Click here to switch to the map view.

The map label for this gene is pheA [H]

Identifier: 52786649

GI number: 52786649

Start: 2804429

End: 2805298

Strand: Reverse

Name: pheA [H]

Synonym: BLi02917

Alternate gene names: 52786649

Gene position: 2805298-2804429 (Counterclockwise)

Preceding gene: 52786650

Following gene: 52786646

Centisome position: 66.43

GC content: 47.59

Gene sequence:

>870_bases
ATGACATATATCATGAGTATGAGAGTAGGTTATTTAGGTCCAGAAGCAACTTTTACGCACCTTGCCGTCTGCTCCTGCTT
TTCAGATGCAGACCAGCAAGCATTTAACACGATACCGGCCTGCATGGATGCGGCGATGAACGGGGAGATCGATCTGGCTG
TCGTCCCGCTTGAAAATGCGATTGAAGGATCGGTGAATCTGACAATAGACTACTTAATTCACGAACAGCCTCTTTATATT
GTCGGAGAAATCACCGCTCCCATCCGTCAGCATTTGCTTGTGCATCCTACCAGAAAAGAGGCTTGGGAAGACATTCAGAA
GGTTTATTCCCATTCCCATGCCATCGCGCAATGCCATAAATTTTTGCACAGCCGGTTCCGCTCCATTCCGTTTGAATATG
CGACATCCACCGGAGCAGCTGCAAAATACGTGAGCGAAAATCCGGAAGAGAACATCGGCGTGATCGCCAATGAAATGGCA
GCAGATACTTACGGATTAGACATCGTCAAAAGAGATGTGCATGACTATGAATACAATCACACGAGATTTGTGATGCTTCA
TCCGGATCGCGAGGCATCCCCTCCGGTCAACCCTCAACTCAAGGGAAGACCGAAAACGACTTTGCTGGTGACCCTTCCTT
CGGACAGATCGGGAGCTCTCCACCAAGTGCTGTCGGCTTTCGCCTGGAGAAATTTGAATCTTTCTAAAATTGAATCGCGG
CCGACAAAAACCGGTCTCGGCAATTATTTCTTCATTATTGATATTGAAATGGCCCTGGATGACGTGCTGATTCCAGGTGC
AATAGCTGAGCTTGAAGCTTTGGGCTGCAAGGTGAAAATGCTCGGTGCCTACAACGCATATACACTATAA

Upstream 100 bases:

>100_bases
GAGGCATGGATGAAAATATCGATTTGCTGATGAACAAATTAAGAAAGCTGGAATTCGTAGAAAAGGTCGAAATACTAGGT
TCGGGCGCTTAAGGGAGAGA

Downstream 100 bases:

>100_bases
AAGAAAGGTCCTTTGCGCTGATAACGGCAAAGGACCTTTTCTTTTATTCGGGAATGAGGATGCCCGCTTTTTGCAGGGCG
CCGCAAGCTTGTTCGATCTT

Product: prephenate dehydratase

Products: NA

Alternate protein names: PDT [H]

Number of amino acids: Translated: 289; Mature: 288

Protein sequence:

>289_residues
MTYIMSMRVGYLGPEATFTHLAVCSCFSDADQQAFNTIPACMDAAMNGEIDLAVVPLENAIEGSVNLTIDYLIHEQPLYI
VGEITAPIRQHLLVHPTRKEAWEDIQKVYSHSHAIAQCHKFLHSRFRSIPFEYATSTGAAAKYVSENPEENIGVIANEMA
ADTYGLDIVKRDVHDYEYNHTRFVMLHPDREASPPVNPQLKGRPKTTLLVTLPSDRSGALHQVLSAFAWRNLNLSKIESR
PTKTGLGNYFFIIDIEMALDDVLIPGAIAELEALGCKVKMLGAYNAYTL

Sequences:

>Translated_289_residues
MTYIMSMRVGYLGPEATFTHLAVCSCFSDADQQAFNTIPACMDAAMNGEIDLAVVPLENAIEGSVNLTIDYLIHEQPLYI
VGEITAPIRQHLLVHPTRKEAWEDIQKVYSHSHAIAQCHKFLHSRFRSIPFEYATSTGAAAKYVSENPEENIGVIANEMA
ADTYGLDIVKRDVHDYEYNHTRFVMLHPDREASPPVNPQLKGRPKTTLLVTLPSDRSGALHQVLSAFAWRNLNLSKIESR
PTKTGLGNYFFIIDIEMALDDVLIPGAIAELEALGCKVKMLGAYNAYTL
>Mature_288_residues
TYIMSMRVGYLGPEATFTHLAVCSCFSDADQQAFNTIPACMDAAMNGEIDLAVVPLENAIEGSVNLTIDYLIHEQPLYIV
GEITAPIRQHLLVHPTRKEAWEDIQKVYSHSHAIAQCHKFLHSRFRSIPFEYATSTGAAAKYVSENPEENIGVIANEMAA
DTYGLDIVKRDVHDYEYNHTRFVMLHPDREASPPVNPQLKGRPKTTLLVTLPSDRSGALHQVLSAFAWRNLNLSKIESRP
TKTGLGNYFFIIDIEMALDDVLIPGAIAELEALGCKVKMLGAYNAYTL

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=294, Percent_Identity=31.9727891156463, Blast_Score=125, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6324013, Length=275, Percent_Identity=25.8181818181818, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF00800 PDT [H]

EC number: =4.2.1.51 [H]

Molecular weight: Translated: 32168; Mature: 32037

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS00857 PREPHENATE_DEHYDR_1 ; PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYIMSMRVGYLGPEATFTHLAVCSCFSDADQQAFNTIPACMDAAMNGEIDLAVVPLENA
CEEEEEEEECCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCC
IEGSVNLTIDYLIHEQPLYIVGEITAPIRQHLLVHPTRKEAWEDIQKVYSHSHAIAQCHK
CCCCEEEEEEEEEECCCEEEEEECCHHHHHCEEECCCHHHHHHHHHHHHHHHHHHHHHHH
FLHSRFRSIPFEYATSTGAAAKYVSENPEENIGVIANEMAADTYGLDIVKRDVHDYEYNH
HHHHHHHCCCHHHCCCCCHHHHHHCCCCCCCCCEEEHHHHCCHHCHHHHHHHHHCCCCCC
TRFVMLHPDREASPPVNPQLKGRPKTTLLVTLPSDRSGALHQVLSAFAWRNLNLSKIESR
EEEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCHHHHCCC
PTKTGLGNYFFIIDIEMALDDVLIPGAIAELEALGCKVKMLGAYNAYTL
CCCCCCCCEEEEEEEEEHHHHEECCCHHHHHHHHCCEEEEEECCCCCCC
>Mature Secondary Structure 
TYIMSMRVGYLGPEATFTHLAVCSCFSDADQQAFNTIPACMDAAMNGEIDLAVVPLENA
EEEEEEEECCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCC
IEGSVNLTIDYLIHEQPLYIVGEITAPIRQHLLVHPTRKEAWEDIQKVYSHSHAIAQCHK
CCCCEEEEEEEEEECCCEEEEEECCHHHHHCEEECCCHHHHHHHHHHHHHHHHHHHHHHH
FLHSRFRSIPFEYATSTGAAAKYVSENPEENIGVIANEMAADTYGLDIVKRDVHDYEYNH
HHHHHHHCCCHHHCCCCCHHHHHHCCCCCCCCCEEEHHHHCCHHCHHHHHHHHHCCCCCC
TRFVMLHPDREASPPVNPQLKGRPKTTLLVTLPSDRSGALHQVLSAFAWRNLNLSKIESR
EEEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCHHHHCCC
PTKTGLGNYFFIIDIEMALDDVLIPGAIAELEALGCKVKMLGAYNAYTL
CCCCCCCCEEEEEEEEEHHHHEECCCHHHHHHHHCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2537815; 9384377; 8444804 [H]