Click here to switch to the map view.

The map label for this gene is recU

Identifier: 52786110

GI number: 52786110

Start: 2311483

End: 2312079

Strand: Direct

Name: recU

Synonym: BLi02366

Alternate gene names: 52786110

Gene position: 2311483-2312079 (Clockwise)

Preceding gene: 52786106

Following gene: 52786111

Centisome position: 54.74

GC content: 42.04

Gene sequence:

>597_bases
GTGATTCGTTACCCGAACGGCAAATCCTATCAGCCGAAAACAGCTGCCTCATCCTTGCAAAAGAAGCCGTCGTATTCCAA
TCGCGGCATGACCCTCGAAGATGACCTGAATGAAACGAATATGTATTATCAATCTCATTCGATTGCGGTCATCCATAAAA
AACCGACACCTGTACAGATTGTCCAGGTCGATTATCCGAAGCGAAGCGCTGCGGTTATCAAAGAAGCATATTTCAAGCAG
TCGTCAACTACTGATTATAATGGGGTTTATAAAGGCCGCTACATCGATTTTGAAGCGAAAGAAACAAAGAGCCGAACCTC
GTTCCCGCTTCAGAATTTCCACGATCATCAGATCGAGCATATGAAGCAGGTTGTGGCGCAAGACGGCATTTGTTTTGTTA
TCATATCCGCTTTTGAAGAAATTTATTTTTTGGAAGCAGAAAAATTATTTTATTTCTGGGAGCGGAAAAAGCAAAACGGC
AGAAAATCGATCCGAAAAGACGAGCTTCAGGAAGCCGCTCACCCCATTTCACTTGGATACTCGCCAAGAATTGATTATAT
TAAGATTATTGATCAGTTGTATTTTTCGCCATCATAA

Upstream 100 bases:

>100_bases
TCTTGAATGCGGCTCGTCAGCTCCGCCGCGGAAAAAGTGTTGTGCAAGATCAGCCACTTCCGTTAGTATCCAGATTTTTT
GTAAAAGGAGGATGAAGAAA

Downstream 100 bases:

>100_bases
ATTATGATTTTAAAGTCATGTGAGCGGAAAGGTTTAACTACGAAAGGTTGAGATGTTATGTCAGATCAATTTAACAGCCG
CCAGGAACGGCGAAAAGCCC

Product: Holliday junction-specific endonuclease

Products: NA

Alternate protein names: Recombination protein U homolog

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MIRYPNGKSYQPKTAASSLQKKPSYSNRGMTLEDDLNETNMYYQSHSIAVIHKKPTPVQIVQVDYPKRSAAVIKEAYFKQ
SSTTDYNGVYKGRYIDFEAKETKSRTSFPLQNFHDHQIEHMKQVVAQDGICFVIISAFEEIYFLEAEKLFYFWERKKQNG
RKSIRKDELQEAAHPISLGYSPRIDYIKIIDQLYFSPS

Sequences:

>Translated_198_residues
MIRYPNGKSYQPKTAASSLQKKPSYSNRGMTLEDDLNETNMYYQSHSIAVIHKKPTPVQIVQVDYPKRSAAVIKEAYFKQ
SSTTDYNGVYKGRYIDFEAKETKSRTSFPLQNFHDHQIEHMKQVVAQDGICFVIISAFEEIYFLEAEKLFYFWERKKQNG
RKSIRKDELQEAAHPISLGYSPRIDYIKIIDQLYFSPS
>Mature_198_residues
MIRYPNGKSYQPKTAASSLQKKPSYSNRGMTLEDDLNETNMYYQSHSIAVIHKKPTPVQIVQVDYPKRSAAVIKEAYFKQ
SSTTDYNGVYKGRYIDFEAKETKSRTSFPLQNFHDHQIEHMKQVVAQDGICFVIISAFEEIYFLEAEKLFYFWERKKQNG
RKSIRKDELQEAAHPISLGYSPRIDYIKIIDQLYFSPS

Specific function: Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair

COG id: COG3331

COG function: function code R; Penicillin-binding protein-related factor A, putative recombinase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recU family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RECU_BACLD (Q65I68)

Other databases:

- EMBL:   CP000002
- EMBL:   AE017333
- RefSeq:   YP_079530.1
- RefSeq:   YP_091939.1
- HSSP:   P39792
- ProteinModelPortal:   Q65I68
- SMR:   Q65I68
- STRING:   Q65I68
- EnsemblBacteria:   EBBACT00000056982
- EnsemblBacteria:   EBBACT00000058834
- GeneID:   3029469
- GeneID:   3100150
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi02366
- KEGG:   bli:BL02731
- NMPDR:   fig|279010.5.peg.217
- eggNOG:   COG3331
- GeneTree:   EBGT00050000001230
- HOGENOM:   HBG571967
- OMA:   GHYIDFE
- ProtClustDB:   PRK02234
- BioCyc:   BLIC279010-1:BLI02366-MONOMER
- BioCyc:   BLIC279010:BL02731-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00130
- InterPro:   IPR004612
- InterPro:   IPR011335
- PIRSF:   PIRSF037785
- TIGRFAMs:   TIGR00648

Pfam domain/function: PF03838 RecU; SSF52980 Restrict_endonuc_II-like_core

EC number: NA

Molecular weight: Translated: 23143; Mature: 23143

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRYPNGKSYQPKTAASSLQKKPSYSNRGMTLEDDLNETNMYYQSHSIAVIHKKPTPVQI
CCCCCCCCCCCCHHHHHHHHCCCCCCCCCCEECCCCCCCCEEEECCCEEEEECCCCCEEE
VQVDYPKRSAAVIKEAYFKQSSTTDYNGVYKGRYIDFEAKETKSRTSFPLQNFHDHQIEH
EEECCCCHHHHHHHHHHHCCCCCCCCCCEECCEEEECCCHHCCCCCCCCCCCCCHHHHHH
MKQVVAQDGICFVIISAFEEIYFLEAEKLFYFWERKKQNGRKSIRKDELQEAAHPISLGY
HHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SPRIDYIKIIDQLYFSPS
CCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIRYPNGKSYQPKTAASSLQKKPSYSNRGMTLEDDLNETNMYYQSHSIAVIHKKPTPVQI
CCCCCCCCCCCCHHHHHHHHCCCCCCCCCCEECCCCCCCCEEEECCCEEEEECCCCCEEE
VQVDYPKRSAAVIKEAYFKQSSTTDYNGVYKGRYIDFEAKETKSRTSFPLQNFHDHQIEH
EEECCCCHHHHHHHHHHHCCCCCCCCCCEECCEEEECCCHHCCCCCCCCCCCCCHHHHHH
MKQVVAQDGICFVIISAFEEIYFLEAEKLFYFWERKKQNGRKSIRKDELQEAAHPISLGY
HHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SPRIDYIKIIDQLYFSPS
CCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA