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The map label for this gene is htrA [H]

Identifier: 52785158

GI number: 52785158

Start: 1388112

End: 1389413

Strand: Reverse

Name: htrA [H]

Synonym: BLi01390

Alternate gene names: 52785158

Gene position: 1389413-1388112 (Counterclockwise)

Preceding gene: 52785169

Following gene: 52785155

Centisome position: 32.9

GC content: 48.39

Gene sequence:

>1302_bases
ATGATGGAATATAATAGAGAAGATCAGCTTGAAACAAAAAACGAACTCATCGTCTCCGATCAAAAGCCCGACCAGGCGAT
AAAAAAAGCAGAACAGCAAAAGCGGAGACTCTCGTGGATGACGCCGATTCTCAGCGGCATCATCGGAGGAAGCCTCGTTC
TCGGCGTCACGACATACCAGCATAGCAAAGACGAAACGGCCAATACATCCGTCCAGACGCAAACAAACGAGACGTCGAAC
TCATCGGCTTCTTCCACTAAAGCGAATACCGAAAAATTGTCCAGCACCAATTCGTCCGACATTTCTACAATGGTTGAAAA
TGTATCTCCCGCCATCGTCGGTATTTCAAACTATCAAAAACAAACAGAGAGCGGTATGTTCGGTTTTGAAAGCAACAGCA
GCAGCTCAAGCGAACAAGAAACAGGCACAGGCTCAGGTGTCATCTATAAAAAAGCAAACGGCAAAGCATACATTATTACA
AATAACCACGTTGTCGAAGGCGCGTCTAAACTGACGGTTTCCCTGTCCAACGGCAAAGAAGTGGAAGGTAAATTGCTGGG
CAGCGATTCGTTGACAGACCTTGCCGTTGTTGAAATTTCCGCTGATCACGTGGAAAAAGTCGCCTCTTTCGGCGATTCGT
CAAGCTTGAAAGCAGGCGAATCGGTGATCGCTATTGGAAACCCGCTCGGCAAAGATCTGTCCCGCACGGTGACACAAGGC
ATCATCAGCGGTGTTGATCGGACCGTTTCCGTAGATACATCCGCAGGCCAAACCGAGATGAACGTCATTCAAACCGACGC
GGCCATCAACCCCGGCAACAGCGGAGGCGCCCTTTTGAATACAAAGGGTGAAGTGATCGGCATCAACAGCATGAAAATCA
GTGAAAGCGGAGTAGAAGGCATCGGATTTGCGATTCCAAGCAATGATGTCAAACCGATTGCAGAAGAGCTGATGTCTAAA
GGAAAAATTGAGCGCCCGTTCATCGGAATCGGCATGATGGATCTTGAGCAGGTGCCGGAAAACTATCAAACAGGCACCCT
CGGATTAAGCGGCAGCCAGTTAAACAAAGGCGTCTACATCCGCCAGGTCGCTTCAGGCTCCCCAGCTGAAAAAGCGGGCC
TTAAAGAGAACGATGTCATCGTCAGCTTTAACGGAAAAGAAACCGATACAGGAAGCGCGCTGCGCAACCTTCTTTACAAC
GATGCAAAAATCGGGGATACGGTAAAGGTTACCCTCATTCGAAACGGCAAAACCATGACAAAACAAATCACCCTTGACCA
GAAAGAATCCGCATCATCTTAA

Upstream 100 bases:

>100_bases
CTTTTTCTTTGACAATTTCCCACAATGTTTTCATGTTTATCCCACAGTCTTTGTTTATGATTAAGGCATCAAAGGATATG
ATAGCAATAGGAGCGTGAAA

Downstream 100 bases:

>100_bases
CAGCATGCCCCCCTTTACGGGGCCGCCGGCTGTGCCGGATGCCTTTTATATAAAGACTCTGTTAGATTTGGATGTTGTTA
AATACGCAAAAATAAAGGGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MMEYNREDQLETKNELIVSDQKPDQAIKKAEQQKRRLSWMTPILSGIIGGSLVLGVTTYQHSKDETANTSVQTQTNETSN
SSASSTKANTEKLSSTNSSDISTMVENVSPAIVGISNYQKQTESGMFGFESNSSSSSEQETGTGSGVIYKKANGKAYIIT
NNHVVEGASKLTVSLSNGKEVEGKLLGSDSLTDLAVVEISADHVEKVASFGDSSSLKAGESVIAIGNPLGKDLSRTVTQG
IISGVDRTVSVDTSAGQTEMNVIQTDAAINPGNSGGALLNTKGEVIGINSMKISESGVEGIGFAIPSNDVKPIAEELMSK
GKIERPFIGIGMMDLEQVPENYQTGTLGLSGSQLNKGVYIRQVASGSPAEKAGLKENDVIVSFNGKETDTGSALRNLLYN
DAKIGDTVKVTLIRNGKTMTKQITLDQKESASS

Sequences:

>Translated_433_residues
MMEYNREDQLETKNELIVSDQKPDQAIKKAEQQKRRLSWMTPILSGIIGGSLVLGVTTYQHSKDETANTSVQTQTNETSN
SSASSTKANTEKLSSTNSSDISTMVENVSPAIVGISNYQKQTESGMFGFESNSSSSSEQETGTGSGVIYKKANGKAYIIT
NNHVVEGASKLTVSLSNGKEVEGKLLGSDSLTDLAVVEISADHVEKVASFGDSSSLKAGESVIAIGNPLGKDLSRTVTQG
IISGVDRTVSVDTSAGQTEMNVIQTDAAINPGNSGGALLNTKGEVIGINSMKISESGVEGIGFAIPSNDVKPIAEELMSK
GKIERPFIGIGMMDLEQVPENYQTGTLGLSGSQLNKGVYIRQVASGSPAEKAGLKENDVIVSFNGKETDTGSALRNLLYN
DAKIGDTVKVTLIRNGKTMTKQITLDQKESASS
>Mature_433_residues
MMEYNREDQLETKNELIVSDQKPDQAIKKAEQQKRRLSWMTPILSGIIGGSLVLGVTTYQHSKDETANTSVQTQTNETSN
SSASSTKANTEKLSSTNSSDISTMVENVSPAIVGISNYQKQTESGMFGFESNSSSSSEQETGTGSGVIYKKANGKAYIIT
NNHVVEGASKLTVSLSNGKEVEGKLLGSDSLTDLAVVEISADHVEKVASFGDSSSLKAGESVIAIGNPLGKDLSRTVTQG
IISGVDRTVSVDTSAGQTEMNVIQTDAAINPGNSGGALLNTKGEVIGINSMKISESGVEGIGFAIPSNDVKPIAEELMSK
GKIERPFIGIGMMDLEQVPENYQTGTLGLSGSQLNKGVYIRQVASGSPAEKAGLKENDVIVSFNGKETDTGSALRNLLYN
DAKIGDTVKVTLIRNGKTMTKQITLDQKESASS

Specific function: May be involved in processing, maturation, or secretion of extracellular enzymes [H]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=298, Percent_Identity=37.9194630872483, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI22129776, Length=313, Percent_Identity=33.2268370607029, Blast_Score=142, Evalue=5e-34,
Organism=Homo sapiens, GI24308541, Length=299, Percent_Identity=33.7792642140468, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI7019477, Length=346, Percent_Identity=30.635838150289, Blast_Score=125, Evalue=5e-29,
Organism=Escherichia coli, GI1789629, Length=336, Percent_Identity=36.3095238095238, Blast_Score=185, Evalue=6e-48,
Organism=Escherichia coli, GI1786356, Length=297, Percent_Identity=38.047138047138, Blast_Score=173, Evalue=2e-44,
Organism=Escherichia coli, GI1789630, Length=348, Percent_Identity=35.9195402298851, Blast_Score=169, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24646839, Length=294, Percent_Identity=35.7142857142857, Blast_Score=135, Evalue=6e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 45708; Mature: 45708

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMEYNREDQLETKNELIVSDQKPDQAIKKAEQQKRRLSWMTPILSGIIGGSLVLGVTTYQ
CCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEC
HSKDETANTSVQTQTNETSNSSASSTKANTEKLSSTNSSDISTMVENVSPAIVGISNYQK
CCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHCCCCEEEECHHHHH
QTESGMFGFESNSSSSSEQETGTGSGVIYKKANGKAYIITNNHVVEGASKLTVSLSNGKE
HHHCCCEEECCCCCCCCCHHCCCCCEEEEEECCCEEEEEECCEEECCCCEEEEEECCCCC
VEGKLLGSDSLTDLAVVEISADHVEKVASFGDSSSLKAGESVIAIGNPLGKDLSRTVTQG
CCEEEECCCCCCEEEEEEECHHHHHHHHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHH
IISGVDRTVSVDTSAGQTEMNVIQTDAAINPGNSGGALLNTKGEVIGINSMKISESGVEG
HHHCCCCEEEECCCCCCCEEEEEEECCCCCCCCCCCEEEECCCCEEEECCEEECCCCCCC
IGFAIPSNDVKPIAEELMSKGKIERPFIGIGMMDLEQVPENYQTGTLGLSGSQLNKGVYI
EEEECCCCCCHHHHHHHHHCCCCCCCEEECCHHHHHHCCCCCCCCEEECCCCCCCCCEEE
RQVASGSPAEKAGLKENDVIVSFNGKETDTGSALRNLLYNDAKIGDTVKVTLIRNGKTMT
EEECCCCCHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEEEEECCCEEE
KQITLDQKESASS
EEEECCCCCCCCC
>Mature Secondary Structure
MMEYNREDQLETKNELIVSDQKPDQAIKKAEQQKRRLSWMTPILSGIIGGSLVLGVTTYQ
CCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEC
HSKDETANTSVQTQTNETSNSSASSTKANTEKLSSTNSSDISTMVENVSPAIVGISNYQK
CCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHCCCCEEEECHHHHH
QTESGMFGFESNSSSSSEQETGTGSGVIYKKANGKAYIITNNHVVEGASKLTVSLSNGKE
HHHCCCEEECCCCCCCCCHHCCCCCEEEEEECCCEEEEEECCEEECCCCEEEEEECCCCC
VEGKLLGSDSLTDLAVVEISADHVEKVASFGDSSSLKAGESVIAIGNPLGKDLSRTVTQG
CCEEEECCCCCCEEEEEEECHHHHHHHHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHH
IISGVDRTVSVDTSAGQTEMNVIQTDAAINPGNSGGALLNTKGEVIGINSMKISESGVEG
HHHCCCCEEEECCCCCCCEEEEEEECCCCCCCCCCCEEEECCCCEEEECCEEECCCCCCC
IGFAIPSNDVKPIAEELMSKGKIERPFIGIGMMDLEQVPENYQTGTLGLSGSQLNKGVYI
EEEECCCCCCHHHHHHHHHCCCCCCCEEECCHHHHHHCCCCCCCCEEECCCCCCCCCEEE
RQVASGSPAEKAGLKENDVIVSFNGKETDTGSALRNLLYNDAKIGDTVKVTLIRNGKTMT
EEECCCCCHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEEEEECCCEEE
KQITLDQKESASS
EEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 10692364; 11133960; 11555295 [H]