACCCATCCGACGGGAGCGATGAACAAATCTGAACGGCTTGAAGCGATTATGGGAGACGGCGGACTGGCCGAATGCGGCA
ACTCGCAAAACTGCGTGCAGTCGTGTCCGAAAGGCATCCCGCTCACAACCTCAATCGCTGCATTAAACAGGGATACGACC
GTTCAGGCGTTTAAAAACTTCTTCGGAAGCGACAACACGGAATAA

Upstream 100 bases:

>100_bases
CAGGCGATTTTGAAGCCCCGAAATTCCATTATGAGGATGTCGATGTTTCATTAATCGCACCGCGTAAACGGGATTACTCG
AAGAAAAAGGTGGCGAAATC

Downstream 100 bases:

>100_bases
CACGAAAAAACGCACCTCTTCAAACCGAAGAGGTGTTTTCATGATCAAAGGGGATGAAAACATTGAAATTGCCGGGATAT
ATCGAAGAACCGTTTGACAC

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MSENKTIKFIITRQDTSDSNPYQEEFEIPYRPNMNVISALMEIRRNPVNAKGEKTSPIAWDMNCLEEVCGACSMVINGKP
RQSCTALIDQLEQPIRLEPMKTFPVVRDLQVDRSRMFDSLKKVKAWVPIDGTYDLGPGPRMPERRRQWAYELSKCMTCGV
CLEACPNVNDKTNFMGPAPLSQVRLFNTHPTGAMNKSERLEAIMGDGGLAECGNSQNCVQSCPKGIPLTTSIAALNRDTT
VQAFKNFFGSDNTE

Sequences:

>Translated_254_residues
MSENKTIKFIITRQDTSDSNPYQEEFEIPYRPNMNVISALMEIRRNPVNAKGEKTSPIAWDMNCLEEVCGACSMVINGKP
RQSCTALIDQLEQPIRLEPMKTFPVVRDLQVDRSRMFDSLKKVKAWVPIDGTYDLGPGPRMPERRRQWAYELSKCMTCGV
CLEACPNVNDKTNFMGPAPLSQVRLFNTHPTGAMNKSERLEAIMGDGGLAECGNSQNCVQSCPKGIPLTTSIAALNRDTT
VQAFKNFFGSDNTE
>Mature_253_residues
SENKTIKFIITRQDTSDSNPYQEEFEIPYRPNMNVISALMEIRRNPVNAKGEKTSPIAWDMNCLEEVCGACSMVINGKPR
QSCTALIDQLEQPIRLEPMKTFPVVRDLQVDRSRMFDSLKKVKAWVPIDGTYDLGPGPRMPERRRQWAYELSKCMTCGVC
LEACPNVNDKTNFMGPAPLSQVRLFNTHPTGAMNKSERLEAIMGDGGLAECGNSQNCVQSCPKGIPLTTSIAALNRDTTV
QAFKNFFGSDNTE

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=242, Percent_Identity=26.4462809917355, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1790596, Length=250, Percent_Identity=25.2, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI1786943, Length=240, Percent_Identity=27.9166666666667, Blast_Score=82, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6322987, Length=246, Percent_Identity=25.2032520325203, Blast_Score=76, Evalue=4e-15,
Organism=Drosophila melanogaster, GI17137106, Length=238, Percent_Identity=25.2100840336134, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24643156, Length=234, Percent_Identity=26.4957264957265, Blast_Score=75, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 28409; Mature: 28278

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.3 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
9.1 %Cys+Met (Translated Protein)
4.3 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
8.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSENKTIKFIITRQDTSDSNPYQEEFEIPYRPNMNVISALMEIRRNPVNAKGEKTSPIAW
CCCCCEEEEEEEECCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEE
DMNCLEEVCGACSMVINGKPRQSCTALIDQLEQPIRLEPMKTFPVVRDLQVDRSRMFDSL
CHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCHHCCHHHHHHHHHHHHHHHH
KKVKAWVPIDGTYDLGPGPRMPERRRQWAYELSKCMTCGVCLEACPNVNDKTNFMGPAPL
HHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCH
SQVRLFNTHPTGAMNKSERLEAIMGDGGLAECGNSQNCVQSCPKGIPLTTSIAALNRDTT
HHEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHCCCHH
VQAFKNFFGSDNTE
HHHHHHHHCCCCCC
>Mature Secondary Structure 
SENKTIKFIITRQDTSDSNPYQEEFEIPYRPNMNVISALMEIRRNPVNAKGEKTSPIAW
CCCCEEEEEEEECCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEE
DMNCLEEVCGACSMVINGKPRQSCTALIDQLEQPIRLEPMKTFPVVRDLQVDRSRMFDSL
CHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCHHCCHHHHHHHHHHHHHHHH
KKVKAWVPIDGTYDLGPGPRMPERRRQWAYELSKCMTCGVCLEACPNVNDKTNFMGPAPL
HHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCH
SQVRLFNTHPTGAMNKSERLEAIMGDGGLAECGNSQNCVQSCPKGIPLTTSIAALNRDTT
HHEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHCCCHH
VQAFKNFFGSDNTE
HHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3027051; 8969504; 9384377; 3114423 [H]