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The map label for this gene is comGA [H]

Identifier: 52786386

GI number: 52786386

Start: 2556942

End: 2557955

Strand: Reverse

Name: comGA [H]

Synonym: BLi02648

Alternate gene names: 52786386

Gene position: 2557955-2556942 (Counterclockwise)

Preceding gene: 52786387

Following gene: 52786385

Centisome position: 60.58

GC content: 47.44

Gene sequence:

>1014_bases
ATGAAGGCGTCAGACATTCATATTGTTCCCGGTGAAAAAGAGGCGGTGGTACGCTTCAGGATTGATGACGAACTGTTTCA
AAAAGACGGATTAACGAGAAATGAGTGCTCTAGACTCATTTCTCACTTTAAATTTCTTTCTTCGATGGACATTGGCGAGA
GACGGCTGCCGCAAAGCGGGGCTTTAACTCTTTATATCAACCGTGAGCCCGTTCATTTAAGGATGTCCACTCTGCCCACC
ATCCATGATGAAAGCTTGGTCATCAGGCTTCTTCCCAAGATGAGCAGCAAGCCGCTCACAAAGCTCTCATTGTTCCCGAG
TGCAACATTCAAGCTGCTGTCTTTTCTGAAGCATTCCCACGGATTAATGCTTTTCACCGGCCCGACAGGCTCGGGAAAAA
CGACAACACTCTATTCTTTAATTGACTACGCCAAGCGGCATTTTAAGCGAAATATCATTACGTTGGAAGACCCGGTCGAA
TCAAGAAGCGAAAACATTTTGCAAGTACAAGTGAACGAAAAAGCGGGCATGACTTATTCTGCGGGGTTGAAGGCGGTGCT
GCGCCACGATCCGGACATGATCATCCTAGGGGAAATTCGCGATGCCGAAACAGCCCAAATCGCAGTCAGGGCAGCTTTGA
CGGGACACCTTGTTCTATCGAGCATGCATGCGAAAAATGCTAAAGGTGCGATATACAGGCTGCTCGAGCTCGGCGTTGAT
ATGACAGAAATTGAACAAACATTGGTCGCAGTCAGCGCCCAGCGTCTTGTCGATATCGTCTGTCCGTTTTGCGGCGACAG
CTGCACTTTGTATTGCAGATTGTCGAGACCAGTTAGAAGAGCAAGCGTCTTTGAACTTTTGTACGGAAAAAGCCTTAATC
TCTGCATCGAAGAAGCAAAAGGCAGATGCGGTGGCATCAAAACAGACACCTTAAAAATGCTGATCCGCAAGGGAATAGCA
CTCGGATATCTGCCGTCGAAAACTTATGAACGCTGGATAGGCCATGAAGATTAA

Upstream 100 bases:

>100_bases
CTTCCGATGGTTTTCGTATAAACTGCGCTTAGAAAGGAGGCGCAATGGTTTGTACACGATCGAATCATTAAGCGGAAGAT
TAATTGACGAGGCATATAGA

Downstream 100 bases:

>100_bases
AATGAAGTGGCCTGTCCGGGAACAGGCGGACCTTCTGAAAAAACTAGGAGACATGATGCAGAGTGGCTATACGATTTTGG
ATGCTTTAAGTATGCTGAAA

Product: ComGA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MKASDIHIVPGEKEAVVRFRIDDELFQKDGLTRNECSRLISHFKFLSSMDIGERRLPQSGALTLYINREPVHLRMSTLPT
IHDESLVIRLLPKMSSKPLTKLSLFPSATFKLLSFLKHSHGLMLFTGPTGSGKTTTLYSLIDYAKRHFKRNIITLEDPVE
SRSENILQVQVNEKAGMTYSAGLKAVLRHDPDMIILGEIRDAETAQIAVRAALTGHLVLSSMHAKNAKGAIYRLLELGVD
MTEIEQTLVAVSAQRLVDIVCPFCGDSCTLYCRLSRPVRRASVFELLYGKSLNLCIEEAKGRCGGIKTDTLKMLIRKGIA
LGYLPSKTYERWIGHED

Sequences:

>Translated_337_residues
MKASDIHIVPGEKEAVVRFRIDDELFQKDGLTRNECSRLISHFKFLSSMDIGERRLPQSGALTLYINREPVHLRMSTLPT
IHDESLVIRLLPKMSSKPLTKLSLFPSATFKLLSFLKHSHGLMLFTGPTGSGKTTTLYSLIDYAKRHFKRNIITLEDPVE
SRSENILQVQVNEKAGMTYSAGLKAVLRHDPDMIILGEIRDAETAQIAVRAALTGHLVLSSMHAKNAKGAIYRLLELGVD
MTEIEQTLVAVSAQRLVDIVCPFCGDSCTLYCRLSRPVRRASVFELLYGKSLNLCIEEAKGRCGGIKTDTLKMLIRKGIA
LGYLPSKTYERWIGHED
>Mature_337_residues
MKASDIHIVPGEKEAVVRFRIDDELFQKDGLTRNECSRLISHFKFLSSMDIGERRLPQSGALTLYINREPVHLRMSTLPT
IHDESLVIRLLPKMSSKPLTKLSLFPSATFKLLSFLKHSHGLMLFTGPTGSGKTTTLYSLIDYAKRHFKRNIITLEDPVE
SRSENILQVQVNEKAGMTYSAGLKAVLRHDPDMIILGEIRDAETAQIAVRAALTGHLVLSSMHAKNAKGAIYRLLELGVD
MTEIEQTLVAVSAQRLVDIVCPFCGDSCTLYCRLSRPVRRASVFELLYGKSLNLCIEEAKGRCGGIKTDTLKMLIRKGIA
LGYLPSKTYERWIGHED

Specific function: Required for uptake of DNA by competent cells [H]

COG id: COG2804

COG function: function code NU; Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP E family [H]

Homologues:

Organism=Escherichia coli, GI1789723, Length=263, Percent_Identity=46.3878326996198, Blast_Score=228, Evalue=3e-61,
Organism=Escherichia coli, GI1786296, Length=264, Percent_Identity=40.530303030303, Blast_Score=191, Evalue=5e-50,
Organism=Escherichia coli, GI87082188, Length=185, Percent_Identity=41.0810810810811, Blast_Score=122, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001482 [H]

Pfam domain/function: PF00437 GSPII_E [H]

EC number: NA

Molecular weight: Translated: 37729; Mature: 37729

Theoretical pI: Translated: 9.33; Mature: 9.33

Prosite motif: PS00662 T2SP_E

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKASDIHIVPGEKEAVVRFRIDDELFQKDGLTRNECSRLISHFKFLSSMDIGERRLPQSG
CCCCCEEEECCCCCEEEEEEECHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHCCCCCC
ALTLYINREPVHLRMSTLPTIHDESLVIRLLPKMSSKPLTKLSLFPSATFKLLSFLKHSH
CEEEEEECCCEEEEECCCCCCCCCCHHEEEHHCCCCCCCCEEEECCHHHHHHHHHHHHCC
GLMLFTGPTGSGKTTTLYSLIDYAKRHFKRNIITLEDPVESRSENILQVQVNEKAGMTYS
CEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCEEEEEECCCCCCCHH
AGLKAVLRHDPDMIILGEIRDAETAQIAVRAALTGHLVLSSMHAKNAKGAIYRLLELGVD
HHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
MTEIEQTLVAVSAQRLVDIVCPFCGDSCTLYCRLSRPVRRASVFELLYGKSLNLCIEEAK
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCHHHHHHHCC
GRCGGIKTDTLKMLIRKGIALGYLPSKTYERWIGHED
CCCCCCCHHHHHHHHHCCCEEECCCCHHHHHHCCCCC
>Mature Secondary Structure
MKASDIHIVPGEKEAVVRFRIDDELFQKDGLTRNECSRLISHFKFLSSMDIGERRLPQSG
CCCCCEEEECCCCCEEEEEEECHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHCCCCCC
ALTLYINREPVHLRMSTLPTIHDESLVIRLLPKMSSKPLTKLSLFPSATFKLLSFLKHSH
CEEEEEECCCEEEEECCCCCCCCCCHHEEEHHCCCCCCCCEEEECCHHHHHHHHHHHHCC
GLMLFTGPTGSGKTTTLYSLIDYAKRHFKRNIITLEDPVESRSENILQVQVNEKAGMTYS
CEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCEEEEEECCCCCCCHH
AGLKAVLRHDPDMIILGEIRDAETAQIAVRAALTGHLVLSSMHAKNAKGAIYRLLELGVD
HHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
MTEIEQTLVAVSAQRLVDIVCPFCGDSCTLYCRLSRPVRRASVFELLYGKSLNLCIEEAK
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCHHHHHHHCC
GRCGGIKTDTLKMLIRKGIALGYLPSKTYERWIGHED
CCCCCCCHHHHHHHHHCCCEEECCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2507524; 8969508; 9384377; 9422590; 9723928 [H]