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The map label for this gene is hemB [H]

Identifier: 52786538

GI number: 52786538

Start: 2688000

End: 2688203

Strand: Reverse

Name: hemB [H]

Synonym: BLi02803

Alternate gene names: 52786538

Gene position: 2688203-2688000 (Counterclockwise)

Preceding gene: 52786539

Following gene: 52786537

Centisome position: 63.66

GC content: 41.67

Gene sequence:

>204_bases
ATGCGAAATTCTCTCCAGATTCCGCTGGTTTCATATCAAGTAAGCGGAGAATATGCCCAAATAAAAGCCGCATCGCAAAA
CGGCTGGATTGACGAAAAAAATACAGTGTTGGAAAGCATGCTTGCGATGAAGAGGGCCGGTGCGGATCTTATTGTTACAT
ATTTTGCAAAAGATATAGCAAAATTTCTTCGGGAGGAATCATGA

Upstream 100 bases:

>100_bases
AAGGGGATAAGCAAATGCCATTATTACGTTTCGATCTAATAGAAGGCCGTGATGAACAAGCATTAAACCTGGTCTGCCTT
ATTTAGACATCATCAGGGAT

Downstream 100 bases:

>100_bases
AACGGGCAGCGATCATATTCATTCGATTCTACCAAAAGGCGATATCCCCTCTTTTCCCGCCGACTTGCAGATTTTATCCA
ACATGCTCCAACTATGGGCT

Product: hypothetical protein

Products: NA

Alternate protein names: ALAD; ALADH; Porphobilinogen synthase [H]

Number of amino acids: Translated: 67; Mature: 67

Protein sequence:

>67_residues
MRNSLQIPLVSYQVSGEYAQIKAASQNGWIDEKNTVLESMLAMKRAGADLIVTYFAKDIAKFLREES

Sequences:

>Translated_67_residues
MRNSLQIPLVSYQVSGEYAQIKAASQNGWIDEKNTVLESMLAMKRAGADLIVTYFAKDIAKFLREES
>Mature_67_residues
MRNSLQIPLVSYQVSGEYAQIKAASQNGWIDEKNTVLESMLAMKRAGADLIVTYFAKDIAKFLREES

Specific function: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen [H]

COG id: COG0113

COG function: function code H; Delta-aminolevulinic acid dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ALADH family [H]

Homologues:

Organism=Escherichia coli, GI87081728, Length=66, Percent_Identity=56.0606060606061, Blast_Score=73, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001731
- InterPro:   IPR013785 [H]

Pfam domain/function: PF00490 ALAD [H]

EC number: =4.2.1.24 [H]

Molecular weight: Translated: 7540; Mature: 7540

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNSLQIPLVSYQVSGEYAQIKAASQNGWIDEKNTVLESMLAMKRAGADLIVTYFAKDIA
CCCCCCCEEEEEEECCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHH
KFLREES
HHHHCCC
>Mature Secondary Structure
MRNSLQIPLVSYQVSGEYAQIKAASQNGWIDEKNTVLESMLAMKRAGADLIVTYFAKDIA
CCCCCCCEEEEEEECCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHH
KFLREES
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]