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The map label for this gene is tlpB [H]

Identifier: 52785932

GI number: 52785932

Start: 2146386

End: 2148371

Strand: Direct

Name: tlpB [H]

Synonym: BLi02183

Alternate gene names: 52785932

Gene position: 2146386-2148371 (Clockwise)

Preceding gene: 52785925

Following gene: 52785934

Centisome position: 50.83

GC content: 46.73

Gene sequence:

>1986_bases
ATGAAAAAAATATTGGAATGGTTCAAGCATCCATCTCTTTCAAAAAGATTAGCGGTCTCATTTTTATTGATTTTAACGCT
CCCTGTTTTAATCCTTTCAGGTGTTTCCTATTATACGGCAGGCGGGTCGATTGAAGATGAAATCATGAGAAGCGCAAGAA
ACAGCGTGGATCAATTAAACGAAATGATCGATCAAAACATTGAGAAAAAAGCGGATGCTGTTACATATTTCAGTGAAGAG
ATCAAAGAAAAAACATACAAGGAAAAAGGCCAGACTTCGTTAAGACAAAAGTTTGAACAATACGCCAGGCAAAACAAAGA
TGTAGAAGCCGTTTTCACAGGCTCTGAAGACGGTGTATACGTGCAGCACCCTTATACGAAAATGCCTGACGGCTATAATC
CGGCGGAAAGGCCCTGGTTTAAAGAAGCGGTTGAGAAAAAAGGCGAAATTATCGTTACCGATCCATACACATCTGCCGCT
ACCGGCAACACGGTCATTACCATCGCCAAACAAAATAAAGACGGGTCGGGCGTCGCTGCGCTCAGCTTGAATATCGACGA
GCTGATTAAAGCGACAAACGATATCAAAGTCGGAAAAGACGGCTTTGCTTTTATCTCAAGTGCGTCCAAAAAATATATCG
CCCACCCGACGATTAAAGCCGGAACTGAAGGTGAAGGCGGCTGGGTTGATCAAGTTTACGGCAAAGGAAAAGGCGAATTC
AAGTATACTTTTGAAGGAAAAGCCAAGCAAATGGCTTTTACGACAAACAAACTGACAGGCTGGAAAATCGCCGGGACGAT
GTTTTCCGATGAGATAACAAACGCAACAAAGCCCGTCCTTTATATGGCTCTCATCGTCTTTTCAGGGGCTTTGGTGCTTG
GCGGAGTTCTCATTTTCTTTATTGTCCGCGCGATTAGCAAACCATTGAATCAGCTCGTTCTATCTGCAAAGAACATCAGC
AGCGGCGATTTGACACAGCAAATCGAAGTGCGTTCAAATGACGAATTCGGGCAGCTCGGCAAAAGCTTCAATGACATGGC
GGAATCGCTCCGCACACTGATCGGCACCATTCAGGAATCGGTTGAGAATGTCGCCTCCTCTTCTGAGCAGCTGACAGCAA
GCGCAGAACAGACGAGCCAAGCGACAGAACATATTACATCTGCGATCGAACAGTTCTCTAACGGGGCTGAAAGCCAGAAT
GAAAAAGTCGAAACGAGCTCGCAGCAGCTCAGCCAGATGAATGATCATCTGAGCGAAATGACCGAAGTGTCGGAATCAAT
CACCGAAGCATCGATCAAATCGACAGAAATCGCCGAAACCGGAGGAGAACTCGTTCAGAAAACGGTCGGCCAGATGAGTT
CAATCGACCAATCTGTCAAACAAGCTGAGAGCGTCGTCAAAGGCCTCGAAGGCAAATCGAAGGATATCACATCAATTCTC
AGGGTCATTAACGGAATTGCCGATCAAACGAATCTATTGGCATTGAACGCCGCGATTGAAGCAGCCCGCGCCGGCGAGTC
AGGCAGAGGATTTTCCGTCGTCGCCGAAGAAGTTCGAAAGCTTGCCGCGCAGTCAGCGGACTCGGCAAAAGAAATCGAAG
CGTTGATTCAGGAAATCGTCAAAGAAATCGAACATTCTCTCAGCATGTTTCAATCGGTCAACCATGAAGTGCAGTCCGGA
CTTAAAATTACCGAGAAAACAGAGTCGAGCTTTCACGAAATCAGCGGCATGACGAATGAGATCGCAGGCAAGCTGCAAAC
GCTCAATGCGGCGGTCGAACAGTTGTCGAATGGCTCGCAGGAAGTCTCCGGTGCCGTTCAGGAAATCGCCGATGTATCAA
GGGAAAGTACAGCTGGAATCCAGGACATTGCTGCATCAGCGGAAGAACAGCTGGCTTCAATGGAAGAAATCAGTACATCC
TCTGCCACGCTTGAGCAGATGGCGGAAGATCTGCGAGAATTGACGAAAAAATTCAAGGTGAAATAA

Upstream 100 bases:

>100_bases
TTGAGGATTTTGTTTTGAAGCCAAAATTTTTAAATTTAATGCAAAAGTGTGAAAATTGTCCGATATTATTCTCGTAACCT
AGAAAAAGGAGTTTTGGCTA

Downstream 100 bases:

>100_bases
AAAAGAGAGGCTTCCTTCATTTAGAGGGAGCCTCTCTTTTATGTATCAGCTGATCTTCGTTCCATTGGGCGCTTCTTGAT
CAGGGGCCAGCAATATAACA

Product: TlpB

Products: NA

Alternate protein names: H3 [H]

Number of amino acids: Translated: 661; Mature: 661

Protein sequence:

>661_residues
MKKILEWFKHPSLSKRLAVSFLLILTLPVLILSGVSYYTAGGSIEDEIMRSARNSVDQLNEMIDQNIEKKADAVTYFSEE
IKEKTYKEKGQTSLRQKFEQYARQNKDVEAVFTGSEDGVYVQHPYTKMPDGYNPAERPWFKEAVEKKGEIIVTDPYTSAA
TGNTVITIAKQNKDGSGVAALSLNIDELIKATNDIKVGKDGFAFISSASKKYIAHPTIKAGTEGEGGWVDQVYGKGKGEF
KYTFEGKAKQMAFTTNKLTGWKIAGTMFSDEITNATKPVLYMALIVFSGALVLGGVLIFFIVRAISKPLNQLVLSAKNIS
SGDLTQQIEVRSNDEFGQLGKSFNDMAESLRTLIGTIQESVENVASSSEQLTASAEQTSQATEHITSAIEQFSNGAESQN
EKVETSSQQLSQMNDHLSEMTEVSESITEASIKSTEIAETGGELVQKTVGQMSSIDQSVKQAESVVKGLEGKSKDITSIL
RVINGIADQTNLLALNAAIEAARAGESGRGFSVVAEEVRKLAAQSADSAKEIEALIQEIVKEIEHSLSMFQSVNHEVQSG
LKITEKTESSFHEISGMTNEIAGKLQTLNAAVEQLSNGSQEVSGAVQEIADVSRESTAGIQDIAASAEEQLASMEEISTS
SATLEQMAEDLRELTKKFKVK

Sequences:

>Translated_661_residues
MKKILEWFKHPSLSKRLAVSFLLILTLPVLILSGVSYYTAGGSIEDEIMRSARNSVDQLNEMIDQNIEKKADAVTYFSEE
IKEKTYKEKGQTSLRQKFEQYARQNKDVEAVFTGSEDGVYVQHPYTKMPDGYNPAERPWFKEAVEKKGEIIVTDPYTSAA
TGNTVITIAKQNKDGSGVAALSLNIDELIKATNDIKVGKDGFAFISSASKKYIAHPTIKAGTEGEGGWVDQVYGKGKGEF
KYTFEGKAKQMAFTTNKLTGWKIAGTMFSDEITNATKPVLYMALIVFSGALVLGGVLIFFIVRAISKPLNQLVLSAKNIS
SGDLTQQIEVRSNDEFGQLGKSFNDMAESLRTLIGTIQESVENVASSSEQLTASAEQTSQATEHITSAIEQFSNGAESQN
EKVETSSQQLSQMNDHLSEMTEVSESITEASIKSTEIAETGGELVQKTVGQMSSIDQSVKQAESVVKGLEGKSKDITSIL
RVINGIADQTNLLALNAAIEAARAGESGRGFSVVAEEVRKLAAQSADSAKEIEALIQEIVKEIEHSLSMFQSVNHEVQSG
LKITEKTESSFHEISGMTNEIAGKLQTLNAAVEQLSNGSQEVSGAVQEIADVSRESTAGIQDIAASAEEQLASMEEISTS
SATLEQMAEDLRELTKKFKVK
>Mature_661_residues
MKKILEWFKHPSLSKRLAVSFLLILTLPVLILSGVSYYTAGGSIEDEIMRSARNSVDQLNEMIDQNIEKKADAVTYFSEE
IKEKTYKEKGQTSLRQKFEQYARQNKDVEAVFTGSEDGVYVQHPYTKMPDGYNPAERPWFKEAVEKKGEIIVTDPYTSAA
TGNTVITIAKQNKDGSGVAALSLNIDELIKATNDIKVGKDGFAFISSASKKYIAHPTIKAGTEGEGGWVDQVYGKGKGEF
KYTFEGKAKQMAFTTNKLTGWKIAGTMFSDEITNATKPVLYMALIVFSGALVLGGVLIFFIVRAISKPLNQLVLSAKNIS
SGDLTQQIEVRSNDEFGQLGKSFNDMAESLRTLIGTIQESVENVASSSEQLTASAEQTSQATEHITSAIEQFSNGAESQN
EKVETSSQQLSQMNDHLSEMTEVSESITEASIKSTEIAETGGELVQKTVGQMSSIDQSVKQAESVVKGLEGKSKDITSIL
RVINGIADQTNLLALNAAIEAARAGESGRGFSVVAEEVRKLAAQSADSAKEIEALIQEIVKEIEHSLSMFQSVNHEVQSG
LKITEKTESSFHEISGMTNEIAGKLQTLNAAVEQLSNGSQEVSGAVQEIADVSRESTAGIQDIAASAEEQLASMEEISTS
SATLEQMAEDLRELTKKFKVK

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=355, Percent_Identity=34.6478873239437, Blast_Score=146, Evalue=5e-36,
Organism=Escherichia coli, GI2367378, Length=323, Percent_Identity=30.030959752322, Blast_Score=136, Evalue=4e-33,
Organism=Escherichia coli, GI1788195, Length=303, Percent_Identity=29.3729372937294, Blast_Score=122, Evalue=7e-29,
Organism=Escherichia coli, GI1788194, Length=356, Percent_Identity=29.7752808988764, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI1789453, Length=343, Percent_Identity=27.1137026239067, Blast_Score=105, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 71802; Mature: 71802

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKILEWFKHPSLSKRLAVSFLLILTLPVLILSGVSYYTAGGSIEDEIMRSARNSVDQLN
CHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCHHHHHHHHHHHHHHHHH
EMIDQNIEKKADAVTYFSEEIKEKTYKEKGQTSLRQKFEQYARQNKDVEAVFTGSEDGVY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEE
VQHPYTKMPDGYNPAERPWFKEAVEKKGEIIVTDPYTSAATGNTVITIAKQNKDGSGVAA
EECCCCCCCCCCCCCCCCHHHHHHHCCCCEEEECCCCCCCCCCEEEEEEECCCCCCCEEE
LSLNIDELIKATNDIKVGKDGFAFISSASKKYIAHPTIKAGTEGEGGWVDQVYGKGKGEF
EECCHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCE
KYTFEGKAKQMAFTTNKLTGWKIAGTMFSDEITNATKPVLYMALIVFSGALVLGGVLIFF
EEEECCCCHHHEEECCCCCCEEEECHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IVRAISKPLNQLVLSAKNISSGDLTQQIEVRSNDEFGQLGKSFNDMAESLRTLIGTIQES
HHHHHHHHHHHHHHHHCCCCCCCCHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VENVASSSEQLTASAEQTSQATEHITSAIEQFSNGAESQNEKVETSSQQLSQMNDHLSEM
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
TEVSESITEASIKSTEIAETGGELVQKTVGQMSSIDQSVKQAESVVKGLEGKSKDITSIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
RVINGIADQTNLLALNAAIEAARAGESGRGFSVVAEEVRKLAAQSADSAKEIEALIQEIV
HHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
KEIEHSLSMFQSVNHEVQSGLKITEKTESSFHEISGMTNEIAGKLQTLNAAVEQLSNGSQ
HHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHH
EVSGAVQEIADVSRESTAGIQDIAASAEEQLASMEEISTSSATLEQMAEDLRELTKKFKV
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC
K
C
>Mature Secondary Structure
MKKILEWFKHPSLSKRLAVSFLLILTLPVLILSGVSYYTAGGSIEDEIMRSARNSVDQLN
CHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCHHHHHHHHHHHHHHHHH
EMIDQNIEKKADAVTYFSEEIKEKTYKEKGQTSLRQKFEQYARQNKDVEAVFTGSEDGVY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEE
VQHPYTKMPDGYNPAERPWFKEAVEKKGEIIVTDPYTSAATGNTVITIAKQNKDGSGVAA
EECCCCCCCCCCCCCCCCHHHHHHHCCCCEEEECCCCCCCCCCEEEEEEECCCCCCCEEE
LSLNIDELIKATNDIKVGKDGFAFISSASKKYIAHPTIKAGTEGEGGWVDQVYGKGKGEF
EECCHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCE
KYTFEGKAKQMAFTTNKLTGWKIAGTMFSDEITNATKPVLYMALIVFSGALVLGGVLIFF
EEEECCCCHHHEEECCCCCCEEEECHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IVRAISKPLNQLVLSAKNISSGDLTQQIEVRSNDEFGQLGKSFNDMAESLRTLIGTIQES
HHHHHHHHHHHHHHHHCCCCCCCCHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VENVASSSEQLTASAEQTSQATEHITSAIEQFSNGAESQNEKVETSSQQLSQMNDHLSEM
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
TEVSESITEASIKSTEIAETGGELVQKTVGQMSSIDQSVKQAESVVKGLEGKSKDITSIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
RVINGIADQTNLLALNAAIEAARAGESGRGFSVVAEEVRKLAAQSADSAKEIEALIQEIV
HHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
KEIEHSLSMFQSVNHEVQSGLKITEKTESSFHEISGMTNEIAGKLQTLNAAVEQLSNGSQ
HHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHH
EVSGAVQEIADVSRESTAGIQDIAASAEEQLASMEEISTSSATLEQMAEDLRELTKKFKV
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8188684; 9384377 [H]