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The map label for this gene is bsaA [H]

Identifier: 52786071

GI number: 52786071

Start: 2277135

End: 2277614

Strand: Reverse

Name: bsaA [H]

Synonym: BLi02327

Alternate gene names: 52786071

Gene position: 2277614-2277135 (Counterclockwise)

Preceding gene: 52786072

Following gene: 52786070

Centisome position: 53.94

GC content: 47.29

Gene sequence:

>480_bases
ATGTCCATTTACGATATCAGCGTCAAGACGATTAAAGGCGAGGACACGACACTGCGGCCGTATAAAGGCAAAGTGCTGCT
CATCGTCAACACCGCCTCGAAGTGCGGATTTACACCTCAATATCAGCAGCTTCAAGACTTGTATGAAACATATAAAGACC
GGGGGCTTGAGATTCTCGGCTTTCCCAGCAACCAATTCATGAATCAGGAGCCGGGCGATGAAAAAAGCATTGAAGAATTT
TGCAGCGTCAATTACGGTGTCACGTTTCCGATGTTTTCGAAGGTGAATGTAAAAGGGGATCAAATCCACCCGCTGTTCCG
CCACTTGACGAACAAGGCGAAGGGCATGCTTGGAACAAAAGCGGTCAAATGGAATTTCACAAAATTTCTCGTCGATCAAA
CCGGAGAAAACGTTGTGCGCTTTTCACCGCAAACCAATCCAAAGGAGATGGAGGAGACCATTCAGAAATGGCTGGGCTGA

Upstream 100 bases:

>100_bases
TTTAACAATGCCGGGGCTGCCGAAACACCCTGCCGCGCTTAAGATGGATGTCGACGAAAGCGGCAGAGCCAAAGGTTTAT
TCTAAAAAGGAGGGACCGTC

Downstream 100 bases:

>100_bases
ATCAGGAACAAACAGAACAGATCCGCTTGATGTCCGAATGGGTAAAAGAGAAGCTTTCTGCCGAAGGCACAGGTCATGAC
TGGCTGCATACCGAAAGGGT

Product: BsaA

Products: glutathione disulfide; H2O

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 158

Protein sequence:

>159_residues
MSIYDISVKTIKGEDTTLRPYKGKVLLIVNTASKCGFTPQYQQLQDLYETYKDRGLEILGFPSNQFMNQEPGDEKSIEEF
CSVNYGVTFPMFSKVNVKGDQIHPLFRHLTNKAKGMLGTKAVKWNFTKFLVDQTGENVVRFSPQTNPKEMEETIQKWLG

Sequences:

>Translated_159_residues
MSIYDISVKTIKGEDTTLRPYKGKVLLIVNTASKCGFTPQYQQLQDLYETYKDRGLEILGFPSNQFMNQEPGDEKSIEEF
CSVNYGVTFPMFSKVNVKGDQIHPLFRHLTNKAKGMLGTKAVKWNFTKFLVDQTGENVVRFSPQTNPKEMEETIQKWLG
>Mature_158_residues
SIYDISVKTIKGEDTTLRPYKGKVLLIVNTASKCGFTPQYQQLQDLYETYKDRGLEILGFPSNQFMNQEPGDEKSIEEFC
SVNYGVTFPMFSKVNVKGDQIHPLFRHLTNKAKGMLGTKAVKWNFTKFLVDQTGENVVRFSPQTNPKEMEETIQKWLG

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI75709200, Length=156, Percent_Identity=44.8717948717949, Blast_Score=129, Evalue=1e-30,
Organism=Homo sapiens, GI90903240, Length=156, Percent_Identity=44.8717948717949, Blast_Score=128, Evalue=2e-30,
Organism=Homo sapiens, GI90903238, Length=131, Percent_Identity=47.3282442748092, Blast_Score=113, Evalue=7e-26,
Organism=Homo sapiens, GI15618997, Length=152, Percent_Identity=40.1315789473684, Blast_Score=112, Evalue=1e-25,
Organism=Homo sapiens, GI192455698, Length=150, Percent_Identity=40.6666666666667, Blast_Score=109, Evalue=9e-25,
Organism=Homo sapiens, GI4557629, Length=177, Percent_Identity=34.4632768361582, Blast_Score=88, Evalue=3e-18,
Organism=Homo sapiens, GI6006001, Length=177, Percent_Identity=32.7683615819209, Blast_Score=79, Evalue=1e-15,
Organism=Homo sapiens, GI41406084, Length=184, Percent_Identity=33.1521739130435, Blast_Score=76, Evalue=1e-14,
Organism=Homo sapiens, GI33186887, Length=177, Percent_Identity=29.9435028248588, Blast_Score=75, Evalue=3e-14,
Organism=Homo sapiens, GI32967607, Length=181, Percent_Identity=29.8342541436464, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1788003, Length=167, Percent_Identity=44.311377245509, Blast_Score=151, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17506887, Length=159, Percent_Identity=47.7987421383648, Blast_Score=153, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI17535473, Length=158, Percent_Identity=46.2025316455696, Blast_Score=143, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI193210707, Length=162, Percent_Identity=42.5925925925926, Blast_Score=120, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI71993584, Length=158, Percent_Identity=37.9746835443038, Blast_Score=117, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17550320, Length=163, Percent_Identity=31.9018404907975, Blast_Score=97, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI193209493, Length=163, Percent_Identity=31.9018404907975, Blast_Score=94, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI71999642, Length=76, Percent_Identity=40.7894736842105, Blast_Score=72, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71993573, Length=95, Percent_Identity=36.8421052631579, Blast_Score=69, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6319721, Length=157, Percent_Identity=51.5923566878981, Blast_Score=176, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6322228, Length=156, Percent_Identity=48.7179487179487, Blast_Score=165, Evalue=3e-42,
Organism=Saccharomyces cerevisiae, GI6322826, Length=155, Percent_Identity=44.5161290322581, Blast_Score=137, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24656772, Length=159, Percent_Identity=44.6540880503145, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24656767, Length=159, Percent_Identity=44.6540880503145, Blast_Score=134, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24656777, Length=159, Percent_Identity=44.6540880503145, Blast_Score=134, Evalue=2e-32,
Organism=Drosophila melanogaster, GI85726443, Length=161, Percent_Identity=37.2670807453416, Blast_Score=103, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: 1.11.1.9

Molecular weight: Translated: 18227; Mature: 18096

Theoretical pI: Translated: 8.65; Mature: 8.65

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1 ; PS00763 GLUTATHIONE_PEROXID_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIYDISVKTIKGEDTTLRPYKGKVLLIVNTASKCGFTPQYQQLQDLYETYKDRGLEILG
CCEEEEEEEEECCCCCEECCCCCEEEEEEECCHHCCCCCCHHHHHHHHHHHHHCCCEEEE
FPSNQFMNQEPGDEKSIEEFCSVNYGVTFPMFSKVNVKGDQIHPLFRHLTNKAKGMLGTK
CCCHHCCCCCCCCHHHHHHHHCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHCCCCCCE
AVKWNFTKFLVDQTGENVVRFSPQTNPKEMEETIQKWLG
EEEECHHHHEECCCCCCEEEECCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SIYDISVKTIKGEDTTLRPYKGKVLLIVNTASKCGFTPQYQQLQDLYETYKDRGLEILG
CEEEEEEEEECCCCCEECCCCCEEEEEEECCHHCCCCCCHHHHHHHHHHHHHCCCEEEE
FPSNQFMNQEPGDEKSIEEFCSVNYGVTFPMFSKVNVKGDQIHPLFRHLTNKAKGMLGTK
CCCHHCCCCCCCCHHHHHHHHCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHCCCCCCE
AVKWNFTKFLVDQTGENVVRFSPQTNPKEMEETIQKWLG
EEEECHHHHEECCCCCCEEEECCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: glutathione; H2O2

Specific reaction: 2 glutathione + H2O2 = glutathione disulfide + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]