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The map label for this gene is hepT [H]

Identifier: 52786153

GI number: 52786153

Start: 2352553

End: 2353515

Strand: Reverse

Name: hepT [H]

Synonym: BLi02409

Alternate gene names: 52786153

Gene position: 2353515-2352553 (Counterclockwise)

Preceding gene: 52786154

Following gene: 52786152

Centisome position: 55.74

GC content: 45.38

Gene sequence:

>963_bases
ATGAAATTGACAACGTTTTATTCTTTTTTGAATGACGATATTGAATTAATAGAAAAAGAGCTTGAAAAGACCGTGCACTC
CGACTATCCATTGCTCAGTGAAGCGAGCCTGCATTTGCTGCAGGCCGGAGGCAAGAGGATTCGTCCCGTGTTTGTCCTGC
TTTCCGGCATGTTCGGCGAATACGACATCAGCAAAATTAAAAATGTTGCCGTTTCGTTGGAATTGATACATATGGCTTCG
CTCGTACACGACGATGTCATCGATGATGCGGAGCTGAGAAGAGGACAGCCGACAATCAAAGCGAAGTGGGATAACCGGAT
TGCAATGTATACAGGTGATTATTTGTTCGCTCGCTCACTTGAAGCGATGACAAAAATAAACGAACCGAAAGCCCATGAAA
TCTTGTCCAAGGCGATTGTCGAAGTCTGTCTTGGAGAAATTGAACAAATTAAAGATAAATATAATATGGAGCAAAATCTC
AGAACCTATTTGAGAAGAATCAGGCGCAAGACAGCACTTCTAATCGCGTCGAGCTGCCAGCTTGGAGCCATTGCTGCTGG
TGCGGGTGAAAACATTCATAAAACGTTGTACTGGTTTGGCTATTATGTCGGCATGTCCTATCAAATTATTGATGACATCC
TCGATTTCACCTCAAGCGAAAAAGAGCTTGGCAAGCCTGTGGGCAGCGATCTGCTTCAGGGGAATGTCACGCTTCCCGTA
TTATATGCACGGAAATCGCCTGAGCTAAAAGCGCGCCTGATGCTGGTCAACAGTGAAACCACTCCAGAACAGATCAAGCC
AGTGATCGAAGAGCTGAAGAAAACGGATGCCATTGAACAATCGTTCAGGGTCAGTGAAATGTATTTAAACAAGGCTTTCG
AACTGCTTGAAACGCTCCCGAAAAACCGGGCGCGGACGGCACTGGGCCAAATTGCGAAATACATCGGCAAGCGAAAGTTC
TAA

Upstream 100 bases:

>100_bases
GATTAAAAAATGTTCAATATCATCCGTTCACAGGCGGCGTAGCGGCAACACATGTCGGCTGGAAGCGATGATGACTACAG
AAATACTCGGGTGAATCGAT

Downstream 100 bases:

>100_bases
AAAACGTCAAATGAGTCGAAAGTATGAATATTCTCCACCCTTTATTGATTAATTGTTTGAAAAATGCTATATTTCTGTTG
TAGTGTTGAAAGCCTATACA

Product: heptaprenyl diphosphate synthase subunit HepT

Products: NA

Alternate protein names: HEPPP synthase subunit 2; Spore germination protein C3 [H]

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MKLTTFYSFLNDDIELIEKELEKTVHSDYPLLSEASLHLLQAGGKRIRPVFVLLSGMFGEYDISKIKNVAVSLELIHMAS
LVHDDVIDDAELRRGQPTIKAKWDNRIAMYTGDYLFARSLEAMTKINEPKAHEILSKAIVEVCLGEIEQIKDKYNMEQNL
RTYLRRIRRKTALLIASSCQLGAIAAGAGENIHKTLYWFGYYVGMSYQIIDDILDFTSSEKELGKPVGSDLLQGNVTLPV
LYARKSPELKARLMLVNSETTPEQIKPVIEELKKTDAIEQSFRVSEMYLNKAFELLETLPKNRARTALGQIAKYIGKRKF

Sequences:

>Translated_320_residues
MKLTTFYSFLNDDIELIEKELEKTVHSDYPLLSEASLHLLQAGGKRIRPVFVLLSGMFGEYDISKIKNVAVSLELIHMAS
LVHDDVIDDAELRRGQPTIKAKWDNRIAMYTGDYLFARSLEAMTKINEPKAHEILSKAIVEVCLGEIEQIKDKYNMEQNL
RTYLRRIRRKTALLIASSCQLGAIAAGAGENIHKTLYWFGYYVGMSYQIIDDILDFTSSEKELGKPVGSDLLQGNVTLPV
LYARKSPELKARLMLVNSETTPEQIKPVIEELKKTDAIEQSFRVSEMYLNKAFELLETLPKNRARTALGQIAKYIGKRKF
>Mature_320_residues
MKLTTFYSFLNDDIELIEKELEKTVHSDYPLLSEASLHLLQAGGKRIRPVFVLLSGMFGEYDISKIKNVAVSLELIHMAS
LVHDDVIDDAELRRGQPTIKAKWDNRIAMYTGDYLFARSLEAMTKINEPKAHEILSKAIVEVCLGEIEQIKDKYNMEQNL
RTYLRRIRRKTALLIASSCQLGAIAAGAGENIHKTLYWFGYYVGMSYQIIDDILDFTSSEKELGKPVGSDLLQGNVTLPV
LYARKSPELKARLMLVNSETTPEQIKPVIEELKKTDAIEQSFRVSEMYLNKAFELLETLPKNRARTALGQIAKYIGKRKF

Specific function: Supplies heptaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinone menaquinone-7 (MQ-7) [H]

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI50659086, Length=295, Percent_Identity=31.864406779661, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI169808399, Length=339, Percent_Identity=25.6637168141593, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI4758430, Length=228, Percent_Identity=25.4385964912281, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI83700220, Length=228, Percent_Identity=25.4385964912281, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1789578, Length=316, Percent_Identity=31.0126582278481, Blast_Score=171, Evalue=6e-44,
Organism=Escherichia coli, GI1786623, Length=251, Percent_Identity=29.4820717131474, Blast_Score=87, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17505681, Length=315, Percent_Identity=32.0634920634921, Blast_Score=159, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6319475, Length=303, Percent_Identity=30.3630363036304, Blast_Score=144, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6325188, Length=221, Percent_Identity=24.4343891402715, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24651612, Length=323, Percent_Identity=29.1021671826625, Blast_Score=160, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014119
- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.30 [H]

Molecular weight: Translated: 36398; Mature: 36398

Theoretical pI: Translated: 8.17; Mature: 8.17

Prosite motif: PS00723 POLYPRENYL_SYNTHET_1 ; PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTTFYSFLNDDIELIEKELEKTVHSDYPLLSEASLHLLQAGGKRIRPVFVLLSGMFGE
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
YDISKIKNVAVSLELIHMASLVHDDVIDDAELRRGQPTIKAKWDNRIAMYTGDYLFARSL
CHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCEEEECCCEEEEEECCHHHHHHH
EAMTKINEPKAHEILSKAIVEVCLGEIEQIKDKYNMEQNLRTYLRRIRRKTALLIASSCQ
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCC
LGAIAAGAGENIHKTLYWFGYYVGMSYQIIDDILDFTSSEKELGKPVGSDLLQGNVTLPV
CCEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHCCCHHHHHHCCCCCEEE
LYARKSPELKARLMLVNSETTPEQIKPVIEELKKTDAIEQSFRVSEMYLNKAFELLETLP
EEECCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KNRARTALGQIAKYIGKRKF
CHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKLTTFYSFLNDDIELIEKELEKTVHSDYPLLSEASLHLLQAGGKRIRPVFVLLSGMFGE
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
YDISKIKNVAVSLELIHMASLVHDDVIDDAELRRGQPTIKAKWDNRIAMYTGDYLFARSL
CHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCEEEECCCEEEEEECCHHHHHHH
EAMTKINEPKAHEILSKAIVEVCLGEIEQIKDKYNMEQNLRTYLRRIRRKTALLIASSCQ
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCC
LGAIAAGAGENIHKTLYWFGYYVGMSYQIIDDILDFTSSEKELGKPVGSDLLQGNVTLPV
CCEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHCCCHHHHHHCCCCCEEE
LYARKSPELKARLMLVNSETTPEQIKPVIEELKKTDAIEQSFRVSEMYLNKAFELLETLP
EEECCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KNRARTALGQIAKYIGKRKF
CHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 2121900; 9720033 [H]