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The map label for this gene is yrvI

Identifier: 52786618

GI number: 52786618

Start: 2775546

End: 2775989

Strand: Reverse

Name: yrvI

Synonym: BLi02886

Alternate gene names: 52786618

Gene position: 2775989-2775546 (Counterclockwise)

Preceding gene: 52786619

Following gene: 52786616

Centisome position: 65.74

GC content: 49.55

Gene sequence:

>444_bases
ATGAGATTAGTTGTTCAGCGCGTCACAGATGCAAGCGTTTCGGTAGGAGGCGAGACTGTCGGCGAAATCGGCCTCGGCTT
GATGGTGCTTGTCGGCGTGACGCACGAAGATACGAGCGAGGATGCCGCATATTTGGCGGAGAAGCTTGTCAATCTGCGAA
TTTTTGAGGATGAAGGCGAAAAGATGAACCTGTCGCTTTTAGATGTCGGGGGCTCCGTTTTATCGGTTTCTCAGTTTACC
TTGTACGGCGACACGAAAAAAGGAAGACGGCCGAATTTTACAAAAGCGGCAAAGCCCGATCAGGCGCTTCAATTGTACGA
AGAGTGGAACAGCATGCTTCGCGCAAAAGGCGTCACTGTCGAAACGGGAAGATTTGGAGAAATGATGGATGTCAAGCTGA
CAAATTCGGGTCCCGTCACGTTTATTATGGATTCGAAAGCATAA

Upstream 100 bases:

>100_bases
ATTCAAAATATTAACCATTTGCATAAAGTAGTTGAACGGATTAAGCAGATCAAAGATATTTACTCCGTGCGCAGGGTGAT
GAATTAGGAGGAAAAGCGTC

Downstream 100 bases:

>100_bases
AAAGCTCCCGATTGGGAGCTTTTTAAATTAGTCAAAATAGTTTTCTAGACCGCTTCTGATGCCGTCTGTCACTCTTTCTC
TGTAAGCGTTCGTGCTGACT

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 147; Mature: 147

Protein sequence:

>147_residues
MRLVVQRVTDASVSVGGETVGEIGLGLMVLVGVTHEDTSEDAAYLAEKLVNLRIFEDEGEKMNLSLLDVGGSVLSVSQFT
LYGDTKKGRRPNFTKAAKPDQALQLYEEWNSMLRAKGVTVETGRFGEMMDVKLTNSGPVTFIMDSKA

Sequences:

>Translated_147_residues
MRLVVQRVTDASVSVGGETVGEIGLGLMVLVGVTHEDTSEDAAYLAEKLVNLRIFEDEGEKMNLSLLDVGGSVLSVSQFT
LYGDTKKGRRPNFTKAAKPDQALQLYEEWNSMLRAKGVTVETGRFGEMMDVKLTNSGPVTFIMDSKA
>Mature_147_residues
MRLVVQRVTDASVSVGGETVGEIGLGLMVLVGVTHEDTSEDAAYLAEKLVNLRIFEDEGEKMNLSLLDVGGSVLSVSQFT
LYGDTKKGRRPNFTKAAKPDQALQLYEEWNSMLRAKGVTVETGRFGEMMDVKLTNSGPVTFIMDSKA

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family

Homologues:

Organism=Homo sapiens, GI30795227, Length=150, Percent_Identity=42, Blast_Score=112, Evalue=8e-26,
Organism=Escherichia coli, GI1790320, Length=143, Percent_Identity=49.6503496503497, Blast_Score=139, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI115533292, Length=149, Percent_Identity=46.3087248322148, Blast_Score=121, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6319982, Length=148, Percent_Identity=43.2432432432432, Blast_Score=118, Evalue=4e-28,
Organism=Drosophila melanogaster, GI281361569, Length=147, Percent_Identity=42.1768707482993, Blast_Score=112, Evalue=9e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DTD_BACLD (Q65GR0)

Other databases:

- EMBL:   AE017333
- EMBL:   CP000002
- RefSeq:   YP_080029.1
- RefSeq:   YP_092447.1
- HSSP:   O66742
- ProteinModelPortal:   Q65GR0
- SMR:   Q65GR0
- STRING:   Q65GR0
- EnsemblBacteria:   EBBACT00000055488
- EnsemblBacteria:   EBBACT00000059245
- GeneID:   3029117
- GeneID:   3098203
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi02886
- KEGG:   bli:BL01123
- NMPDR:   fig|279010.5.peg.3213
- eggNOG:   COG1490
- GeneTree:   EBGT00050000002392
- HOGENOM:   HBG286048
- OMA:   MKAVIQR
- ProtClustDB:   PRK05273
- BioCyc:   BLIC279010-1:BLI02886-MONOMER
- BioCyc:   BLIC279010:BL01123-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00518
- InterPro:   IPR003732
- Gene3D:   G3DSA:3.50.80.10
- PANTHER:   PTHR10472
- TIGRFAMs:   TIGR00256

Pfam domain/function: PF02580 Tyr_Deacylase; SSF69500 DTyrtRNA_deacyls

EC number: NA

Molecular weight: Translated: 16006; Mature: 16006

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: ACT_SITE 80-80

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLVVQRVTDASVSVGGETVGEIGLGLMVLVGVTHEDTSEDAAYLAEKLVNLRIFEDEGE
CCEEEEECCCCCEECCCCHHHHHHHCEEEEEECCCCCCCHHHHHHHHHHHEEEEECCCCC
KMNLSLLDVGGSVLSVSQFTLYGDTKKGRRPNFTKAAKPDQALQLYEEWNSMLRAKGVTV
EEEEEEEECCCCEEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEE
ETGRFGEMMDVKLTNSGPVTFIMDSKA
ECCCCCCEEEEEECCCCCEEEEECCCC
>Mature Secondary Structure
MRLVVQRVTDASVSVGGETVGEIGLGLMVLVGVTHEDTSEDAAYLAEKLVNLRIFEDEGE
CCEEEEECCCCCEECCCCHHHHHHHCEEEEEECCCCCCCHHHHHHHHHHHEEEEECCCCC
KMNLSLLDVGGSVLSVSQFTLYGDTKKGRRPNFTKAAKPDQALQLYEEWNSMLRAKGVTV
EEEEEEEECCCCEEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEE
ETGRFGEMMDVKLTNSGPVTFIMDSKA
ECCCCCCEEEEEECCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA