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The map label for this gene is recQ [H]

Identifier: 52786183

GI number: 52786183

Start: 2378122

End: 2379618

Strand: Reverse

Name: recQ [H]

Synonym: BLi02441

Alternate gene names: 52786183

Gene position: 2379618-2378122 (Counterclockwise)

Preceding gene: 52786184

Following gene: 52786182

Centisome position: 56.35

GC content: 51.1

Gene sequence:

>1497_bases
ATGGATAAACTTCATCAGGCGCTCCGCAGGTATTTTGGTTATCATGCTTTTAAAAAAGGCCAGGAAACGATCATCAAAAG
CGTGCTGGAGGGACGGGACACGGTGGCGATGCTTCCGACAGGAGGCGGGAAATCGCTGTGCTATCAGCTCCCAGGGCTTT
TGTTAGACGGCACCGTCCTGATCGTCTCGCCGCTTTTGTCTTTAATGGAAGACCAGGTGCAGCAATTGAAGATGCGCGGA
GAGAAGAGAGCTGCCGCCTTGAACAGCGCTTTGACACACCAAGAAAAAAATGACGTATTAAACCGGCTTCACCGCCTCAA
ATATCTGTACATTTCACCAGAAGCGCTTCAGTCCGGCCAAATGCTGAAAAAGCTTCAATTGCTCAATGTCAGCCTTTTTG
TCGTTGATGAAGCCCACTGCATCTCACAATGGGGGCATGATTTCAGGCCTGATTATTCGAAGCTTGGAGACATCAAGGCG
CTCCTCGGTCATCCCGTCACTCTGGCGCTTACAGCAACGGCAACCGAAGCGACATTAAAGGACATTTCGGAAATCCTGGG
GCTTAAAGCCGCCAATTATTTGATTCATTCGGTCGACCGTCCGAACATTGCGCTTCATATTGAAAAGCTGAGGGATACTG
CTGAGAAGACGGAGCGGCTGACAGGGCTGGTTCAAAAGCTGCAAGGTCCTGGCCTTGTTTATTGCCCGACGAGAAAATGG
GCTGAAGAACTGGCTGACAAGCTCCGTAAAGAAGCAAACTTGAGAACGGGATTTTATCATGGCGGGATGGAGGCAAGCGA
CAGGATGCTGATCCAGCAGCAGTTTATCCGCAATCAGCTTGATGTGGTCTGCTGTACAAACGCCTTCGGTATGGGAGTGG
ACAAGCCGGATATCAGATATGTGATCCACTTTAGCCTCCCGCAGACGATTGAGGCGTATCTGCAGGAAATCGGACGTGCC
GGCAGGGATGGAAAGCGGAGCGTCAGCATTTTGCTGAAGGCTCCGGGAGACGAGGAAATCCAGGAGCAGCTGATTCAAAT
GGAAGCCCTCTCCCAAAGCGATATCGGCTTTTTATACGAAAAGCTTGCAGGAGTGAAAGATGAACGCTGCCGGCGGGAAG
CTCTGCAGCTGGCCGGTTTATCGGAAACGCAAGCCCGCCATTTTCTCCATCTTTATGAGAAGGTGCATCATCTGGGCGGC
GATGGCCGGGCGGTCATTCAGAGGGAGATGGACAGCCGCAGGCAGCTCAAATTGAAAAAAGCGGCGGGATTCGCCGCCGT
CACCGAAACAGAAGGGTGTTTCAGGGAAAGCTTGCTCGCTTATTTTAATGAACAAAAAAAGCCGCCGAAAACGGATGAAA
CAGCGTGCTGCACATCCTGCGGTTTAAGTCTTGAAGCATACGAAGTCAAAGGAGACCGTCCGTCTATGAACAAATTGACA
GCGTGGGAAGAAGAATTGGATACCATATTTGCCGCCAGCTGTGATCGTGTATGCTGA

Upstream 100 bases:

>100_bases
GCGAACCAAACCAATAAAATCAGACAAATTAAAGAGGGACTCGGCGGCCGATACAGTTATTTTAAAATCCGCCTGGCCCT
GTCGAAAACGGTGATCAGGA

Downstream 100 bases:

>100_bases
AAAAACAGTCGGAAATCATACGTCGCCTGTCAGACGGGGAAATGCTGAAACAGCTCTATTTTTCCCAGACGCTGATGCTT
TTTACCGCATTATTGATGGG

Product: RecQ

Products: NA

Alternate protein names: Recombination protein S [H]

Number of amino acids: Translated: 498; Mature: 498

Protein sequence:

>498_residues
MDKLHQALRRYFGYHAFKKGQETIIKSVLEGRDTVAMLPTGGGKSLCYQLPGLLLDGTVLIVSPLLSLMEDQVQQLKMRG
EKRAAALNSALTHQEKNDVLNRLHRLKYLYISPEALQSGQMLKKLQLLNVSLFVVDEAHCISQWGHDFRPDYSKLGDIKA
LLGHPVTLALTATATEATLKDISEILGLKAANYLIHSVDRPNIALHIEKLRDTAEKTERLTGLVQKLQGPGLVYCPTRKW
AEELADKLRKEANLRTGFYHGGMEASDRMLIQQQFIRNQLDVVCCTNAFGMGVDKPDIRYVIHFSLPQTIEAYLQEIGRA
GRDGKRSVSILLKAPGDEEIQEQLIQMEALSQSDIGFLYEKLAGVKDERCRREALQLAGLSETQARHFLHLYEKVHHLGG
DGRAVIQREMDSRRQLKLKKAAGFAAVTETEGCFRESLLAYFNEQKKPPKTDETACCTSCGLSLEAYEVKGDRPSMNKLT
AWEEELDTIFAASCDRVC

Sequences:

>Translated_498_residues
MDKLHQALRRYFGYHAFKKGQETIIKSVLEGRDTVAMLPTGGGKSLCYQLPGLLLDGTVLIVSPLLSLMEDQVQQLKMRG
EKRAAALNSALTHQEKNDVLNRLHRLKYLYISPEALQSGQMLKKLQLLNVSLFVVDEAHCISQWGHDFRPDYSKLGDIKA
LLGHPVTLALTATATEATLKDISEILGLKAANYLIHSVDRPNIALHIEKLRDTAEKTERLTGLVQKLQGPGLVYCPTRKW
AEELADKLRKEANLRTGFYHGGMEASDRMLIQQQFIRNQLDVVCCTNAFGMGVDKPDIRYVIHFSLPQTIEAYLQEIGRA
GRDGKRSVSILLKAPGDEEIQEQLIQMEALSQSDIGFLYEKLAGVKDERCRREALQLAGLSETQARHFLHLYEKVHHLGG
DGRAVIQREMDSRRQLKLKKAAGFAAVTETEGCFRESLLAYFNEQKKPPKTDETACCTSCGLSLEAYEVKGDRPSMNKLT
AWEEELDTIFAASCDRVC
>Mature_498_residues
MDKLHQALRRYFGYHAFKKGQETIIKSVLEGRDTVAMLPTGGGKSLCYQLPGLLLDGTVLIVSPLLSLMEDQVQQLKMRG
EKRAAALNSALTHQEKNDVLNRLHRLKYLYISPEALQSGQMLKKLQLLNVSLFVVDEAHCISQWGHDFRPDYSKLGDIKA
LLGHPVTLALTATATEATLKDISEILGLKAANYLIHSVDRPNIALHIEKLRDTAEKTERLTGLVQKLQGPGLVYCPTRKW
AEELADKLRKEANLRTGFYHGGMEASDRMLIQQQFIRNQLDVVCCTNAFGMGVDKPDIRYVIHFSLPQTIEAYLQEIGRA
GRDGKRSVSILLKAPGDEEIQEQLIQMEALSQSDIGFLYEKLAGVKDERCRREALQLAGLSETQARHFLHLYEKVHHLGG
DGRAVIQREMDSRRQLKLKKAAGFAAVTETEGCFRESLLAYFNEQKKPPKTDETACCTSCGLSLEAYEVKGDRPSMNKLT
AWEEELDTIFAASCDRVC

Specific function: Probable DNA helicase. Required in synaptic and/or post- synaptic stages of recombination. Probably has overlapping function with recQ (AC O34748). It probably acts to help generate ss-DNA from ds-DNA breaks [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI110735439, Length=381, Percent_Identity=40.6824146981627, Blast_Score=263, Evalue=3e-70,
Organism=Homo sapiens, GI169218196, Length=381, Percent_Identity=40.6824146981627, Blast_Score=263, Evalue=4e-70,
Organism=Homo sapiens, GI14591902, Length=383, Percent_Identity=35.509138381201, Blast_Score=240, Evalue=2e-63,
Organism=Homo sapiens, GI14591904, Length=383, Percent_Identity=35.509138381201, Blast_Score=240, Evalue=2e-63,
Organism=Homo sapiens, GI51242943, Length=367, Percent_Identity=38.6920980926431, Blast_Score=240, Evalue=2e-63,
Organism=Homo sapiens, GI51242947, Length=367, Percent_Identity=38.6920980926431, Blast_Score=240, Evalue=3e-63,
Organism=Homo sapiens, GI148612816, Length=367, Percent_Identity=38.6920980926431, Blast_Score=237, Evalue=2e-62,
Organism=Homo sapiens, GI4557365, Length=473, Percent_Identity=32.76955602537, Blast_Score=224, Evalue=2e-58,
Organism=Homo sapiens, GI284005309, Length=369, Percent_Identity=36.8563685636856, Blast_Score=212, Evalue=7e-55,
Organism=Homo sapiens, GI45446747, Length=351, Percent_Identity=24.5014245014245, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI45446743, Length=351, Percent_Identity=24.5014245014245, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI262118318, Length=423, Percent_Identity=25.0591016548463, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI7661920, Length=343, Percent_Identity=23.6151603498542, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI222352149, Length=353, Percent_Identity=24.3626062322946, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI216548263, Length=423, Percent_Identity=25.0591016548463, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI262231852, Length=423, Percent_Identity=25.0591016548463, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI13518015, Length=423, Percent_Identity=25.0591016548463, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI188035877, Length=338, Percent_Identity=23.0769230769231, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI4758138, Length=349, Percent_Identity=25.214899713467, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI13514831, Length=373, Percent_Identity=23.5924932975871, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI148613856, Length=353, Percent_Identity=23.5127478753541, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI38201710, Length=353, Percent_Identity=23.5127478753541, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI48994977, Length=383, Percent_Identity=42.5587467362924, Blast_Score=291, Evalue=8e-80,
Organism=Escherichia coli, GI1788930, Length=329, Percent_Identity=24.6200607902736, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI32564293, Length=346, Percent_Identity=39.8843930635838, Blast_Score=258, Evalue=7e-69,
Organism=Caenorhabditis elegans, GI25145561, Length=346, Percent_Identity=40.4624277456647, Blast_Score=249, Evalue=3e-66,
Organism=Caenorhabditis elegans, GI71987997, Length=405, Percent_Identity=38.0246913580247, Blast_Score=246, Evalue=1e-65,
Organism=Caenorhabditis elegans, GI71987993, Length=405, Percent_Identity=38.0246913580247, Blast_Score=246, Evalue=2e-65,
Organism=Caenorhabditis elegans, GI17552866, Length=320, Percent_Identity=37.5, Blast_Score=205, Evalue=4e-53,
Organism=Caenorhabditis elegans, GI71995724, Length=345, Percent_Identity=24.6376811594203, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17507121, Length=345, Percent_Identity=24.3478260869565, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17507945, Length=342, Percent_Identity=24.2690058479532, Blast_Score=69, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6323844, Length=360, Percent_Identity=35.8333333333333, Blast_Score=236, Evalue=6e-63,
Organism=Saccharomyces cerevisiae, GI6320224, Length=341, Percent_Identity=24.3401759530792, Blast_Score=78, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6320449, Length=351, Percent_Identity=23.9316239316239, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6324217, Length=330, Percent_Identity=24.5454545454545, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6325138, Length=239, Percent_Identity=27.1966527196653, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320400, Length=377, Percent_Identity=20.6896551724138, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24646066, Length=343, Percent_Identity=39.067055393586, Blast_Score=248, Evalue=6e-66,
Organism=Drosophila melanogaster, GI24664226, Length=350, Percent_Identity=37.7142857142857, Blast_Score=229, Evalue=3e-60,
Organism=Drosophila melanogaster, GI62472181, Length=372, Percent_Identity=36.8279569892473, Blast_Score=228, Evalue=9e-60,
Organism=Drosophila melanogaster, GI24664230, Length=372, Percent_Identity=36.8279569892473, Blast_Score=228, Evalue=9e-60,
Organism=Drosophila melanogaster, GI21358123, Length=353, Percent_Identity=36.8271954674221, Blast_Score=198, Evalue=8e-51,
Organism=Drosophila melanogaster, GI21355075, Length=347, Percent_Identity=22.7665706051873, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24645031, Length=337, Percent_Identity=23.7388724035608, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24644479, Length=386, Percent_Identity=23.0569948186528, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI281361218, Length=386, Percent_Identity=23.0569948186528, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24644481, Length=386, Percent_Identity=23.0569948186528, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24644483, Length=386, Percent_Identity=23.0569948186528, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24644487, Length=386, Percent_Identity=23.0569948186528, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI45551833, Length=386, Percent_Identity=23.0569948186528, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24644485, Length=386, Percent_Identity=23.0569948186528, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR002464
- InterPro:   IPR004589
- InterPro:   IPR001650
- InterPro:   IPR014021 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 55885; Mature: 55885

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: PS00690 DEAH_ATP_HELICASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKLHQALRRYFGYHAFKKGQETIIKSVLEGRDTVAMLPTGGGKSLCYQLPGLLLDGTVL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHCCCHHHCCHHH
IVSPLLSLMEDQVQQLKMRGEKRAAALNSALTHQEKNDVLNRLHRLKYLYISPEALQSGQ
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECHHHHHHHH
MLKKLQLLNVSLFVVDEAHCISQWGHDFRPDYSKLGDIKALLGHPVTLALTATATEATLK
HHHHHHHHCEEEEEEEHHHHHHHCCCCCCCCHHHHHHHHHHHCCCEEEEEEECHHHHHHH
DISEILGLKAANYLIHSVDRPNIALHIEKLRDTAEKTERLTGLVQKLQGPGLVYCPTRKW
HHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHH
AEELADKLRKEANLRTGFYHGGMEASDRMLIQQQFIRNQLDVVCCTNAFGMGVDKPDIRY
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEE
VIHFSLPQTIEAYLQEIGRAGRDGKRSVSILLKAPGDEEIQEQLIQMEALSQSDIGFLYE
EEEECCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHH
KLAGVKDERCRREALQLAGLSETQARHFLHLYEKVHHLGGDGRAVIQREMDSRRQLKLKK
HHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
AAGFAAVTETEGCFRESLLAYFNEQKKPPKTDETACCTSCGLSLEAYEVKGDRPSMNKLT
HCCCEEEECCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCEEEEEECCCCCCCHHHH
AWEEELDTIFAASCDRVC
HHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDKLHQALRRYFGYHAFKKGQETIIKSVLEGRDTVAMLPTGGGKSLCYQLPGLLLDGTVL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHCCCHHHCCHHH
IVSPLLSLMEDQVQQLKMRGEKRAAALNSALTHQEKNDVLNRLHRLKYLYISPEALQSGQ
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECHHHHHHHH
MLKKLQLLNVSLFVVDEAHCISQWGHDFRPDYSKLGDIKALLGHPVTLALTATATEATLK
HHHHHHHHCEEEEEEEHHHHHHHCCCCCCCCHHHHHHHHHHHCCCEEEEEEECHHHHHHH
DISEILGLKAANYLIHSVDRPNIALHIEKLRDTAEKTERLTGLVQKLQGPGLVYCPTRKW
HHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHH
AEELADKLRKEANLRTGFYHGGMEASDRMLIQQQFIRNQLDVVCCTNAFGMGVDKPDIRY
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEE
VIHFSLPQTIEAYLQEIGRAGRDGKRSVSILLKAPGDEEIQEQLIQMEALSQSDIGFLYE
EEEECCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHH
KLAGVKDERCRREALQLAGLSETQARHFLHLYEKVHHLGGDGRAVIQREMDSRRQLKLKK
HHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
AAGFAAVTETEGCFRESLLAYFNEQKKPPKTDETACCTSCGLSLEAYEVKGDRPSMNKLT
HCCCEEEECCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCEEEEEECCCCCCCHHHH
AWEEELDTIFAASCDRVC
HHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377; 9642195 [H]