BacMap

Definition	Bacillus licheniformis ATCC 14580, complete genome.
Accession	NC_006322
Length	4,222,645

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The map label for this gene is ykbA [H]

Identifier: 52785155

GI number: 52785155

Start: 1384582

End: 1385910

Strand: Reverse

Name: ykbA [H]

Synonym: BLi01387

Alternate gene names: 52785155

Gene position: 1385910-1384582 (Counterclockwise)

Preceding gene: 52785158

Following gene: 52785131

Centisome position: 32.82

GC content: 50.11

Gene sequence:

>1329_bases
ATGAATGCAGAAGCAAACGGACTAAAAAAAGAGATAGGCTTGTTATTTGCGCTATCTCTTGTGATTGGAACGATCATCGG
TTCCGGCGTGTTTATGAAGCCCGGCAGCGTGCTTTCCTATTCCGGAAACGCACAAATCGCTCTTTTCGCCTGGCTTCTCG
GCGGAATCTTGACGCTTGCCGGCGGGCTGACCATCGCTGAACTGGGCGCACAGATTCCGAAAACAGGCGGTCTTTACACA
TATCTTGAAGAAATTTACGGCGAGTTCTGGGGCTTCTTATGCGGCTGGGTGCAGATCATCATCTACGGACCGGCCATCAT
CGGCGCACTTGGATTATATTTCGGCTCGCTTGTGGCCAACTTGTTTTCCTGGGATAAATCCTGGACTGCACTCATCGGCA
TCATCACCGTCGCCTTTTTATGCATCGTCAACATCGTCGGAACAAAATACGGCGGAGCGGTTCAGACGATCACAACGATC
GGAAAGCTGATTCCCATTGTATGTATCATTGTGTTCGGTCTATGGCAGGGCGATGAATATATTTTCAGTTCGGTCACGGA
GAGCATCGCCAGCCAAAACTTCGGGGCGGCGGTATTGGCGACGCTATTCGCGTATGACGGCTGGATCCTTCTTGCAGCAC
TCGGCGGAGAAATGAAGAATCCGGAAAAAGTGCTTCCGAAAGCGATGACAGGCGGCATACTGATCGTCACTGCCTGCTAT
CTGTTCATTAACTTGGCGCTGCTTCACATTCTTCCTGCCGATCAGATTGTCAAGCTCGGCGAAAATGCGACAAGCACAGC
CGCGACCATGCTGTTCGGGCCGCTCGGCGGCAAGCTGATATCCATCGGAATTATCGTCAGCATCTTCGGCTGCTTAAACG
GAAAGGTTCTGTCTTTTCCGCGCGTGATCTTTGCGATGGCTGAGAAAAAACAGCTGCCTTTCTCCCGCTGGATCTCGCAT
GTTCATCCGGCATTCCATACGCCTTGGATCGCAGTCATCGTCCAGATGATTATCGCTGTCATTTTAATGATCATCAGCAA
TCCTGAAAAGCTGTCAGAGGTTTCGATTTTTATGATTTACATCTTCTATGTCATGGCGTTTTTCGCGGTATTTATTTTGC
GGAGACGGAAGAACGGCCAAGGAAGATCTTACAGCGTGCCGCTCTATCCTTACCTGCCTGTAGCGGCGATTCTCGGGTCA
TTGTTTGTCCTTGTCAGCACGCTCATCACAGACTTCTACAGCTGCCTGTGGTCGATCTTGATCGGTCTCGTCGGTCTCCC
GGTTTATTTTTGGATGAAAAAAAGAAATAAAAACGGCTCAGCTGCCTGA

Upstream 100 bases:

>100_bases
GAAAATCAGAAAATTTATTTAATTTTTCTTTTTTAAAAAAGGTATTACAATATAAAAATAGTTTTCTATGAAAGAGATCA
CATCAATGGGAGGCATAGCA

Downstream 100 bases:

>100_bases
GCCGAAGCCGCCGGCACATGAGCCCGGCGGTTTTTTTTTATCCCTTCACAGACCCGATCAGAATGCCTTTGGCAAAATGC
TTCTGCAAAAACGGGTACAC

Product: YkbA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MNAEANGLKKEIGLLFALSLVIGTIIGSGVFMKPGSVLSYSGNAQIALFAWLLGGILTLAGGLTIAELGAQIPKTGGLYT
YLEEIYGEFWGFLCGWVQIIIYGPAIIGALGLYFGSLVANLFSWDKSWTALIGIITVAFLCIVNIVGTKYGGAVQTITTI
GKLIPIVCIIVFGLWQGDEYIFSSVTESIASQNFGAAVLATLFAYDGWILLAALGGEMKNPEKVLPKAMTGGILIVTACY
LFINLALLHILPADQIVKLGENATSTAATMLFGPLGGKLISIGIIVSIFGCLNGKVLSFPRVIFAMAEKKQLPFSRWISH
VHPAFHTPWIAVIVQMIIAVILMIISNPEKLSEVSIFMIYIFYVMAFFAVFILRRRKNGQGRSYSVPLYPYLPVAAILGS
LFVLVSTLITDFYSCLWSILIGLVGLPVYFWMKKRNKNGSAA

Sequences:

>Translated_442_residues
MNAEANGLKKEIGLLFALSLVIGTIIGSGVFMKPGSVLSYSGNAQIALFAWLLGGILTLAGGLTIAELGAQIPKTGGLYT
YLEEIYGEFWGFLCGWVQIIIYGPAIIGALGLYFGSLVANLFSWDKSWTALIGIITVAFLCIVNIVGTKYGGAVQTITTI
GKLIPIVCIIVFGLWQGDEYIFSSVTESIASQNFGAAVLATLFAYDGWILLAALGGEMKNPEKVLPKAMTGGILIVTACY
LFINLALLHILPADQIVKLGENATSTAATMLFGPLGGKLISIGIIVSIFGCLNGKVLSFPRVIFAMAEKKQLPFSRWISH
VHPAFHTPWIAVIVQMIIAVILMIISNPEKLSEVSIFMIYIFYVMAFFAVFILRRRKNGQGRSYSVPLYPYLPVAAILGS
LFVLVSTLITDFYSCLWSILIGLVGLPVYFWMKKRNKNGSAA
>Mature_442_residues
MNAEANGLKKEIGLLFALSLVIGTIIGSGVFMKPGSVLSYSGNAQIALFAWLLGGILTLAGGLTIAELGAQIPKTGGLYT
YLEEIYGEFWGFLCGWVQIIIYGPAIIGALGLYFGSLVANLFSWDKSWTALIGIITVAFLCIVNIVGTKYGGAVQTITTI
GKLIPIVCIIVFGLWQGDEYIFSSVTESIASQNFGAAVLATLFAYDGWILLAALGGEMKNPEKVLPKAMTGGILIVTACY
LFINLALLHILPADQIVKLGENATSTAATMLFGPLGGKLISIGIIVSIFGCLNGKVLSFPRVIFAMAEKKQLPFSRWISH
VHPAFHTPWIAVIVQMIIAVILMIISNPEKLSEVSIFMIYIFYVMAFFAVFILRRRKNGQGRSYSVPLYPYLPVAAILGS
LFVLVSTLITDFYSCLWSILIGLVGLPVYFWMKKRNKNGSAA

Specific function: Exhibits an obligate exchange activity for serine, threonine and aromatic amino acids [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family [H]

Homologues:

Organism=Homo sapiens, GI115648063, Length=438, Percent_Identity=30.1369863013699, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI115648022, Length=438, Percent_Identity=30.1369863013699, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI33286428, Length=444, Percent_Identity=31.981981981982, Blast_Score=169, Evalue=7e-42,
Organism=Homo sapiens, GI186910308, Length=436, Percent_Identity=29.8165137614679, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI186910306, Length=436, Percent_Identity=29.8165137614679, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI186910304, Length=436, Percent_Identity=29.8165137614679, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI187423910, Length=455, Percent_Identity=29.8901098901099, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI7657591, Length=455, Percent_Identity=29.8901098901099, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI7657683, Length=444, Percent_Identity=29.0540540540541, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI9790235, Length=452, Percent_Identity=31.6371681415929, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI71979932, Length=454, Percent_Identity=30.3964757709251, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI71999149, Length=417, Percent_Identity=24.9400479616307, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI4507047, Length=437, Percent_Identity=22.883295194508, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI258614005, Length=430, Percent_Identity=23.2558139534884, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI258614003, Length=430, Percent_Identity=23.2558139534884, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI33286430, Length=256, Percent_Identity=28.90625, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI258645169, Length=430, Percent_Identity=22.7906976744186, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI181337167, Length=395, Percent_Identity=24.3037974683544, Blast_Score=76, Evalue=6e-14,
Organism=Escherichia coli, GI87082250, Length=454, Percent_Identity=26.2114537444934, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI2367353, Length=403, Percent_Identity=27.7915632754342, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1786694, Length=426, Percent_Identity=23.943661971831, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI87081708, Length=476, Percent_Identity=22.6890756302521, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787890, Length=453, Percent_Identity=22.7373068432671, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786789, Length=420, Percent_Identity=23.0952380952381, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790584, Length=326, Percent_Identity=26.3803680981595, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1786908, Length=386, Percent_Identity=24.3523316062176, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI87081915, Length=417, Percent_Identity=23.5011990407674, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1786602, Length=478, Percent_Identity=21.1297071129707, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1786302, Length=452, Percent_Identity=22.787610619469, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI71993915, Length=402, Percent_Identity=28.3582089552239, Blast_Score=134, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI17540018, Length=407, Percent_Identity=29.2383292383292, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI71990446, Length=372, Percent_Identity=28.494623655914, Blast_Score=128, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI17568033, Length=444, Percent_Identity=26.5765765765766, Blast_Score=125, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI71995382, Length=459, Percent_Identity=25.7080610021786, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71995388, Length=464, Percent_Identity=25.4310344827586, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI32566699, Length=317, Percent_Identity=29.9684542586751, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71982612, Length=442, Percent_Identity=26.0180995475113, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI71982608, Length=442, Percent_Identity=26.0180995475113, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17531343, Length=473, Percent_Identity=23.8900634249471, Blast_Score=111, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI32566695, Length=435, Percent_Identity=25.2873563218391, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI193208714, Length=435, Percent_Identity=25.2873563218391, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17532491, Length=408, Percent_Identity=26.4705882352941, Blast_Score=106, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17533459, Length=410, Percent_Identity=25.8536585365854, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71982623, Length=267, Percent_Identity=28.0898876404494, Blast_Score=86, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6321751, Length=345, Percent_Identity=26.3768115942029, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6321492, Length=362, Percent_Identity=22.9281767955801, Blast_Score=91, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24651635, Length=430, Percent_Identity=28.1395348837209, Blast_Score=163, Evalue=3e-40,
Organism=Drosophila melanogaster, GI24651633, Length=430, Percent_Identity=28.1395348837209, Blast_Score=163, Evalue=3e-40,
Organism=Drosophila melanogaster, GI45550968, Length=439, Percent_Identity=28.0182232346241, Blast_Score=154, Evalue=9e-38,
Organism=Drosophila melanogaster, GI19921172, Length=439, Percent_Identity=28.0182232346241, Blast_Score=154, Evalue=9e-38,
Organism=Drosophila melanogaster, GI24641993, Length=387, Percent_Identity=29.1989664082687, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24641995, Length=387, Percent_Identity=29.1989664082687, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI221331183, Length=447, Percent_Identity=29.7539149888143, Blast_Score=149, Evalue=5e-36,
Organism=Drosophila melanogaster, GI17647653, Length=447, Percent_Identity=29.7539149888143, Blast_Score=149, Evalue=5e-36,
Organism=Drosophila melanogaster, GI24664379, Length=447, Percent_Identity=29.7539149888143, Blast_Score=149, Evalue=5e-36,
Organism=Drosophila melanogaster, GI21357367, Length=455, Percent_Identity=26.5934065934066, Blast_Score=148, Evalue=6e-36,
Organism=Drosophila melanogaster, GI24667468, Length=380, Percent_Identity=26.3157894736842, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI221512776, Length=413, Percent_Identity=23.728813559322, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24666159, Length=413, Percent_Identity=23.728813559322, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI281366235, Length=373, Percent_Identity=24.3967828418231, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI116007820, Length=373, Percent_Identity=24.3967828418231, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24668806, Length=417, Percent_Identity=23.5011990407674, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21356285, Length=417, Percent_Identity=23.5011990407674, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24668802, Length=417, Percent_Identity=23.5011990407674, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI116007818, Length=376, Percent_Identity=25.531914893617, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI85725152, Length=376, Percent_Identity=25.531914893617, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI161077963, Length=417, Percent_Identity=24.220623501199, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 47814; Mature: 47814

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAEANGLKKEIGLLFALSLVIGTIIGSGVFMKPGSVLSYSGNAQIALFAWLLGGILTLA
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEEECCCCHHHHHHHHHHHHHHHH
GGLTIAELGAQIPKTGGLYTYLEEIYGEFWGFLCGWVQIIIYGPAIIGALGLYFGSLVAN
CCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFSWDKSWTALIGIITVAFLCIVNIVGTKYGGAVQTITTIGKLIPIVCIIVFGLWQGDEY
HHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHH
IFSSVTESIASQNFGAAVLATLFAYDGWILLAALGGEMKNPEKVLPKAMTGGILIVTACY
HHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHH
LFINLALLHILPADQIVKLGENATSTAATMLFGPLGGKLISIGIIVSIFGCLNGKVLSFP
HHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHH
RVIFAMAEKKQLPFSRWISHVHPAFHTPWIAVIVQMIIAVILMIISNPEKLSEVSIFMIY
HHHHHHHHHHCCCHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
IFYVMAFFAVFILRRRKNGQGRSYSVPLYPYLPVAAILGSLFVLVSTLITDFYSCLWSIL
HHHHHHHHHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGLVGLPVYFWMKKRNKNGSAA
HHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNAEANGLKKEIGLLFALSLVIGTIIGSGVFMKPGSVLSYSGNAQIALFAWLLGGILTLA
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEEECCCCHHHHHHHHHHHHHHHH
GGLTIAELGAQIPKTGGLYTYLEEIYGEFWGFLCGWVQIIIYGPAIIGALGLYFGSLVAN
CCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFSWDKSWTALIGIITVAFLCIVNIVGTKYGGAVQTITTIGKLIPIVCIIVFGLWQGDEY
HHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHH
IFSSVTESIASQNFGAAVLATLFAYDGWILLAALGGEMKNPEKVLPKAMTGGILIVTACY
HHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHH
LFINLALLHILPADQIVKLGENATSTAATMLFGPLGGKLISIGIIVSIFGCLNGKVLSFP
HHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHH
RVIFAMAEKKQLPFSRWISHVHPAFHTPWIAVIVQMIIAVILMIISNPEKLSEVSIFMIY
HHHHHHHHHHCCCHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
IFYVMAFFAVFILRRRKNGQGRSYSVPLYPYLPVAAILGSLFVLVSTLITDFYSCLWSIL
HHHHHHHHHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGLVGLPVYFWMKKRNKNGSAA
HHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]