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The map label for this gene is hxlB [H]

Identifier: 52786539

GI number: 52786539

Start: 2688835

End: 2689245

Strand: Reverse

Name: hxlB [H]

Synonym: BLi02804

Alternate gene names: 52786539

Gene position: 2689245-2688835 (Counterclockwise)

Preceding gene: 52786540

Following gene: 52786538

Centisome position: 63.69

GC content: 42.58

Gene sequence:

>411_bases
ATGGGGAAGTCATTTGCTATGAGATTAATGCACCTGGGTATCAATGCATTTGTAACAGGAGAAACCGTAACACCTGCATT
TACCGAAAACGACTTGCTTATCGTGGGCACAGGATCAGGGAAAACAGAAAGTTTGCTTCATATGGCGGAAAAGGCAAAAG
ATATCGGAGGCACTGTAGCGGCAGTTACGACCTCTTCAGATTCGCCAATCGCTGAAATAGCTGATCTGATCCTGCAGCTG
CCGGGTTCACCCAAGGATCAAACGACGGGCAGTAAACAGACTATACAACCGATGGGATCGCTTTTTGAACAGACTCTTTT
ATTGATTTATGATGCTATCATATTGCGAATAATGGAAATAAAAGGGCTGAATACTCATAACATGTACGCAAATCATGCAA
ATCTTGAATAA

Upstream 100 bases:

>100_bases
ATGCAACGTCTCAAACTCAAGCGGAAGGAATAGAGAACTTCATATCCAGTATCATGTCTTCTGAAAAAGTGTTTGTTACG
GTGCAGGTCGTTCCGGTTTA

Downstream 100 bases:

>100_bases
ATAAACCTTCATGTAAAGAAAATCACCATCCGCTATCTCGGACGGTGATTTTTTGTATACCAACCGGTTTTTAACATAAC
ATTTACATCTTTATTATGAT

Product: HxlB

Products: NA

Alternate protein names: 6-phospho-3-hexuloisomerase; PHI [H]

Number of amino acids: Translated: 136; Mature: 135

Protein sequence:

>136_residues
MGKSFAMRLMHLGINAFVTGETVTPAFTENDLLIVGTGSGKTESLLHMAEKAKDIGGTVAAVTTSSDSPIAEIADLILQL
PGSPKDQTTGSKQTIQPMGSLFEQTLLLIYDAIILRIMEIKGLNTHNMYANHANLE

Sequences:

>Translated_136_residues
MGKSFAMRLMHLGINAFVTGETVTPAFTENDLLIVGTGSGKTESLLHMAEKAKDIGGTVAAVTTSSDSPIAEIADLILQL
PGSPKDQTTGSKQTIQPMGSLFEQTLLLIYDAIILRIMEIKGLNTHNMYANHANLE
>Mature_135_residues
GKSFAMRLMHLGINAFVTGETVTPAFTENDLLIVGTGSGKTESLLHMAEKAKDIGGTVAAVTTSSDSPIAEIADLILQLP
GSPKDQTTGSKQTIQPMGSLFEQTLLLIYDAIILRIMEIKGLNTHNMYANHANLE

Specific function: Catalyzes the isomerization between 3-hexulose 6- phosphate and fructose 6-phosphate. Together with hxlA, may act as a formaldehyde detoxification system [H]

COG id: COG0794

COG function: function code M; Predicted sugar phosphate isomerase involved in capsule formation

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017552
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: =5.3.1.27 [H]

Molecular weight: Translated: 14545; Mature: 14414

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKSFAMRLMHLGINAFVTGETVTPAFTENDLLIVGTGSGKTESLLHMAEKAKDIGGTVA
CCHHHHHHHHHCCCCEEEECCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEE
AVTTSSDSPIAEIADLILQLPGSPKDQTTGSKQTIQPMGSLFEQTLLLIYDAIILRIMEI
EEEECCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGLNTHNMYANHANLE
CCCCCCCEECCCCCCC
>Mature Secondary Structure 
GKSFAMRLMHLGINAFVTGETVTPAFTENDLLIVGTGSGKTESLLHMAEKAKDIGGTVA
CHHHHHHHHHCCCCEEEECCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEE
AVTTSSDSPIAEIADLILQLPGSPKDQTTGSKQTIQPMGSLFEQTLLLIYDAIILRIMEI
EEEECCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGLNTHNMYANHANLE
CCCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7704255; 8969502; 9384377; 7921238 [H]